Articles tagged with Obesity
Research suggests that obese females with high disinhibition scores have impaired metabolism and poorer outcomes due to poor insulin signaling. These women require weight loss treatment more urgently than those with low disinhibition scores.
Researchers have discovered a new biological pathway that connects anxiety and obesity, leading to the discovery of a potentially therapeutic drug. The study suggests that inhibiting an enzyme called PTP1B may alleviate both anxiety disorders and obesity.
A new study by the Endocrine Society finds that accumulating just 30 minutes of sleep debt on weekdays can lead to significant effects on obesity and insulin resistance at follow-up. The research suggests that avoiding sleep debt could have positive benefits for waistlines and metabolism.
Obesity in seniors is associated with increased hospitalizations, emergency room admissions, and outpatient healthcare use. The most severely obese group had 3.4 times the odds of inpatient admission and 1.4 times the odds of ER visit compared to healthy-weight individuals.
Researchers discover molecule found in tree leaves speeds up energy metabolism in female mice, but not in males. The findings suggest a promising strategy for combating obesity and highlight the need to study both sexes while developing drugs.
Researchers found altered opioid neurotransmission in obese individuals, with reduced opioid receptors in the brain. The study provides new insights into the mechanisms of overeating and obesity, but its findings do not indicate whether the changes are a cause or consequence of obesity.
Researchers at the University of Houston found a link between flame retardants and obesity in zebrafish exposed to compounds, suggesting these chemicals may contribute to weight gain. The study used zebrafish as a model organism to investigate the effects of two common flame retardants on body mass.
A recent study published in JAMA Pediatrics assessed cardiovascular risks among adolescents with severe obesity undergoing weight-loss surgery. The study found that nearly 95% of participants had at least one CVD risk factor, with high blood pressure and unhealthy cholesterol levels common among the group.
Researchers explore alternative methods to encourage healthy eating in children and teens, such as providing vegetables before other food options. Studies also investigate the impact of weight stigma, calorie counting, and food marketing on behavior, finding that weight stigma can lead to increased high-calorie snack consumption.
A study by Spanish scientists confirms that exposure to persistent organic pollutants in the body is linked to higher levels of cholesterol, triglycerides, and obesity. The researchers analyzed nearly 300 men and women and found a correlation between pollutant levels and health risks.
Research found that GLP-1 secretion is lower among people with pre-diabetes and obesity compared to normal weight individuals. The study suggests that early intervention with GLP-1 analogues may postpone the onset of type 2 diabetes.
Research suggests that heart failure patients who struggle with daily activities are at a higher risk of hospitalization and early death. The study found that older women, unmarried individuals, and those with chronic conditions such as obesity, dementia, anemia, and diabetes were more likely to experience these negative outcomes.
Researchers at UC San Diego found that LTB4 promotes insulin resistance in obese mice, but blocking the LTB4 receptor improves insulin sensitivity. Genetic deletion or drug inhibition of the receptor prevents and reverses type 2 diabetes in this model.
A new study by The Endocrine Society finds that low vitamin D levels are directly correlated with glucose metabolism, not just BMI. People with diabetes or prediabetes have lower vitamin D levels than those without these conditions.
A new study from the University of New Hampshire has found that flame retardants can cause metabolic and liver problems in laboratory rats, leading to insulin resistance. The researchers discovered that fat cells in these rats became more sensitive to hormones, similar to those experienced by people who are overweight.
A study led by Tokyo Medical University researcher Toshihiro Nakajima found that an anti-inflammatory drug can counteract obesity in mice by regulating mitochondrial biogenesis and fatty acid breakdown. The drug, LS-102, inhibits the Synoviolin gene, leading to increased energy control pathways.
A new study published in Diabetologia found that lack of sleep can lead to elevated levels of free fatty acids in the blood, causing temporary pre-diabetic conditions in healthy young men. Insufficient sleep also results in increased insulin resistance, a hallmark of pre-diabetes, that persists for nearly five hours.
A new study published in The Lancet emphasizes the need for improved healthcare systems to combat the growing obesity crisis. The study suggests that current clinical delivery systems are poorly suited for preventing and managing obesity, and that health professionals lack the training and tools needed to treat this condition. The auth...
A new approach to cardiovascular prevention is needed, integrating cardiac rehabilitation and secondary prevention. Fewer than half of coronary patients receive benefits from cardiac rehabilitation and preventive care.
