Articles tagged with Obesity
A recent Yale study found that high-fat diets stimulate hypothalamic inflammation, leading to changes in microglial cells and regulating energy homeostasis. The research suggests a neurological mechanism controlling food intake, with potential implications for obesity and diseases like Alzheimer's.
A large cohort study found that obesity is consistently associated with a greater burden of symptoms and experiences of distress among patients with breast or prostate cancer. Among patients with colon cancer, significant symptoms and distress were observed regardless of weight, suggesting alternative factors at play.
Researchers at U of M Medical School have discovered a new mechanism that could help treat obesity. The team found critical mutations in molecules implicated in obesity and diabetes, suggesting a possible therapeutic approach to human disease.
A study published by Cleveland Clinic shows that weight-loss surgery is associated with a lower risk of death and major adverse cardiovascular events than usual medical care. Patients who underwent surgery also had better diabetes control, used fewer medications, and lost more weight.
A mouse study found that exercise prior to and during pregnancy restores tissues in the body, improving blood sugar levels and lowering the risk of long-term health problems. The researchers suggest that an active lifestyle is crucial when planning pregnancy.
A new study finds that waist size, not overall obesity, is a significant predictor of coronary artery disease in postmenopausal women. The study, published in Menopause, found no association between body mass index and obstructive cardiovascular disease.
A new study finds that excess body fat increases the risk of depression, with a 17% higher probability for every ten kilograms of extra weight. The study suggests that psychological consequences of being overweight or obese drive this increased risk, rather than biological effects.
A new study at Binghamton University reveals that obesity is connected to a weaker response to taste. Researchers found that obese rats showed smaller and less responsive taste reactions compared to lean rats.
Researchers at Rutgers University have found that brown fat can filter and remove branched-chain amino acids (BCAAs) from the blood, which are linked to diabetes and obesity. The study suggests that environmental factors such as cold temperatures or spicy foods may be able to control BCAA uptake by brown fat.
Researchers discovered a connection between high-fat diets and insulin resistance through gut bacteria, specifically the protein IgA produced by B cells in the gut. A high fat diet weakens the gut immune system, leading to inflammation and worsening blood sugar levels.
A new study published in the Journal of Clinical Investigation reveals a previously unknown gut-brain connection that plays a key role in obesity caused by overeating. The research found that increased levels of gastric inhibitory polypeptide (GIP) in the gut inhibit the action of leptin, leading to weight gain.
A proof of concept study uses an 'obesity simulation suit' to teach medical students about obesity and uncover their prejudices. The results show that nearly two-thirds of medical students found the suit realistic, but also harbored more negative attitudes towards obesity than teachers or patients.
Research finds heart disease and stroke mortality rates are barely declining or increasing in 12 high-income countries since 2000. Obesity levels may be a significant contributor to the slowdown.
The American Thoracic Society has published a clinical guideline on the evaluation and management of obesity hypoventilation syndrome (OHS), a breathing disorder affecting obese individuals. The guideline aims to improve early recognition and effective treatment, reducing morbidity and mortality.
A new study has established the strongest evidence yet of a causal relationship between obesity and various serious conditions. The research analyzed data from the UK Biobank to assess associations between body mass index (BMI) and disease outcomes in 337,536 people.
A study of 18,424 Han Chinese adults found that regular jogging and other exercises like mountain climbing and yoga reduce BMI in individuals predisposed to obesity. These findings suggest that genetics are not destiny and that exercise can help mitigate genetic effects on obesity.
A new study found that people with obesity experience higher levels of initial taste perception and greater satisfaction from food compared to those with normal weight. This difference in taste perception may lead to increased food consumption among individuals with obesity, contributing to their higher caloric intake.
A recent study from the Rudd Center for Food Policy and Obesity found that weight stigma in men is associated with harmful health consequences, including depressive symptoms and dieting behaviors. Men who experienced or internalized weight stigma had higher rates of binge eating and lower self-rated health.
A recent study found that university students who used their smartphones for five or more hours a day had a 43% increased risk of obesity. This prolonged cell phone use was associated with decreased physical activity and unhealthy lifestyle habits, including consuming sugary drinks and fast food.
A new study reveals that T follicular helper cells shield mice from obesity by promoting IgA antibody production, which suppresses lipid absorption. This discovery highlights the immune system's role in regulating the gut microbiome and offers potential for novel treatments against metabolic diseases.
A computer-simulated study suggests that standard solid food feeding guides from hospitals and baby-formula makers may not provide accurate recommendations for infants. Following these guidelines can lead to overweight infants as early as 9-11 months old, with the Similac guide producing the healthiest results.
