Articles tagged with Obesity
A study published in JAMA Dermatology found that bariatric surgery significantly reduces the risk of malignant melanoma and other skin cancers in severely obese individuals. The study, which followed over 2,000 participants, showed a 57% decrease in malignant melanoma risk for those who underwent bariatric surgery.
Researchers found that patients with high body mass index (BMI) responded better to atezolizumab, a common immunotherapy treatment for non-small-cell lung cancer (NSCLC). This unexpected result may lead to further investigation into the potential link between BMI and inflammation in cancer treatment outcomes.
A review article published in The New England Journal of Medicine suggests that intermittent fasting can improve blood sugar regulation, increase resistance to stress, and suppress inflammation. Studies have shown that this adaptation may trigger a slower metabolic process, which can lead to weight loss and reduced belly fat.
A recent study found that obesity is a significant risk factor for cardiotoxicity in breast cancer patients treated with chemotherapy, particularly those receiving anthracyclines and trastuzumab. The study suggests that overweight and obese individuals may benefit from careful cardiac screening and follow-up during treatment.
Researchers at Helmholtz Munich have created a technique called Mid-infraRed Optoacoustic Microscopy (MiROM) that provides real-time images of biomolecules in living cells without the need for labels or contrast agents. This method offers novel insights into metabolic processes and can be used to study the effects of different diets on...
Research suggests that longer exposure to obesity and earlier development of obesity are linked to an increased risk of type 2 diabetes. Women who experienced rapid weight gain from young adulthood had a higher risk of developing the disease compared to those who remained stable.
People with obesity produce more carbon dioxide due to higher metabolism and food consumption, contributing to 1.6% of global man-made emissions. Managing obesity can favorably affect the environment, with potential implications for healthcare and environmental policies.
The Obesity Medicine Association is launching local chapters in 12 cities/states to educate and empower healthcare providers. The chapters will provide a gathering space for clinicians to learn about the latest treatment options and share knowledge.
A new study suggests that glutamine supplementation could help people with obesity reduce inflammation of fat tissue and reduce fat mass. Glutamine levels were found to alter gene expression in several different cell types, leading to anti-inflammatory effects on white blood cells and T-cells.
By 2030, nearly half of US adults are expected to have obesity, and more than a quarter will have severe obesity. The study predicts that several states will have obesity rates close to 60%, with severe obesity becoming the most common BMI category among low-income adults.
A large study of over 1 million women found that obesity in midlife increases the risk of dementia later in life, while poor diet and lack of exercise are not. The study also revealed short-term associations between these factors and dementia risk may be due to early symptoms of dementia.
A study led by ISGlobal found that living near green spaces reduced the risk of excess weight and obesity in women. Genetic predisposition and gene-environment interactions also played a role in the association.
The global food system has led to an intersection of undernutrition and overweight in low- and middle-income countries. More than a third of these countries face the double burden of high levels of both, primarily due to changes in food systems and increasing availability of ultra-processed foods.
Researchers found that labelling food with the amount and type of exercise needed to burn off its calories can lead to a reduction in daily calorie intake. PACE (Physical Activity Calorie Equivalent) labelling was associated with an average reduction of 65 fewer calories per meal, and up to 200 calories less per day.
A study presented at EuroEcho 2019 found that bariatric surgery significantly improved subclinical heart function, reversing abnormal heart structure and function in obese individuals. The surgery also led to improvements in type 2 diabetes, hypertension, and dyslipidaemia, resulting in a lower risk of cardiovascular disease.
A study of over 3,300 children reveals Finnish kids excel in motor skills, with significant differences found between countries. Portuguese children have weak motor skills, especially between ages 6-10, while Finland and Belgium outperform in this area.
A recent study found that resistance exercise, alone or combined with aerobic exercise, effectively reduces weight loss-induced decreases in hip bone density. The study suggests that incorporating resistance exercise into weight loss regimens can help protect against bone loss in older adults with obesity.
Patients with excess weight experience predominantly negative interactions during clinical consultations, often feeling judged and dismissively told to lose weight. Supportive language and approach are essential in these conversations to promote a positive experience and encourage healthy behavior change.
A recent study examining the potential link between traffic-related air pollution and obesity found a significant association with higher BMI in Mexican American women. In contrast, exposure to higher traffic pollution was linked to lower BMI in men, but not an increase.
A new study found that Class I drug treatment showed increased rates of AFib reoccurrence in obese patients compared to non-obese patients. The study suggests that obesity hinders the effectiveness of these medications, which could impact ethnic minority populations who are more likely to experience obesity and have poorer outcomes.
