Articles tagged with Measles
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A recent measles case highlights the importance of herd immunity in safeguarding those with compromised immune systems. Despite being fully vaccinated as a child, a Swiss man undergoing leukemia treatment died from severe measles complications.
Researchers studying vampire bats and Morbillivirus aim to understand how viruses persist inside the body and trigger new infections. The project aims to gain fundamental insights into RNA virus persistence and potentially shed light on diseases like SSPE.
A new study by Bocconi scholars links measles resurgence to public health expenditure cuts in Italy. The research found that each 1% reduction in per-capita real public health expenditure corresponds to a 0.5 percentage point decline in MMR vaccination coverage, highlighting the importance of investing in public health.
A 2013 measles outbreak in New York City resulted in 58 confirmed cases, with most unvaccinated individuals affected. The outbreak, triggered by an unvaccinated adolescent's return from London, required a significant public health response, including nearly $400,000 and over 10,000 personnel hours.
Recent outbreaks of measles and mumps have demonstrated the importance of integrated infection prevention response. Studies show that standard patient and visitor messaging, active surveillance, and timely initiation of precautions can effectively control outbreaks. Vaccination rates were also critical in stemming the outbreak, with a ...
Researchers capture images of measles viruses as they emerge from infected cells, gaining insights into the internal organization and potential antiviral strategies. The study reveals a scaffold-like matrix protein acting as a framework for viral assembly.
A portable test has been developed to identify populations at risk of measles and rubella infections in remote areas. The new technology can rapidly test multiple blood samples and is a potentially useful tool for addressing vaccine-preventable diseases in developing countries.
A team of researchers from the University of Toronto has developed a portable, reconfigurable lab-on-a-chip diagnostic platform that can gauge immunity to vaccine-preventable diseases among vulnerable populations. The platform was validated at a refugee camp in Kenya and showed promising results in detecting measles and rubella.
Research presented at ECCMID found that unvaccinated patients accounted for most measles cases, with children under two years old being at higher risk of dying from the disease. The study also highlighted the impact of measles on young populations, with one in 1,000 cases resulting in death.
Having measles in early childhood may predispose individuals to asthma-like symptoms and airway obstruction if they also smoked. Adults with a significant history of asthma and smoking are at a higher risk of developing chronic obstructive pulmonary disease.
A new study in Ghana found that the timing of measles vaccination can significantly impact child survival rates. Measles vaccination after DTP3 increased child survival by 28% within the first year and 18% until age five. The vaccine also showed a stronger beneficial effect on boys compared to girls.
The overall annual incidence of measles in the United States remained low from 2001 to 2015, with most cases reported among unvaccinated individuals. The study suggests that failure to vaccinate may be the main driver of measles transmission, highlighting the importance of maintaining high vaccine coverage.
A 5% drop in MMR vaccinations among children ages 2-11 could triple annual measles cases and increase public health expenditures by $2.1 million per case. The study predicts sharp rises in measles cases if vaccination rates further decline, with potential outbreaks in previously well-vaccinated communities.
A study estimates a three-fold increase in national measles cases in children ages 2 to 11 with just a 5% decline in MMR vaccine coverage, resulting in 150 cases and significant economic losses. Removing non-medical personal belief exemptions for childhood vaccination may mitigate these consequences.
A recent study by Virginia Tech researchers breaks down the ideas driving pro- and anti-vaccination stances, revealing that both sides focus on different concerns and interests. The study's findings suggest that understanding these core concepts can help address public concerns about vaccination safety.
More than half of eligible US travelers fail to receive a pre-trip measles vaccine, despite clinical recommendations. This increases the risk of endemic measles outbreaks in the US. Researchers urge improved provider and traveler knowledge of measles as a travel-related illness and increased vaccination rates.
A study found that 53% of eligible US travelers not receiving the measles, mumps, rubella (MMR) vaccine during pre-travel consultations. Lack of concern about disease risk was the most common reason for non-vaccination. The research team recommends ways to increase vaccination rates among travelers.
Strengthening non-medical vaccine exemption policies can boost vaccination coverage and reduce costs, potentially cutting the risk of measles outbreaks in half. Researchers found that states with weaker policies are 140-190% more likely to experience an outbreak.
Measles can spread quickly in schools, with one infected child potentially infecting up to 27 others on average. High vaccination rates are necessary to prevent transmission, and historical data from a 1904 outbreak supports this finding.
Researchers identified 17 cases of subacute sclerosing panencephalitis (SSPE) in California between 1998 and 2016, most developed symptoms after getting measles as infants before being vaccinated. Vaccinating everyone against measles can prevent SSPE, which is fatal and has no cure.
