Articles tagged with Obesity
Scientists design a peptide that binds to ghrelin and Y2 receptors, reducing appetite in obese mice. The compound shows promise as an obesity treatment targeting the complex system of hormones regulating appetite.
A new NIH study reveals that people with certain physiologies lose less weight when limiting calories. Those with a 'thrifty' metabolism, characterized by decreased energy expenditure during fasting, tend to lose less weight during calorie-reduced periods.
A new study published in the American Journal of Preventive Medicine found that people who moved to more socioeconomically deprived neighborhoods gained additional weight. The study used data from over 3,000 Dallas County residents and found a significant association between moving to a higher-NDI neighborhood and increased weight gain.
Researchers found that using a shopping list was associated with improved dietary quality and lower weight among low-income participants living in food deserts. The study suggests that this simple tool can be an effective way to promote healthy eating habits and reduce health risks.
Researchers discovered IRF5 helps prevent metabolic complications by storing fat subcutaneously. In contrast to intra-abdominal fat, which leads to type 2 diabetes, this storage form reduces inflammation and promotes tissue remodelling.
Researchers found obesity and depression to be underlying causes of regular drowsiness, with low-grade chronic inflammation a primary mechanism for fatigue in obese individuals. Depressed individuals also experienced high incidence of EDS, likely due to physiologic sleep disturbances.
A recent study has identified the enzyme responsible for obesity-related hypertension, which breaks down a molecule necessary for relaxing blood vessels. The research suggests that targeting this enzyme may lead to new treatment options for obese patients with high blood pressure.
A meta-analysis found intragastric injection of botulinum toxin A effective for treating obesity, with significant weight loss in treated patients compared to placebo. Additionally, a study concluded that flexible endoscopes can be stored for up to 21 days after reprocessing without microbial colonization
Research found that patients with type 2 diabetes who are overweight but not obese live longer than those who are underweight or normal-weight. The 'obesity paradox' suggests that excess weight may be beneficial for survival in these patients, contrary to previous expectations. Meanwhile, daily low-molecular-weight heparin injections w...
A study found that obese patients undergoing common cosmetic plastic surgery procedures had higher rates of complications, hospital visits, and emergency department visits. The findings link obesity to increased healthcare costs, with average cost differences ranging from $3,900 to $7,400.
A study by Imperial College London identifies chemical markers in urine associated with body mass, providing insights into how obesity causes disease. The findings suggest that obesity has a 'metabolic signature' detectable in urine samples, pointing to processes that could be targeted to mitigate its effects.
A new study reveals a significant gender gap in bariatric surgery rates among U.S. men and women. Demographic, socioeconomic and cultural factors contribute to the disparity, with men undergoing surgeries at lower rates than women.
A study by Ohio State University found that people with low self-esteem related to their weight are more likely to have visible food in their homes, eat unhealthy foods, and experience depression. The home environment may contribute to obesity, but it's not a clear cause-and-effect relationship.
A new genetic mutation in the GLP1R gene has been found to decrease the risk of developing Type 2 diabetes by 14 percent. The discovery could lead to personalized treatment and prevention strategies for millions of diabetics worldwide.
Researchers at Duke-NUS Medical School have discovered a long non-coding RNA that regulates brown fat development in mice. This finding holds promise for developing new therapeutic strategies to prevent and treat obesity.
Experts in British Journal of Sports Medicine say regular exercise is key to staving off serious disease, but calorie-laden diets generate more ill health than physical inactivity. The evidence suggests up to 40% of those within a normal weight range harbor harmful metabolic abnormalities.
A new study by the University of Sheffield identified six distinct groups of obese individuals, each requiring unique strategies for weight loss and healthy lifestyle promotion. The research suggests that targeting interventions according to an individual's 'type' could lead to more effective and efficient use of NHS services.
Research found a significant association between obesity and increased prostate cancer risk in African American men, with the risk growing nearly four times as body-mass index (BMI) increased. Obesity was also linked to a higher risk of aggressive disease and prostate cancer death among this population.
A recent study found that obesity substantially increases prostate cancer risk in African-American men, while having a moderate effect on non-Hispanic white men. The research suggests that obesity may play an important role in the 'African-American race effect' on prostate cancer disparities.
Research published in The Lancet Diabetes & Endocrinology suggests that being underweight in middle age is associated with a higher risk of developing dementia. In contrast, obese middle-aged individuals are nearly 30% less likely to develop dementia than those of a healthy weight, contradicting previous research findings.
