Researchers have identified a specific cell-stress signaling pathway that links optic nerve injury to irreversible vision loss. The unfolded protein response (UPR) pathway was found to be activated in response to axonal damage, leading to pro-cell-death effects.
Researchers developed a tool to measure outcomes of brachial plexus surgery, which is currently inconsistent and difficult to compare. The new tool aims to standardize reporting, helping clinicians advance the science and improve patient care.
Researchers discovered a way to boost nerve growth in peripheral nervous system, offering potential treatments for diabetes and traumatic injuries. Blocking PTEN molecular brake increased nerve outgrowth, providing hope for recovery from nerve damage
A mouse model of neuropathic pain showed that immune cells producing opioids reduced symptoms, suggesting a novel approach for pain relief. Selectively targeting opioid-containing immune cells may provide natural pain relief and offer a new treatment option.
Using a three-dimensional image-guided system to help place screws in the spine results in safe and accurate surgery with decreased nerve injuries and misplaced screws compared to traditional operations.
A new study from Michigan Medicine reveals that obese patients have a higher risk of post-operative complications, including heart attack, wound infection, nerve injury, and urinary tract infection. The study found that morbidly obese patients had a death rate nearly twice as high as non-obese patients.
Wound botulism is a potentially fatal illness caused by Clostridium botulinum spores contaminating wounds. A case study published in PLoS Medicine reports a man's full recovery after prompt diagnosis and treatment with ventilator support and botulinum antitoxin.
Persistent post-operative pain affects 10-15% of individuals after common operations. Surgical techniques like careful dissection and minimally invasive methods can reduce nerve damage and associated pain. Surgeons must be aware of these techniques to improve patient outcomes.
Peroneal nerve injuries are common in traumatic knee dislocations and require precise knowledge for surgical intervention. Sonography accurately identifies nerve injuries and their extent, enabling optimal therapy planning.
A study by Temple University researchers found that nerve injuries caused by repetitive strain can lead to chronic pain and degenerative problems, with cytokines playing a key role. Cytokines may affect employees' psychosocial responses, leading to 'sick-worker' syndrome, characterized by slacking off work and low-grade depression.
Researchers discovered a gene, Hsp27, that protects mature nerve cells from death following injury. Delivering this gene via therapy may lead to new treatments for neurodegenerative diseases and nerve injuries.
A Mayo Clinic study found that youth football injuries are rare and often mild. The risk of injury increased with the player's age and level of play, but not with body weight. Most injuries were contusions, while fractures involving the ankle growth plate were more common in higher grades.
Research reveals that specific growth factors can speed up muscle regeneration and quicken healing in animal models. The findings hold promise for treating various types of muscle injuries in humans, including those affecting athletes who risk ending their careers due to disabilities caused by muscle injuries.