A modeling study suggests that supplementary vaccination campaigns triggered by measles outbreaks could prevent 28,613 cases over 15 years in high-incidence settings. Vaccination campaigns prompted by serological surveys could prevent more cases, but would need to occur annually in high-incidence settings.
Researchers used satellite imagery and vaccination records to estimate population size and optimize vaccination coverage. The study showed that timing vaccination campaigns with predictable population peaks can improve coverage, especially in areas with limited access to health services.
A systematic review found that the IMCI strategy may lead to slightly fewer deaths among children under five years old. However, its effect on other issues such as illness and quality of care was mixed. The review's findings suggest that while IMCI may be beneficial in certain settings, its cost-effectiveness is uncertain.
A new study analyzing over 4,000 news articles about the 2014-15 Disneyland measles outbreak found that articles with a clear bottom-line message were shared more than twice as much as those without. The research supports 'fuzzy trace theory,' suggesting that communications focusing on the gist will be more compelling.
Researchers analyzed numerous studies and reports to find that unvaccinated individuals comprised a substantial proportion of cases in measles and pertussis outbreaks. Vaccine refusal was associated with an elevated risk for measles and pertussis, even among fully vaccinated individuals.
A recent study found that over half of eligible Americans visiting a travel clinic did not receive the recommended measles vaccine, putting them at risk for infection. Vaccination is also essential for preventing hepatitis A outbreaks in areas with inadequate sanitation, such as Mexico's Tulum resort destination.
A study found nearly 9 million children are susceptible to measles, with nearly 4% of 17-year-olds unvaccinated. The percentage of vaccinated children must remain above 92% to prevent outbreaks.
A study found that youth infected with HIV in utero may not have adequate immunity to measles, mumps, and rubella, even if vaccinated. Those who started antiretroviral therapy early were more likely to have protective antibodies against these diseases.
Researchers at UCLA and University of Illinois found that emphasizing the benefits of vaccination and taking a non-confrontational approach can increase support for vaccination among skeptical parents. A study with 315 adults showed that highlighting the dangers of measles and mumps can substantially increase support for vaccination.
Researchers found that reminding skeptics about the importance of vaccines and the risks associated with not being vaccinated can change their attitudes positively. The study tested three groups of participants and showed that even the most skeptical individuals were influenced by the intervention.
Researchers used genetic sequencing to trace the 2010 measles outbreak, linking it back to two visitors who brought separate genotypes of measles to Vancouver. The D8 and H1 strains spread across the province, resulting in 82 cases of measles.
A study led by Mount Sinai researchers compares flu viruses to the measles virus to identify key genes that can't be changed. This could lead to the development of universal flu vaccines and improved protection against emerging viral threats.
A new study finds that measles virus has rigid surface proteins that can't tolerate mutations, making it less prone to evolution than the flu virus. This difference in protein stability may explain why measles only requires a two-dose vaccine during childhood for lifelong immunity.
A new study reveals that measles vaccination prevents not only measles but also other infectious diseases by damaging the immune system's memory. This finding explains why mass measles vaccinations have driven down mortality rates from other diseases in high-income countries.
A new study reveals that measles can suppress the immune system for up to three years, making children highly vulnerable to other infectious diseases. The research, published in Science, provides epidemiologic evidence that measles attacks immune memory cells, leading to a state of 'immune amnesia'.
A recent measles outbreak in California was likely caused by substandard vaccination compliance, according to a study published in JAMA Pediatrics. The study estimates that vaccination rates among exposed populations may be as low as 50 percent, highlighting the need for herd immunity.
Researchers calculate vaccine coverage among exposed populations in California, Arizona, and Illinois as far below 96-99% necessary for herd immunity. The virus's effective reproduction rate is estimated between 3.2-5.8, emphasizing the importance of vaccination to control outbreaks.
Researchers found that severe disruptions to healthcare systems during the Ebola outbreak led to a significant reduction in measles vaccinations. This could result in an additional 2,000 to 16,000 deaths if a measles epidemic were to occur in affected countries.
A study predicts a rise in measles cases by 100,000 across West Africa due to Ebola-related health system disruptions, resulting in an additional 5,000 measles deaths. The research highlights the need for aggressive regional vaccination programs to counteract the steep downturn in immunization rates.
Researchers estimate that a large measles outbreak in West Africa could infect nearly twice as many people and kill thousands more due to significant decreases in vaccinations for childhood diseases. The Ebola crisis has led to a 45% increase in unvaccinated children, posing a substantial risk to public health.
