A newly released study by Clemson University scientists provides evidence that disrupting heme production in Toxoplasma gondii could be an effective therapeutic strategy. Researchers found that using herbicides to inhibit the parasite's growth can deny it an essential nutrient, potentially leading to a cure.
Clemson scientist Matthew Koski will advance his research on floral thermoregulatory mechanisms with a 3-year, $455,000 grant. He aims to understand how flowers adapt to climate change by studying their thermal environments in Colorado.
Research suggests that plant species maintain both light and dark pollen due to distinct survival advantages. Lighter morphs have higher seed production ability, while darker morphs produce higher-quality pollen with increased anthocyanidin production, which helps relieve heat stress.
Researchers at Clemson University have discovered that the genetic architecture of life span is context-dependent, with different genes and variants having varying effects on males and females and environmental temperatures. The study uses the Drosophila melanogaster model to provide valuable insights into human aging.
A team of Clemson University researchers has detected a relativistic jet emerging from two colliding galaxies, providing the first photographic proof of this phenomenon. The discovery was made using advanced telescopes and offers insights into the formation of jets in galaxy collisions.
Researchers examined the oral mycobiome, discovering 139 species of fungi that live in human dental plaque, with nine strongly associated with healthy teeth. These beneficial fungi may produce compounds like xylitol, which inhibits cavity-causing bacteria.
A Clemson University team created a double-helical metal-organic framework with unique S-shaped charge transport pathways, enabling it to conduct electricity. The material shows promise as a next-generation semiconductor due to its energy efficiency and temperature tolerance.
Researchers identify over 4,500 novel transcripts in fruit fly genome that regulate networks of genes and contribute to genetic disorders. These findings shed light on the 'dark' portion of human genome, which accounts for 98% of its content.
Researchers developed a fluorescence-based technique to monitor single molecules, accelerating structural biology and potentially aiding in structure-guided drug design. The technique uses FRET to visualize biomolecules with unprecedented spatial and temporal resolution.
A team of Clemson University researchers identified the function of a specific protein in three related parasites that cause African sleeping sickness, Chagas disease, and Leishmaniasis. The discovery provides insights into how these parasites differ from humans, shedding light on potential drug targets.
Dou's research aims to disrupt the parasite's nutrient metabolism, potentially leading to new drug treatments for toxoplasmosis and malaria. The grant will explore the molecular mechanisms of Toxoplasma gondii, a parasite that affects over 40 million people worldwide.
A new framework for integrated geodynamic models is being developed by a team of researchers, including Clemson mathematician Timo Heister. The Advanced Solver for Problems in Earth's Convection (ASPECT) software will simulate processes in the Earth's mantle, providing insights into geological events and tectonic plate movements.
Clemson University professor Joe Kolis is developing new quantum materials using hydrothermal synthesis to make reliable qubits for quantum computing and data storage. By cooling material at lower temperatures, he aims to achieve the necessary magnetic disorder for quantum phenomenon to take over.
Researchers at Clemson University's Center for Human Genetics have identified hundreds of metabolites that may serve as indicators for disease. The study found correlations between genetic variation, metabolite levels, and specific traits, such as stress resistance and aggression.
A team of Clemson University astrophysicists has devised a new measurement of the Hubble Constant, which describes the rate of expansion of the universe. Their analysis of data from orbiting and ground-based telescopes yields a measurement of approximately 67.5 kilometers per second per megaparsec.
Scientists at Clemson University found diverse bacterial communities inside clams that contribute to a balanced ecosystem. The study showed that higher microbial diversity is linked to healthier seagrass environments, with implications for fisheries and lobster farming.
Researchers created a mutated form of DNA repair protein RAD51 to study its critical functions at stalled replication forks. The study found that RAD51's strand exchange activity is not required for fork regression, but is crucial for restarting replication once the obstacle has been removed.
A Clemson University researcher is developing genetically improved perennial grasses that can thrive with less water and serve as a sustainable fuel source. The goal is to create more stress-resistant plants through molecular strategies, including site-specific DNA recombination systems.
A study by Vincent Richards and colleagues found that antibiotic-resistant genes are being transmitted from humans into animal species, including livestock, companion animals, and wildlife. This reverse zoonosis is facilitated by high bacterial genome plasticity, allowing bacteria to adapt quickly to environmental changes.
Researchers will launch two three-year sounding rockets to investigate energy transfer and dissipation during colorful active auroras. The VortEx project aims to measure turbulent processes in the mesosphere, enhancing weather prediction accuracy.
Researchers at Clemson University discovered that salamanders use temperature rather than humidity to anticipate changes in their environment, and harness limb regeneration to minimize the impact of hot temperatures. This adaptation may have implications for other animals and plants, and could provide insights into regenerative medicine.
Researchers at Clemson University examine the effects of feral hogs and elephants on livestock and livelihoods, highlighting the importance of including non-traditional culprits in human-wildlife conflict discussions. They found that these species can cause significant damage to farming infrastructure and affect local communities' perc...
A study by Robin Kowalski found that many people think about advice they would give their younger selves multiple times per week. This mental exercise can help individuals conceptualize their ideal self and overcome regret. The research also revealed that areas of education, self-worth, and relationships are commonly focused on when it...
A study by Clemson researchers found that the Cyp2b gene is associated with obesity and fatty liver disease in male mice, regardless of diet. The discovery suggests that enzymes involved in detoxification may play a role beyond diet and exercise in weight management and metabolic health.
