Articles tagged with Obesity
Elderly adults who live in homes with cooler temperatures during the winter season tend to have smaller waistlines compared to those living in warmer environments. Researchers found that safe cold exposure can be an effective preventive measure against obesity.
Researchers found that metabolically healthy obese individuals tend to be younger and more likely to engage in physical exercise. They were also less likely to smoke or drink heavily. Metabolically unhealthy individuals, on the other hand, had factors such as high cholesterol, age, and smoking status associated with their health.
The world is experiencing a shift in global body mass index (BMI) trends, with more people becoming obese than underweight. By 2025, around a fifth of adults worldwide are projected to be obese, with over 6% of men and 9% of women expected to be severely obese.
Researchers have identified 10 oft-repeated errors in obesity studies, including pre-post differences between groups, cluster randomized trials, and meta-analysis calculation errors. These flaws can lead to inaccurate weight loss results and undermine the validity of obesity research.
Researchers at Ohio State University have found that deleting microRNA-155 in female mice prevents weight gain on a high-fat diet. The study shows a 56% reduction in obesity and a 74% reduction in fat accumulation.
A new study from Newcastle University found that people who reverse their Type 2 diabetes and keep their weight down remain free of the condition. The research shows that even patients with diabetes for up to 10 years can reverse their condition by removing fat from their pancreas.
A new study by Rice University researchers found that obese women, even those with higher education, are double the risk of depression compared to normal-weight women. The study used a large population-based sample of healthy women and controlled for various factors, including diet and lifestyle.
A study published in Diabetologia found that bariatric surgery significantly improved type 2 diabetes remission rates compared to an intensive lifestyle and medical intervention. Patients with mild-to-moderate obesity experienced greater weight loss, improved glucose control, and reduced need for diabetes medications after RYGB.
Researchers identified O-GlcNAc transferase (OGT) as a key enzyme regulating food intake in mice. Deletion of OGT caused mice to overeat and become obese, suggesting a new treatment target for human obesity.
Researchers discovered a microRNA called miR-181b that controls the function of vessels in adipose tissue, improving insulin sensitivity and glucose levels. The study found that reconstituting this microRNA in obese mice reduced inflammation in adipose tissue, suggesting potential new targets for obesity and diabetes treatment.
A recent study published in JAMA Neurology found that obese women who use oral contraceptives are at a higher risk for cerebral venous thrombosis (CVT), a rare and potentially life-threatening condition. The study also suggests that alternative methods of contraception, such as intrauterine devices, may be safer options for obese women.
The study reveals that TRPV2 is essential for thermogenesis in mouse brown adipose tissue. Without TRPV2, mice exhibit impaired thermogenesis and increased obesity on high-fat diet treatment.
Researchers found that lead exposure during gestation and lactation altered the gut microbiota of adult mice, leading to increased body weight. The study suggests a potential link between early life lead exposure and obesity in adulthood.
Breast cancer is more aggressive and common in obese women due to peritumoral fat facilitating the expansion of cancer stem cells. Researchers found that interactions between tumor cells and immature adipocytes increase cytokine secretion, leading to increased CSCs and metastasis.
A Kansas State University researcher found that an integrated approach to address hot topics like substance use, obesity, and mental health is critical for teen health. The research involved a mixed-methods approach, collecting data from online surveys, community focus groups, and interviews with key individuals.
A team of scientists at the University of Bonn discovered a switch that can convert unwanted white fat cells into energy-burning brown cells by blocking Gq proteins. This breakthrough has significant implications for obesity treatment, as it may lead to the development of pharmaceutical products that target this pathway.
A new study suggests that mindful eating can improve glucose levels and heart health, even beyond weight loss. Researchers found greater improvements in cardiometabolic outcomes tied to Type 2 Diabetes and cardiovascular disease with a mindfulness-based weight-loss intervention.
A national study examining how men feel about their bodies found that between 20-40% of men reported feeling dissatisfied with their physical appearance. Gay men were more likely to report feelings of pressure from the media, social pressures, and discomfort in public, highlighting common issues across both heterosexual and gay men.
A study published in The BMJ found that shorter height in men and higher body mass index (BMI) in women are associated with lower socioeconomic status, including reduced income. The research used genetic data from 120,000 participants to analyze the link between height, weight, and socioeconomic factors.
Researchers will focus on brain-derived neurotrophic factor (BDNF) and its receptor TrkB to develop novel interventions for obesity. The study aims to understand the mechanisms governing energy balance in the body.
