Articles tagged with Obesity
Researchers at the University of Illinois Chicago report that robotic kidney transplants produce similar one- and three-year patient survival rates as those seen among nonobese patients. The study included over 230 robotic-assisted kidney transplants in patients with obesity, achieving dramatic reductions in post-surgery wound infections.
A research team found that consuming cholera toxin B stimulates health-protective immune responses that counteract age-associated obesity. The study used animal models and found that the toxin helped restore immune homeostasis and reduce inflammation, leading to leaner physiques and improved health outcomes.
Researchers from Massachusetts General Hospital found that uninfected adolescents and young adults born to mothers with HIV have a fourfold increased risk of obesity and asthma-like symptoms. The study revealed metabolic and immune consequences of in utero HIV exposure.
A study published in JAMA Network Open found that 86% of diet trials amended their primary outcomes. This discrepancy raises questions about the rigor of these trials and potential biases. Researchers are calling for more investment in rigorous diet research to pin down the effects of dietary changes.
Researchers found that bariatric weight-loss surgery can release toxic chemicals like PCBs and organochlorine pesticides stored in fat into the bloodstream. Patients born before 1976 showed higher levels of these compounds due to greater exposure to environmental toxins.
A recent study led by Tulane researchers reveals that while more adults are attempting weight loss, the average BMI of Americans continues to increase. Researchers found that only a minority of those who tried to lose weight achieved success, highlighting the need for effective weight loss strategies.
Preliminary research suggests that weight-reduction surgery can help reduce the risk of stroke and death in obese patients. The study found that participants who underwent bariatric surgery were 69% less likely to experience a clot-caused stroke and 68% less likely to die during follow-up compared to those who did not receive surgery.
Pregnant women with low vitamin B12 levels experience increased fat production and reduced breakdown, predisposing them to obesity. A recent study found that vitamin B12 deficiency impairs fat cell metabolism, leading to increased inflammation and impaired metabolic function.
A new study reveals that bariatric surgery can lead to successful weight loss and better diabetes control in older adults. After two years, the patients had lost an average of 24% of their body weight and seen a significant reduction in HbA1c levels. The study suggests that age alone should not be considered a contraindication to baria...
A new study found that bariatric surgery significantly reduces the risk of cancer in patients who lose at least 20% of their body weight. The risk was reduced by 50% compared to those who did not experience significant weight loss after surgery.
Women with a genetic predisposition for breast cancer were 2.5 times more likely to develop malignancy without weight-loss surgery, but the risk was significantly reduced after bariatric or weight-loss surgery. The study found that weight-loss surgery cut the overall risk of developing cancers linked to obesity by 20 percent.
A large-scale study found that high waist circumference is associated with an elevated risk of obesity-related dementia in older populations. Participants with a waist circumference of 90cm or more had a significantly increased risk of dementia after adjusting for other factors.
Researchers developed a definition of hyper-palatable foods using nutrition software and applied it to 7,757 food items. Most US foods (62%) met the criteria for enhanced palatability, with high fat and sodium being the most common factor. The study aims to inform policymakers on how to address hyper-palatable foods in children's diets.
A new study found that intensive lifestyle interventions, combined with medication, produce clinically significant improvements in quality of life outcomes for obese patients. Participants who received both liraglutide and behavioral therapy achieved more meaningful weight-related quality of life improvements compared to those who rece...
A new calculator developed by Cleveland Clinic researchers can estimate a patient's risk of developing major health complications over the next 10 years depending on their treatment choice. The calculator provides personalized evidence-based information on heart disease, stroke, and other risks with usual care versus surgical treatment.
Patients who underwent metabolic surgery had a lower risk of developing systolic heart failure and dying from recurrent myocardial infarction compared to those without surgery. The study found significant cardiovascular benefits of metabolic surgery, emphasizing its potential as part of the treatment plan for patients with severe obesi...
A new study presents evidence that patients with a BMI of 30 or higher may achieve greater health benefits from weight loss surgery than previously thought. Researchers found that these patients are more likely to reach a healthy weight, have improved quality of life and resolve type 2 diabetes.
A new web-based calculator predicts a patient's likelihood of dying from complications or experiencing serious health issues due to type 2 diabetes and obesity, whether they undergo metabolic surgery or continue with standard medical therapy. The Individualized Diabetes Complication Risk Calculator provides a personalized risk score ba...
A Veterans Affairs study found that bariatric surgery did not result in lower healthcare costs for nearly 10,000 veterans over a 10-year period. Despite the benefits of weight loss and improved health, patients required additional treatment for short-term complications, such as nausea and dehydration, which increased costs.
