Articles tagged with Obesity
A study of 26,000 heart transplants found that patients receiving hearts from severely obese donors had similar short-term and long-term outcomes as those receiving hearts from non-obese donors. The research has the potential to expand the critically low donor pool by increasing the number of obese donors.
A new study published in PLOS Medicine found that metabolic surgery reduces the risk of major adverse cardiovascular events and death for individuals with hypertension and a BMI over 35kg/m2. The surgery was shown to be effective in treating hypertension, suggesting it as an option for patients with obesity and high blood pressure.
The article reviews mechanisms linking obesity and diabetes to COVID-19 severity, suggesting that bacterial conditions work with the virus to increase disease severity. A combined deficiency in ACE2 caused by COVID-19 leads to impaired gut barrier function, allowing bacteria and toxins to leak into the circulation.
Researchers found that the typically 'bad' APOE ε4 variant can also protect against obesity and type 2 diabetes, while the 'good' ε2 variant increases risk of certain conditions. The study's findings provide valuable insights into how the APOE gene impacts health and disease.
A mother's high-fat diet during pregnancy may alter the taste buds of her offspring, leading to a greater attraction to unhealthy food and obesity in adulthood. The study found that adult progeny fed with such a diet had more sweet-taste receptors inside their taste buds.
A study of 270 overweight women found no link between gut microbiota composition and the incidence of gestational diabetes. However, the combination of fish oil and probiotics was shown to modulate gut microbiota in women who did not develop gestational diabetes. Further research is needed to confirm these findings.
Researchers found that households in states with Medicaid expansion increased purchase of diet soda and bottled water but showed no change in regular soda consumption. The study suggests a spillover effect of the program promoting healthier dietary choices.
Patients with the highest obesity risk who received a tailored coaching program lost 5% of their body weight, compared to 0.5% in usual care group. The study demonstrates the importance of convenient and accessible interventions in overcoming barriers to weight loss.
In a 11-year study, testosterone therapy significantly reduced weight and improved various metabolic markers in obese men with low testosterone. The treatment also led to lower rates of mortality and cardiovascular events compared to controls.
A new study found that people with obesity who gain weight tend to perceive their body size as smaller than it actually is. Despite improvements in accuracy over time for those maintaining a stable weight, the degree of body image distortion remained significant in weight gainers.
A study of UK data from the ACTION-IO study found that individuals with obesity waited an average of 9 years before discussing weight loss with their healthcare provider, significantly longer than the global average. This delay increases the risk of developing related health conditions such as type 2 diabetes and cancer.
The European Society of Endocrinology reviews evidence on hormone involvement in COVID-19 infection, disease severity, and treatment. Obesity, cardiovascular disease, and sex hormones are identified as risk factors.
A study of over 550,000 adults in the UK found that losing an average of 13% of body weight reduced the risk of developing type 2 diabetes by 42%-44%, sleep apnoea by 22%-27%, high blood pressure by 18%-25%, and dyslipidaemia by 20-22%. The study suggests that intentional weight loss can markedly reduce disease risk in people with obes...
A new study finds that obesity can lead to an overactive immune response to COVID-19, impairing the body's ability to fight the virus. The review highlights the importance of understanding how obesity interacts with new COVID-19 treatments and vaccines.
A nationwide study found that consuming even half a standard drink per day increases the risk of obesity and metabolic syndrome. The risk rises with alcohol intake, with men and women experiencing higher odds of obesity and metabolic syndrome when drinking more than half a standard drink per day.
Research suggests that the immunological disturbances found in COVID-19 and obesity overlap, contributing to increased disease severity and mortality. Fat cells accumulate fat and become larger during weight gain, resulting in chronic low-grade inflammation in obesity.
A nationwide Danish study found that individuals with hospital-diagnosed overweight or obesity have a 60% higher risk of dying compared to the general population. The risk of dying was highest within the first year of diagnosis and remained markedly higher over the whole study period.
A small study using mobile eye-tracking technology found that normal-weight consumers noticed and looked at their chosen food earlier and longer than those with overweight or obesity. The researchers also discovered a tendency for all consumers to focus on lower-energy-density foods like fruits and vegetables more often.
A survey of over 6,000 US and UK adults found that attitudes towards obesity are changing, with more Americans viewing it as a medical problem. In contrast, nearly one-third of UK respondents still blame people with obesity for their condition.
A UK survey of over 800 adults found that most struggled with weight management during the pandemic, citing increased snacking and reduced exercise. However, those who received weight-management support continued to lose weight and reported higher wellbeing.