A study by the BMJ found that shorter height and higher BMI are associated with lower levels of education, job status, and income, particularly among men and women. The research suggests that taller stature is linked to higher social position, while being overweight or short can lead to socioeconomic disadvantages.
Researchers discovered that changes in gut bacteria are strongly associated with PCOS-related obesity and signs of diabetes. Modifying the gut microbiome may be a potential treatment option for women with PCOS.
The naltrexone-bupropion treatment combination reduced weight in phase 3 clinical trials but lacked demonstration of cardiovascular benefits. A trial with 8,910 patients was terminated early due to premature release of interim data, casting doubt on the treatment's safety profile.
A study found that a variant of the p53 tumor suppressor gene is linked to obesity and type 2 diabetes, with mice carrying the variant showing increased weight gain and glucose intolerance. The research suggests that the variant may have evolved in colder climates to promote energy storage, but its modern-day implications are negative.
Researchers from the University of Cologne have successfully inhibited a protein that hampers activation of brown fat in mice, leading to improved glucose metabolism. By feeding Bace1 inhibitors to these animals, scientists were able to activate their brown fat and alleviate metabolic problems.
Researchers at Helmholtz Munich identified a new component regulating body weight and food intake, with histone deacetylase 5 (HDAC5) playing a significant influence on leptin's effect. The study found that HDAC5 is essential for the brain to recognize fat depot levels, enabling adaptation to food intake and reducing obesity.
A study led by SUNY Downstate Health Science University found increased risk of obesity among Filipino immigrants living in the New York City metropolitan area. The findings suggest that prolonged US residency erodes the health advantage initially carried by immigrants, a process known as 'unhealthy assimilation'.
A Georgia State University biologist has received a four-year, $1.37 million grant from the National Institute of Health (NIH) to study epigenetic mechanisms and their link to obesity. The researcher aims to induce brown adipocytes in white fat tissues to prevent and treat obesity.
Researchers found an association between high BMI and poorer performance on a test of episodic memory in young adults. The study suggests that obesity may be linked to changes in brain structure and function, potentially affecting memory and decision-making abilities.
Researchers found a significant reduction in emergency department visits and hospitalizations for heart failure exacerbation after bariatric surgery. Patients who underwent the procedure experienced a 40% decrease in these events, suggesting substantial weight loss can help prevent heart-failure-related adverse events.
Researchers from Rockefeller University have identified a hormone called amylin as a critical component of the system responsible for regulating food intake. Amylin acts in the brain to help control consumption, working in concert with another hormone leptin to control body weight.
Research finds that lymphatic vessels play a critical role in obesity development, with chyle leakage triggering weight gain and insulin resistance. Restoring lymphatic function reverses obesity in Prox1-haploinsufficient mice.
Researchers found that omega-3 supplementation reduced breast density in postmenopausal women with a body mass index above 29, bordering on obesity. The study suggests that DHA alone may be preferentially protective in these individuals, offering an example of personalized approach to breast cancer prevention.
A recent study by researchers at the University of California, Davis, found that gamers using thin avatars showed increased physical activity compared to those using obese avatars. The study replicated previous findings on both male and female participants.
A new study from Michigan State University finds that fat cells, not lean cells, have a longer lifespan. The researchers used yeast to demonstrate that increasing the cellular content of triacylglycerol, or fat, extends lifespan. This finding supports the obesity paradox theory and has implications for human aging and health.
A study of 399 participants found an association between higher mindfulness scores and healthier glucose levels. The researchers identified obesity risk and sense of control as potential mediators of this link, with mindful individuals being less likely to be obese and more likely to believe they can change their lives.
A new study found that losing just 5% of body weight has significant health benefits for obese patients, including reduced risk for diabetes and cardiovascular disease. The study also showed improvements in metabolic function in liver, fat, and muscle tissue.
A randomized controlled trial found that losing just 5% of body weight significantly improves health outcomes, including insulin sensitivity and reduced risk factors for metabolic diseases. Additional weight loss further improves health benefits, but the study shows that even a small amount of weight loss has important health benefits.
Higher body weight and taller stature during adolescence may increase the risk of developing Non-Hodgkin's Lymphoma later in life. A study of 2,352,988 teens found a 25% increased risk of NHL associated with adolescent overweight and obesity.
A rat study published in the Journal of the Federation of American Societies for Experimental Biology found that exposure to Beijing's polluted air increases weight and metabolic dysfunctions. The study also showed that pregnant rats exposed to polluted air had higher levels of insulin resistance, a precursor to Type 2 diabetes.
