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Any prime-boost mix of injected or spray flu vaccine shields toddlers

A new study by NIH-funded researchers found that a prime-boost mix of injected or spray flu vaccine provides the broadest immune response in young children. The study also found that nasal spray vaccine stimulates a wide array of immune T cells, which may be important for protection against diverse flu strains.

SourceNIH/National Institute of Allergy and Infectious Diseases·JournalThe Journal of Infectious Diseases·DateAug 16, 2011

Quick test can predict immune responses to flu shots

Researchers have developed a method to predict whether someone will produce high levels of antibodies against a flu shot, allowing for the rapid development of vaccines and monitoring of suboptimal immune responses in vulnerable populations. The test uses gene activity data to identify predictive signatures with up to 90% accuracy.

SourceEmory Health Sciences·JournalNature Immunology·DateJul 10, 2011

Coseasonality of influenza and invasive pneumococcal disease

A study found that infection with influenza likely increases the incidence of invasive pneumococcal disease (IPD). Influenza infection may increase the short-term risk of bacterial invasion in individuals already colonized with Streptococcus pneumoniae, which causes IPD. This suggests that some cases of IPD could be attributable to inf...

SourcePLOS·JournalPLOS Medicine·DateJun 7, 2011

Nasal spray vaccines more effective against flu

Research suggests that combining standard vaccines with interleukin-12 (IL-12) can induce high levels of protection against respiratory pathogens, including influenza virus and pneumococcal bacteria. This method could provide a non-invasive alternative to injections, offering improved protection against flu and other diseases.

Flu helps spread pneumonia

Researchers have found that flu virus infection is necessary for pneumococcal bacteria to efficiently spread between individuals. The study has implications for managing influenza pandemics and reducing pneumococcal infections in young children, who are highly susceptible.

Research predicts future evolution of flu viruses

Researchers developed a new approach to predict which flu strain will be prevalent in a given year by tracking pairs of genetic changes. This method offers insights into epistasis, where mutations interact with each other to affect the virus's fitness. By analyzing these interactions, scientists can gain early warnings of emerging muta...

SourcePLOS·JournalPLOS Genetics·DateFeb 17, 2011

Flu vaccination disparities exacerbated by supply problems

Research from the University of Rochester Medical Center reveals that gaps in seasonal influenza vaccination rates between elderly whites, African-Americans, and Hispanics widen when vaccine supply is delayed or decreased. The study found significant declines in vaccination rates among minority groups during years with shortages.

SourceUniversity of Rochester Medical Center·JournalAmerican Journal of Preventive Medicine·DateDec 6, 2010

Dry winters linked to seasonal outbreaks of influenza

A new study published in PLoS Biology found that absolute humidity is the underlying cause of seasonal influenza outbreaks. The researchers used 31 years of observed data to drive a mathematical model of influenza and found that the model simulations reproduced the observed seasonal cycle of influenza throughout the United States.

SourcePLOS·JournalPLOS Biology·DateFeb 22, 2010

Can kitchen spoons be dangerous spoons?

A new Cornell study reveals that using kitchen spoons to measure liquid medicine can lead to significant inaccuracies. Participants under-dosed by an average of 8%, while those using larger spoons over-dosed by 12%. Experts recommend using precise measuring devices instead.

SourceCornell Food & Brand Lab·JournalAnnals of Internal Medicine·DateJan 4, 2010

Women at risk from vitamin A deficiency

A new study reveals that nearly half of UK women have a genetic variation reducing their ability to produce sufficient vitamin A. Vitamin A plays a vital role in immune system strengthening and preventing infections. The study found that younger women are at particular risk, highlighting the importance of adequate diet for this nutrient.

SourceNewcastle University·JournalThe FASEB Journal·DateNov 18, 2009

Older patients with dementia at increased risk for flu mortality

A study published in Journal of the American Geriatrics Society found that older patients with dementia are diagnosed with flu less frequently, have shorter hospital stays, but a higher rate of death. The study highlights the need for refined guidelines on flu immunization and treatment in this vulnerable population.

SourceTufts University, Health Sciences Campus·JournalJournal of the American Geriatrics Society·DateOct 27, 2009

Flu shots not to be sneezed at

A new study found that nearly half of high-risk American adults who intend to get vaccinated against seasonal flu actually do, but nearly 45% cite a perceived lack of need as the main reason for not being vaccinated. The researchers suggest that educating these individuals about the benefits of vaccination and making it more convenient...

SourceSpringer·JournalJournal of General Internal Medicine·DateOct 22, 2009

Pregnancy and the flu: A link to schizophrenia

A new study found that fetal exposure to influenza B virus may lead to cognitive problems at age 7 among children later diagnosed with psychosis. The association was not observed in children who did not develop psychotic disorders.

SourceElsevier·JournalBiological Psychiatry·DateJun 9, 2009