Researcher Lora Cavuoto's study found that people who achieve weight loss or wellness success are more likely to influence their friends, while charismatic but unsuccessful individuals have a lower impact. This approach is taking precedence in new diet and exercise programs.
A new study by Regenstrief Institute and Indiana University finds that obese black and white women have distinct attitudes towards weight, with black women being more accepting of obesity. Despite differing views, neither group expressed a desire to lose weight or increase physical activity.
A leading group of obesity experts argues that obesity is a chronic disease with biological causes that cannot be cured by diet and exercise. Many people with obesity struggle to lose weight and regain it, as their bodies have adapted to conserve energy during times of food scarcity.
A new study by New York University and East China Normal University found that the design of the built environment significantly affects walking and bicycling in Chinese cities. The researchers discovered that neighborhoods with better urban design, such as wider sidewalks and bike lanes, had higher rates of physical activity.
A five-year follow-up study of patients with extreme obesity found that duodenal switch was more effective in reducing body weight than gastric bypass, but it came with a higher risk of complications. The study suggests that duodenal switch should be used with caution due to its adverse effects.
Researchers found that inhibiting molecular pathways involved in damage caused by stress response can improve egg viability. This approach may help obese women conceive using therapeutic approaches.
A study by Oregon State University found that treadmill desks increase physical activity but do not lead to significant weight loss or changes in Body Mass Index after 12 weeks. The employees only used the treadmills about half the time they were asked to, averaging one session and 45 minutes a day on the machines.
A primary care-based program has been shown to increase physical activity in overweight, middle-aged women, with improvements of up to 90 minutes per week compared to self-guided groups. The interventionist-led group also maintained higher levels of activity over time.
A team of researchers at the University of Wyoming found that adding capsaicin from chili peppers to a diet can stimulate energy metabolism and burn stored fat, potentially preventing obesity. The study used mice on high-fat diets and found that dietary capsaicin increased metabolic activity and energy expenditure.
A new study suggests that dark-colored grapes may help overweight people burn fat better by managing obesity-related metabolic disorders. Consuming grape extracts containing ellagic acid proved to boost metabolism of fatty acids and slow the growth of existing fat cells.
Researchers have identified a peptide called PACAP that reduces food intake and leads to weight loss when administered in the brain's central amygdala. The study suggests PACAP may be a target for medications treating obesity and binge-eating disorders.
A case report published in Open Forum Infectious Diseases reveals that a woman who underwent fecal microbiota transplant for a recurrent C. difficile infection rapidly gained weight, becoming obese. The study suggests that clinicians should avoid selecting stool donors who are overweight to minimize the risk of similar outcomes.
A recent study found that bariatric surgery increases life expectancy for most obese diabetic patients, but decreases it for those with very high body mass indexes. For patients with a BMI over 62, the benefit of surgery is minimal.
Research reveals that negative health messages are more effective for highly involved and detail-oriented audiences, while positive messages are better for those with uncertain outcomes. For the general public, positive messages with clear action steps are more effective.
A new study suggests that reversing brain inflammation caused by a high-fat diet greatly improves symptoms related to obesity and type II diabetes. Administering butein to obese mice improved glucose tolerance and brain insulin signalling, even at lower doses compared to non-treated mice.
A recent study published in Nature Communications found that the brain can regulate fat metabolism, potentially stopping the development of atherosclerosis and its associated risks. The researchers discovered that the brain uses the presence of fatty acids to trigger the liver to reduce its own lipid production.
A study of 212 bariatric surgery candidates found that 77.8% used the Internet to seek information about surgical procedures and patient experiences, while 92.6% trusted online advice before making a decision.
A new study found that oatmeal breakfast resulted in greater fullness and lower calorie intake at lunch compared to sugared corn flakes or water. The study suggested that the satiety effect of oatmeal may be due to its slower gastric emptying, which was more pronounced in overweight subjects.
A new Canadian guideline recommends measuring body mass index at primary health care visits to prevent and manage obesity. Structured behavioral interventions, including counseling, education, and environmental modifications, can help individuals lose weight, particularly those at high risk of diabetes.
The Endocrine Society recommends combining weight loss medications with diet and exercise, and considering bariatric surgery for those who have not achieved success. The guideline also provides recommendations for selecting medications that promote weight loss or have no effect on weight.
Researchers found that a fatty acid called myristoleic acid can help decode weight control by analyzing the lipidome, gene expression, and phenotype of obese women. This comprehensive insight may improve obesity management by understanding how adipose tissue responds to calorie restriction.
