Articles tagged with Obesity
A recent study found that nearly 73% of patients with obesity experienced increased anxiety, while 84% reported depression. The pandemic disrupted their access to healthy food and exercise opportunities, leading to increased stress eating and decreased physical activity.
A systematic review and meta-analysis found that individuals with sarcopenic obesity had a similar prevalence of metabolic syndrome as those without sarcopenia. The study also did not detect an association between the presence of sarcopenic obesity and an increased risk of metabolic syndrome.
Women with non-alcoholic fatty liver disease (NAFLD) in pregnancy face increased risks of maternal and infant health complications. The study found that NAFLD is associated with hypertensive complications, preterm birth, and maternal bleeding after delivery, independent of other metabolic diseases.
A recent study published in Neurogastroenterology & Motility found that high-fat diets change the nutrient-sensing capacity of Enterochromaffin (EC) cells in mice, leading to increased serotonin levels and potential implications for obesity and type 2 diabetes
Scientists identify key proteins required for autophagy gene transcription during fasting, enabling activation of autophagic pathways to maintain a normal body weight. The discovery provides new insights into the molecular mechanisms underlying autophagy and its potential therapeutic applications.
The $11 million grant will support four research projects investigating lipid metabolism, reproductive fat tissue's contribution to preeclampsia, and the neural circuit linking metabolism and anxiety. The goal is to develop new treatments for obesity-related illnesses.
Researchers found that anti-obesity medications like phentermine and topiramate can significantly reduce weight regain in patients after Roux-en-Y gastric bypass surgery. The study, which analyzed nearly 1,200 patients, showed a 10% decrease in cumulative weight regain.
A Penn State study found that eating a meal with six grams of spice blend reduced inflammation markers compared to meals with less or no spices. The researchers discovered anti-inflammatory properties in the blend, which may help offset inflammation caused by high-carb and high-fat meals.
A UBC scientist has identified a gene called ALK that plays a role in resisting weight gain in humans. The study found that a mutation in the ALK gene is associated with thinner individuals, and that deleting the gene in mice made them resistant to diet-induced obesity.
A new Swedish study found no correlation between obesity and the distance to fast food restaurants or gyms, contradicting previous research. The study also showed a significant association between neighborhood deprivation and obesity.
The study found that women who watched videos of themselves and their peers experienced increased autonomous motivation and self-efficacy, leading to a significant decrease in fat intake. The intervention's emphasis on coping self-efficacy also reduced participants' stress levels.
A Baylor University study found that exposure to obesogens, chemical compounds disrupting normal metabolic processes, can lead to increased susceptibility to weight gain across the lifespan. The study highlights the potential effects of chemicals in consumer products on lipid-related diseases, including obesity and fatty liver disease.
A new study published in Cell Metabolism found that disulfiram, normally used to treat alcohol use disorder, can help obese mice normalize their body weight and reverse metabolic damage. The drug's anti-inflammatory properties are believed to be key to its beneficial effects.
A recent study found that excessive coffee consumption can increase the risk of osteoarthritis, arthropathy, and obesity. The research analyzed data from over 300,000 participants and used a genetic approach to establish true effects on various diseases.
Analysis of data from 147 countries found a strong association between rising incomes and increasing obesity rates, with an average increase in obesity rates for every 1% rise in GDP per capita. The study suggests that policy initiatives may be necessary to combat obesity in low- and middle-income countries undergoing income growth.
Experts recommend prioritizing surgical treatment for patients with type 2 diabetes or severe obesity due to the risk of complications from their disease and COVID-19. Bariatric and metabolic surgery can lead to significant weight loss, reduced cardiovascular risk, and improved survival.
Researchers evaluated teens with normal weight and those with obesity, type 2 diabetes or high blood pressure to assess carotid artery health. Teens with these conditions were found to have thicker and stiffer arteries, increasing the risk of early heart attacks and strokes.
Research finds that statin drugs may modulate disrupted gut microbiota and inflammation in obesity, with improved Bact2 enterotype composition in treated individuals compared to non-treated counterparts. Statin therapy may also have anti-inflammatory effects via improvement of an aberrant gut microbiota.
Research finds statin-treated individuals have lower prevalence of gut microbiota dysbiosis compared to non-treated obese individuals. The study suggests that statins may modulate harmful gut inflammation, potentially leading to a healthier microbiome.
