Articles tagged with Obesity
Researchers discovered multiple genetic variants associated with body-fat tissue regulation and distribution. The findings broaden the understanding of how genes predispose individuals to obesity.
Researchers discovered a sex-specific obesity locus for the Lyplal1 gene, finding that females have a higher mitochondrial activity and produce more brown adipose tissue, reducing fat mass and insulin resistance. In contrast, males exhibit low mitochondrial activity and increased weight and insulin resistance.
Researchers from Mount Sinai will investigate the role of follicle-stimulating hormone (FSH) in regulating bone mass, body composition, and fat deposits during aging and menopause. The program aims to develop an FSH-blocking antibody for preventing and treating osteoporosis and obesity.
Researchers found that low-calorie diets can protect the brain from neuronal cell death associated with diseases such as Alzheimer's, Parkinson's, and cerebral vascular accident. Caloric restriction also improved insulin secretion and increased mitochondria efficiency in cells.
A new study reveals that obesity and inactivity significantly increase the risk of developing a walking disability after age 60. Older women are particularly vulnerable to this risk, highlighting the importance of an active lifestyle across all body weight categories.
Research suggests that low physical fitness, obesity, and a combination of both are strongly associated with chronic disability later in life. The study found that being physically fit is an important indicator of health regardless of BMI, reducing the risk of disability.
A study of 959 obese pregnant women found no significant difference in birth outcomes between early and routine gestational diabetes screening. Early screening was associated with increased insulin use, a potential drawback for patients.
A new study found that high-risk HPV infection is associated with an increased risk of cardiovascular disease (CVD), particularly among women with obesity or other cardiovascular risk factors. Women with high-risk HPV were 22% more likely to develop CVD, and those with obesity were nearly two-thirds more likely.
A recent study published in Diabetologia found that three-quarters of individuals with type 2 diabetes who underwent Roux-en-Y gastric bypass surgery experienced diabetes remission within one year. The research also identified predictors for success, including lower glycated haemoglobin levels and male patients, as well as a reduced ri...
Researchers found that clusterin protein is strongly related to insulin resistance, increased cardiovascular disease risk, and high blood pressure in obese patients. The study also linked clusterin to fatty liver disease and mortality.
A new study finds rates are increasing for six of 12 obesity-related cancers in younger adults in the US, with steeper increases in progressively younger ages. Excess body weight is a known carcinogen associated with more than a dozen cancers and suspected in several more.
Scientists at Helmholtz Munich found a transcription factor called Tbx3 that plays a pivotal role in maintaining energy and sugar metabolism. Its absence leads to an identity crisis of satiety neurons, resulting in obesity.
Researchers discovered 27 new molecules with significant therapeutic potential for treating fatty liver disease and obesity by activating the PPAR-delta protein. These molecules are currently undergoing pharmaceutical evaluations and show promise in improving physical endurance and reducing waistlines.
Researchers discovered that specific gut cells, intraepithelial T lymphocytes, limit the availability of hormones that speed up metabolism, leading to slowed metabolic rates and increased risk of obesity and cardiovascular disease. The study's findings could pave the way for new therapeutic avenues to treat related conditions.
Researchers at Johns Hopkins Medicine found that calorie restriction prevented asthma symptoms in mice, regardless of diet composition. The study's results add to evidence supporting links between obesity, inflammation, and asthma, highlighting the value of anti-inflammatory drugs in treating asthma symptoms in obese individuals.
Researchers at the University of Texas at Austin found that exercising regularly is linked to better eating habits, with participants more likely to choose foods like lean meats and fruits and vegetables after exercise.
A recent study published in the journal Nutrients found that vegan meals increased beneficial gastrointestinal hormones in individuals with obesity, type 2 diabetes, and healthy participants. This increase in gut hormones can help regulate blood sugar, enhance insulin secretion, promote satiety, and support weight management.
A study of 223 restaurant meals in six countries found 94% exceed recommended daily calorie intake. Popular meals like Brazil's rice and chicken dish contain up to 1656 kcal.
A study published in the Annals of the American Thoracic Society found that four grams of fish oil per day for six months did not improve asthma control in adolescents and young adults with uncontrolled asthma. The researchers suggested that obesity may cause systemic inflammation, which reduces the effectiveness of anti-inflammatory t...
For adolescents with obesity, weight loss medications may be an effective option that hasn't improved with lifestyle modification or surgery. Researchers recommend evidence-based guidance on medication use, emphasizing the importance of monitoring and further research.
