Articles tagged with Obesity
A new study reveals that obesity and insulin resistance can break down the protective blood brain barrier in the brain, leading to problems with learning and memory. Blocking Adora2a receptors in a model of diet-induced obesity maintained barrier function, suggesting that controlling inflammation may prevent cognitive impairment.
Research suggests marijuana users are more likely to maintain a healthy weight compared to those who don't use cannabis. The study of over 33,000 participants found that persistent users were less likely to be overweight or obese.
Researchers have identified genetic variants in the MC4R gene that increase the activity of the brain receptor, providing protection against obesity and its complications. These variants may be used as models for developing new, safer weight loss therapies.
The study found that phenolic compounds in purple corn altered the development of fat cells and reduced inflammation and insulin resistance. Different combinations of anthocyanins showed varying effects on these biomarkers.
A study by University of Malaga researchers reveals that DNA methylation levels in genes related to lipid metabolism and inflammation are altered in obese patients with a metabolic disease. This dysregulation may contribute to the development of obesity-related diseases such as diabetes, cardiovascular disease, and cancer.
A study found that a newborn's first stool microbiome is linked to their risk of becoming overweight at age 3. Infants exposed to antibiotics during infancy had altered gut bacteria populations, which may contribute to long-term weight gain.
A longitudinal study found a correlation between ceramide levels, body mass index, and disease progression in MS patients. Individuals with higher ceramide levels experienced greater loss of motor skills and more brain injury over two years.
Research at the University of Liverpool found that people with obesity are stigmatized and explicitly considered to be less human than those without obesity. This blunt dehumanization was linked to support for health policies that discriminate against individuals due to their weight.
A new study published in Radiology found that bariatric embolization produces significant weight loss and reduces appetite for up to one year. The procedure involves blocking arteries with beads to suppress hunger-stimulating hormones. Researchers saw encouraging signs of metabolic changes, including improved quality of life.
Research from Rice University links digital device overload to obesity risk, finding media multitasking associated with increased susceptibility to food temptations and lack of self-control. The study suggests a possible link between media multitasking, higher body mass index, and greater percentage of body fat.
A new study published in CHEST finds that shortened sleep duration is independently associated with daytime sleepiness, while obstructive sleep apnea is linked to obesity, hypertension, and dyslipidemia. The study challenges traditional beliefs about the impact of sleep disorders on health.
Researchers create first highly potent and selective FKBP51 inhibitor to relieve chronic pain, promote weight loss and improve mood, with potential applications in alcoholism and brain cancer.
Researchers found that obesity at older ages is linked to worse outcomes, with higher tumor growth in obese mice compared to lean mice. They also discovered a connection between leptin, a biological signal released by fat tissue, and increased numbers of tumor-initiating cells.
A new CU Anschutz study found that physical activity is essential for maintaining substantial weight loss, rather than diet. Successful weight-loss maintainers engage in high levels of physical activity to prevent weight regain.
Men with hypogonadism and obesity who received long-term testosterone therapy achieved progressive and sustained weight loss, while untreated controls gained. Testosterone-treated men also experienced reductions in mortality and major cardiovascular events.
A new study suggests that white women with polycystic ovary syndrome (PCOS) experience higher levels of anxiety compared to their black counterparts. The research found a significant difference in anxiety symptoms between the two groups, with white women exhibiting higher rates of anxiety on screening tests.
A new study suggests that the adipose hormone aP2 is associated with obesity-related asthma and may be a key factor in its development. Higher levels of aP2 were found in people with overweight or obesity who also had asthma, suggesting a potential link between the two conditions.
A new study by The Endocrine Society found that treating obstructive sleep apnea (OSA) with an overnight CPAP machine can result in more weight loss for adults with obesity who try to lose weight by restricting calories. Patients who received concurrent CPAP treatment lost an average of 5.7 pounds more than those who did not treat thei...
A new study suggests that obesity may play a role in reproductive problems in women with type 1 diabetes. Menstrual irregularities were seen in 47% of those with the disease, and polycystic ovary syndrome (PCOS) was found in 14%, increasing the risk of miscarriages and stillbirths.
A new study presented at the Endocrine Society's annual meeting suggests that eating later in the day is associated with a higher body mass index and greater body fat. The research used advanced technology to track participants' sleep, physical activity, and eating patterns over a week-long period.