In a pilot study, older adults aged 60+ reduced their sitting time by an average of 27 minutes per day through coaching. Participants reported improved ability to perform everyday tasks and fewer symptoms of depression. The study suggests that reducing sedentary behavior in older adults could have significant health benefits.
A University of Calgary study found that rats fed a fibre supplement while on a high fat and high sugar diet showed a much lower weight gain than those who did not eat the fibre. The study suggests that oligofructose, a naturally occurring dietary fibre, may help reduce weight gain by affecting gut microbiota and gut hormones.
A review of thousands of studies found that only a few dozen programs meet the scientific gold standard for reliability. Jenny Craig and Weight Watchers showed promise with participants losing more weight than non-participants in trials lasting 12 months or longer.
Researchers found that Weight Watchers and Jenny Craig are the most effective commercial weight-loss programs for long-term weight loss. In contrast, physical therapy was as effective as surgery in alleviating symptoms of lumber spinal stenosis. Leading internists also advocate for a more thoughtful approach to cardiopulmonary resuscit...
An observational study of San Antonio men and women aged 65+ found that frequent diet soda consumption was associated with significant increases in waist circumference over 9 years. The risk of metabolic disease, diabetes, heart attack, stroke, cancer, and mortality also rose proportionally.
Researchers discover that metformin and resveratrol activate molecules in the small intestine, triggering a neuronal network to lower blood sugar. The findings suggest targeting the gut with small compounds could represent an alternative strategy to lower glucose levels and reduce diabetic complications.
A team of researchers has found tiny genetic triggers inside brain cells that regulate appetite and weight. The discovery reveals how a protein called Islet 1 and two small stretches of DNA act as triggers for the Pomc gene, which controls feelings of fullness or hunger.
The American Cancer Society's new report highlights disparities in cancer prevention and early detection efforts, including underutilized screening for colorectal and cervical cancers. Meanwhile, tobacco use remains a major cause of preventable disease and premature death, with wide variation by education and race/ethnicity.
A study published in The FASEB Journal found that the androgen receptor confers protection against diet-induced atherosclerosis, obesity, and dyslipidemia in female mice. Researchers discovered this association by comparing female mice with and without the androgen receptor.
A study published in Diabetologia found that spending more time watching TV daily increases the risk of developing diabetes by 3.4%. The research used data from participants in the Diabetes Prevention Program, which showed a reduction in sitting behavior despite the absence of specific goals aimed at reducing it.
New research from the University of Georgia found that physician advice leads to a reported 10-pound loss for women and 12-pound loss for men over a one-year period. Tailored opinions from physicians can help identify obesity risks and promote long-term weight loss.
The study found that reality TV shows like Jersey Shore and The Real World feature idealized bodies, with two-thirds of women and three-quarters of men having little body fat. In contrast, only one in every three Americans is at a healthy weight.
Energy balance experts from six continents collaborate to develop innovative approaches to prevent and reduce obesity. The Global Energy Balance Network will convene a 'think, do tank' in 2016 to explore new solutions.
A two-year study found that workplace wellness programs can effectively reduce the number of people considered overweight or obese by almost 9 percent. Employee involvement in designing and participating in these programs was key to driving broader participation and meaningful improvements in health.
A recent analysis published in the Journal of Human Nutrition & Food Science found that dietary magnesium intake is associated with improvements in diabetes-related health outcomes. Adults who met the estimated average requirement for magnesium from food alone had significantly lower odds ratios for metabolic syndrome, obesity, and ele...
A University of Florida study found that higher levels of vitamin D may decrease pain and improve function in obese individuals with osteoarthritis. The researchers analyzed blood samples from a racially diverse group of adults and found an association between obesity and vitamin D status.
Brown fat tissue communicates with the brain through sensory nerves, possibly sharing information that is important for fighting human obesity. The study found that when brown fat tissue was activated with a drug, it talked back to the brain by activating sensory nerves.
Researchers from CNIO have developed a new anti-obesity treatment that reduces body weight and improves metabolic syndrome symptoms in obese mice and monkeys. The treatment, CNIO-PI3Ki, selectively targets the storage of nutrients in excess, leading to weight loss without affecting other tissues or brain function.
Two new studies at Hospital for Special Surgery found that bariatric surgery prior to joint replacement significantly improves outcomes in obese patients. The research shows that weight-loss surgery can reduce the risk of heart disease, diabetes, and certain cancers, while also decreasing costs and complications associated with hip or ...
A new study found that medication for type II diabetes activates sensors on brain cells, increasing hunger and leading to weight gain. Researchers at Georgia State University discovered the role of peroxisome proliferator-activated receptor Upsih (PPAR&Upsih) sensors in controlling eating behavior.