A recent US study by UTSA researchers links food insecurity and living in a food desert to an increased risk of obesity. The study found that women are more likely to experience obesity due to food insecurity, while Black and Hispanic households face higher risks.
A new study published in the Journal of the Academy of Nutrition and Dietetics found that nearly a quarter of employed adults obtain high-calorie foods at work. The CDC investigated food acquisition habits through the Food Acquisition and Purchasing Survey, which revealed that these foods often don't align with the Dietary Guidelines f...
Researchers investigated the effect of AR inhibitor fidarestat on high-fat diet-induced intestinal polyps in ApcMin/+ mice. The study found that fidarestat reduced the number and size of polyps, as well as inhibited key proteins involved in carcinogenesis.
A new study models food consumption patterns by city block, finding that salad eaters and soda drinkers differ by socioeconomic status. Higher property values are associated with healthier diets, while lower values are linked to more soda consumption.
A study published in eNeuro found that neurons in the hippocampus inhibit future eating behavior by consolidating memories of preceding meals. The findings suggest that techniques promoting hippocampal-dependent memories could be promising strategies for reducing eating and promoting weight loss.
A study published by The Endocrine Society found that gastric bypass surgery improves relative muscle strength and physical performance in people with obesity. Despite dramatic weight loss causing a decline in absolute strength, patients experience meaningful improvements in walking speed and other measures of physical function.
A large-scale study published in Neurology found a significant link between excessive body fat around the middle and reduced brain volume, specifically lower gray matter volumes. Researchers measured BMI, waist-to-hip ratio, and overall body fat in 9,652 participants and found those with higher ratios had lower brain volume.
A Harvard University study found that the Coca-Cola Company, through its connection with a nonprofit group, has exerted substantial influence over obesity science and policy solutions in China. The study, conducted by Susan Greenhalgh, reveals how industry funding and personal connections shaped policy decisions.
Researchers at Rutgers University developed a way to reduce bleeding in patients after bariatric surgery. They found that endogenous thrombin potential (ETP) measurement provides a more accurate assessment of the best dosage for blood thinners, reducing the risk of minor and major bleeding.
An investigation by Susan Greenhalgh reveals how Coca-Cola influenced China's health policies through institutional, financial, and personal links. The company's focus on physical fitness over dietary restrictions has aligned with official obesity policy.
Research from Duke University suggests that context plays a significant role in food choices, with nearby indulgent treats leading to healthier options. The study found that when paired with unhealthy snacks, healthy foods became more appealing.
Older age, obesity, and depression were associated with chronic hip pain in a study of 2,515 adults. Chronic hip pain was found to be widespread in 50% of cases.
A new study using a mouse model found that pregnant mice fed a high-fat diet gained more body fat compared to control mice, but quickly lost the added weight after giving birth. However, they began gaining more fat again and weighed two-fold above levels of control mice due to excess fat mass.
After obesity surgery, new microbial strains emerged in the human fecal microbiota, changing the gut environment. The study used a novel informatics technique to identify these new strains, which were more competitive in the altered GI tract environment.
A new study published in Cell Metabolism suggests that energy balance - the calories consumed versus burned - may not determine the development of gestational diabetes. Women with obesity tend to develop gestational diabetes due to primary risk factors such as excess fat and insulin resistance, which can be evident early in pregnancy.
A study published in Obesity found that obese women who followed a diet with intermittent fasting lost more weight and improved their health compared to those who only restricted their diet or fasted intermittently. This research suggests that intermittent fasting may be an effective approach for improving obesity-related health outcomes.
A recent study from the University of Liverpool found that overweight dogs have a significantly shorter lifespan compared to those at ideal body weights. The study examined over 50,000 dogs across 12 breeds and revealed that being overweight can lead to poorer quality of life, joint disease, breathing issues, and certain types of cancer.
Research suggests that abdominal obesity may have evolved as a protective mechanism against infections in individuals who experienced poor fetal nutrition. This study proposes that the hallmark of obesity, visceral adipose tissue, provides immunity against abdominal infections.
A new study found that the proportion of cancers related to excess body weight varies greatly among US states, ranging from 5.9% in Hawaii to 8.3% in the District of Columbia. The study highlights the need for targeted interventions to reduce obesity and its associated cancer risks.
Aging endothelium displays reduced vasomotor functions and angiogenic capabilities due to increased oxidative stress. Lifestyle factors like exercise and omega-3 intake influence Endothelial Progenitor Cells (EPCs), which support endothelial health and function.