A study published in Annals of Internal Medicine found that the appropriate use criteria for diagnostic cardiac catheterization may not be reliable for guiding clinical decisions. The researchers evaluated a cohort of 48,336 patients without a history of coronary artery disease and found that obstructive CAD is more likely to be diagno...
A new powdered measles vaccine has been found safe and effective in early human testing, with no clinically relevant side effects reported. The dry powder vaccine was delivered through a puff of air and showed promise as an alternative to traditional injectable vaccines.
A recent review reports on the devastating effects of the Syrian conflict on the healthcare system, including outbreaks of poliomyelitis, measles, and cutaneous leishmaniasis. Vaccination coverage has dropped dramatically, hampering efforts to combat these epidemics.
Researchers highlight gaps in vaccination due to skepticism about childhood vaccines and international travel bringing measles into the country. Experts call for accessible vaccination and research on addressing public concerns about vaccine safety.
The study found that measles death rates were 197 times greater in developing countries than in developed countries, while syphilis death rates were 33-45 times higher. Ebola mortality rates were also significantly higher in developing countries, with 4,447 deaths compared to just two in developed nations.
A study found that measles illness lasts for almost 14 days and causes people to miss nearly 10 days at work or school on average. The analysis also showed that the average number of quality-adjusted life years (QALYs) lost due to measles is 0.019 per patient, equivalent to 6.9 QALYs.
A new report by Princeton University researchers suggests that expanding the age of eligibility for measles vaccination from 12 to 15 months could significantly increase coverage in Africa. The study found that increasing the age range would have the most impact on countries with high rates of unvaccinated children.
A dedicated website for the MMR vaccine is proposed as a simple yet effective way to boost vaccination rates. The study found that providing parents with online information reduces concerns and is more cost-effective than traditional methods like leaflets or face-to-face consultations.
A recent measles outbreak in the US highlights the need for physicians to be familiar with the deadly disease, particularly in return travelers with fever and rash. The author emphasizes the importance of measles vaccination and vigilance in healthcare facilities to prevent further spread.
Children conceived during a severe epidemic show increased resistance to later diseases, a phenomenon known as functional trans-generational effect. This discovery suggests that parents can prepare their children for future diseases, and the underlying mechanism may be linked to an optimized immune response in high-pathogen environments.
Researchers developed a novel antiviral drug to combat measles by reducing virus levels in animals. The drug also prevented animals from dying of the disease and boosted their immunity against the virus. While promising, additional research is needed before its use in humans.
A global consensus statement establishes standardized definitions and measurements for drug-resistant tuberculosis in children. Research findings highlight the importance of colonization pressure as a predictor of healthcare-associated MRSA infections.
The measles virus uses a hairpin-like structure to bind to the MDA5 receptor, preventing it from forming filaments and signaling viral RNA. This interaction allows the virus to evade the immune system's defense mechanisms.
Researchers developed a microneedle technique to dry and stabilize the measles vaccine, showing it remained effective for at least 30 days. The method could provide a new tool for international immunization programs against measles, which killed nearly 140,000 children in 2010.
Babies born to HIV-positive mothers are at risk of measles infection due to impaired maternal antibodies. Early immunization is crucial to prevent measles virus transmission and complications.
The GAVI Alliance has pledged an additional $162 million to control and prevent measles outbreaks in six high-risk countries. The funding will strengthen routine immunisation systems and follows a decision last November to provide over $600 million to tackle rubella through a combined measles-rubella vaccine.
A Mayo Clinic expert and pediatrician refute three immunity-related misconceptions about vaccines, citing a recent review of 1,200 articles that found no autoimmune side effects. The experts also emphasize the risk of illness and death from under-vaccination, including whooping cough and measles.
Global measles mortality decreased by 74% from 535,300 deaths in 2000 to 139,300 in 2010. Despite this progress, India and Africa remain major concerns due to low vaccine coverage. The authors suggest intensified control measures are needed to achieve mortality reduction targets.
A new model based on game theory and social learning can predict the patterns of vaccine scares, explaining why vaccine uptake takes time to recover after a scare. The model highlights the interplay between disease dynamics and vaccination behavior, suggesting that herd immunity can lead to complacency among unvaccinated individuals.
A study by Kaiser Permanente found no increased risk of febrile seizures among 4-6 year olds after measles-containing vaccine administration. The research analyzed over 86,750 children and found that separate MMR plus V vaccines also did not increase the risk of febrile seizures in this age group.