Researchers found that a fatty acid called myristoleic acid can help decode weight control by analyzing the lipidome, gene expression, and phenotype of obese women. This comprehensive insight may improve obesity management by understanding how adipose tissue responds to calorie restriction.
A new study published in the American Journal of Clinical Nutrition found that physical inactivity is responsible for twice as many deaths as obesity. The researchers analyzed data from over 334,000 European men and women and found that even a small increase in physical activity can have significant health benefits.
A Baylor University study reveals that more than a third of American clergy members are obese, with stress, longer hours, and being underpaid contributing factors. Clergy who take breaks, participate in support groups, or take sabbaticals tend to lower their obesity risk.
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A study analyzing over 90,000 patient records found that few UK family doctors are treating obesity and overweight patients appropriately. Lifestyle change is the most common weight management plan offered, but progress on weight loss is often not tracked after an intervention has been introduced.
Researchers at the University of Michigan have identified how a promising drug, amlexanox, improves sugar metabolism by generating a new signal between fat cells and the liver. The findings suggest a new pathway for future treatments for obesity, diabetes, and fatty liver disease.
A new study published in the Journal of the American Heart Association found that a moderate fat diet incorporating one fresh avocado daily improved certain blood lipid markers, including total cholesterol to HDL and LDL-cholesterol ratios. The avocado diet achieved greater reductions in bad cholesterol levels compared to low-fat diets.
Research published in Springer's Obesity Surgery journal reveals that individuals who undergo weight-reducing bariatric surgery may face discrimination when interviewing for jobs. People are more likely to view someone who lost weight through exercise and dieting as more employable than one who had the procedure.
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A new study by Ruopeng An found that smokers and the obese incur substantially higher annual health care costs compared to their peers. Out-of-pocket medical expenses, inpatient and outpatient care, emergency room visits, and prescription drugs contribute to these added expenditures.
A study found that bariatric surgery significantly reduced all-cause mortality rates among obese patients, with improved survival at 5 and 10 years post-surgery. The research involved 2,500 surgical patients and 7,462 control patients, and suggests a beneficial relationship between surgery and survival for severely obese adults.
A study of 2,500 obese patients and 7,500 matched controls found bariatric surgery reduces mortality risk by 53% at 5-14 years post-procedure. The surgery also became safer over time, with lower risk of death during and after the procedure.
Researchers have discovered new genetic and epigenetic factors that contribute to diabetes, suggesting a shared pathway between genes and environment. The study found similar epigenetic changes in fat cells of obese mice and humans, highlighting the consilience of genetics and environment.
A FDA-approved drug may help combat obesity by stimulating brown fat's metabolic activity, increasing resting metabolic rate, and promoting weight loss in rodents. Researchers discovered that mirabegron activates the beta-3 adrenergic receptor, a promising target for obesity treatment.
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Researchers at Salk Institute develop a new compound called fexaramine that effectively stops weight gain, lowers cholesterol and controls blood sugar levels in mice. The pill tricks the body into thinking it has consumed calories, causing it to burn fat without altering appetite.
The study found that the Nordic diet reduced inflammation-associated gene expression in subcutaneous adipose tissue, even in overweight individuals. This suggests a possible link between diet and improved metabolic health.
Researchers found that γδ T cells contribute to systemic insulin resistance in obese mice by promoting low-grade inflammation in fat tissue. The study suggests that targeting γδ T cells may provide a new avenue for treating or preventing type 2 diabetes caused by obesity.
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A 20-year study found that most healthy obese individuals progress to unhealthy obesity, highlighting the importance of weight management and treatment. The research also revealed a greater risk for cardiovascular disease in healthy obese adults compared to those with normal weight.
A study at Washington University School of Medicine found that a subset of obese individuals do not develop common metabolic abnormalities associated with obesity, such as insulin resistance and high blood pressure. In contrast, those who already had these problems worsened after gaining weight.
A new study reveals that genetic factors influencing obesity vary depending on the era of birth and when the research is conducted. Researchers found a stronger association between the FTO gene variant and obesity for individuals born after 1942 compared to those born before 1942.
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Researchers found a significant impact of the FTO gene variant on body mass index (BMI) that largely depends on birth year, with stronger correlations in later years. The study suggests that broad environmental changes may alter the effect of the gene variant, highlighting the importance of considering time of birth in genetic studies.
A new study published in the Journal of the American College of Cardiology found that obese heart failure patients have better survival rates than normal-weight patients. Over a 10-year follow-up period, 38% of obese and 45% of overweight patients died compared to 51% of normal weight patients.
