Articles tagged with Obesity
Researchers found that immigrants quickly lose native microbes and acquire alien microbes more common in European-American people, resulting in a loss of gut microbiota diversity. This Westernization is associated with greater obesity and is compounded across generations.
A review of 28 studies found that bariatric surgery increased testosterone levels and improved erectile function in obese men, but had no impact on sperm parameters. However, nutritional malabsorption may counterbalance these hormonal changes.
The economic impact of obesity and excess weight in the US has reached $1.7 trillion, according to a new study by the Milken Institute. Direct health-care costs total $480.7 billion, while lost productivity adds another $1.24 trillion.
A University of California San Diego School of Medicine team will investigate a novel treatment model called Regulation of Cues (ROC) to tackle binge eating disorder and obesity in military personnel. ROC targets underlying mechanisms associated with binge eating, aiming to reduce weight and obesity.
Adults with severe obesity experienced greater initial and sustained weight loss with gastric bypass surgery compared to sleeve gastrectomy or adjustable gastric banding. The study, involving over 46,000 patients, found that gastric bypass led to a 19-pound weight loss difference at 5 years.
Researchers develop a novel combined therapy using icilin, a cold-mimicking molecule, and DMPP, a nicotinic acetylcholine receptor activator, to reduce excess adipose tissue and improve glucose metabolism. The combination is more effective than individual treatments alone.
A study of obese women who underwent gastric sleeve or bypass surgery found that weight loss reversed precancerous tissue changes in the womb. By 12 months after surgery, high-risk changes had reversed and no further pre-cancerous changes were detected.
A new study from Monash University and Peter MacCallum Cancer Centre has found a previously overlooked group of obese individuals may be at risk of developing deadly liver cancer. The research explains how obesity is linked to liver cancer, with current screening guidelines potentially missing these high-risk patients.
A new study published in American Society of Nephrology found that ideal BMI (18-25) recipients had the best organ survival rates, while there was no difference in patient survival across different BMI groups. Obesity may not be a significant barrier to kidney transplantation for obese patients.
A study found that sales employees recommend rounded watches and perfume bottles when they appear obese, and suggest more angular products when they are thin. The researchers also discovered that the level of friendliness drives the propensity to recommend round products.
A new study using genetic-based approach reveals that being overweight increases the risk of death from all causes, including cardiovascular diseases and various cancers. The study found that even within the normal weight range, a lower body mass index is associated with improved survival rates.
A study published in The BMJ found that a healthy lifestyle can significantly reduce the risk of stroke, regardless of genetic profile. Lifestyle factors such as not smoking and maintaining a healthy weight were associated with a lower risk of stroke.
Low-income obese patients lost a clinically meaningful amount of weight using a free phone app and coaching calls in a primary care clinic. The study found that 43% of participants lost more than 5% of their body weight, while 56% reached a healthy weight loss threshold.
Researchers are developing an automated virtual health coach using data from human health coaches to help participants set SMART goals and stay on track. The system will learn to automate interactions and notify human health coaches when needed, aiming to improve health behaviors among underserved populations.
A recent study published in Canine Genetics and Epidemiology found that Labrador retrievers are prone to several health issues, including obesity and ear infections. The study analyzed data on over 33,000 Labrador retrievers and revealed that chocolate-colored Labradors are more likely to develop skin and ear problems.
A new study reveals the mechanistic relationship between cytokine IL-1ß, obesity, and colorectal cancer. Increased IL-1ß levels in obese mice activate multiple pathways leading to colon cancer. The study highlights the close linkage of obesity and inflammatory response, reflecting IL-1ß's broad actions.
A recent analysis of published studies found that preoperative weight loss interventions do not significantly reduce post-surgical risks in obese patients. Lifestyle changes leading to modest weight loss have been shown to be ineffective in reducing morbidity and mortality during and after surgery.
A large-scale study found that bariatric surgery significantly reduces the risk of heart attacks, strokes, and deaths in individuals with type 2 diabetes and severe obesity. The study involved over 5,000 patients who underwent bariatric surgery compared to nearly 15,000 patients receiving usual medical care.
A recent study uses metabolome analysis to identify a link between metabolite changes and weight, revealing that genetics don't correlate closely with obesity. The research suggests new ways to measure obesity and health risks beyond traditional BMI measures.
Researchers developed a new method to use metabolites to predict diabetes and cardiovascular disease risk in people with obesity. The study analyzed over 2,400 participants and found that specific molecular signatures could identify individuals at higher risk of developing these diseases.
