Articles tagged with Obesity
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A new study found that medication for type II diabetes activates sensors on brain cells, increasing hunger and leading to weight gain. Researchers at Georgia State University discovered the role of peroxisome proliferator-activated receptor Upsih (PPAR&Upsih) sensors in controlling eating behavior.
A study from the University of Eastern Finland found that risk factor levels even below accepted thresholds can be harmful when several risk factors cluster. Clustered risk factors were linked to elevated liver enzymes in overweight children, particularly those with a common PNPLA3 gene mutation.
Scientists developed a new way to cook rice that increases resistant starch content, potentially reducing calories absorbed by the body by over half. This simple cooking method can transform digestible starch into indigestible resistant starch, lowering usable calories and addressing obesity rates.
Researchers have programmed bacteria to generate a hunger-suppressing lipid, leading to reduced body fat and staved-off diabetes in mice. The therapeutic bacteria could provide sustained drug delivery, potentially improving weight loss outcomes for humans.
A new RAND Corporation study reveals that Los Angeles' fast-food ban has failed to improve diets or reduce obesity rates in low-income areas. Despite the ban, fast-food consumption increased and obesity rates rose faster than in other parts of the city.
Researchers found that visual cues associated with overweight people influence one's sense of smell, and participants with higher BMI tend to be more critical of heavier individuals. This study suggests that weight stigma may be more pervasive than previously thought, affecting everyday life in various ways.
A study of 503 Mexican-Americans found that nearly 78% were metabolically unhealthy, with a high prevalence of cardiometabolic risk factors. The research suggests that metabolic risk has a greater effect on developing atherosclerosis, regardless of obesity status.
Research suggests that too much artificial light in the evening can disrupt the body's circadian rhythm and lead to health problems such as breast cancer, obesity, diabetes, and depression. Experts recommend using devices with dimmer, longer wavelengths of light in the evening to minimize disruption.
A study published in the Journal of the American Geriatrics Society found that diet soda intake is directly linked to greater abdominal obesity in adults 65 years of age and older. Increasing waist circumference was associated with escalating cardiometabolic risk in older adults.
A study led by Massachusetts General Hospital investigators suggests that bariatric surgery can significantly reduce the risk of asthma attacks in obese patients. Significant weight reduction after surgery resulted in a half reduction in serious asthma-associated events, including emergency department visits and hospitalizations.
A new study from Brigham Young University finds that loneliness and social isolation are major risk factors for mortality across all ages and income levels. The research analyzed data from over 3 million participants and found that the lack of social connections presents an added risk, while the existence of relationships provides a po...
A review of nutrition and weight-loss interventions found a gap in approaches for people with neurological disabilities, who struggle to lose weight due to limited mobility. The study identified 27 behavior-changing techniques targeting weight-loss for people with disabilities, including self-monitoring and managing time.
A study by Deakin University found that many Australian online health information is too difficult to read, leading to potential misinterpretation and inappropriate healthcare decisions. The researchers suggest that websites need to be assessed for readability and changes made to improve accessibility.
A new study reveals that mucosal-associated invariant T (MAIT) cells are dramatically reduced in individuals with type 2 diabetes and severe obesity, yet abundant in adipose tissue. MAIT cell abnormalities may contribute to obesity-associated metabolic alterations after weight loss restored circulating MAIT cells.
A study from Thailand finds that 56% of pregnant women with diet-controlled gestational diabetes have obstructive sleep apnea. The severity of sleep disordered breathing is associated with higher blood glucose levels and greater daytime sleepiness, highlighting the importance of OSA diagnosis in this population.
A new experimental drug, GC-1, has been found to convert 'bad' white fat into 'good' brown-like fat, leading to weight loss and improved insulin sensitivity in mice. Researchers believe this conversion may help treat obesity and metabolic disease.
A recent study found that patients on liraglutide achieved at least 5% weight loss, showing improvements in health markers, blood sugar control, and blood pressure. The results suggest liraglutide as a treatment option for obesity with significant health benefits.
A new study shows that letrozole at a low dose can normalize testosterone levels and sperm production in obese men with infertility. The treatment led to successful pregnancies and births in three couples, offering a promising new hope for male infertility treatments.
A new study found that gastric bypass surgery in adolescents significantly improved bone density, which returned to normal levels within two years. The results suggest that obesity surgery may have favorable effects on the adolescent skeleton.
A new study suggests that mindfulness-based stress reduction (MBSR) can decrease fasting glucose levels and improve quality of life in overweight and obese women. MBSR significantly reduces perceived stress and improves sleep, depression, anxiety, and psychological distress without changing body weight or insulin resistance.
