Articles tagged with Obesity
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A Cornell study reveals that stiffer breast tissue in obese women promotes tumor growth, changing the extracellular matrix's consistency similar to tumors. This finding may require finer-scale imaging techniques in mammograms for early detection.
A large study of over 13,000 pairs of sisters found that firstborn women are significantly more likely to be overweight or obese than their second-born sisters. The researchers also noted a link between shrinking family size and an increase in adult body mass index (BMI) globally.
Researchers found altered mitochondrial DNA in pre-diabetic individuals with insulin resistance, who had lower amounts of mitochondrial DNA and higher methylation levels. This discovery may help prevent Type II diabetes by identifying a biomarker for early intervention.
Researchers at MIT and Harvard Medical School discovered a new pathway that controls human metabolism by prompting adipocytes to store or burn fat. The study identified two master controllers of thermogenesis, IRX3 and IRX5, which turn off fat storage genes and restore energy balance.
A study led by Beth Israel Deaconess Medical Center and MIT reveals a genetic circuit controlling fat storage versus burning. The research identifies two key genes, IRX3 and IRX5, which are under the control of the FTO gene variant associated with obesity. Manipulating this pathway may offer a new treatment approach for obesity.
A regular dose of aspirin reverses the long-term risk of cancer in those who are overweight, according to a study published in Journal of Clinical Oncology. The research found that being overweight more than doubles the risk of bowel cancer in people with Lynch Syndrome.
A £500,000 National Cancer Institute grant has enabled UK researcher Fredrick Onono to explore the potential connection between high-fat diets and breast cancer development. The study may uncover how fats contribute to cell malfunctions, potentially leading to treatment-resistant cases.
A recent NIH study found that restricting dietary fat led to a 68% higher rate of body fat loss compared to cutting the same number of carbohydrate calories. The researchers discovered that fat restriction resulted in a greater imbalance between consumed and burned fat, leading to more significant weight loss.
Heavy smokers and obese individuals may experience significant weight gain after quitting smoking due to factors like daily cigarette consumption and body mass index. Researchers analyzed data from over 12,000 participants to find that those who quit smoking gained an average of 23 pounds among smokers of 25 or more cigarettes per day.
A high-protein breakfast containing 35 grams of protein prevented gains of body fat and stabilized glucose levels among overweight teens who skipped breakfast. Eating a high-protein breakfast also led to reduced daily food intake and improved feelings of hunger.
A study from the University of Iowa found that portable pedaling devices under desks can inspire active work habits in sedentary employees. Participants who used these devices for 50 minutes a day over 16 weeks showed significant benefits.
The FDA has approved two new endoscopic bariatric therapies for treating obesity, providing patients with a minimally invasive alternative to surgery. Endoscopic bariatric therapies offer a viable option for patients who have been unsuccessful at weight loss with diet and exercise.
A recent study published in JAMA Surgery found that patients who underwent laparoscopic sleeve gastrectomy experienced significant weight regain and a decrease in remission rates for type 2 diabetes and other obesity-related disorders over time. The study collected data from 443 patients who underwent the procedure between 2006 and 201...
A new study found that bariatric surgeries alter the gut microbiome in ways that last for at least a decade, leading to sustained weight loss and improved metabolic health. The changes are specific to the surgery and not just a reflection of weight loss alone.
A new study published in the International Journal of Workplace Health Management suggests that Health Codes of Conduct can effectively engage employees in wellness activities. The study found that features such as annual physicals, exercise routines, and recognition programs were most supported by participants.
Reevaluating pet feeding regimens can help combat pet obesity, with customized diets tailored to individual animals' unique needs. Maintaining a lean body condition score adds years to dogs' lives, while raw and whole-prey diets may offer an alternative to extruded ones.
A randomized controlled trial found that individualized lifestyle counseling reduced gestational diabetes incidence in high-risk pregnant women. The study showed a significant reduction in GDM diagnosis and improved health outcomes for both mothers and children.
A University of Queensland study has found that drinking alcohol around the time of conception increases the risk of type 2 diabetes and obesity in early middle age. Research using laboratory rat models showed that exposure to five standard drinks before implantation causes changes to the embryo, leading to increased risk.
Experts weigh in on whether a sugar tax can help combat obesity, with some arguing it's a necessary step to reduce consumption and others claiming it would be economically ineffective. A sugar tax on all products may stimulate reformulated products, while taxes on specific food categories could change diets and improve health.
Researchers have developed micelle sequestrant polymers that capture fat particles in the intestines, preventing their absorption and excretion. This breakthrough could lead to a safe and effective anti-obesity drug with long-term benefits.