A study published in The BMJ found that Mexico's sugary drinks tax led to significant reductions in soft drink consumption. After three years, the probability of non-consumers increased by 4.7 percentage points and low consumers by 8.3 percentage points.
Researchers at Joslin Diabetes Center have discovered two subtypes of human white subcutaneous fat cells with distinct patterns of gene expression, which may help control whether cells become mature fat cells. This study highlights the potential of bringing together biology, artificial intelligence, and data analysis to better understa...
A recent study by the University of Georgia found a slower uptake of Medicaid enrollment among low-income obese individuals compared to non-obese counterparts. The study revealed a 5.6% increase in coverage for obese individuals versus 7.4% for non-obese individuals.
A new study from the University of Gothenburg finds that weighted vests can lead to a reduction in body weight and fat mass, particularly when wearing heavy weights, while maintaining muscle mass. The researchers suggest that this is due to a built-in energy balance system that endeavors to keep body weight constant.
A study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that short-term cold exposure increased energy expenditure and improved fatty acid profiles in individuals with active brown fat. People with brown fat burned 15% more calories than those without, highlighting the organ's potential as a ta...
Researchers found that high-fat diets caused impaired cognitive function in obese rats, affecting their mental exhaustion. The study, published in The FASEB Journal, suggests a link between excess weight and compromised cognitive abilities.
Researchers unveil the structure of a key protein in human metabolism, which could lead to better obesity treatments. The study found that calcium ions play a crucial role in the protein's function, opening new paths for developing targeted pharmaceuticals.
Researchers from IKBFU, Moscow, and Kiev investigate the effects of deuterium on adipose tissue differentiation in an in vitro model. They found that varying deuterium concentrations can influence the formation of brown/beige or white adipocytes.
Researchers discovered that nociceptin neurons in the hypothalamus of mice promote consumption of high-fat food. Removing these neurons from the brain eliminated overeating in mice.
Researchers found that Orujo Olive Oil significantly reduced obesity in mice by 30%, while also decreasing body fat, hepatic inflammation and improving insulin sensitivity. The study highlights the biological value of orujo oil as a functional food with great therapeutic potential against metabolic disorders.
A new study published in PLOS Biology found that excess weight can cause poor sleep in worms, not the other way around. Researchers genetically modified worms to lose their ability to sleep and observed a severe drop in energy levels, suggesting that sleep is an attempt to conserve energy.
A new study found that the effective population size of the first Samoans was small, ranging from 700 to 3,400 people, with population growth starting around 1,000 years ago. The research highlights the importance of population history and size in understanding health conditions such as obesity and diabetes.
Research published in Diabetologia found that obesity increases type 2 diabetes risk by at least 6 times, even among those with low genetic risk. The study highlights the importance of weight management and healthy lifestyle in preventing type 2 diabetes across all genetic risk groups.
Researchers discovered a synthetic gold-based compound that inhibits adipogenesis and reduces key metabolites, potentially treating obesity. The D-AuNPs showed nontoxicity to cells at high concentrations, offering a new avenue for obesity medicine.
A study published by The Endocrine Society highlights shared disease pathways between COVID-19 and type 2 diabetes, requiring new approaches in treatment for hospitalized patients. Commonly used diabetes medications may pose risks in severe coronavirus infections.
A large observational study of over 33,000 women found that those born by cesarean section were at higher risk of developing obesity and type 2 diabetes in adulthood. The study, published in JAMA Network Open, controlled for various factors and found a significant association between cesarean births and increased risk of these conditions.
A study of 519,513 UK adults found a significant correlation between depression and obesity. Antidepressant prescriptions also increased with rising weight, highlighting the need for tailored guidance.
A larger thigh circumference may be associated with lower blood pressure and a reduced risk of heart disease in people with obesity. Thigh circumference could potentially be used as an indicator for earlier detection and prevention of high blood pressure and related complications.
Two studies from Boston University School of Public Health found that patients with higher BMIs were up to 158% more likely to use prescription opioids long-term. Osteoarthritis, other joint disorders, and back pain accounted for most opioid prescriptions linked to obesity.
A new study published by Oxford University Press USA found that mat Pilates training significantly reduces arterial stiffness and blood pressure in young obese women with elevated blood pressure. The study, which included 12 weeks of mat Pilates training, also found a decrease in body fatness.
A new study published in the Journal of the Endocrine Society found that people with very poor fitness at the beginning of a behavioral weight loss program lose less weight in the long term. Adults with poor or better fitness lost nearly twice as much weight over 18 months compared to those with very poor fitness.