Researchers have discovered that avocatin B, found only in avocados, counters incomplete oxidation in skeletal muscle and the pancreas, reducing insulin resistance. The study found significant weight loss and improved insulin sensitivity in mice fed with a high-fat diet supplemented with AvoB.
The study found that weight-loss surgery significantly reduced healthcare expenditures for veterans with severe obesity over a period of up to 10 years. The observed decrease in medical costs was attributed to improved health outcomes and reduced need for ongoing medical interventions.
A recent study found that people with obesity share similar personality profiles with those with addictive behaviors, including uncontrolled eating. This suggests that obesity treatments may benefit from adopting methods used in addiction recovery to improve self-control.
A randomized, controlled feeding study found that eating one avocado a day was associated with lower levels of LDL (specifically small, dense LDL particles) and oxidized LDL in adults with overweight or obesity. Avocados also helped reduce oxidized LDL particles and increased antioxidant lutein levels.
China's obesity rates have nearly tripled over the past decade, reaching 14% for general obesity and 32.4% for abdominal obesity among adults. A cluster of high obesity prevalence was identified in the Beijing-Tianjin-Hebei region, highlighting the need for targeted interventions to address this growing health concern.
A study from King's College London found that sugary soft drinks are associated with both obesity and tooth wear among adults. The acidic nature of these drinks leads to tooth erosion, particularly in obese patients. This highlights the importance of monitoring calorie intake through acidic sugar-sweetened drinks.
A study published in PLOS Genetics found that obesity is associated with a higher risk of type 2 diabetes in women and chronic obstructive pulmonary disease and chronic kidney disease in men. The researchers analyzed data from over 423,000 participants and identified distinct patterns of disease association for each sex.
Researchers link high glucose levels to impaired circadian clock function in obesity, which may drive cardiovascular disease. Intermittent fasting and clock repair drugs show promise in restoring normal circadian rhythms and improving cardiovascular health.
A study found that plant-based diets and Mediterranean diets are associated with high levels of friendly gut bacteria, aiding nutrient production and SCFA energy for cells lining the colon. Plant protein helps biosynthesis of vitamins and amino acids.
A recent study published in the European Respiratory Journal has provided evidence that fatty tissue builds up in the airway walls of individuals who are overweight or obese. This accumulation alters the normal structure of the airways and leads to inflammation in the lungs, which may contribute to increased asthma symptoms.
A recent study published in The BMJ found that weight gain from young adulthood to middle age increases the risk of premature death. Maintaining a normal weight throughout adulthood is crucial for reducing this risk, especially preventing weight gain during early adulthood.
Researchers have discovered a causal link between high blood pressure, obesity, and reduced lifespan in a massive genetic analysis of 700,000 individuals. By analyzing polygenic risk scores, the team identified blood pressure and obesity as key drivers of human longevity.
A Norwegian study found that being overweight before age 40 significantly increases the risk of several types of cancer, including endometrial cancer by 70%. Obesity is also linked to an increased risk of postmenopausal breast, renal-cell and colon cancers.
A new medical device called Sleeveballoon has been tested in rodents and produced impressive results on body weight, fatty liver, and diabetes control. The device reduces food intake by 60% and blood glucose levels by 65%, mimicking the effects of traditional bariatric surgery with a minimally invasive approach.
A University of Waterloo study found that Grindr's anonymous nature and lack of size inclusivity contribute to weight stigma among gay men, leading to body dissatisfaction and sexual objectification. Protective factors like positive self-esteem and social support can mitigate these effects.
New research reveals that maternal obesity accelerates the aging process in offspring, leading to increased susceptibility to diabetes and heart disease. Exercise by the offspring can help mitigate these risks, highlighting the importance of early life conditions on future health outcomes.
Researchers found that overweight individuals had the lowest mortality risk among those with established heart failure, contrary to previous expectations. The 'obesity paradox' suggests that obese patients may tolerate disease-modifying and prognostic medications better than non-obese patients.
Researchers found that women with asthma are more likely to have lower levels of free testosterone and estradiol compared to those without asthma. Elevated sex hormone levels were associated with reduced odds of asthma in both men and women, particularly obese individuals.
A study of 3,778 African American participants found an association between shorter sleep duration and lower body mass index (BMI), with more than 30% of participants overweight or obese. The researchers recommend promoting better sleep hygiene to help combat obesity.
A new paper published in JAMA recommends a continuum of care approach, including lifestyle modification therapy, medications, and bariatric surgery, to treat adolescents with obesity. The study suggests that filling the treatment gap between lifestyle modification and surgery is crucial.
Researchers found a key driver of nutrient absorption synchronization with Earth's day-night light cycle, linking it to weight gain. The commensal bacteria program the metabolic rhythms by activating protein histone deacetylase 3 (HDAC3), which enhances fat absorption.