A study published in Radiology found associations between specific cardiovascular risk factors, such as alcohol consumption and smoking, and reduced brain volume in key regions. These findings suggest that risk factors may be early indicators of cognitive decline and Alzheimer's disease.
Researchers found that baby rats whose mothers were fed a high-fat diet had smaller bitter taste receptors in their hearts and larger hearts than normal, suggesting an impact on cardiovascular health.
A four-year study aims to understand the neurological mechanisms behind reduced taste for sweet and fatty foods following Roux-en-Y gastric bypass surgery and diet-induced obesity. The research seeks to identify new treatments for effective weight loss and shed light on why RYGB is an effective surgical treatment for obesity.
Scientists at the University of Southampton have developed a molecule that acts as an exercise mimic, reducing fasting blood glucose levels and promoting weight loss in obese mice. The new compound 14 inhibits a cellular enzyme involved in metabolism, leading to improved glucose tolerance and reduced body weight.
Two studies published in Gastroenterology found that weight loss through lifestyle modification or bariatric surgery significantly reduces NASH features. Lifestyle modifications resulted in a 10% weight reduction needed to reverse scarring, while bariatric surgery eliminated NASH in 85% of patients after one year.
A University of Delaware-led study found that an intensive regimen of regular exercise and a healthy diet can reduce the short-term onset of knee pain for overweight adults with Type 2 diabetes. The study, published in Arthritis Care and Research, shows a 15% decrease in knee pain development among those who underwent the intensive pro...
A recent study published in PLOS ONE found that a high-soybean-oil diet caused significant weight gain, diabetes, and insulin resistance in mice compared to diets high in coconut oil or fructose. The researchers used mice fed different diets containing various types of fats to investigate the effects on obesity and metabolic syndrome.
A new study by Cornell's Food & Brand Lab analyzed 50 years of New York Times food stories to predict a country's obesity level in three years. The study found that countries with more mentions of sweet snacks tend to be fatter, while those with more vegetable and fruit mentions are skinnier.
A new study published in Social Science & Medicine proposes taxing sugary drinks based on their calorie content to encourage healthier choices. This approach could lead to a reduction in obesity rates and an increase in the consumption of low-calorie alternatives.
A study published in the American Journal of Public Health found that obese individuals have a low chance of recovering normal body weight, with only 1 in 210 men and 1 in 124 women achieving this goal. The research highlights the need for obesity prevention strategies to address the rising obesity epidemic.
Researchers found that children on summer break consume more sugar, watch more TV, and eat fewer vegetables than the rest of the year. Despite differences in obesity behaviors between income groups, overall patterns were similar across households above and below poverty thresholds.
A new study published in the American Journal of Preventive Medicine found that increasing numbers of overweight adolescents do not consider themselves overweight. This misperception is linked to a decline in willingness to make weight-related behavioral changes, despite being at risk for obesity.
A gene mutation called ankyrin-B has been found to cause cells to absorb glucose faster, leading to fat storage and type 2 diabetes. The mutations are common among certain populations, including African Americans and Caucasians, and may provide a genetic link to modern diet-related diseases.
A study led by Harvard Medical School geneticists reveals that blind cavefish have mutations in the MC4R gene, which is also mutated in certain obese people. The findings provide insights into how vertebrates evolved different metabolisms and could inform the search for genes influencing human metabolism and obesity.
A CU-Boulder-led study found that children consume more low-nutrition, high-calorie food after seeing seemingly overweight cartoon characters. The study shows kids apply typically human standards to cartoon creatures and can influence them to eat more junk food.
Research published in Veterinary Record found that one in four UK show dogs competing at Crufts was overweight, despite breed standards emphasizing ideal condition. The study suggests that widespread online exposure of show dog images may be normalizing canine obesity.
Researchers at the University of Liverpool found that up to 26% of show dogs, particularly pugs, Basset hounds, and Labradors, are overweight due to their breeding history for physical activity. The team graded body condition and found significant health issues such as arthritis, diabetes, and respiratory diseases in obese dogs.
Research published in Cell Metabolism reveals that ancestral undernutrition can lead to obesity and metabolic disorders, increasing the risk of type 2 diabetes. A study on rats found that descendants of undernourished ancestors were eight times more likely to develop diabetes when switched to a normal diet.
A Cancer Research UK study found that almost three-quarters of overweight or obese 13-15-year-olds are in the normal-weight range. The study showed that only around 40% of these teens thought they were too heavy, while seven per cent believed they were too light.
