Articles tagged with Obesity
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Researchers found that intranasal insulin delivery improves performance on memory tasks and increases brain connectivity in adolescents with high BMI. The study suggests that obesity-related cognitive impairment can be reversed by intranasal insulin.
Two metabolic pathways, NAD+–SIRT1 and FAD–LSD1, play a role in regulating energy metabolism and tissue development. These pathways are controlled by dietary vitamins and hormones, leading to the induction of fat accumulation and obesity.
A recent study of 375 adults found that exercising at a consistent time of day was associated with higher physical activity levels. The research suggests promoting daily routine consistency may be essential for achieving and sustaining weight loss.
Researchers found that combining aerobic exercise and resistance training preserves muscle mass in obese older adults. The study showed increased muscle protein synthesis and improved muscle quality compared to control groups.
A substantial increase in BMI has been observed since the 1960s, with both genetically predisposed and non-predisposed individuals experiencing weight gain. The study's findings suggest that genetic predisposition interacts with an increasingly obesogenic environment to contribute to higher BMI in recent decades.
Researchers found that mice lacking group-2 innate lymphoid cells in the small intestine prevented obesity after eating a high-fat diet. Conversely, reintroducing these cells led to obesity symptoms. The study suggests targeting small intestine ILC2s could be an effective obesity treatment approach.
About 30% of nursing home residents are obese, requiring special care and accommodations such as wheelchairs and lifts. A five-year study will identify best practices in caring for obese residents and develop a toolkit to help nursing homes meet their needs.
A new study in mice reveals that diet-induced obesity re-wires the brain's natural brakes on food intake, leading to pathological eating behaviors. The research identifies a specific class of cells that normally suppress feeding to prevent overeating, but are altered in obese mice, promoting excessive food consumption.
A large study found that people with a high body mass index (BMI) or who gain weight as they get older may have a lower risk of amyotrophic lateral sclerosis (ALS). The researchers also found that participants who gained the most weight had a 37-percent lower risk of ALS than those who didn't gain weight or lost weight.
A multidisciplinary team at LSU Health is using two new research techniques to study the link between obesity and breast cancer. They will observe breast tumor development in real-time using a biomimetic tissue-engineered 3D culture system, and analyze the extracellular matrix of breast cancer tumors using decellularization technique.
The Obesity Medicine Education Collaborative developed the first set of obesity-focused competencies to improve obesity medicine education for physicians and advanced healthcare providers. The 32 competencies aim to introduce obesity medicine education early and ensure adequate training for treating obesity.
A 10% tax on sugary drinks has cut purchases and consumption by an average of 10%, according to a major review. The review analyzed data from four US cities and two European regions, finding that taxes resulted in decreased sales and purchasing of taxed beverages.
The Obesity Society has developed two new resources to improve obesity medicine education in medical schools and advanced healthcare providers. The resources include the first set of competencies for caring for patients with obesity and a proposed standard of care for adults with obesity, aimed at enhancing patient care.
A new study found that a home-based high-intensity interval training (Home-HIT) programme is as effective as supervised, lab-based cycling or Government-recommended moderate intensity exercise for obese individuals. Home-HIT reduces barriers to exercise, such as time and cost, making it a more attainable exercise goal.
A Yale-led study reveals the mechanisms by which leptin increases appetite in response to low energy levels. The research found that reductions in plasma leptin concentrations stimulate food intake through a chain of events involving the brain, endocrine system, and AgRP neurons.
A study by Brazilian scientists shows that moderate strength and weight training can reduce liver fat and improve blood sugar control in obese and diabetic individuals. The exercise protocol reduced local fat in the liver and improved cellular insulin signaling, even before significant weight loss occurred.
A UC Riverside-led study reveals that overactive endocannabinoid signaling in the gut blocks satiation signals, leading to overeating and obesity. Researchers hope to develop drugs targeting these receptors to address obesity.
An observational study of nearly 44,000 women found that exposure to artificial light at night while sleeping was associated with measures of obesity at baseline and follow-up. Reducing exposure to artificial light at night could be considered in obesity prevention interventions.
Research finds that cutting off lights at bedtime could reduce women's chances of becoming obese. The study analyzed data from 43,722 women and found a link between artificial light exposure and increased weight gain.
Studies found many prenatal supplements contain too much folic acid and often have higher nutrient content than labeled, while vitamin D supplementation improves babies' growth. A healthier diet before pregnancy may lower the risk of preeclampsia, and obesity severity affects weight gain and baby size during pregnancy
A new study published in Alimentary Pharmacology & Therapeutics found that gastric bypass surgery improves acid reflux symptoms in most patients shortly after surgery. However, symptoms often return within 2 years, especially in women and older individuals with other medical problems.