Researchers have discovered that a lipid produced by brown adipose tissue, called 12-HEPE, helps reduce blood sugar levels in obese mice. The study found that 12-HEPE promotes glucose uptake into both skeletal muscle and brown adipose tissue, leading to improved glucose tolerance.
A new mouse study shows that disrupting the daily routine of gut microbes in mice increases the risk for metabolic dysfunction and obesity. The findings suggest a link between microbiota damage and human obesity, particularly in modern environments with antibiotics or long-distance jet travel.
Scientists have identified a signaling channel in the carotid body that links obesity to high blood pressure, paving the way for potential new treatments. Blocking this molecule can effectively lower blood pressure in obese mice.
Researchers at the University of Würzburg are developing a new therapy approach using virtual reality avatars to combat obesity. The avatars aim to provide a realistic body image, promoting acceptance and self-reflection in patients struggling with the condition.
A new tool kit provides real-world guidelines for counseling weight loss in primary care settings, offering a 21-session treatment manual modeled on the schedule of visits recommended by CMS. This approach has shown favorable weight losses of 5.4% at 6 months and 6.1% at 1 year.
A large-scale implementation of an enhanced recovery program (ERP) reduced rates of extended hospitalization for bariatric surgery patients by nearly half. The protocol, known as ENERGY, improved patient outcomes through measures such as minimizing fluid overload and implementing opioid-sparing pain management strategies.
Increasing nut consumption by half a serving a day may help stave off gradual weight gain, according to researchers. Substituting unhealthy foods with nuts was associated with lower risk of obesity and weight gain.
The Obesity Society has released a new evidence-based treatment protocol for intensive behavioral therapy (IBT) to treat obesity in primary care settings. The MODEL-IBT program provides 14 visits in the first 24 weeks, with 7 additional monthly visits through week 52.
A new study found that fat mass index is associated with a higher risk of cardiovascular events in people with type 2 diabetes. Researchers analyzed data from the ACCORD study and found that participants with higher fat mass were at increased risk, while lean body mass did not provide protection.
A new study from the University of Copenhagen found that overweight dog owners are more likely to have obese dogs, with a correlation between treats used for training and comfort. The study also reveals that castration triples the risk of being heavy or obese in male dogs.
Researchers discovered that inhibiting tanycytic TSPO increases energy expenditure and decreases appetite in high-fat diet-induced obese mice. This finding suggests a potential therapeutic strategy for treating metabolic diseases like obesity.
A new study published in Alimentary Pharmacology & Therapeutics found a strong association between obesity and chronic diarrhea, independent of dietary, lifestyle, or medical factors. Obesity was 60% more likely to cause chronic diarrhea compared to normal weight individuals.
A study published in Heliyon found that early life experiences shape individuals' beliefs about themselves and the world, contributing to chronic obesity and frequent bingeing. Schema therapy model can help address these underlying issues by identifying and changing maladaptive schemas and coping modes.
A UK study found that the proportion of younger adults diagnosed with type 2 diabetes has increased since the start of the century. Younger cases have a more aggressive metabolic profile, including higher BMI, blood glucose levels, and cholesterol levels. This trend is associated with a higher risk of cardiovascular disease and mortality.
Forager-farmers in Bolivian lowlands experience changes in body mass and diet over nine years, with increased use of cooking oil contributing to weight gain. Despite remarkable cardiovascular health, the Tsimane' population faces health challenges associated with high-calorie foods.
A new study found that obesity increases the risk of type 2 diabetes by 5.8-fold, while genetic predisposition and unfavorable lifestyle factors contribute less to the risk, but still play a role in its development. Lifestyle interventions can help delay the onset of T2D among high-risk subjects.
High levels of progesterone enable increased mineralocorticoid receptor expression, leading to blood vessel damage in young females with obesity. The study found that removing or blocking progesterone and aldosterone receptors can prevent blood vessel dysfunction.
Researchers at SDSU examine the role of sensory experience in shaping healthy food choices, finding that associating healthy foods with pleasure can increase interest in purchasing or eating them. Time and money are identified as primary barriers to accessing healthy foods.
A new study found that Japanese-American adults with a normal body mass index have a significantly higher risk of developing diabetes compared to their non-Hispanic white counterparts. The study revealed that younger respondents, never smokers, and those with higher education levels were less likely to have diabetes.
Researchers from Trinity College Dublin isolated a family of proteins linked to better control of blood sugar levels in type 2 diabetes patients. These IL-36 cytokines alter the intestinal microbiome, potentially mitigating insulin resistance and glucose build-up.