Articles tagged with Influenza
Researchers discovered that club cells, which normally protect against inhaled microbes, contribute to prolonged inflammation during flu infection. Targeting these cells may help shorten flu symptoms by reducing lung damage.
A Vanderbilt-led study published in the New England Journal of Medicine found that the high-dose flu vaccine is 24% more effective than the standard-dose vaccine in protecting persons ages 65 and over against influenza illness. The study, which enrolled 31,989 participants, showed that the high-dose trivalent vaccine induces significan...
A study of 6,800 outpatients found antiviral therapy was given to only 19% of those at high risk for complications, while antibiotics were prescribed to 30%. The findings suggest a need for increased education on appropriate use in outpatient settings.
Researchers found that prior colonization by Streptococcus pneumoniae protected mice from severe disease and pneumonia. The protective effect was linked to the bacterial virulence factor pneumolysin, which reduced inflammation in the lungs.
University of Chicago scientists have developed new multiscale simulations that reveal the proton permeation mechanism in influenza A, a crucial step in viral replication. This breakthrough could lead to the development of more effective and targeted treatments against the flu.
A California-based study reveals a strong connection between hospital healthcare personnel influenza vaccination and the rate of influenza-like illnesses in surrounding communities. For every 15 vaccinated healthcare workers, one fewer case of flu is reported in the community.
Researchers found that SOCS4 suppresses the immune system's runaway reaction to flu infection, reducing the risk of cytokine storms and related deaths. The discovery provides a potential means of minimizing the impact of flu pandemics.
A new study from the University of Liverpool surveyed 1,821 people in Guangdong to understand how diseases such as bird flu spread among communities. The research found that people met around ten others each day and spent between five and ten hours a day with other people.
A study by University of Houston researchers found that Google Flu Trend overestimated flu cases in the US by up to 50% and failed to accurately predict levels in previous seasons. The researchers suggest combining big data with traditional methodologies for a more accurate understanding of human behavior.
A global inventory of flu strains in birds has identified over 116 avian flu strains in wild birds, twice the number found in domestic birds. The study also reveals patterns of flu diversity in different bird hosts, with some strains specific to certain species.
A new study suggests that self-administration of the flu vaccine via a microneedle patch could be feasible and increase vaccination rates. The study found that nearly all participants were able to accurately apply the patches, with significant increases in willingness to receive the vaccine.
A new study published in Nature Climate Change found no link between warmer winters and reduced excess winter death rates in the UK. Instead, flu activity was identified as the main cause of year-to-year variation in winter mortality.
A study by St. Jude Children's Research Hospital identified an immune signature that predicts poor flu outcomes in patients, who are more likely to develop severe symptoms and suffer from complications. The findings also explain why infants and toddlers are at elevated risk for flu-related issues.
A new study published in Diabetologia confirms that working-age adults with diabetes are at a higher risk of influenza compared to non-diabetic individuals. The research suggests that vaccinating this group could be cost-effective and mitigate healthcare costs associated with flu-related hospitalizations.
Researchers found that a new adjuvant improved flu vaccine effectiveness in mice and showed promise for the elderly. The study also highlighted the importance of characterizing immune responses following intra-nasal vaccinations, particularly with novel adjuvants.
The new website provides weekly predictions for US seasonal flu rates in 94 cities, based on a scientifically validated system. Flu cases are forecast to peak in January, with some areas already experiencing the worst of the outbreak.
Researchers at the University of Melbourne have identified a genetic marker that signals increased susceptibility to emerging influenza strains. This breakthrough allows clinicians to develop early intervention strategies for high-risk patients.
Researchers at Tufts University found that wolfberries can increase immune system activity and protect against the flu virus in older mice who received the flu vaccine. The study suggests potential benefits for humans as well, where age-related weakening of the immune system reduces vaccine effectiveness.
Scientists successfully predicted the timing of the 2012-2013 influenza season up to nine weeks in advance, providing actionable information for officials and the public. The flu forecasting system, using combined data from Google Flu Trends and CDC reports, outperformed alternate schemes and showed regional differences in accuracy.
Researchers at UC Davis and University of Rochester found that having health insurance increases use of preventive services like flu shots and health screenings, but does not affect risky health behaviors. The study contradicts a common concern that expanding healthcare coverage may encourage riskier behavior.