A study finds that bariatric surgery prior to total knee replacement improves quality of life in morbidly obese patients with end-stage knee osteoarthritis. The research suggests a cost-effective option to reduce complications and costs associated with joint replacement, with a predicted cost per QALY of $13,910.
A North Carolina State University study contradicts previous research on weight loss stigma. Most participants who lost significant weight reported positive responses from others, with few fearing residual stigma.
A new study found an important relationship between proteins secreted by the heart and obesity, glucose intolerance and insulin resistance. Higher levels of cardiac natriuretic peptides and lower clearance receptor in adipose tissue suggest a potential new approach to treating metabolic disorders.
A study found that engaging in healthy lifestyle behaviors is linked to higher scores in measures of health literacy, self-efficacy, and readiness for change. Collaborating with spiritual organizations may be key to reducing healthcare disparities and improving modifiable risk factors among urban Black women.
Researchers investigate if estrogen plays a role in sex differences in hypertension among young, obese women. High levels of aldosterone, triggered by leptin in obesity, contribute to cardiovascular problems.
Researchers investigate sex differences in hypertension mechanisms and explore potential therapeutic strategies for premenopausal women. Studies suggest that obesity leads to increased aldosterone levels, contributing to cardiovascular problems.
Researchers at the University of Pennsylvania School of Medicine found that financial incentives framing were crucial to motivating participants. The loss incentive group, which risked losing $42 per month for not achieving their daily goal, saw a 45% increase in success rate compared to the control group.
Research from the University of Bath found that eating breakfast was associated with more physical activity and reduced food intake later in the day among obese individuals. The study, which compared a fasting group with a breakfasting group, built on previous research into the effects of breakfast on health.
Researchers discovered that obesity promotes pancreatic and breast cancer progression by increasing tumor-infiltrating immune cells and promoting a pro-tumor microenvironment. Blocking the VEGFR-1 pathway may prevent tumor growth and metastasis in obese patients, offering potential therapeutic targets for improving patient outcomes.
A new study finds that only 9% of weight loss programs adhere to expert medical guidelines, leaving consumers unclear about their regimen. The majority of programs lack essential components like high-intensity interventions and moderate physical activity.
Red raspberries contain essential nutrients like vitamin C and fiber, which may help reduce the risk of metabolically-based chronic diseases. The polyphenolic components in red raspberries have been shown to reduce oxidative stress and inflammation, making them a promising food for heart health and brain function.
A study published in JAMA Surgery found that gastric bypass surgery significantly reduced mortality rates in patients aged older than 35 years. The lack of mortality benefit for younger patients was attributed to a higher number of externally caused deaths, mainly among women.
The American College of Physicians recommends using either cognitive behavioral therapy or second-generation antidepressants to treat adults with major depressive disorder. Both treatments are found to be similarly effective for treating depression, and physicians should consider a discussion with the patient about treatment effects, a...
A new study published in the International Journal of Obesity suggests that 34.4 million Americans considered overweight by BMI are actually healthy, and 19.8 million who are considered obese are also healthy. The research reveals that BMI mislabels millions of individuals as unhealthy, while overlooking those with 'healthy' BMIs who a...
A new study published in the International Journal of Obesity found that close to half of Americans who are considered
Researchers aim to optimize synthetic ERRγ activators for potency and selectivity to advance treatments for various diseases. Previous studies in animal models suggest increased expression of ERRγ improves exercise capacity and mitochondrial function.
A study published in AIDS Research and Human Retroviruses found that 18% of overweight adults on ART became obese, and 22% of those with normal BMI became overweight. The study suggests a higher risk of additional health complications for HIV-infected individuals.
CNIC researchers have identified a new target for the treatment of fatty liver disease, p38 gamma and p38 delta proteins. Inhibition of these proteins with specific inhibitors has shown potential as a treatment for fatty liver disease, potentially preventing inflammation, liver damage, and diabetes linked to obesity.
A study by Chapman University researchers reveals that news articles portraying obesity in different ways influence people's attitudes towards obesity-related public policies and anti-fat prejudice. The 'fat rights' frame was found to reduce prejudice, while the 'public health crisis' and 'personal responsibility' frames exacerbated it.
A University of California, San Diego study found that weight loss programs emphasizing healthy fats lower both good and bad cholesterol. The walnut-rich diet had the most impact on cholesterol levels, decreasing low-density lipoprotein and increasing high-density lipoprotein.