A recent study published in Journal of Radiological Protection found that severely obese patients require higher doses of radiation during X-rays to create images, increasing their cancer risk. The research, conducted on over 600 patients, showed a 153% increased risk of cancer compared to normal-weight individuals.
Women born with low birthweight are at increased risk of pregnancy complications, including preeclampsia and gestational hypertension. Those who were overweight or obese after pregnancy had even higher risks, highlighting the importance of modifiable lifestyle factors in reducing these risks.
A recent study found that food insecurity is associated with an increased likelihood of binge-eating disorder and obesity in US adults. Individuals with binge-eating disorder and obesity reported cutting meal sizes and skipping meals more frequently than those with a healthy weight.
Targeting chemical signals between the gut and brain may lead to a new treatment for obesity by disrupting nerve cells that send messages about food intake. Researchers found that nitric oxide reduces sensitivity of nerves, leading to increased food consumption in obese mice.
Researchers found that participants who completed mindfulness training lost an average of 3 kilograms more than those who did not attend the course. The study suggests that mindfulness techniques can help improve eating behavior and facilitate successful weight loss in individuals with obesity.
A new study published in Radiology found that MRI effective for monitoring liver fat levels in obese patients undergoing weight loss treatments. The study assessed liver fat before and after bariatric surgery using quantitative chemical shift-encoded MRI, showing a significant decrease in liver fat content after six to ten months.
Anxiety and depression are linked to increased odds for heart disease, high blood pressure, arthritis, stroke, but not cancer. Treating mental health conditions can cut healthcare costs, according to a new UCSF study.
Research suggests that a novel protein called Nischarin may be a promising therapeutic target for obesity and diabetes. Studies found that Nischarin expression is suppressed in fat tissue of obese humans and that its disruption leads to insulin resistance in female mice, but not male mice.
Researchers found that boys with better motor skills had higher cognitive scores over a two-year follow-up period. In contrast, aerobic fitness was not associated with cognitive function in either boys or girls.
A study analyzing 6,000 people found that tracking a patient's weight history from young adulthood can provide valuable insights into their future risk of heart failure. The investigation showed that maintaining a normal weight over the lifespan is ideal, while obesity at specific ages significantly increases the risk of heart disease.
A new study found that large, high-calorie portion sizes in fast food and full service restaurants are not unique to the US, affecting people globally. The research measured calorie content in popular meals from five countries and found that fast food meals contained fewer calories than full service meals.
New research found that ghrelin hormone makes people associate food odours with reward, leading to increased eating and obesity risk. Ghrelin also reduces response time and increases pleasantness of food images
A study published in Palgrave Communications found a strong negative correlation between median household income and obesity rates in the US. Since 1990, the rise of obesity has been fastest among the poorest regions, with lower-income households facing a higher likelihood of suffering from obesity and diabetes.
A recent study found that poverty and obesity are connected, with a significant increase in obesity rates among low-income households since the early 1990s. The correlation between household income and obesity rate has grown steadily over time, with the poorest counties experiencing the largest increases.
Researchers at Ben-Gurion University have improved a standard clinical scoring system to predict diabetic remission after bariatric surgery, extending prediction time from one to five years.
A first-of-its-kind study reveals high-intensity interval exercise can upregulate brain-derived neurotrophic factor (BDNF) expression in obese populations, potentially preventing cognitive dysfunction. The study also found that this type of exercise may be more effective than continuous moderate-intensity exercise.
A study found that obese patients with 'metabolically healthy obesity' had less deterioration in heart structure and function, leading to better survival rates. Metabolically healthy obese patients also had the best chance of survival compared to those with metabolic risk factors.
A new study found that underweight and morbidly obese individuals are at an elevated risk of hospitalization with influenza-like illness. The risk follows a 'U' shaped curve, indicating those at both extremes have a higher likelihood of developing severe symptoms.
A new study found that left gastric artery embolization, a weight loss procedure, not only reduces body fat but also leads to significant muscle mass loss. The researchers emphasized the need for proper nutritional counseling after the procedure to mitigate this risk.
A new study suggests that a molecule called BMP8b could be used as a drug to increase the amount of brown fat in humans and make it more active. In mice, increasing BMP8b levels changed some white fat into brown fat, leading to increased energy burn and lower risk of heart attack. Further research is needed to confirm its effectiveness.