A study of 1177 UK adults found that eating more in the evening is associated with a higher total energy intake and lower diet quality. The research suggests that consuming a lower proportion of calories at night may lead to a lower daily energy intake.
A new study found that obesity-related illnesses frequently occur in people with a BMI over 30, yet only 9% had obesity recorded as a cause of death. Researchers argue that obesity is not being accurately documented on medical certificates, highlighting the need for further studies.
Research shows that people with obesity are at higher risk of severe COVID-19 disease and mechanical ventilation. The study analyzed ICU patients and found a clear correlation between BMI and disease severity, with those with severe obesity facing the highest risk.
Research suggests that not all vegetarian diets are created equal, with healthier choices linked to maintaining normal blood pressure, blood lipids, and blood sugar. Whole grains, fruits, vegetables, nuts, and olive oil were found to be key contributors to better heart health.
New studies demonstrate significant reductions in ALT, hepatic fat, and liver damage biomarkers for patients with non-alcoholic steatohepatitis (NASH). The treatments target lipid metabolism and show potential to address type 2 diabetes and obesity.
A new study published in Obesity found that an intensive lifestyle intervention (ILI) focused on weight loss lowered the incidence of obesity-related cancers in adults with overweight or obesity and type 2 diabetes. The ILI reduced cancer incidence by 16% compared to a Diabetes Support and Education comparison group.
A new study published in Nutrition and Metabolism found that an eight-week very low-carbohydrate diet improved body composition, fat distribution, and metabolic health in older adults with obesity. The diet also preserved skeletal muscle mass without intentional caloric restriction.
Fatty acid binding proteins (FABPs) are chaperones that coordinate fatty acid transport between cells. Research by University of Louisville immunologist Bing Li reveals their role in lipid metabolism, obesity, and disease development.
Researchers at the University of Bath found that generic public health messages are more effective than tailored advice in shifting dietary habits. Participants who received generic information selected food baskets with less total fat and spent 34% less on unhealthy items compared to those who received no information.
Researchers found a statistically significant relationship between morbid obesity and COVID-19 cases and deaths in the US. Morbid obesity rates are positively correlated with COVID-19 death rates, explaining 9% of the variation.
New research from WashU Medicine finds that weight loss after surgery, not the surgery itself, drives improvements in metabolism and remission of diabetes. The study compared patients who lost weight through gastric bypass surgery with those who achieved equivalent weight loss through diet alone.
A study by the University of Oxford found a connection between traffic noise and obesity, with long-term exposure associated with a 2% increase in obesity prevalence. Lifestyle factors were accounted for, but air pollution was also considered.
A new study by Boston University School of Public Health found that weight changes between early adulthood and midlife are crucial in determining a person's risk of early death. Participants whose BMI decreased from obese to overweight range had half the risk of dying compared to those who remained obese throughout their lives.
Obesity, as measured by body mass index and abdominal fat content, is associated with an increased risk of heart disease and progression of kidney disease in patients with chronic kidney disease. Lower physical fitness levels are also linked to a higher cardiovascular risk.
A trio of Danish researchers warn that lockdowns could lead to an explosion in obesity rates due to increased consumption of high-energy foods and decreased physical activity. The study highlights the need for counter strategies to promote healthy eating habits and physical activity while combatting COVID-19.
Pregnant obese women are at higher risk of early and late-onset hypertensive disorders, with the risk increasing with higher body mass indexes (BMI). The study found a strong association between maternal obesity and both early- and late-onset hypertensive disorders of pregnancy.
A retrospective cohort study found obesity was a significant independent risk factor for death from COVID-19. Patients with high BMI were 4 times more likely to die within 21 days of diagnosis compared to those in the normal weight group.
A University of Houston researcher has identified sphingomyelinase as a key player in the development of obesity-induced cardiovascular disease. The study aims to develop therapeutic strategies for treatment or prevention of this condition, which affects millions worldwide.
A recent study by Norwegian University of Science and Technology researchers Roger Andre Søraa and Eduard Fosch-Villaronga calls for exoskeleton designers to consider inclusivity in their designs. The goal is to make the technology accessible to a broader range of users, including those with different heights, weights, and genders.
A new study found that 20% of middle-aged UK South Asians have a very severe vitamin D deficiency, which can lead to health problems such as osteomalacia. The study also identified factors like geographic location and BMI as contributors to the deficiency, highlighting the need for targeted public health campaigns.