A large-scale trial found that an intensive diet and exercise regime does not prevent gestational diabetes in obese pregnant women. However, the intervention led to reductions in pregnancy weight gain, lower glycaemic load, and higher activity levels, which were associated with healthier outcomes for mothers and children.
A new Iowa State University study found that instigation habits, or cues, are more effective than execution habits in increasing exercise frequency. The research suggests that internal cues, such as a feeling of needing to move after sitting for several hours, form the strongest habits and can be trained over time.
Reducing stillbirth risk calls for improved pregnancy monitoring and early detection of high-risk pregnancies. Targeted delivery interventions, such as induced labor and low-dose aspirin, may also help lower stillbirth rates.
Researchers say that daily intake of more than three times the recommended minimum is needed to restore a healthy blood level of vitamin D in overweight or obese blacks. Higher doses were found to be more effective at suppressing parathyroid hormone and improving bone health.
Researchers found that obese adults have a heightened ability to imagine odors, particularly food and non-food smells, which may promote food cravings. This study's findings suggest the need for individualized approaches to identify factors contributing to weight gain.
A study of 61 obese participants with type 2 diabetes mellitus found that bariatric surgery resulted in more disease remission than lifestyle intervention alone. At 3 years, 40% of those who underwent RYGB achieved complete remission, compared to 15% of those who received LAGB and no intensive lifestyle weight loss intervention.
A recent weight loss study showed significant improvements with liraglutide treatment, resulting in an average weight loss of 8.4 kg. The Temple doctors emphasized that modest weight loss can be considerable and improve medical issues, but more research is needed for longer-term results.
A study by University of Illinois professor Ruopeng An found that eating at restaurants consumes more calories, fat, and sodium than eating at home. African-Americans who dine out take in more total fat, saturated fat, sodium, and sugar.
A pooled analysis of patients with metastatic colorectal cancer (mCRC) treated with bevacizumab found that those with the lowest body mass index (BMI) had significantly shorter overall survival compared to other BMI categories. Progression-free survival was similar across all subgroups.
Patients with a low to healthy body weight had an average survival time of two-and-a-half months less than overweight and obese patients. The study suggests that there may be a relationship between having a lower BMI and poor treatment tolerance, putting thinner patients at risk for poor outcomes.
A recent study published in the Bulletin of the World Health Organization found a strong correlation between global increases in food energy supply and obesity rates. The research analyzed data from 69 countries and discovered that both body weight and food energy supply had increased in 81% of them between 1971 and 2010.
Researchers at Imperial College London have identified a new genetic defect that causes severe obesity and type 2 diabetes in humans. The defect is associated with an impaired protein called carboxypeptidase-E, which regulates appetite, insulin, and reproductive hormones.
A Johns Hopkins Bloomberg School of Public Health pilot program found that offering healthier menu items at carryout stores increased gross revenue by an average 25%, not just improved health. The study, published in the American Journal of Health Promotion, suggests that convincing more carryouts to alter their menus can be profitable.
Severely obese individuals undergoing weight-loss surgery experience substantial improvements in urinary incontinence, with a majority achieving remission three years after bariatric surgery. The more weight lost, the higher the chances of improvement, and those who were older or had severe walking limitations showed less improvement.
The study found that Akkermansia muciniphila is associated with lower fasting blood glucose and insulin levels, as well as a smaller waist:hip ratio and reduced body fat cell volume. Those with higher abundance of the microbe showed stronger improvement in their metabolic profile after calorie restriction.
A recent study found that adult Americans aged 25 and older have become increasingly obese, with 67.6 million estimated to be obese and 65.2 million considered overweight.
The study found that 39.96% of men and 29.74% of women were overweight, while 35.04% of men and 36.84% of women were obese. These rates are associated with a range of chronic health conditions.
WSU scientists demonstrate that resveratrol converts excess white fat into beige fat, reducing weight gain by 40%. Polyphenols found in fruit enhance fat oxidation, preventing obesity and metabolic dysfunction. Increasing fruit consumption can boost total polyphenolic intake.
Researchers have discovered that an existing drug, rapamycin, reduces body fat and appetite in older rats, preserving lean body mass. The study's findings have implications for developing anti-obesity treatments for aging humans, with potential benefits including improved health outcomes.
Researchers discovered that rapamycin, a pharmaceutical used to prevent transplant rejection, reduces body fat and appetite in older rats, preserving lean body mass. The drug targets how the body makes leptin, a hormone that affects hunger and metabolism.
A large-scale analysis found that postmenopausal women who were overweight and obese had a higher risk of invasive breast cancer compared to those of normal weight. The study, published in JAMA Oncology, suggests that obesity may contribute to an increased risk of breast cancer.