A study from the University of Eastern Finland found that risk factor levels even below accepted thresholds can be harmful when several risk factors cluster. Clustered risk factors were linked to elevated liver enzymes in overweight children, particularly those with a common PNPLA3 gene mutation.
Scientists developed a new way to cook rice that increases resistant starch content, potentially reducing calories absorbed by the body by over half. This simple cooking method can transform digestible starch into indigestible resistant starch, lowering usable calories and addressing obesity rates.
Researchers have programmed bacteria to generate a hunger-suppressing lipid, leading to reduced body fat and staved-off diabetes in mice. The therapeutic bacteria could provide sustained drug delivery, potentially improving weight loss outcomes for humans.
A new RAND Corporation study reveals that Los Angeles' fast-food ban has failed to improve diets or reduce obesity rates in low-income areas. Despite the ban, fast-food consumption increased and obesity rates rose faster than in other parts of the city.
Researchers found that visual cues associated with overweight people influence one's sense of smell, and participants with higher BMI tend to be more critical of heavier individuals. This study suggests that weight stigma may be more pervasive than previously thought, affecting everyday life in various ways.
A study of 503 Mexican-Americans found that nearly 78% were metabolically unhealthy, with a high prevalence of cardiometabolic risk factors. The research suggests that metabolic risk has a greater effect on developing atherosclerosis, regardless of obesity status.
Research suggests that too much artificial light in the evening can disrupt the body's circadian rhythm and lead to health problems such as breast cancer, obesity, diabetes, and depression. Experts recommend using devices with dimmer, longer wavelengths of light in the evening to minimize disruption.
A study published in the Journal of the American Geriatrics Society found that diet soda intake is directly linked to greater abdominal obesity in adults 65 years of age and older. Increasing waist circumference was associated with escalating cardiometabolic risk in older adults.
A study led by Massachusetts General Hospital investigators suggests that bariatric surgery can significantly reduce the risk of asthma attacks in obese patients. Significant weight reduction after surgery resulted in a half reduction in serious asthma-associated events, including emergency department visits and hospitalizations.
A new study from Brigham Young University finds that loneliness and social isolation are major risk factors for mortality across all ages and income levels. The research analyzed data from over 3 million participants and found that the lack of social connections presents an added risk, while the existence of relationships provides a po...
A review of nutrition and weight-loss interventions found a gap in approaches for people with neurological disabilities, who struggle to lose weight due to limited mobility. The study identified 27 behavior-changing techniques targeting weight-loss for people with disabilities, including self-monitoring and managing time.
A study by Deakin University found that many Australian online health information is too difficult to read, leading to potential misinterpretation and inappropriate healthcare decisions. The researchers suggest that websites need to be assessed for readability and changes made to improve accessibility.
A new study reveals that mucosal-associated invariant T (MAIT) cells are dramatically reduced in individuals with type 2 diabetes and severe obesity, yet abundant in adipose tissue. MAIT cell abnormalities may contribute to obesity-associated metabolic alterations after weight loss restored circulating MAIT cells.
A study from Thailand finds that 56% of pregnant women with diet-controlled gestational diabetes have obstructive sleep apnea. The severity of sleep disordered breathing is associated with higher blood glucose levels and greater daytime sleepiness, highlighting the importance of OSA diagnosis in this population.
A new experimental drug, GC-1, has been found to convert 'bad' white fat into 'good' brown-like fat, leading to weight loss and improved insulin sensitivity in mice. Researchers believe this conversion may help treat obesity and metabolic disease.
A recent study found that patients on liraglutide achieved at least 5% weight loss, showing improvements in health markers, blood sugar control, and blood pressure. The results suggest liraglutide as a treatment option for obesity with significant health benefits.
A new study shows that letrozole at a low dose can normalize testosterone levels and sperm production in obese men with infertility. The treatment led to successful pregnancies and births in three couples, offering a promising new hope for male infertility treatments.
A new study found that gastric bypass surgery in adolescents significantly improved bone density, which returned to normal levels within two years. The results suggest that obesity surgery may have favorable effects on the adolescent skeleton.
A new study suggests that mindfulness-based stress reduction (MBSR) can decrease fasting glucose levels and improve quality of life in overweight and obese women. MBSR significantly reduces perceived stress and improves sleep, depression, anxiety, and psychological distress without changing body weight or insulin resistance.
A study of 200 adult men with borderline testosterone levels found that 56% had significant depressive symptoms, highlighting the need for clinicians to manage comorbidities like depression and obesity in this population. The researchers also noted a high prevalence of overweight, obesity, and physical inactivity among participants.