A study of 200 adult men with borderline testosterone levels found that 56% had significant depressive symptoms, highlighting the need for clinicians to manage comorbidities like depression and obesity in this population. The researchers also noted a high prevalence of overweight, obesity, and physical inactivity among participants.
Research suggests that obese females with high disinhibition scores have impaired metabolism and poorer outcomes due to poor insulin signaling. These women require weight loss treatment more urgently than those with low disinhibition scores.
Researchers have discovered a new biological pathway that connects anxiety and obesity, leading to the discovery of a potentially therapeutic drug. The study suggests that inhibiting an enzyme called PTP1B may alleviate both anxiety disorders and obesity.
A new study by the Endocrine Society finds that accumulating just 30 minutes of sleep debt on weekdays can lead to significant effects on obesity and insulin resistance at follow-up. The research suggests that avoiding sleep debt could have positive benefits for waistlines and metabolism.
Obesity in seniors is associated with increased hospitalizations, emergency room admissions, and outpatient healthcare use. The most severely obese group had 3.4 times the odds of inpatient admission and 1.4 times the odds of ER visit compared to healthy-weight individuals.
Researchers discover molecule found in tree leaves speeds up energy metabolism in female mice, but not in males. The findings suggest a promising strategy for combating obesity and highlight the need to study both sexes while developing drugs.
Researchers found altered opioid neurotransmission in obese individuals, with reduced opioid receptors in the brain. The study provides new insights into the mechanisms of overeating and obesity, but its findings do not indicate whether the changes are a cause or consequence of obesity.
Researchers at the University of Houston found a link between flame retardants and obesity in zebrafish exposed to compounds, suggesting these chemicals may contribute to weight gain. The study used zebrafish as a model organism to investigate the effects of two common flame retardants on body mass.
A recent study published in JAMA Pediatrics assessed cardiovascular risks among adolescents with severe obesity undergoing weight-loss surgery. The study found that nearly 95% of participants had at least one CVD risk factor, with high blood pressure and unhealthy cholesterol levels common among the group.
Researchers explore alternative methods to encourage healthy eating in children and teens, such as providing vegetables before other food options. Studies also investigate the impact of weight stigma, calorie counting, and food marketing on behavior, finding that weight stigma can lead to increased high-calorie snack consumption.
A study by Spanish scientists confirms that exposure to persistent organic pollutants in the body is linked to higher levels of cholesterol, triglycerides, and obesity. The researchers analyzed nearly 300 men and women and found a correlation between pollutant levels and health risks.
Research found that GLP-1 secretion is lower among people with pre-diabetes and obesity compared to normal weight individuals. The study suggests that early intervention with GLP-1 analogues may postpone the onset of type 2 diabetes.
Research suggests that heart failure patients who struggle with daily activities are at a higher risk of hospitalization and early death. The study found that older women, unmarried individuals, and those with chronic conditions such as obesity, dementia, anemia, and diabetes were more likely to experience these negative outcomes.
Researchers at UC San Diego found that LTB4 promotes insulin resistance in obese mice, but blocking the LTB4 receptor improves insulin sensitivity. Genetic deletion or drug inhibition of the receptor prevents and reverses type 2 diabetes in this model.
A new study by The Endocrine Society finds that low vitamin D levels are directly correlated with glucose metabolism, not just BMI. People with diabetes or prediabetes have lower vitamin D levels than those without these conditions.
A new study from the University of New Hampshire has found that flame retardants can cause metabolic and liver problems in laboratory rats, leading to insulin resistance. The researchers discovered that fat cells in these rats became more sensitive to hormones, similar to those experienced by people who are overweight.
A study led by Tokyo Medical University researcher Toshihiro Nakajima found that an anti-inflammatory drug can counteract obesity in mice by regulating mitochondrial biogenesis and fatty acid breakdown. The drug, LS-102, inhibits the Synoviolin gene, leading to increased energy control pathways.
A new study published in Diabetologia found that lack of sleep can lead to elevated levels of free fatty acids in the blood, causing temporary pre-diabetic conditions in healthy young men. Insufficient sleep also results in increased insulin resistance, a hallmark of pre-diabetes, that persists for nearly five hours.
A new study published in The Lancet emphasizes the need for improved healthcare systems to combat the growing obesity crisis. The study suggests that current clinical delivery systems are poorly suited for preventing and managing obesity, and that health professionals lack the training and tools needed to treat this condition. The auth...