A study found that high-fructose corn syrup consumption enhances tumor growth in genetically predisposed mice with intestinal adenomas. The researchers discovered that HFCS leads to dramatic increases in tumor size and grade through altered metabolism, independent of obesity.
A new study by the University of Birmingham has found that high levels of testosterone and other androgens may cause a brain condition leading to blindness in women. The research, published in JCI Insight, suggests that female androgen excess may be a driver of abnormal brain pressure in people with idiopathic intracranial hypertension.
A new study published in the Journal of Public Health found that immigrant women in Norway are more likely to be overweight during pregnancy. The study, which analyzed data from 219,555 deliveries between 2006 and 2014, also found a significant association between country of birth and weight status.
A new report by University of Toronto researchers evaluates Canada's largest food and beverage companies based on their policies and commitments to sell healthier products. While many companies are making meaningful efforts to reduce sodium, sugar, and saturated fat in products, there is significant variability among them.
A University of East Anglia study found that individuals with a promotion focus tend to engage more in nutrition and exhibit greater knowledge of nutrition. This effect is stronger among high-income consumers, particularly men, suggesting targeted interventions can promote healthier habits.
A new study suggests that short-term strength training can improve liver health and blood sugar regulation in obese mice. The findings indicate that strength training may be a fast and effective strategy for reducing the risk of diabetes and fatty liver disease in obesity. However, further research is needed to confirm these results.
A new study published in the Journal of Nutritional Biochemistry found that green tea extract reduced weight gain and inflammation in mice fed a high-fat diet. The researchers also discovered improved gut health, including more beneficial microbes and less permeability in the intestinal wall. These findings suggest that green tea may h...
A Rutgers-led study found that higher doses of vitamin D improved memory and learning, but slowed reaction times among post-menopausal women. The researchers warn that excessive doses may compromise balance and walking ability, increasing the risk of falls.
A new mouse model shows enhancing lymph vessel formation via VEGF-D stimulation in obese adipose tissue has beneficial anti-inflammatory and metabolic effects. This approach may provide a new target for ameliorating the metabolic syndrome associated with obesity.
Researchers at the University of Illinois have found that free fatty acids in the blood promote proliferation and growth of breast cancer cells in obese women. The study suggests a potential link between obesity and an increased risk of ER-positive breast cancer after menopause.
A recent review study found that sit-stand desks can reduce sitting time and increase comfort, but physiological effects were mixed. To fully benefit from SSDs, workplaces need to understand proper usage and setup, including desk height, monitor height, and anti-fatigue mat use.
Researchers found that eating olive oil at least once a week was associated with lower platelet activation in obese adults. This could potentially reduce the risk of heart attacks and strokes in this population. However, more studies are needed to confirm these findings and establish causality.
Researchers at Rockefeller University have identified a genetic mechanism that may contribute to 10% of all obesity cases. Alterations in the cellular machinery regulating leptin production can lead to obesity treatable with leptin therapy, and human genetics studies suggest a similar mechanism may contribute to obesity in some patients.
A study of 936 asthma patients found that obesity and older age were linked to higher risks of airway closure. Therapies targeting airway closure may be crucial for these patients.
A randomized clinical trial examined two nutritional strategies: multinutrient supplementation and food-related behavioral activation therapy. The combination of both strategies showed promise in preventing new episodes of major depressive disorder among overweight and obese adults over one year.
An integrated therapy combining behavioral weight loss treatment and problem-solving therapy with antidepressant medication improved weight loss and depressive symptoms in patients with co-occurring obesity and depression. The study showed that participants receiving integrated therapy experienced a decline in body mass index and depre...
A study published in Nature Medicine reveals that celastrol increases brain sensitivity to leptin, leading to reduced food intake and weight loss. The research identifies a pro-inflammatory signaling pathway involving the IL1R1 receptor as key to understanding celastrol's effects.
Researchers found that people who were severely obese were 62 percent less likely to die after a stroke, compared to those of normal weight. The study also discovered that being overweight or obese may have a nutritional reserve that helps them survive during prolonged illness.
Research suggests a reciprocal relationship between obesity and self-control, with reduced prefrontal cortex activity leading to overeating and weight gain. Exercise and mindfulness can improve prefrontal cortex activity, promoting better dietary choices.
A study published in Scientific Reports identifies changes to neutrophils that increase vulnerability of obese and diabetic individuals to infection. Alterations to neutrophils, a type of white blood cell, lead to impaired activation of toll-like receptors (TLRs), weakening the immune system's ability to combat pathogens.