A survey of resident physicians found that most felt uncomfortable managing obesity despite its increasing prevalence. The study highlights the need for improved education in obesity management to improve patient care.
Researchers found that bariatric surgery significantly decreased liver enzymes, Fatty Liver Index, and BARD score in patients with NAFLD. Gastric bypass was associated with the greatest reduction in liver damage.
An animal study found that coconut oil consumption reduces cholesterol and blood glucose levels, and fatty liver disease in obese female mini-pigs. The study suggests that coconut oil may be used to treat metabolic syndrome, particularly in women with obesity.
Patients with superobesity are more prone to regain weight after bariatric surgery due to unconscious food cravings and attentional bias. Research found that pre-conscious and conscious attentional biases play a significant role in weight regain, suggesting that cognitive processes similar to addiction may be present in morbid obesity.
Researchers have discovered a molecular accelerator of leptin action in the brain called Sh2b1, which promotes the stimulation of the sympathetic nervous system and activates brown fat. This activation increases energy expenditure and protects against obesity and metabolic disease.
A new study links pregnant women's PFAS exposure to their granddaughters' increased obesity risk. The research found that higher levels of PFAS in grandmothers were associated with a greater risk of obesity in granddaughters, even when controlling for other factors.
Studies confirm that breast reduction surgery significantly improves physical health, including pain levels and physical function, as well as mental wellbeing. Women of all shapes and sizes benefit from the surgery, including overweight or obese individuals who were previously barred from the procedure.
Researchers from Kumamoto University found that Melinjo seed extract activates the beneficial hormone adiponectin, improving obesity and diabetes. The study discovered individual genotype differences affect efficacy.
A new study reveals that sugar-rich diets can lead to early death, but not due to obesity. The researchers found that the build-up of uric acid is a key factor in this process. By providing flies with access to water, they were able to prevent the accumulation of uric acid and subsequent shortened survival.
A nationwide study found that bariatric surgery significantly reduces the risk of heart attacks and strokes among obese patients. The surgery was associated with a 60% lower rate of fatal and non-fatal heart attacks and stroke, as well as significant weight loss and improved type 2 diabetes management.
Researchers at Max Delbrück Center have identified protein EHD2 as a key regulator of fatty acid uptake in fat cells. The study found that people with normal weight produce more EHD2 than those who are overweight, suggesting a correlation between EHD2 levels and fat metabolism.
A large Kaiser Permanente study found that patients who underwent bariatric surgery maintained significantly more weight loss at 5 years compared to those who did not have surgery. Gastric bypass surgery showed better results than sleeve gastrectomy, with fewer participants regaining weight.
A ketogenic diet reduced liver fat content and improved insulin resistance in overweight participants. The diet also increased hydrolysis of triglycerides and promoted ketogenesis, suggesting a possible mechanism for reversing nonalcoholic fatty liver disease.
Researchers found that gastric bypass surgery alters both fecal and mucosal microbiomes, leading to improved metabolic outcomes. The study suggests manipulating the gut microbiome could be a potential alternative to surgery for sustained weight loss.
Researchers found that weight-loss surgery increased colorectal cancer risk by 20% and mortality rates among obese patients, highlighting the need for post-operative surveillance.
A new study published in Environment International links poor air quality to changes in the human gut microbiome, increasing the risk of obesity and diabetes. Young adults exposed to higher levels of ozone showed less microbial diversity and more species associated with obesity and disease.
Researchers developed a computer program analyzing molecules in blood plasma to identify individuals at risk of becoming overweight and developing obesity-related diseases. The test is 90% accurate in detecting whether the subject will gain weight without intervention, also predicting diabetes and other health risks.
Obesity increases levels of peroxynitrite-making enzymes in tiny cell membranes, silencing TRPV4 and lowering calcium entry. This leads to increased blood pressure. Targeting peroxynitrite or enzymes that make it may be an effective way to treat high blood pressure in obesity.
A study by Université Laval researchers suggests that bacteria may play a role in the development of type 2 diabetes in individuals with severe obesity. The researchers found distinct bacterial signatures in diabetics' blood, liver, and fat deposits compared to non-diabetics.
A Mayo Clinic-led study reveals that rapid fat degradation occurs in acute pancreatitis, triggered by PNLIP enzyme, and worsens disease outcomes. Obesity exacerbates pancreatitis risk, while unsaturated fats increase organ failure risk.