Researchers at Clemson University have discovered a potential new therapeutic target for hidradenitis suppurativa, an immune disease causing painful skin lesions and inflammation. The study identifies CD2 as a key immune receptor with elevated expression on T cells and innate lymphoid cells in affected skin tissue.
Researchers found that facemask connections affect helmet performance, leading to increased impact forces. The team developed a novel testing method to measure facemask strength without destruction.
For the first time, researchers have demonstrated how mechanical forces affect gene expression by showing that RNAP polymerase remains on the DNA template and can be pulled to start a subsequent cycle of transcription. This force-directed recycling mechanism can change the relative abundance of adjacent genes.
The International Society of Biomechanics provides recommendations for wearables-based motion capture technology, addressing sensor calibration and experimental protocols. The guidelines aim to improve accuracy and quality in human motion analysis applications.
A research team led by Clemson University Professor Shahid Mukhtar aims to identify natural biological solutions through the microbiome to help soybeans survive extreme heat and drought. The study will focus on the cellular level, soil microbiomes, and plant responses to environmental stresses.
Researchers, including Assistant Professor James Lewis, are studying the evolution of butterfly wing color patterns as a model for understanding population adaptation to environmental changes. The study aims to understand why some Heliconiine butterflies lose their mimicry phenotype and how this affects their survival.
Researchers developed an ex vivo gene-editing protocol to treat hereditary tyrosinemia type 1 using liver cell therapy. The study showed robust engraftment and expansion of transplanted gene-edited hepatocytes in recipient mice, correcting disease indicators such as normalized tyrosine, phenylalanine levels.
Researchers at Clemson University have developed a new noncentrosymmetric triangular-lattice magnet, CaMnTeO6, which displays strong quantum fluctuations and nonlinear optical responses. This breakthrough material has the potential to lead to advancements in solid-state quantum computing, spin-based electronics, resilient climate chang...
Researchers at Clemson University have developed a simulation-based optimization approach to overcome challenges in vitrification of larger tissues. The new technology results in high viability rates for vitreous grafts, making them suitable for transplantation.
Researchers at Clemson University discovered that certain Neanderthal-derived genetic variations are more common in people with autism than in the general population. These findings suggest long-term effects of ancient human hybridization on brain organization and function, potentially leading to earlier diagnostics.
A Clemson astrophysicist's research offers the most stringent constraints yet on dark matter's fundamental nature. The study reveals a small hint of a signal that could be confirmed in the next decade if real.
Researchers have detected tellurium in a kilonova afterglow, indicating that neutron star mergers can create rare heavy elements. This discovery sheds light on the formation of elements heavier than iron and provides new insights into the universe's chemical composition.
A newly discovered nemertean worm, Carcinonemertes conanobrieni, affects reproductive performance of Caribbean spiny lobsters. The parasite impacts embryo mortality and reproductive output, contributing to decreased landings of the ecologically significant species.
A Clemson team created a novel metal-organic framework with combined conduction pathways, outperforming traditional MOFs. This breakthrough could advance modern electronics and energy technologies.
Researchers found that 89% of Dominica's trees sustained damage from Hurricane Maria, but only 10% were immediately killed. The study suggests that forests in hurricane-prone regions can resist extreme weather events due to their adapted structure and composition.
A team of Clemson researchers has developed a new method to evaluate the efficiency of thermoelectric materials, called the figure-of-merit (zT), which considers temperature, electrical conductivity, and thermal conductivity. The new method uses Peltier cooling to measure zT with higher resolution and accuracy.
A team of scientists led by Clemson University's Marco Ajello has provided conclusive evidence that astrophysical neutrinos come from blazars, which are powerful black holes. This breakthrough resolves the long-standing question about the origin of high-energy cosmic rays.
Researchers from Clemson University have discovered a promising therapy for toxoplasmosis, a disease caused by the microscopic protozoa Toxoplasma gondii. The team has enlisted an unlikely ally - the herbicide oxadiazon - in the fight against the single-celled parasite.
Researchers investigate how enzymes regulate metabolism, weight gain, and liver disease, revealing diet's significant role in obesity and altered lipid profiles. The study also shows that age affects metabolic processes, leading to weight gain, increased fat storage, and unhealthy liver changes.
Researchers identified glacial refugia for Campanula americana and found that populations nearest the refugia had highest potential for speciation. This discovery highlights the importance of conserving habitats in Southeastern regions.
Researchers at Clemson University and SSSIHL discovered a novel way to combine curcumin and gold nanoparticles to create an electrode that efficiently converts ethanol into electricity. The discovery brings replacing hydrogen as a fuel cell feedstock one step closer, with potential applications in sensors and supercapacitors.
Research at Clemson University reveals that flowers use UV-absorbing chemicals to create a 'bulls-eye' effect for pollinating insects, aiding survival. Plants adapt to different environments by producing varying amounts of UV-blocking or absorbing chemicals.
A study by Clemson University analyzed 5 million individuals in Northern California and found that residents with access to nearby green spaces experienced lower healthcare costs. The research highlights the importance of incorporating green spaces into urban planning to improve public health outcomes.
Researchers at Clemson University have identified a genetic variation associated with congenital idiopathic megaesophagus (CIM) in German shepherd dogs, which is often fatal if left untreated. A genetic test using melanin-concentrating hormone receptor 2 and dog's sex can predict the risk of CIM with 75% accuracy.