A recent study by I.R.C.C.S. Neuromed found that obese patients with multiple sclerosis have a greater risk of presenting higher EDSS scores and experiencing increased central inflammation. The research suggests that excessive body weight and altered lipid profiles may be associated with worsened clinical expression of the disease.
New research from Marshall University establishes adipocyte Na/K-ATPase signaling worsens obesity and related diseases, including neurodegeneration and NASH. Targeting the signaling pathway with NaKtide improves metabolic profile and demonstrates therapeutic potential.
A 10-week interval training program improved body composition in older adults with belly fat, with participants losing nearly two pounds of fat mass and gaining lean body weight. The exercise program showed significant reductions in belly fat for men but not women, highlighting the need for further research.
Researchers found that daily self-weighing can help prevent holiday weight gain by allowing individuals to make behavioral changes based on their weight changes. Participants who engaged in daily self-weighing maintained or lost weight during the holiday season, while those who did not gained weight.
Research presented at ATS 2019 suggests that violence exposure and depression may contribute to the development of asthma in high school students. Additionally, promoting healthy lifestyle habits such as a balanced diet and regular exercise may help reduce the risk of asthma in adolescents.
A new study found that employees who purchased unhealthy food at work had an unhealthy diet outside of work and higher risk factors for diabetes and cardiovascular disease. The study suggests that workplace wellness programs can encourage healthier eating habits and reduce chronic conditions.
Research in The Journal of Physiology found that exercise during pregnancy improves placental function, preventing excessive fetal growth and obesity in offspring. Maternal exercise also enhances metabolic health, reducing the risk of type 2 diabetes, heart disease, and other metabolic disorders.
A recent study by Drexel University researchers found that patients who lost significant weight before a kidney transplant had an 18% higher risk of death after the procedure. The study analyzed data from over 94,000 transplant recipients and found that even planned weight loss could be dangerous if not closely monitored.
Research suggests that exposure to phthalates, commonly found in everyday items, may increase the risk of metabolic disorders such as obesity and diabetes. Higher levels of phthalate exposure were associated with markers of impaired liver function, insulin resistance, and cholesterol in people with obesity and diabetes.
Researchers discovered that removing a pair of negative immune signals can stimulate beta cell proliferation, allowing the pancreas to produce more insulin. The findings, made in mice, could lead to new treatments for Type 1 and Type 2 diabetes and obesity.
A Penn Medicine study found that compound SR9009 can affect cell growth and metabolic function without the presence of protein REV-ERB, challenging previous understanding of its effects on obesity and diabetes. The research has significant implications for researchers and the general public.
Research finds Australia's life expectancy at birth has slowed, requiring better control of health risk factors like obesity to achieve future increases. The rate of growth in Australia is now falling behind most other high-income nations.
A new study found that weight loss medications are extremely lowly used among eligible veterans, with only about one percent receiving treatment. Barriers such as insurance coverage, age, and ethnicity drive underuse of these medications, highlighting the need for additional research to better understand obstacles.
The Obesity Medicine Association announces major updates to its adult obesity algorithm, addressing key health consequences and treatment strategies. The new guidelines provide comprehensive guidance for healthcare professionals on managing the chronic disease of obesity, including nutrition, physical activity, and pharmacotherapy.
A study analyzing Philadelphia's implementation of a 1.5-cent-per-ounce tax on sweetened beverages found it led to increased prices and significant declines in sales. The tax also prompted increases in purchases from neighboring areas.
A recent study by CRCHUM researchers has identified a key brain protein, acyl-CoA-binding protein (ACBP), in controlling food intake and energy expenditure. The study found that this protein enables astrocytes to communicate with neurons, regulating weight maintenance.
A prospective study of 18,481 pregnant women found obesity in early pregnancy associated with spontaneous abortion, preterm birth, and large birth weight. Being underweight during pregnancy was linked to early neonatal deaths and low birth weight.
Researchers successfully changed some of the composition of the gut microbiota of patients with obesity using fecal matter from a lean donor. The study found alterations in stool samples and decreased levels of a specific bile acid, suggesting potential new weight-loss therapy.
A new minimally invasive procedure, endoscopic sleeve gastroplasty (ESG), has shown significant weight loss in a five-year study of over 200 obese patients. The procedure resulted in an average weight loss of up to 15-20% of total body weight, with less than 1% complications.