Researchers at University of Utah Health identified a specific class of gut bacteria called Clostridia that prevents mice from becoming obese. Giving these microbes back to mice with an impaired immune system allows them to stay slim, suggesting a potential therapeutic approach for humans.
A new study has filled gaps in knowledge on weight loss experiences for minority groups with type 2 diabetes. Researchers found that tailoring interventions to individual needs, including behavioral strategies and meal replacement use, can improve health outcomes among African Americans and Hispanics with the condition.
A study published by the American Academy of Neurology found that having a higher BMI and bigger waistline in the 60s is associated with greater signs of brain aging. This can lead to accelerated brain thinning, which is tied to an increased risk of Alzheimer's disease.
A study of nearly 157,000 postmenopausal women found those with normal weight and high abdominal fat had a higher risk of death compared to their counterparts with no central obesity. The findings highlight the importance of considering body shape and fat distribution in addition to BMI for obesity prevention.
A study published in Neurology found that having a bigger waistline and high BMI in the 60s is associated with greater signs of brain aging. The study suggests that obesity accelerates brain aging, which can increase the risk of Alzheimer's disease by at least a decade.
Researchers found that meal timing strategies like eTRF lower hunger hormone levels and improve metabolic flexibility, while also increasing fat-burning. The study suggests that these strategies may be more effective than previous research on improving metabolic health.
A study published in JAMA Network Open found that women with normal weight but high waist circumference were 31% more likely to die from cardiovascular disease and obesity-related cancer. Waist size is a forgotten factor in defining obesity, and its inclusion could lead to better risk evaluation and intervention programs.
A recent study published in The FASEB Journal explored the potential of SIRT6 to protect the heart from developing diabetic cardiomyopathy. Researchers found that SIRT6 over-expression can prevent the development of obesity and cardiomyopathy under conditions of excess nutrition.
Obesity experts argue that it should be recognized as a chronic disease due to its strong biological influence and severe complications. They believe this approach can help reduce stigma and discrimination, but critics caution that labeling obesity as a disease may not lead to better outcomes for individuals or society.
A new study published in PLOS ONE found that spaying or neutering large-breed dogs can lead to a higher risk of obesity and nontraumatic orthopedic injuries. Dogs spayed or neutered before 6 months of age were at a significantly greater risk of sustaining these injuries.
Researchers identified a molecular mechanism that may be contributing to the global obesity epidemic. The study found that a protein called RAGE on the surface of fat cells can block fat burning when stressed, leading to weight gain. Removing RAGE from fat cells reduced weight gain in mice fed a high-fat diet.
A study by Clemson researchers found that the Cyp2b gene is associated with obesity and fatty liver disease in male mice, regardless of diet. The discovery suggests that enzymes involved in detoxification may play a role beyond diet and exercise in weight management and metabolic health.
Patients with Type 1 diabetes who are obese often face denied pancreas transplantation due to high infection risks. However, robotic pancreas transplantation has shown promising results, reducing blood loss and surgical complications while improving patient outcomes.
A new study by Massachusetts General Hospital found that labeling food choices with simple 'traffic-light' symbols reduced the number of calories purchased by employees in the hospital cafeteria. The intervention was associated with a sustained reduction in calories over two years, with estimated weight loss ranging from 1-2 kg per year.
A biomedical scientist is studying how the body's cannabis-like molecules affect feeding behavior and contribute to obesity. The research aims to identify novel therapeutic strategies for safely treating obesity and related metabolic disorders, which are currently lacking reliable options.
A UTSA professor is designing a novel protein blocker to inhibit the activity of P450 8B1, a human enzyme linked to bad cholesterol and obesity. The breakthrough aims to fight rising obesity rates and related health issues like high blood pressure and strokes.
Researchers suggest that strengthening muscles, rather than losing fat, may be a better way to protect against weight-related health risks like diabetes and cardiovascular disease. Muscle health is linked to metabolic function, insulin sensitivity, and glucose uptake, making it a potential indicator of overall health.
A study led by Dr. Stephanie Kullmann found that exercise improves brain function in overweight and obese individuals by normalizing brain functions important for metabolism and increasing regional blood flow in areas of the brain dependent on dopamine. Participants also reported improvements in mood and executive function.
Researchers found that intranasal insulin delivery improves performance on memory tasks and increases brain connectivity in adolescents with high BMI. The study suggests that obesity-related cognitive impairment can be reversed by intranasal insulin.