Researchers at the University of Rochester Medical Center discovered that the Thy1 protein plays a fundamental role in controlling whether primitive cells become fat cells. Restoring Thy1 expression may help prevent or reduce obesity.
A study of nearly 15,000 middle-aged men and women found that those with the highest waist-to-hip ratio were twice as likely to experience sudden cardiac death as those with a normal ratio. The risk was strongly associated with central obesity, particularly around the midriff, which is thought to contribute to inflammation.
Researchers found that potato extract reduced weight gain in mice fed an obesity-inducing diet by 9 grams. The extract's high polyphenol content is responsible for its benefits. This study suggests that potato extracts could be a low-cost solution for preventing both obesity and type 2 diabetes.
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Researchers found that weight loss surgery in obese individuals can reduce lower urinary tract symptoms, including increased frequency and urgency. The improvement is linked to improved insulin sensitivity, indicating a reduced risk of developing type 2 diabetes.
Researchers have successfully designed a substance combining three metabolically active hormone components (GLP-1, GIP, and glucagon) to fight metabolic diseases. The triple hormone reduces body weight by around 30 percent while improving insulin sensitivity, essentially curing obesity and diabetes in animal models.
A new peptide developed by IU researchers has effectively cured lab animals of obesity, diabetes, and associated lipid abnormalities. The peptide combines the properties of three gastrointestinal hormones, GLP-1, GIP, and glucagon, and has shown unprecedented efficacy in reducing body weight and controlling metabolism.
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Researchers discovered that the intestinal immune system controls energy metabolism and can modify intestinal bacteria to prevent obesity and diabetes. By disabling a protein called MyD88, the team showed that mice can lose weight and reduce inflammation.
A study found that a sugary diet before mating triggers obesity in offspring, while certain gene networks predict susceptibility to weight gain. The researchers also identified similar mechanisms in humans and mice.
A study found that high sugar diets in male fruit flies can cause obesity in their offspring through epigenetic changes affecting gene expression. Researchers also discovered a similar system regulating obesity susceptibility in mice and humans.
A groundbreaking study by Australian researchers has discovered that leptin hormone secreted by fat cells elevates blood pressure in obesity. The hormone acts in the brain to increase blood pressure, making it a promising target for treating obesity-induced hypertension and cardiovascular diseases.
A study published in Cell found that leptin, the 'satiety hormone', is linked to obesity-induced high blood pressure. Researchers discovered that obese individuals lacking leptin or its receptor had lower blood pressure despite being heavy.
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A study published in The Lancet Diabetes & Endocrinology found that obesity is associated with a dramatic increase in risk of developing type 2 diabetes and cardiovascular disease. As a result, adults who are overweight or obese may lose up to 19 years of healthy life, while those who are very obese may lose up to 8 years.
A new study published in The Lancet Diabetes and Endocrinology found that obesity can decrease life expectancy by up to 8 years. Researchers used data from the National Health and Nutrition Examination Survey to develop a model estimating annual risk of diabetes and cardiovascular disease in adults with different body weights.
Researchers found that time-restricted eating can prevent metabolic problems and halt disease progression, even with occasional
Millions die each year from obesity-related issues, with Australia projected to be third fattest nation by 2020. Fitness facilities can mitigate risks by implementing pre-activity screening, automated defibrillators, regular inspections, and staff training.
Researchers at Salk Institute discover that confining caloric consumption to an 8- to 12-hour period can significantly reduce weight gain, improve body composition, and even reverse obesity and diabetes in mice. The study's findings add to mounting evidence highlighting the importance of time-restricted eating for overall health.
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A component of the plant Glycyrrhiza uralensis has been shown to inhibit the development of metabolic disorders by stopping the activation of NLRP3, a protein involved in disease process. Isoliquiritigenin attenuates high-fat diet-induced obesity, type 2 diabetes and hepatic steatosis in mice.
A new study reveals that exercise following gastric bypass surgery provides additional benefits for obese patients, including improved insulin sensitivity and cardiovascular fitness. This clinical trial supports the inclusion of an exercise program after bariatric surgery to enhance overall health outcomes.
Research warns that bariatric surgery patients who don't take their prescribed supplements, especially Vitamin A, are at risk of eye-related complications such as night blindness and dry eyes. Vitamin A deficiency can lead to severe consequences like total blindness if left undetected.
Researchers found that excessive contact between cellular organelles disrupts metabolism in obesity, leading to insulin resistance and diabetes. Disrupting these connections improved metabolic health in obese diabetic mice, pointing to a potential treatment target.