A new study published in the American Journal of Clinical Nutrition found that physical inactivity is responsible for twice as many deaths as obesity. The researchers analyzed data from over 334,000 European men and women and found that even a small increase in physical activity can have significant health benefits.
A Baylor University study reveals that more than a third of American clergy members are obese, with stress, longer hours, and being underpaid contributing factors. Clergy who take breaks, participate in support groups, or take sabbaticals tend to lower their obesity risk.
A study analyzing over 90,000 patient records found that few UK family doctors are treating obesity and overweight patients appropriately. Lifestyle change is the most common weight management plan offered, but progress on weight loss is often not tracked after an intervention has been introduced.
Researchers at the University of Michigan have identified how a promising drug, amlexanox, improves sugar metabolism by generating a new signal between fat cells and the liver. The findings suggest a new pathway for future treatments for obesity, diabetes, and fatty liver disease.
A new study published in the Journal of the American Heart Association found that a moderate fat diet incorporating one fresh avocado daily improved certain blood lipid markers, including total cholesterol to HDL and LDL-cholesterol ratios. The avocado diet achieved greater reductions in bad cholesterol levels compared to low-fat diets.
Research published in Springer's Obesity Surgery journal reveals that individuals who undergo weight-reducing bariatric surgery may face discrimination when interviewing for jobs. People are more likely to view someone who lost weight through exercise and dieting as more employable than one who had the procedure.
A new study by Ruopeng An found that smokers and the obese incur substantially higher annual health care costs compared to their peers. Out-of-pocket medical expenses, inpatient and outpatient care, emergency room visits, and prescription drugs contribute to these added expenditures.
A study found that bariatric surgery significantly reduced all-cause mortality rates among obese patients, with improved survival at 5 and 10 years post-surgery. The research involved 2,500 surgical patients and 7,462 control patients, and suggests a beneficial relationship between surgery and survival for severely obese adults.
A study of 2,500 obese patients and 7,500 matched controls found bariatric surgery reduces mortality risk by 53% at 5-14 years post-procedure. The surgery also became safer over time, with lower risk of death during and after the procedure.
Researchers have discovered new genetic and epigenetic factors that contribute to diabetes, suggesting a shared pathway between genes and environment. The study found similar epigenetic changes in fat cells of obese mice and humans, highlighting the consilience of genetics and environment.
A FDA-approved drug may help combat obesity by stimulating brown fat's metabolic activity, increasing resting metabolic rate, and promoting weight loss in rodents. Researchers discovered that mirabegron activates the beta-3 adrenergic receptor, a promising target for obesity treatment.
Researchers at Salk Institute develop a new compound called fexaramine that effectively stops weight gain, lowers cholesterol and controls blood sugar levels in mice. The pill tricks the body into thinking it has consumed calories, causing it to burn fat without altering appetite.
The study found that the Nordic diet reduced inflammation-associated gene expression in subcutaneous adipose tissue, even in overweight individuals. This suggests a possible link between diet and improved metabolic health.
Researchers found that γδ T cells contribute to systemic insulin resistance in obese mice by promoting low-grade inflammation in fat tissue. The study suggests that targeting γδ T cells may provide a new avenue for treating or preventing type 2 diabetes caused by obesity.
A 20-year study found that most healthy obese individuals progress to unhealthy obesity, highlighting the importance of weight management and treatment. The research also revealed a greater risk for cardiovascular disease in healthy obese adults compared to those with normal weight.
A study at Washington University School of Medicine found that a subset of obese individuals do not develop common metabolic abnormalities associated with obesity, such as insulin resistance and high blood pressure. In contrast, those who already had these problems worsened after gaining weight.
A new study reveals that genetic factors influencing obesity vary depending on the era of birth and when the research is conducted. Researchers found a stronger association between the FTO gene variant and obesity for individuals born after 1942 compared to those born before 1942.
Researchers found a significant impact of the FTO gene variant on body mass index (BMI) that largely depends on birth year, with stronger correlations in later years. The study suggests that broad environmental changes may alter the effect of the gene variant, highlighting the importance of considering time of birth in genetic studies.
A new study published in the Journal of the American College of Cardiology found that obese heart failure patients have better survival rates than normal-weight patients. Over a 10-year follow-up period, 38% of obese and 45% of overweight patients died compared to 51% of normal weight patients.
Researchers at the University of Rochester Medical Center discovered that the Thy1 protein plays a fundamental role in controlling whether primitive cells become fat cells. Restoring Thy1 expression may help prevent or reduce obesity.