Two metabolic pathways, NAD+–SIRT1 and FAD–LSD1, play a role in regulating energy metabolism and tissue development. These pathways are controlled by dietary vitamins and hormones, leading to the induction of fat accumulation and obesity.
A recent study of 375 adults found that exercising at a consistent time of day was associated with higher physical activity levels. The research suggests promoting daily routine consistency may be essential for achieving and sustaining weight loss.
Researchers found that combining aerobic exercise and resistance training preserves muscle mass in obese older adults. The study showed increased muscle protein synthesis and improved muscle quality compared to control groups.
A substantial increase in BMI has been observed since the 1960s, with both genetically predisposed and non-predisposed individuals experiencing weight gain. The study's findings suggest that genetic predisposition interacts with an increasingly obesogenic environment to contribute to higher BMI in recent decades.
Researchers found that mice lacking group-2 innate lymphoid cells in the small intestine prevented obesity after eating a high-fat diet. Conversely, reintroducing these cells led to obesity symptoms. The study suggests targeting small intestine ILC2s could be an effective obesity treatment approach.
About 30% of nursing home residents are obese, requiring special care and accommodations such as wheelchairs and lifts. A five-year study will identify best practices in caring for obese residents and develop a toolkit to help nursing homes meet their needs.
A new study in mice reveals that diet-induced obesity re-wires the brain's natural brakes on food intake, leading to pathological eating behaviors. The research identifies a specific class of cells that normally suppress feeding to prevent overeating, but are altered in obese mice, promoting excessive food consumption.
A large study found that people with a high body mass index (BMI) or who gain weight as they get older may have a lower risk of amyotrophic lateral sclerosis (ALS). The researchers also found that participants who gained the most weight had a 37-percent lower risk of ALS than those who didn't gain weight or lost weight.
A multidisciplinary team at LSU Health is using two new research techniques to study the link between obesity and breast cancer. They will observe breast tumor development in real-time using a biomimetic tissue-engineered 3D culture system, and analyze the extracellular matrix of breast cancer tumors using decellularization technique.
The Obesity Medicine Education Collaborative developed the first set of obesity-focused competencies to improve obesity medicine education for physicians and advanced healthcare providers. The 32 competencies aim to introduce obesity medicine education early and ensure adequate training for treating obesity.
A 10% tax on sugary drinks has cut purchases and consumption by an average of 10%, according to a major review. The review analyzed data from four US cities and two European regions, finding that taxes resulted in decreased sales and purchasing of taxed beverages.
The Obesity Society has developed two new resources to improve obesity medicine education in medical schools and advanced healthcare providers. The resources include the first set of competencies for caring for patients with obesity and a proposed standard of care for adults with obesity, aimed at enhancing patient care.
A new study found that a home-based high-intensity interval training (Home-HIT) programme is as effective as supervised, lab-based cycling or Government-recommended moderate intensity exercise for obese individuals. Home-HIT reduces barriers to exercise, such as time and cost, making it a more attainable exercise goal.
A Yale-led study reveals the mechanisms by which leptin increases appetite in response to low energy levels. The research found that reductions in plasma leptin concentrations stimulate food intake through a chain of events involving the brain, endocrine system, and AgRP neurons.
A study by Brazilian scientists shows that moderate strength and weight training can reduce liver fat and improve blood sugar control in obese and diabetic individuals. The exercise protocol reduced local fat in the liver and improved cellular insulin signaling, even before significant weight loss occurred.
A UC Riverside-led study reveals that overactive endocannabinoid signaling in the gut blocks satiation signals, leading to overeating and obesity. Researchers hope to develop drugs targeting these receptors to address obesity.
An observational study of nearly 44,000 women found that exposure to artificial light at night while sleeping was associated with measures of obesity at baseline and follow-up. Reducing exposure to artificial light at night could be considered in obesity prevention interventions.
Research finds that cutting off lights at bedtime could reduce women's chances of becoming obese. The study analyzed data from 43,722 women and found a link between artificial light exposure and increased weight gain.
Studies found many prenatal supplements contain too much folic acid and often have higher nutrient content than labeled, while vitamin D supplementation improves babies' growth. A healthier diet before pregnancy may lower the risk of preeclampsia, and obesity severity affects weight gain and baby size during pregnancy
A new study published in Alimentary Pharmacology & Therapeutics found that gastric bypass surgery improves acid reflux symptoms in most patients shortly after surgery. However, symptoms often return within 2 years, especially in women and older individuals with other medical problems.