Researchers have identified that seasonal flu escapes immunity by making just a single amino acid substitution, occurring at seven specific places on its surface. This new understanding could lead to more effective flu vaccines.
A study found that Amphotericin B, a widely used anti-fungal medicine, neutralizes an important anti-viral protein IFITM3, making cells more susceptible to flu infection. This increases the risk of flu infections in patients with already compromised immune systems.
Research suggests that northern China conduct annual vaccinations starting in October, while southernmost provinces vaccinate in February. The study aims to optimize the timing of future vaccination programs and provides a clear picture of influenza seasonally across China.
A social media program by San Diego State University professor Ming-Hsiang Tsou analyzed tweets for keywords 'flu' and 'influenza' to identify outbreaks. The algorithm detected daily correlations between tweet patterns and regional reports, with five cities showing the strongest correlations.
Diagnosing influenza with a rapid test reduces the need for unnecessary antibiotics, lab tests, and antiviral medications. It also increases the prescription of antiviral drugs, leading to more targeted and efficient care in emergency departments.
Individuals with a known gelatin allergy can experience mild to severe reactions from the flu shot, including hives, sneezing, and difficulty breathing. Precautions should be taken when receiving the vaccine, such as having a board-certified allergist administer it.
Allergy expert Dr. David Stukus debunks common myths, including artificial dyes, vaccines, at-home blood tests, dietary restrictions, and pet allergies. He emphasizes the importance of consulting a board-certified allergist for proper evaluation and treatment.
Two student-developed mobile apps, FoodFeed and FL•U, have been created to combat health threats. FoodFeed provides alerts on food recalls, illness outbreaks and health code violations, while FL•U allows users to share flu-like symptoms and view localized outbreak maps.
Researchers at Whitehead Institute discovered that the flu virus infects host cells by killing off immune system's best-equipped cells that can neutralize the virus. This allows the virus to replicate efficiently before the immune system mounts a second wave of defense.
A UK-based study found that expanding flu vaccination policies to include children aged 5-16 could significantly reduce the number of flu infections and deaths. The current policy targets adults over 65 and high-risk groups, which has shown success in reducing morbidity and mortality.
Researchers at Virginia Tech aim to improve understanding of how environmental conditions affect the influenza virus's ability to survive and infect others while airborne. The project seeks to clarify why humidity affects the virus's transmission.
Scientists at Fred Hutchinson Cancer Center have uncovered a new mechanism by which influenza viruses infect cells, utilizing the protein neuraminidase instead of hemagglutinin. This discovery may have implications for developing immunity against the flu and could lead to new treatments.
A McMaster study found that new mothers and obese individuals are more susceptible to severe influenza outcomes, despite not being considered high-risk groups. The research highlights the need for precise definition of risk factors to optimize vaccine allocation during epidemics.
Research published in the journal Heart suggests that flu jab reduces heart attack risk by 45% in middle-aged individuals with narrowed arteries. The study found that flu was an underlying cause of heart attacks in hospital patients, and that vaccination may be protective.
Researchers found that only one type of alveolar macrophage can fend off secondary bacterial infections, which are depleted during flu infections. The study aims to develop strategies for treatment and immunotherapies to supplement natural defenses.
A new study by St. Michael's Hospital found that the flu shot is effective in preventing the flu, even if the virus going around does not match the vaccine. The review of over 40 years of data showed significant protection against both matched and mismatched flu strains.
According to a study published in PLOS ONE, the flu vaccine likely prevented approximately 13 million illnesses and over 110,000 hospitalizations in the US between 2006 and 2011. The researchers estimated this impact based on vaccination coverage and vaccine effectiveness.
A Pitt simulation found that universal access to paid sick days reduces flu cases in the workplace by nearly 6%, more effective for small workplaces. Giving employees one or two flu days resulted in a 25-40% decrease in influenza infections due to workplace transmission.
A new report suggests that vaccinating more children and young adults for influenza could significantly reduce the number of lives lost and economic burden associated with seasonal influenza. The study's findings suggest that programs targeting these age groups would have the best payoff in breaking the annual transmission cycle.
A four-year analysis of Loyola University Health System's mandatory flu vaccination policy shows that workers do not quit due to the requirement. The policy led to a 99 percent compliance rate and enhanced patient safety.