Researchers at Duke-NUS Medical School found that older adults with obesity can expect 6 more years of remaining life with physical limitations and 5 less years without them at age 60. They also observed similar patterns at ages 70 and 80, regardless of gender, ethnicity, or education status.
A recent study has found that rural areas are experiencing a faster rate of obesity growth than cities, with an average increase of 2.1 kg/m2 in women and men since 1985. This trend is driven by factors such as increased income, better infrastructure, and changes in food consumption patterns.
A new study from Illinois Institute of Technology found that meals including fresh avocado significantly suppressed hunger and increased meal satisfaction in overweight and obese adults. The research also showed that avocados limit insulin and blood glucose excursions, reducing the risk of diabetes and cardiovascular disease.
A study published in the journal Obesity found that people on lower incomes are more likely to have obesity due to psychological distress and emotional eating. The researchers discovered a mediating role of psychological distress and emotional eating in explaining the relationship between socioeconomic status and BMI.
Researchers found that a high-sugar diet in fruit flies changes the way they taste sweets, leading to overeating and obesity. The study suggests that reducing sugar intake may help regulate food intake and curb obesity-related chronic diseases.
Researchers at the University of Chicago discover that obesity reprograms immune cells in breasts to promote tumor formation in triple-negative breast cancers. Obesity promotes inflammation through metabolically-activated macrophages, which fuel tumorigenesis and encourage tumor growth.
A study found that maternal obesity affects sperm RNA, influencing offspring's behavior and health. Sperm tsRNAs contribute to transgenerational transmission of addiction and obesity traits in mice.
Researchers found that a specific molecule called interleukine-6 (IL-6) plays a crucial role in regulating energy balance. In obese rodents, IL-6 levels decrease, leading to increased body weight and fat accumulation. The study suggests that targeting this molecule could lead to effective anti-obesity treatments.
A new study from Binghamton University found that comic book characters have exaggerated physical features, with males averaging obesity and females near underweight. The researchers argue that these traits are a reflection of supernormal stimuli, beyond human capabilities.
The proportion of pregnant women with obesity has doubled from 22% in 2010 to 44% in 2018, according to a new hospital study. The findings also show a rising incidence of caesarean section births alongside increasing BMI.
A new study published at the European Congress on Obesity highlights the significant impact of obesity and excess weight on premature mortality from non-communicable diseases. According to the research, controlling or 'wiping out' obesity and overweight could reduce premature deaths by up to 31% in some countries.
An international study found that countries with high rice consumption have lower obesity levels, even after adjusting for other risk factors. The researchers estimate that increasing average rice intake could reduce the worldwide prevalence of obesity by 1%.
A high intake of phenolic acids associated with a healthy diet is linked to a decreased risk of postmenopausal breast cancer. The study found that women who consumed the most hydroxycinnamic acids, particularly chlorogenic acids found in coffee and fruits, had a 62% lower risk of developing breast cancer compared to those with low intake.
The ESMO Breast Cancer Congress stresses the need for a multidisciplinary approach to patient care, including cardiovascular assessment and nutritional support. A study presented at the congress found that dietary guidelines can lead to weight loss and improved quality of life in breast cancer patients.
A quarter of patients in Scotland have never had their body mass index (BMI) recorded by their GP, according to new research. The study found that only 20-42% of general practices were recording up-to-date BMI data, with significant variations across practices.
An international study of 14,500 people with obesity and 2,800 healthcare professionals found a significant disconnect between their perceptions. Only 7% of people with obesity reported not being interested in losing weight, despite 71% of healthcare providers believing this.
A new study of 2.8 million UK adults found that higher BMI is associated with a significant increase in the risk of type 2 diabetes, sleep apnoea, heart failure, high blood pressure, and premature death. Adults with severe obesity class III are 12 times as likely to develop type 2 diabetes.
Research by European Association for the Study of Obesity reveals that obese individuals who commute by car have a 32% higher risk of death from any cause. Active commuting, mainly cycling and walking, reduces this risk, but heart disease risk remains increased.
A new study led by Harvard T.H. Chan School of Public Health found that consuming propionate may trigger a cascade of metabolic events leading to insulin resistance and hyperinsulinemia. The research also showed that mice exposed to chronic propionate resulted in weight gain and insulin resistance.
Researchers at Nanyang Technological University have developed a self-inflating weight management capsule called EndoPil. The capsule induces a sense of fullness, helping obese patients manage their weight without the need for invasive procedures.