A Scripps Research study found that blocking the kappa opioid receptor while on a restricted-calorie diet resulted in significant weight reductions. Blocking this receptor may be a potential treatment approach for obesity.
Scientists at University of Utah Health have discovered new genetic elements that could help control obesity and metabolic disorders. Hibernating mammals have evolved short non-coding DNA snippets near genes linked to obesity in humans.
Research found that obesity and smoking can lead to slower fracture healing and higher disability in patients with wrist fractures. However, the study also showed that clinical and radiographic outcomes are achievable with surgery for displaced wrist fractures in obese and smoking patients.
Researchers discovered that an extract from ginseng can induce Enterococcus faecalis, which produces myristoleic acid to activate brown adipose tissue and reduce adiposity. Increasing BAT activity could be a novel therapeutic approach for obesity and related diseases.
Scientists at Scripps Research Institute have discovered a little-known protein that plays a crucial role in managing glucose and insulin levels in the body. The protein, PGRMC2, acts as a chaperone for heme, a molecule essential for cellular processes, and its absence is linked to obesity and metabolic diseases.
Researchers at the University of Illinois Chicago report that robotic kidney transplants produce similar one- and three-year patient survival rates as those seen among nonobese patients. The study included over 230 robotic-assisted kidney transplants in patients with obesity, achieving dramatic reductions in post-surgery wound infections.
A research team found that consuming cholera toxin B stimulates health-protective immune responses that counteract age-associated obesity. The study used animal models and found that the toxin helped restore immune homeostasis and reduce inflammation, leading to leaner physiques and improved health outcomes.
Researchers from Massachusetts General Hospital found that uninfected adolescents and young adults born to mothers with HIV have a fourfold increased risk of obesity and asthma-like symptoms. The study revealed metabolic and immune consequences of in utero HIV exposure.
A study published in JAMA Network Open found that 86% of diet trials amended their primary outcomes. This discrepancy raises questions about the rigor of these trials and potential biases. Researchers are calling for more investment in rigorous diet research to pin down the effects of dietary changes.
Researchers found that bariatric weight-loss surgery can release toxic chemicals like PCBs and organochlorine pesticides stored in fat into the bloodstream. Patients born before 1976 showed higher levels of these compounds due to greater exposure to environmental toxins.
A recent study led by Tulane researchers reveals that while more adults are attempting weight loss, the average BMI of Americans continues to increase. Researchers found that only a minority of those who tried to lose weight achieved success, highlighting the need for effective weight loss strategies.
Preliminary research suggests that weight-reduction surgery can help reduce the risk of stroke and death in obese patients. The study found that participants who underwent bariatric surgery were 69% less likely to experience a clot-caused stroke and 68% less likely to die during follow-up compared to those who did not receive surgery.
Pregnant women with low vitamin B12 levels experience increased fat production and reduced breakdown, predisposing them to obesity. A recent study found that vitamin B12 deficiency impairs fat cell metabolism, leading to increased inflammation and impaired metabolic function.
A new study reveals that bariatric surgery can lead to successful weight loss and better diabetes control in older adults. After two years, the patients had lost an average of 24% of their body weight and seen a significant reduction in HbA1c levels. The study suggests that age alone should not be considered a contraindication to baria...
A new study found that bariatric surgery significantly reduces the risk of cancer in patients who lose at least 20% of their body weight. The risk was reduced by 50% compared to those who did not experience significant weight loss after surgery.
Women with a genetic predisposition for breast cancer were 2.5 times more likely to develop malignancy without weight-loss surgery, but the risk was significantly reduced after bariatric or weight-loss surgery. The study found that weight-loss surgery cut the overall risk of developing cancers linked to obesity by 20 percent.
A large-scale study found that high waist circumference is associated with an elevated risk of obesity-related dementia in older populations. Participants with a waist circumference of 90cm or more had a significantly increased risk of dementia after adjusting for other factors.
Researchers developed a definition of hyper-palatable foods using nutrition software and applied it to 7,757 food items. Most US foods (62%) met the criteria for enhanced palatability, with high fat and sodium being the most common factor. The study aims to inform policymakers on how to address hyper-palatable foods in children's diets.
A new study found that intensive lifestyle interventions, combined with medication, produce clinically significant improvements in quality of life outcomes for obese patients. Participants who received both liraglutide and behavioral therapy achieved more meaningful weight-related quality of life improvements compared to those who rece...
A new calculator developed by Cleveland Clinic researchers can estimate a patient's risk of developing major health complications over the next 10 years depending on their treatment choice. The calculator provides personalized evidence-based information on heart disease, stroke, and other risks with usual care versus surgical treatment.