A large cohort of women under 50 showed a significant association between obesity and early onset colorectal cancer. Higher BMI, weight gain since age 18, and current body mass index were linked to increased risk of early onset CRC.
A high-fat diet in female mice affects their offspring's obesity, insulin resistance, and addictive-like behaviors for three generations. The study found that only females showed addictive-like behaviors, while males showed obesity characteristics in the third generation.
A new study found that young adults classified as obese in Australia can expect to lose up to 10 years of life expectancy. The study also predicts 36.3 million years of life will be lost due to overweight and obesity over the lifetime of today's Australian adult population.
Scientists have identified a molecular mechanism that leads overweight female rats to experience early-onset puberty. The study found that the SIRT1 enzyme plays a crucial role in transmitting body weight information to the brain, affecting the expression of the Kiss1 gene.
A new study found that listing calorie information on restaurant menus can lead to a significant decrease in the number of calories ordered. Participants who saw calorie counts listed first ordered food with an average of 24 percent fewer calories than those who saw them listed elsewhere.
Researchers identified a gene mutation linked to lower risk of diabetes, obesity, heart failure, and death. Selectively blocking the SGLT-1 receptor could slow down glucose uptake to prevent or treat cardiometabolic disease.
A Pennington Biomedical Research Center study found that female mice on a high-fat diet given Russian tarragon or bitter melon supplements gained more weight and body fat compared to those not receiving the supplements. However, there was no significant change in insulin sensitivity or body-fat percentages.
Researchers aim to uncover how altered signaling processes impact appetite regulation and obesity in mice, potentially leading to new therapeutic approaches for the condition. The grant could provide valuable insights into the complex communication pathways involved in brain obesity.
The CAMELLIA-TIMI 61 trial found that lorcaserin reduced the risk of diabetes by 19% in patients with pre-diabetes, induced remission in patients with diabetes, and reduced diabetic microvascular complications. Lorcaserin also significantly increased rates of diabetes remission and reduced the risk of severe hypoglycemia.
A new study published in The Lancet found that lorcaserin, an appetite-suppressant drug, decreases the risk of developing diabetes and increases the rates of remission of high blood sugar in obese and overweight patients. Lorcaserin also reduces the risk of kidney complications due to diabetes.
The study found large regional variations in diabetes prevalence, with North America and the Caribbean having high current rates, while Africa has low rates despite moderate obesity. If obesity rates are reduced by 25%, millions of cases of diabetes can be prevented, especially in Africa.
A study by USC Dornsife researchers found that an extra year of education contributed to weight loss in individuals at greatest risk of becoming obese. The study used genome data from 250,000 people and found that the change in mandatory attendance age had a significant impact on health outcomes.
Researchers found that obese patients who underwent a combined liver transplant and weight-loss surgery experienced significant weight loss maintenance and reduced metabolic complications. The study suggests that this dual approach is safe and effective over the long term for treating obesity-related liver disease.
A large observational study found that adults with type 2 diabetes are at greater risk of dying from cancer, particularly obesity-related cancers. Non-obesity related cancers also pose a significant threat to individuals with type 2 diabetes.
A new study reveals that gastric bypass surgery reduces all-cause mortality risk by 49% and cardiovascular disease risk by 34% in obese patients with type 2 diabetes. However, it also increases the risk of anaemia, malnutrition, and psychiatric diagnoses.
A simple measurement of abdominal obesity index (ABOI) has been developed to determine central obesity, focusing on abdominal fat content rather than total body weight or shape. ABOI can be calculated by measuring abdominal circumference and chest circumference, providing a more accurate assessment of abdominal obesity.
A new study found that a high-carbohydrate diet led to significant weight loss and improvements in insulin function in overweight individuals. The plant-based diet group consumed whole, complex carbohydrates from fruits, vegetables, and legumes, leading to reduced body mass index, body weight, and fat mass.
A new study shows Functional Imagery Training (FIT) significantly increases weight loss by 5 times compared to Motivational Interviewing (MI). Participants who used FIT lost an average of 4.11kg in six months and continued to lose weight after the intervention ended.
An analysis of published studies reveals that being overweight or obese is associated with a one-third increase in risk of urinary incontinence for young to mid-aged women. The risk is doubled in women with obesity. The findings suggest that lifestyle interventions may play a role in preventing and managing incontinence.
The USPSTF recommends intensive behavioral interventions focusing on dietary changes and increased physical activity for adults with a BMI of 30 or higher. Obesity is associated with increased risks of coronary heart disease, type 2 diabetes, various types of cancer, disability, and death, particularly among adults younger than 65 years.