A four-year analysis found that mandatory influenza vaccination in a university medical center led to a near-universal vaccination rate, with fewer than 15 employees out of 8,000 choosing termination over vaccination. The policy also enhanced patient and staff safety, resulting in improved outcomes.
A new study found that school-located vaccination clinics increased flu vaccination rates among children by 13.2 percentage points, despite higher initial costs. The program may be a cost-effective way to broaden access to flu vaccines for children, particularly in primary-care settings.
A randomized trial found that giving double doses of oseltamivir to patients with severe influenza infection offers no clinical or virological advantages over a standard dose. The study has implications for global guidelines on clinical management and stockpiling drugs for pandemic preparedness.
A study by UCLA Center for Health Policy Research found that Californians with chronic conditions who have a regular doctor coordinating their care are more likely to get flu shots and receive preventive treatment. This 'medical home' model can help prevent chronic health conditions and reduce healthcare spending.
A Johns Hopkins fellow argues that the US public health agency's message on influenza vaccines may be overstated, with limited evidence supporting the claim that vaccines save lives. He also questions the effectiveness of vaccines in reducing elderly deaths and highlights potential side effects.
A recent NIH-funded study found that pregnant mothers' exposure to the flu may quadruple their child's risk for developing bipolar disorder. The research suggests a potential shared underlying cause with schizophrenia, and emphasizes the importance of preventive measures such as flu vaccination.
Scientists at the University of Maryland School of Medicine discovered a promising new treatment for influenza, Eritoran, which protects mice from death after infection. The findings are crucial in light of the spreading H7N9 flu strain in China, with 17 deaths reported.
Research by scientists from the Max F. Perutz Laboratories suggests that treating flu-related tissue damage can aid in combating co-infections with bacteria like Legionella pneumophila, which cause pneumonia and potentially fatal outcomes.
A new detection test using nanotechnology may make food contamination testing more rapid and accurate, with a sensitivity one hundred times greater than the standard method. The test can detect toxins in as little as one hour, compared to four to six hours for current methods.
Researchers discovered genetic changes enabling H5N1 bird flu to replicate in mammalian noses, paving the way for more effective vaccines against human transmission. The findings suggest that specific mutations can mediate the spread of bird flu between humans.
A recent NIH study found a strong association between cold-dry and humid-rainy climates and seasonal influenza epidemics worldwide. The research used a climate-based model to map influenza activity globally, accounting for diverse seasonal patterns in temperate, subtropical, and tropical regions.
A University of Maryland study found that wearing a surgical mask can significantly reduce the release of infectious flu virus in even the smallest airborne droplets. The research provides new evidence on the importance of using masks to prevent the spread of influenza, particularly among vulnerable populations.
Healthcare workers who wear special fitted face masks are less likely to get clinical respiratory and bacterial infections. The study, published in the American Journal of Critical Care Medicine, found that continuous use of N95 masks provides significant protection against both types of infections.
Researchers have developed a new antiviral drug that prevents flu viruses from removing sugars on cell surfaces, blocking infection. The drug is effective against resistant strains and may also protect against future variants.
A new class of influenza drug has been shown to prevent the flu virus from spreading and successfully treat mice with lethal strains. The drug works by attaching itself to the virus's molecular machinery, rendering it useless.
The NIH is sponsoring three clinical trials to test new treatments for influenza, including oseltamivir, combination antiviral drugs and plasma enriched with anti-influenza antibodies. The trials aim to improve treatment options for people with severe illness or chronic health conditions.
A study found that 26% of influenza patients released virus into the air during routine care, with some 'super-emitters' transmitting more than 32 times more virus. Current infection control recommendations may not be adequate to protect providers from influenza exposure.
A new study suggests that healthcare providers may need to wear fitted respirators for routine care of flu patients due to the high infectiousness of some individuals. The researchers found that small particles can float in the air for hours and travel long distances, making non-fitted masks ineffective.
A recent study suggests that climate change could result in earlier onset and increased severity of flu seasons. The research team analyzed waves of influenza and climate patterns in the US from 1997-1998 to present, indicating a pattern where warm winters are followed by heavy flu seasons.
A new tweet-screening method developed by Johns Hopkins researchers delivers real-time data on flu cases, filtering out online chatter that is not linked to actual flu infections. The system produces accurate results comparable to government disease data, making it a valuable tool for public health officials.