Researchers will study temporomandibular joint function and disorders, aiming to understand the stresses on the joint before degeneration and develop new treatments. The project is a collaboration between Clemson University, Medical University of South Carolina, and National Institute of Dental and Craniofacial Research.
Researchers found that tropical forests can recover soil fertility in under 10 years, plant functioning in less than 25 years, and species diversity in 60 years. Allowing secondary forests to regrow can be an important part of tropical forest conservation, providing a toolkit for ecosystem restoration.
A study led by Clemson University geneticist Allison Hickman has identified 11 high-priority genes associated with uterine cancer. These genes are potential targets for drug therapies, offering new hope for effective treatment options.
A Clemson-led study aims to accelerate crop breeding by editing the cotton genome in microgravity. The research seeks to understand gene function and develop new methods for precision genetics, which could lead to improved crop yields and disease resistance.
Researchers detected gamma rays from ultra-fast outflows (UFOs) launched by supermassive black holes, providing a basis for understanding their role in regulating black hole growth and galaxy evolution. UFOs create shock waves that accelerate charged particles, influencing the surrounding matter and accelerating star formation.
Researchers at Clemson University developed a bifunctional protein that links natural killer cells to breast cancer tumor cells, triggering the killing of cancer cells. The approach has potential as a new treatment option for triple-negative breast cancer, which is often lethal due to its high heterogeneity and lack of efficient treatm...
A new study from Clemson University identifies specific cell clusters in the brain of fruit flies affected by acute cocaine exposure. The findings show widespread changes in gene expression and distinct differences between males and females, potentially leading to therapeutic development.
Researchers found that the evolutionary distance between a snake's prey species determines venom complexity, not just diet variety. The study uses next-generation sequencing to generate the largest dataset of viperid snakes' proteomes and venom-gland transcriptomes.
Researchers have developed a high-performance thermoelectric compound by intertwining crystalline and amorphous sublattices into a unique crystal-amorphic duality. The new material exhibits excellent thermoelectric performance, paving the way for better electric power in the future.
A new study from Clemson University finds that surveillance-based informative testing (SBIT) can detect and contain COVID-19 outbreaks on campus, reducing cases by 154%. The strategy focused on residential hotspots and was twice as effective as simple random testing.
The research team used laser spectroscopy to define the physics of trapped carriers in organic metal halide perovskite films. By analyzing the photocurrent, they identified defects that reduce efficiency, ultimately leading to increased performance and lower costs for solar cells and other devices.
Researchers are using Drosophila melanogaster fruit flies to explore genetic underpinnings of susceptibility to environmental toxicants and develop precision toxicology. The study aims to identify molecular key event biomarkers in non-mammalian models that predict adverse health outcomes.
A partnership between Clemson University and Nephron Pharmaceuticals Corporation has led to the development of a flexible, open-source benchtop robot that can fill, cap, and seal sterile syringes, increasing productivity and quality control in pharmaceutical manufacturing. This innovation aims to address drug shortages, which have sign...
Researchers found that temperature increases led to a decline in pigmentation in flowers, while aridity increased pigmentation, affecting plant-pollinator interactions. The study used historical climate data and flower color descriptions from museum specimens.
A new center at Clemson University will support research on autonomy-enabled ground vehicles, digital engineering, and virtual prototyping. The project aims to reduce timelines for innovation in the autonomous space and fuel next-wave mobility technologies.
A Clemson University researcher has discovered a new parasitic worm that negatively affects reproduction in the Caribbean spiny lobster. The worm, named Carcinonemertes conanobrieni, is believed to be the first of its kind to infect this species in the Caribbean and western Atlantic Ocean.
Researchers are developing technology to control light's twisting and spinning property to communicate and gather data. The project aims to create channels for light to pass through cloudy air or water, enabling new ways of communication and sensing.
A team of Clemson researchers and international scientists have discovered a new way to measure thermoelectric material properties by using light. This breakthrough could lead to the creation of more efficient thermoelectric materials with higher zT values, which convert heat energy into useful electric energy.
Researchers will investigate the role of Cyp2b genes, human CYP2B6 gene, and environmental toxicants like PFOS in obesity and fatty liver disease. The study aims to understand complex interactions between diet, fat stores, and genetic factors.
Researchers at Clemson University have identified two genetic variations associated with small body size and lance canine, a dental anomaly common in Shetland Sheepdogs. The study found that dogs with these variations are on average one inch shorter and six pounds lighter than unaffected breeds.
Researchers created silicon-based batteries with improved stability and capacity, allowing for faster charging times and increased efficiency. The breakthrough could enable the use of lighter batteries in spacesuits and satellites, reducing mission costs and increasing energy storage capabilities.
Researchers will investigate how changes in microbial diversity affect ecosystem function and health. The study aims to understand the role of functional redundancy in maintaining healthy ecosystems, with a focus on environmental complexity and its impact on soil health.
A CU student collaborated with three research teams to study perovskite nanocrystals, which have numerous applications. The team discovered a phase transition that affects the material's optical properties and has relevance to applications already in use.
Researchers studying cichlid fishes aim to understand genetic mechanisms controlling facial development, which may also apply to humans. The study's findings could help determine if certain medications prescribed for human diseases might cause facial malformations in unborn babies.
Researchers at Clemson University found that climate change will lead to more extreme wet and dry seasons globally. The study predicts that regions already prone to drought and flooding will be disproportionately affected.
Researchers will generate a novel mouse model of TSC, characterize molecular pathways, and test two potential drug therapies to treat SEGAs. Early intervention improves prognosis for children with TSC.