Patients who underwent metabolic surgery had a lower risk of developing systolic heart failure and dying from recurrent myocardial infarction compared to those without surgery. The study found significant cardiovascular benefits of metabolic surgery, emphasizing its potential as part of the treatment plan for patients with severe obesi...
A new study presents evidence that patients with a BMI of 30 or higher may achieve greater health benefits from weight loss surgery than previously thought. Researchers found that these patients are more likely to reach a healthy weight, have improved quality of life and resolve type 2 diabetes.
A new web-based calculator predicts a patient's likelihood of dying from complications or experiencing serious health issues due to type 2 diabetes and obesity, whether they undergo metabolic surgery or continue with standard medical therapy. The Individualized Diabetes Complication Risk Calculator provides a personalized risk score ba...
A Veterans Affairs study found that bariatric surgery did not result in lower healthcare costs for nearly 10,000 veterans over a 10-year period. Despite the benefits of weight loss and improved health, patients required additional treatment for short-term complications, such as nausea and dehydration, which increased costs.
Researchers have discovered that avocatin B, found only in avocados, counters incomplete oxidation in skeletal muscle and the pancreas, reducing insulin resistance. The study found significant weight loss and improved insulin sensitivity in mice fed with a high-fat diet supplemented with AvoB.
The study found that weight-loss surgery significantly reduced healthcare expenditures for veterans with severe obesity over a period of up to 10 years. The observed decrease in medical costs was attributed to improved health outcomes and reduced need for ongoing medical interventions.
A recent study found that people with obesity share similar personality profiles with those with addictive behaviors, including uncontrolled eating. This suggests that obesity treatments may benefit from adopting methods used in addiction recovery to improve self-control.
A randomized, controlled feeding study found that eating one avocado a day was associated with lower levels of LDL (specifically small, dense LDL particles) and oxidized LDL in adults with overweight or obesity. Avocados also helped reduce oxidized LDL particles and increased antioxidant lutein levels.
China's obesity rates have nearly tripled over the past decade, reaching 14% for general obesity and 32.4% for abdominal obesity among adults. A cluster of high obesity prevalence was identified in the Beijing-Tianjin-Hebei region, highlighting the need for targeted interventions to address this growing health concern.
A study from King's College London found that sugary soft drinks are associated with both obesity and tooth wear among adults. The acidic nature of these drinks leads to tooth erosion, particularly in obese patients. This highlights the importance of monitoring calorie intake through acidic sugar-sweetened drinks.
A study published in PLOS Genetics found that obesity is associated with a higher risk of type 2 diabetes in women and chronic obstructive pulmonary disease and chronic kidney disease in men. The researchers analyzed data from over 423,000 participants and identified distinct patterns of disease association for each sex.
Researchers link high glucose levels to impaired circadian clock function in obesity, which may drive cardiovascular disease. Intermittent fasting and clock repair drugs show promise in restoring normal circadian rhythms and improving cardiovascular health.
A study found that plant-based diets and Mediterranean diets are associated with high levels of friendly gut bacteria, aiding nutrient production and SCFA energy for cells lining the colon. Plant protein helps biosynthesis of vitamins and amino acids.
A recent study published in the European Respiratory Journal has provided evidence that fatty tissue builds up in the airway walls of individuals who are overweight or obese. This accumulation alters the normal structure of the airways and leads to inflammation in the lungs, which may contribute to increased asthma symptoms.
A recent study published in The BMJ found that weight gain from young adulthood to middle age increases the risk of premature death. Maintaining a normal weight throughout adulthood is crucial for reducing this risk, especially preventing weight gain during early adulthood.
Researchers have discovered a causal link between high blood pressure, obesity, and reduced lifespan in a massive genetic analysis of 700,000 individuals. By analyzing polygenic risk scores, the team identified blood pressure and obesity as key drivers of human longevity.
A Norwegian study found that being overweight before age 40 significantly increases the risk of several types of cancer, including endometrial cancer by 70%. Obesity is also linked to an increased risk of postmenopausal breast, renal-cell and colon cancers.
A new medical device called Sleeveballoon has been tested in rodents and produced impressive results on body weight, fatty liver, and diabetes control. The device reduces food intake by 60% and blood glucose levels by 65%, mimicking the effects of traditional bariatric surgery with a minimally invasive approach.
A University of Waterloo study found that Grindr's anonymous nature and lack of size inclusivity contribute to weight stigma among gay men, leading to body dissatisfaction and sexual objectification. Protective factors like positive self-esteem and social support can mitigate these effects.
New research reveals that maternal obesity accelerates the aging process in offspring, leading to increased susceptibility to diabetes and heart disease. Exercise by the offspring can help mitigate these risks, highlighting the importance of early life conditions on future health outcomes.