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A study by Columbia University's Mailman School of Public Health estimates that obesity-attributable absenteeism among US workers costs the nation more than $8 billion annually, with state-level costs ranging from $14.4 million in Wisconsin to $907 million in California.
A study found that obesity causes subclinical heart muscle injury and increases the risk for heart failure, even in people without overt heart disease. Obesity was independently associated with increased troponin levels, a marker of heart damage.
A study found that children who spend more time in front of screens are at increased risk for obesity and heart disease. The researchers suggest reducing parental screen time may help lower the risk in children. Parents' behavior can have a lasting impact on their child's health.
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A new study by Women's College Hospital found South Asian boys are three times as likely to be overweight compared to their peers. The research measured the heights and weights of over 700 Toronto students between ages 10-12 and tracked physical activity, socio-demographic factors.
Researchers at the University of Michigan discovered a new hormone called NRG4 that serves as a messenger from fat cells to the liver, regulating sugar conversion into fat. Mice with elevated NRG4 levels were protected from metabolic disorders, suggesting its potential as a treatment for obesity and related diseases.
Researchers found that smartphone apps designed for weight loss were unlikely to produce substantial weight loss in obese patients, highlighting the need for more engaging and time-efficient tools. Meanwhile, a study showed that offering a one-in-ten chance of winning $50 increased colon cancer screening rates by 20% compared to other ...
A majority of obese people in Britain deny being obese, describing themselves as 'just right' or 'very overweight' instead. The study suggests that media coverage and public health campaigns may be contributing to this phenomenon, as people become less likely to recognize the health risks associated with their weight.
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Researchers found that mice eat less when their liver stores high levels of glucose, suggesting a link between the liver and brain in regulating appetite. The study's findings could lead to new therapeutic targets for improving diabetes and obesity.
A study found that middle-aged men whose parents were older at birth had lower blood pressure, more favorable cholesterol levels, and improved glucose metabolism. Further research is needed to determine the causes of this effect, with epigenetics and post-natal factors being potential explanations.
A new study suggests that individuals with more severe asthma may be more motivated to lose weight, making them a key target for intervention. Gender tailoring of weight loss programs could also enhance success rates among adults with asthma.
A new study found that false beliefs about weight loss pills lead to overeating and unhealthy behavior. The study suggests that consumers who believe in the effectiveness of weight loss pills consume more cookies when given free access.
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A new study found that fast-food outlets within 500m of non-white ethnic minority groups and socially deprived areas are associated with increased risk of Type-2 diabetes and obesity. The research suggests that for every two additional fast-food outlets, one extra diabetes case can be expected.
A new study found that restaurant surcharges and labeling can reduce demand for unhealthy menu items. The study showed that customers are more likely to avoid unhealthy food with a label and a surcharge than without either. This combination is called an 'unhealthy surcharge' and may lead to increased customer trust and loyalty
A team of researchers has drawn connections between known regulators of body mass, pointing to possible treatments for obesity and metabolic disorders. They also found intriguing clues that these same molecular pathways may play a role in learning and perhaps even in some forms of brain cancer.
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A recent Tel Aviv University study found that obesity leads to a breakdown of the body's protective self-tolerance, creating an environment for autoimmune diseases. The research also highlights the importance of vitamin D supplements in alleviating symptoms and improving prognosis for patients with multiple sclerosis.
A systematic review found that high-quality randomized controlled trials on behavioral weight loss counseling in primary care settings are limited, with only two studies identifying effective interventions producing an average weight loss of at least five percent. The review highlights the need for further research to evaluate the effe...
The Texas A&M AgriLife Extension Service has received a $783,000 grant to support national efforts to reduce chronic diseases and promote healthier lifestyles. The program will focus on improving access to healthy foods and safe locations for physical activity in Hidalgo County.
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Researchers at UC Davis found that immunotherapy regimens can be lethal to obese mice due to increased body fat, which affects the immune system's response. The study suggests a link between obesity and toxicity in cancer treatment outcomes.
A Canadian study found that men, seniors, and smokers are among the most likely to forego bariatric surgery, despite not being turned away due to payment. Researchers are now exploring why these patients drop out to improve operational efficiency and provide proper support.
A new study published in The Lancet Diabetes & Endocrinology found that bariatric surgery can reduce the risk of developing type 2 diabetes by around 80% in obese people compared to standard care. This significant reduction was observed even after controlling for other important factors such as smoking and high blood pressure.
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