A new approach to cardiovascular prevention is needed, integrating cardiac rehabilitation and secondary prevention. Fewer than half of coronary patients receive benefits from cardiac rehabilitation and preventive care.
Researcher Lora Cavuoto's study found that people who achieve weight loss or wellness success are more likely to influence their friends, while charismatic but unsuccessful individuals have a lower impact. This approach is taking precedence in new diet and exercise programs.
A new study by Regenstrief Institute and Indiana University finds that obese black and white women have distinct attitudes towards weight, with black women being more accepting of obesity. Despite differing views, neither group expressed a desire to lose weight or increase physical activity.
A leading group of obesity experts argues that obesity is a chronic disease with biological causes that cannot be cured by diet and exercise. Many people with obesity struggle to lose weight and regain it, as their bodies have adapted to conserve energy during times of food scarcity.
A new study by New York University and East China Normal University found that the design of the built environment significantly affects walking and bicycling in Chinese cities. The researchers discovered that neighborhoods with better urban design, such as wider sidewalks and bike lanes, had higher rates of physical activity.
A five-year follow-up study of patients with extreme obesity found that duodenal switch was more effective in reducing body weight than gastric bypass, but it came with a higher risk of complications. The study suggests that duodenal switch should be used with caution due to its adverse effects.
Researchers found that inhibiting molecular pathways involved in damage caused by stress response can improve egg viability. This approach may help obese women conceive using therapeutic approaches.
A study by Oregon State University found that treadmill desks increase physical activity but do not lead to significant weight loss or changes in Body Mass Index after 12 weeks. The employees only used the treadmills about half the time they were asked to, averaging one session and 45 minutes a day on the machines.
A primary care-based program has been shown to increase physical activity in overweight, middle-aged women, with improvements of up to 90 minutes per week compared to self-guided groups. The interventionist-led group also maintained higher levels of activity over time.
A team of researchers at the University of Wyoming found that adding capsaicin from chili peppers to a diet can stimulate energy metabolism and burn stored fat, potentially preventing obesity. The study used mice on high-fat diets and found that dietary capsaicin increased metabolic activity and energy expenditure.
A new study suggests that dark-colored grapes may help overweight people burn fat better by managing obesity-related metabolic disorders. Consuming grape extracts containing ellagic acid proved to boost metabolism of fatty acids and slow the growth of existing fat cells.
Researchers have identified a peptide called PACAP that reduces food intake and leads to weight loss when administered in the brain's central amygdala. The study suggests PACAP may be a target for medications treating obesity and binge-eating disorders.
A case report published in Open Forum Infectious Diseases reveals that a woman who underwent fecal microbiota transplant for a recurrent C. difficile infection rapidly gained weight, becoming obese. The study suggests that clinicians should avoid selecting stool donors who are overweight to minimize the risk of similar outcomes.
A recent study found that bariatric surgery increases life expectancy for most obese diabetic patients, but decreases it for those with very high body mass indexes. For patients with a BMI over 62, the benefit of surgery is minimal.
Research reveals that negative health messages are more effective for highly involved and detail-oriented audiences, while positive messages are better for those with uncertain outcomes. For the general public, positive messages with clear action steps are more effective.
A new study suggests that reversing brain inflammation caused by a high-fat diet greatly improves symptoms related to obesity and type II diabetes. Administering butein to obese mice improved glucose tolerance and brain insulin signalling, even at lower doses compared to non-treated mice.
A recent study published in Nature Communications found that the brain can regulate fat metabolism, potentially stopping the development of atherosclerosis and its associated risks. The researchers discovered that the brain uses the presence of fatty acids to trigger the liver to reduce its own lipid production.
A study of 212 bariatric surgery candidates found that 77.8% used the Internet to seek information about surgical procedures and patient experiences, while 92.6% trusted online advice before making a decision.
A new study found that oatmeal breakfast resulted in greater fullness and lower calorie intake at lunch compared to sugared corn flakes or water. The study suggested that the satiety effect of oatmeal may be due to its slower gastric emptying, which was more pronounced in overweight subjects.
A new Canadian guideline recommends measuring body mass index at primary health care visits to prevent and manage obesity. Structured behavioral interventions, including counseling, education, and environmental modifications, can help individuals lose weight, particularly those at high risk of diabetes.
The Endocrine Society recommends combining weight loss medications with diet and exercise, and considering bariatric surgery for those who have not achieved success. The guideline also provides recommendations for selecting medications that promote weight loss or have no effect on weight.