The American College of Cardiology emphasizes that combating obesity in the US will require individual and societal changes to reduce cardiovascular risks. Implementing policy-level interventions, increasing physical activity, and promoting healthier diets are key aspects of this approach.
A new guideline published by the American Thoracic Society recommends weight loss strategies for adults with obstructive sleep apnea, particularly those who are overweight or obese. The guideline suggests comprehensive lifestyle interventions and behavioral counseling to help patients achieve weight loss.
Researchers found that patients who experienced a shift from sweet and fatty food preferences to bitter tastes after bariatric surgery lost the most weight. These altered preferences were temporary and generally returned to pre-surgery levels over time, but the majority of patients successfully maintained their weight loss.
A new study has found that people with asthma are more likely to become obese, especially if their asthma begins in adulthood or if they have non-allergic asthma. The research, which followed over 8,600 participants for two decades, suggests the relationship between asthma and obesity is more complex than previously thought.
A study by UC Riverside researchers found that male mice on high-fat diets experienced neuroinflammation and reduced testosterone levels, while female mice remained protected. The findings suggest ovarian estrogen plays a crucial role in protecting females against weight gain and associated health issues.
Researchers at Cincinnati Children's Hospital Medical Center genetically deleted Ago2 from the livers of mice, stabilizing energy metabolism and preventing obesity and diabetes. The study provides a solid basis for further research into novel therapeutic approaches to treat chronic metabolic disorders.
Research reveals obesity activates microglia, consuming healthy synapses and leading to dendritic spine loss. Microglial activity is causally linked to obesity-induced cognitive decline, suggesting a potential therapeutic target for this condition.
A study of black women found that those who slept less than 7 hours a night had higher blood pressure and lower levels of physical activity. The researchers suggest that addressing sleep quality is crucial for combating obesity and high blood pressure in this population.
Researchers discover gene H19 has a unique protective effect against the development of overweight and related diseases. Genes from mothers primarily lead to the development of brown fat tissue, which has a protective effect against obesity.
Researchers will evaluate the use of negative pressure wound therapy in obese and/or diabetic patients at five university-associated hospitals. The goal is to determine if this technique can help reduce incision site infections, a significant complication that can prevent proper wound healing and even lead to death.
Researchers at Université Laval found that camu camu phytochemicals prevent obesity in mice fed a diet rich in sugar and fat. The extract improved glucose tolerance, insulin sensitivity, and reduced inflammation, suggesting its potential as a natural weight management tool.
Researchers at TUM demonstrated that food increases thermogenesis in brown fat, contrary to the long-held assumption that it only responds to cold. This discovery could lead to new ways to prevent obesity and diabetes.
A new study found that obesity blunts post-workout muscle building and repair in young adults. The research showed that obese individuals had reduced rates of myofibrillar protein synthesis after a weightlifting session compared to normal-weight peers.
New research at McGill University found that people with higher BMI tend to have reduced cognitive flexibility, increased volume in the left amygdala and decreased volume in certain memory structures. The study suggests a model where genetics play a role in obesity through brain anatomy and cognitive functions.
Researchers argue that sugar is not responsible for obesity and metabolic diseases, citing evidence from multiple domains. Experts also highlight the importance of physical activity in determining metabolic health. The debate raises questions about the role of sugar in modern diets and whether restrictive recommendations are effective.
A study published in PLOS ONE found that restricting high-sucrose diet to active times reduced fat levels in rats. The research team limited the diet to nighttime, resulting in lower blood and liver fat compared to an unrestricted diet.
Researchers at Cedars-Sinai Medical Center have developed a simpler and more accurate method to estimate body fat percentage than the widely used BMI. The new relative fat mass index (RFM) formula uses only height and waist circumference measurements, providing a better measure of body fatness without requiring expensive equipment.
A recent study published in the New England Journal of Medicine found that lorcaserin, a weight loss drug, helped patients lose weight without increasing the incidence of heart attacks, strokes, and death from heart disease. The trial involved 12,000 overweight or obese patients at risk for cardiovascular events.
A team of researchers has discovered a molecular mechanism that causes leptin resistance in obese individuals, which blocks the brain's ability to recognize when it's full. By blocking this enzyme, MMP-2, scientists hope to develop treatments for obesity-related issues and explore its broader implications.
Scientists have identified a brain receptor protein that controls the body's 'fat rheostat', regulating energy balance and weight gain. The discovery opens new doors for developing anti-obesity drugs, particularly targeting the melanocortin 3 receptor (MC3R) to treat obesity.