A recent study by Boston University School of Public Health found that losing weight between young adulthood and midlife can lower the risk of developing arthritis. The researchers estimated that nearly a quarter of arthritis cases in the US are attributable to excess weight, corresponding to approximately 2.7 million people.
The new clinical practice guideline published in CMAJ recommends a holistic approach to obesity management, focusing on root causes and patient-centered outcomes. The guideline targets primary health care professionals, policy-makers, and people living with obesity.
A study found that African Americans with higher body mass index (BMI) were more likely to develop severe coronavirus disease 2019 (COVID-19) and require intensive care unit (ICU) admission. Obesity was identified as a significant determinant of disease severity in this population.
Non-alcoholic fatty liver disease (NAFLD) affects both obese and non-obese individuals, with distinct differences found in male and female patients of varying body mass indexes. Key findings include lower skeletal muscle mass and insulin resistance in non-obese NAFLD patients compared to their obese counterparts.
A Wayne State University team has made significant breakthroughs in understanding the causal relationships between nonalcoholic fatty liver disease (NAFLD), type-2 diabetes, and obesity. They discovered two subtypes of NAFLD: one caused by genetic factors and another driven by metabolic syndrome.
Research found that women with fewer social connections are more likely to be obese, while men with larger networks are less likely. The study suggests that healthcare providers should consider social activities as part of obesity treatment for non-partnered older women.
A systematic review and meta-analysis of existing studies found associations between adiposity and low semen quality parameters. Overweight and obesity were linked to reduced semen volume, sperm count, vitality, and morphology, while underweight was associated with lower normal morphology.
Researchers found that pairing bariatric surgery with LVAD heart surgery improved the eligibility of previously ineligible patients for heart transplants. After a year, 66% of patients met listing requirements and 33% received transplants.
Research suggests a hormone called leptin, which regulates appetite and metabolism, also plays a role in how the body fights off COVID-19. Elevated leptin levels can lead to a low-grade systemic inflammatory state, impairing the body's ability to fight infection, particularly in people with obesity.
A University of Queensland study has found that early menstruation increases the risk of hot flushes and night sweats at menopause by 50%. Women who started menstruating before age 14 had a higher risk of experiencing both symptoms, with obesity playing a significant role.
Researchers found that fat-burning neurons in mice can grow and increase their ability to burn energy when given the hormone leptin. This discovery could lead to new treatments for obesity by targeting these neurons.
Research finds obesity and metabolic syndrome to be risk factors for severe disease from viral infections. Patients with these conditions are at increased risk of developing severe pneumonia and a cytokine storm that damages lung tissue, making them more susceptible to severe illness from influenza and COVID-19.
A new Northwestern Medicine remote weight-loss program, Opt-IN, helped participants lose 11-13 pounds, matching the success rate of the gold-standard National Diabetes Prevention Program. The program is cheaper and less burdensome than traditional treatments, making it more accessible and affordable.
Infants who are fed in the absence of hunger or beyond fullness may develop skewed perceptions of hunger and fullness, increasing their risk of obesity. Caregiver-infant interactions during feeding can shape infants' self-regulation of energy intake, with feeding responsiveness to cues being linked to obesity.
A new study from the University of Georgia finds that bariatric weight loss surgery is more expensive for public insurance patients compared to private insurance. The study analyzed a national dataset and found that Medicare patients paid the highest average cost per surgery, while publicly insured patients paid more overall.
A new study found that consuming whey protein at night increases blood sugar levels in the morning for healthy individuals. This unexpected result may help inform strategies to improve blood sugar control, but further research is needed to confirm its applicability to other populations.
A study of 212 newborns found that higher proportions of Bacteroidetes bacteria in meconium were associated with later obesity. The infant's microbiome before birth may play a role in their weight status.
A study of over 2,800 breast cancer patients found that those who were overweight or obese had poorer outcomes when treated with docetaxel. The researchers believe this is due to the fat in their bodies absorbing part of the drug before it can reach the tumor.
Scientists have identified a microRNA in obese mouse mothers that increases the odds of liver cancer in their offspring and throughout future generations. The study found that maternal obesity causes susceptibility to liver cancer in offspring, with the severity increasing over generations.
Researchers have identified Angiopoietin-2 as a hormone that enables the proper transport of fatty acids into blood vessels, preventing insulin resistance and promoting healthier weight distribution. By targeting this mechanism, scientists hope to develop novel therapeutic strategies for treating obesity-induced metabolic disorders.