A new study published in Obesity found that successful weight losers spent an average of just 14.6 minutes per day on dietary self-monitoring, confirming the reality of its effectiveness rather than the perceived time-consuming nature. The most predictive factor was logging in three or more times a day with consistency.
A small Ohio State University study found a disconnect between Mexican immigrants' positive accounts of living in the US and their physical signs of stress, such as high blood pressure and obesity. The researchers believe these migrants use positive narratives to cope with discrimination and stress.
A new UNLV study finds that the quality of fruits and vegetables at dollar stores is comparable to traditional grocery store produce. The research team championed channel blurring, which benefits budget-conscious shoppers by increasing access to healthy, affordable food options.
A study of 4,818 patients found that diabetes, morbid obesity, tobacco smoking, and prolonged surgical duration increase the risk of surgical site infections. The overall incidence was 3.64%, with deep and superficial infections occurring at 0.4% and 1.1% respectively.
A new study from UC Berkeley finds that a soda tax led to a significant decrease in sugary drink consumption, with water consumption also increasing. The results suggest that taxes may be an effective tool in reducing sugar-linked diseases like diabetes and cardiovascular disease.
New research from the University of East Anglia found that lesbian and bisexual women are more likely to be overweight or obese compared to heterosexual women. Gay men, on the other hand, are less likely to be overweight but at risk of being underweight, which is linked to various health problems.
Researchers propose incorporating short high-intensity incidental physical activity (HIIPA) into daily routines to improve health. HIIPA involves brief bursts of high-intensity exercise, such as walking uphill or carrying groceries, which can be done in just a few minutes a day and offer significant health benefits.
Research finds that combining morning exercise with frequent breaks from sitting throughout the day significantly reduces systolic blood pressure in older overweight men and women. Women experience an enhanced benefit from this combination, which may be attributed to hormonal changes after menopause.
A new study has identified multiple genetic variants linked to how the body stores and distributes fat, paving the way for targeted interventions to reduce chronic illness risk. The findings also highlight the importance of lipid metabolism in body-fat distribution.
A study of over 30,000 Americans reveals significant differences in managing heart disease risk between women and men. Women have better control of high blood pressure, while both sexes struggle with obesity and cholesterol management.
Researchers discovered multiple genetic variants associated with body-fat tissue regulation and distribution. The findings broaden the understanding of how genes predispose individuals to obesity.
Researchers discovered a sex-specific obesity locus for the Lyplal1 gene, finding that females have a higher mitochondrial activity and produce more brown adipose tissue, reducing fat mass and insulin resistance. In contrast, males exhibit low mitochondrial activity and increased weight and insulin resistance.
Researchers from Mount Sinai will investigate the role of follicle-stimulating hormone (FSH) in regulating bone mass, body composition, and fat deposits during aging and menopause. The program aims to develop an FSH-blocking antibody for preventing and treating osteoporosis and obesity.
Researchers found that low-calorie diets can protect the brain from neuronal cell death associated with diseases such as Alzheimer's, Parkinson's, and cerebral vascular accident. Caloric restriction also improved insulin secretion and increased mitochondria efficiency in cells.
A new study reveals that obesity and inactivity significantly increase the risk of developing a walking disability after age 60. Older women are particularly vulnerable to this risk, highlighting the importance of an active lifestyle across all body weight categories.
Research suggests that low physical fitness, obesity, and a combination of both are strongly associated with chronic disability later in life. The study found that being physically fit is an important indicator of health regardless of BMI, reducing the risk of disability.
A study of 959 obese pregnant women found no significant difference in birth outcomes between early and routine gestational diabetes screening. Early screening was associated with increased insulin use, a potential drawback for patients.
A new study found that high-risk HPV infection is associated with an increased risk of cardiovascular disease (CVD), particularly among women with obesity or other cardiovascular risk factors. Women with high-risk HPV were 22% more likely to develop CVD, and those with obesity were nearly two-thirds more likely.
A recent study published in Diabetologia found that three-quarters of individuals with type 2 diabetes who underwent Roux-en-Y gastric bypass surgery experienced diabetes remission within one year. The research also identified predictors for success, including lower glycated haemoglobin levels and male patients, as well as a reduced ri...
Researchers found that clusterin protein is strongly related to insulin resistance, increased cardiovascular disease risk, and high blood pressure in obese patients. The study also linked clusterin to fatty liver disease and mortality.