Researchers identify novel genes and networks underlying senescence in maize, a complex trait affected by internal and external factors. Understanding the triggers for senescence in crops like maize can lead to altering plants that can benefit a hungry world, slowing down senescence to keep the plant green longer.
Researchers at Clemson University have made significant progress in understanding the biology of Toxoplasma parasites, a human pathogen with high infection rates. By disrupting a key transporter, they were able to reduce the parasite's infectivity and provide insights into new targets for treatment.
A study by Clemson University Center for Human Genetics reveals that there is extensive genetic variation in the propensity to consume cocaine and methamphetamine, as well as change in this behavior over time. The research uses Drosophila melanogaster fruit flies to assess naturally occurring variation in drug self-administration and f...
Researchers at Clemson University developed a targeted nano therapy that destroyed calcium buildup in arteries without causing side effects. The therapy mimics a human's chronic kidney disease and has the potential to benefit thousands of patients.
Researchers develop TIGER mouse to track information-rich particles in brain, revealing new cell types releasing extracellular vesicles. The study aims to generate an atlas for diagnosing and treating various diseases.
Two Clemson University bioengineers, Will Richardson and Naren Vyavahare, have received NIH grants for new research related to the heart, totaling $4.1 million. They are working on projects aimed at treating cardiac fibrosis and reversing vascular calcification, which could impact millions of patients with cardiovascular disease.
A new study published in JAMA Internal Medicine suggests that price disclosure legislation may not be effective in lowering drug costs. The research found that consumers are less likely to ask about high-priced drugs if they see a clear price disclosure, but this effect is short-lived and can be undermined by coupon programs.
Researchers at Clemson University discover Mojave rattlesnakes have a wider distribution of life-threatening venom types than expected. The study reveals a peculiar variability in the species, with local optima favoring different venom types depending on location.
A Clemson University field study found that tree species grow optimized leaves to compensate for hurricane damage, capturing carbon dioxide at higher rates. However, some trees' lower-quality new leaves may reduce lifespan and energy production.
A team of Clemson University astrophysicists measured the total starlight ever produced throughout the history of the observable universe using data from NASA's Fermi Gamma-ray Space Telescope. They found that this light translates to approximately 4x10^84 photons, which is a vast amount considering most of it comes from distant galaxies.
Researchers at Clemson University are working on a new 3D-printing technique involving rapid laser processing to create protonic ceramic electrolyzer stacks that convert electricity to hydrogen. This technology could lead to cars that go 1,000 miles per fill-up and smartphones that can run for days without recharging. The new technique...
Clemson University's new program aims to recruit doctoral students from underrepresented groups to become professors in chemical engineering. The goal is to create a diverse generation of educators who will serve as role models for women and minority students.
Researchers at Clemson University have discovered a key role for glucose in the parasite's life cycle, potentially leading to new treatments for African sleeping sickness. The study sheds light on how the parasite adapts to its environment and can inform strategies to defuse outbreaks.
Researchers are creating three-dimensional models of blood vessels using pig arteries and human endothelial cells to study fibroblast behavior. This could provide a powerful tool for diabetes basic research and drug screening systems.
Researchers are studying norovirus and Clostridium difficile to determine effective disinfection strategies for cleaning up vomit on soft surfaces. The goal is to control the spread of diseases in long-term care facilities, where outbreaks account for 60% of cases.
Clemson University is developing a customizable virtual reality system, called Enodia, to facilitate collaboration among researchers. The system will enable groups to visualize and share computational simulations, while also enhancing student learning experiences.
The South Carolina Center for Translational Research Improving Musculoskeletal Health brings together scientists from across South Carolina to study and develop new treatments for musculoskeletal disorders. The center will create virtual clinical trials to speed up innovation and improve care.
A Clemson University team has developed a polymer that can heal itself like skin, bringing the technology closer to industrial-scale production. The discovery could significantly reduce production costs for self-healing materials used in various industries.
Facial scans aim to identify Phelan-McDermid syndrome in children by analyzing characteristic flattening and brow shape. This could enable quicker diagnoses and better treatment options for affected families.
The TIME for Robotics program will use virtual reality and personalized learning to teach students about robotics in advanced manufacturing, addressing fears that robots will take jobs. The program aims to attract diverse students and provide a skills gap solution for the industry.
The Center for Human Genetics is conducting research to better understand the genetic causes of rare diseases using a combination of genome-wide association analysis and gene-editing techniques. The team has identified novel transcribed regions that play a crucial role in regulating complex traits.
Homemade steroids have become a widespread issue, with online tools and cryptocurrency facilitating their rapid spread. Clemson researcher Bryan Denham's study examines the impact of these substances on public health, noting that purchasing black-market steroids is similar to buying other illicit substances.
A recent grant from the National Institute of Dental and Craniofacial Research will support a study characterizing the oral microbiome in children with HIV infection. The study aims to understand how HIV affects tooth decay, with potential applications for personalized medicine and improved prevention strategies.
Researchers from Clemson University and Stony Brook University reveal a 3-D structure of a protein fragment that could serve as a drug target in treating stroke patients. The protein, PSD-95, plays a crucial role in maintaining neural connections and facilitating communication, learning, and memory.
The project, which began in 2014 with $5.25 million, aims to ensure safe disposal of nuclear waste for thousands or hundreds of thousands of years. Researchers are using multidisciplinary approaches to study the movement of radionuclides through soil and groundwater.
A standardized protocol for FRET has been established, enabling precise measurement of distances within biomolecules. This breakthrough methodology can overcome size and stability limitations of other structural biology methods, leading to targeted drug development and new research opportunities.