Articles tagged with Obesity
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A recent UAlberta study reveals nearly half of severely obese patients require ICU admission and one in five do not survive after emergency surgery. The researchers attribute these findings to underlying health conditions, malnutrition, and impaired healing due to obesity.
A new study from the University of Copenhagen found that using the intestinal hormone GLP-1 in obesity treatment prevents bone loss and increases blood levels of bone formation markers. This has significant implications for future obesity treatment, particularly for menopausal women at risk of osteoporosis.
Researchers found that GLP-1 receptor activation decreases anticipatory food reward, reducing cravings, and increases feeling of food reward during consumption, reducing overeating. The study suggests a potential therapeutic target for substance abuse disorders, offering new insights into the mechanisms of obesity.
A team of scientists has identified an enzyme called Kit, which plays a key role in the development of obesity and metabolic disorders. In mice with functioning Kit, fed a high-fat diet, obesity and insulin resistance were prevented.
A Canadian study found weight loss reduced asthma severity by normalizing or improving airway hyperresponsiveness and quality of life in obese adults. The study supports treating comorbid obesity in individuals with asthma.
Boosting a naturally occurring molecule in the body can help protect against obesity-related diseases by reducing inflammation in fat tissues. The study found significant disease improvement, primarily affecting fat tissue, and demonstrated the potential of fundamental research to reduce inflammation.
A new study found that refraining from late-night calories helps prevent some of the decline in neurobehavioral performance during sleep restriction. Subjects who fasted performed better on reaction time and attention lapses than those who had eaten during late-night hours.
A new study from the University of Colorado Anschutz Medical Campus found that a low-cost, non-profit weight loss program offers clinically significant and long-term weight loss results. The TOPS program, which costs just $92 a year, was shown to be effective in maintaining weight loss for over seven years.
Bariatric surgery not only benefits patients' health but also strengthens their relationships with partners, according to a new study. Couples reported improved intimacy, better conflict resolution, and enhanced sexual relationships after one partner underwent weight loss surgery.
A team of researchers identified a yeast protein network that regulates fat storage in yeast, analogous to human obesity. The study suggests that yeast could serve as a valuable test organism for studying human obesity, with the removal of specific proteins resulting in increased cellular fat content.
People who earn a college degree before getting married are less likely to become obese, with a significant gap in risk compared to those who graduate after marriage. This association holds even when controlling for other factors, such as income and exercise habits.
Scientists from Scripps Research Institute aim to develop drugs targeting the IP6K1 enzyme to treat obesity and related metabolic diseases. The new grant will help identify underlying mechanisms of energy storage regulation.
A recent study by NYU researchers found that approximately one-third of Chinese Americans incorrectly perceive their body weight. The study explored the accuracy of body weight perception and its impact on obesity among 162 participants, revealing significant differences among participants in terms of gender, age, and education years.
A new study suggests that obese male mice produce higher levels of white blood cells that encourage inflammation, contributing to insulin resistance and Type 2 diabetes. In contrast, female mice exhibit a mild inflammatory response to obesity, indicating differences in immune system responses between sexes.
Research published in Gut journal found that being very overweight in teens doubles the risk of developing bowel cancer by middle age. High levels of systemic inflammation, measured by erythrocyte sedimentation rate (ESR), also increase the risk of bowel cancer in later life.
Research found a strong association between road traffic noise and increased waist size and waist:hip ratio, even after controlling for socioeconomic factors. The study also suggested that cumulative exposure to multiple sources of noise pollution may pose the greatest risk.
Obesity alters splicing patterns of genes TCF7L2 and INSR, leading to impaired insulin action. Weight loss reverses these changes, suggesting a targeted treatment approach for metabolic disorders. Alternative splicing regulates obesity-related gene expression, offering new diagnostic and therapeutic avenues.
A study published in PLOS ONE found that moderate caffeine consumption is associated with lower rates of erectile dysfunction. Men who consumed 85-170mg or 171-303mg of caffeine per day were 42% and 39% less likely to report ED, respectively, compared to those who drank zero to seven milligrams.
Research highlights a disparity in cardiovascular disease risk between black and white women, particularly among those with metabolic abnormalities. Black women with two or three metabolic issues have nearly double the cardiovascular event rate as normal-weight black women without these disorders.
A new study finds that shift workers are more likely to be overweight and experience sleep problems, increasing the risk of metabolic disorders like diabetes. Sufficient sleep may partially alleviate these adverse health effects.
Researchers at the University of Cincinnati found that leptin action is normal in obese individuals, not impaired as previously thought. The study suggests that restoring leptin action may not be effective in reducing obesity, requiring a new approach to understanding and treating the condition.
Scientists design a peptide that binds to ghrelin and Y2 receptors, reducing appetite in obese mice. The compound shows promise as an obesity treatment targeting the complex system of hormones regulating appetite.
A new NIH study reveals that people with certain physiologies lose less weight when limiting calories. Those with a 'thrifty' metabolism, characterized by decreased energy expenditure during fasting, tend to lose less weight during calorie-reduced periods.
A new study published in the American Journal of Preventive Medicine found that people who moved to more socioeconomically deprived neighborhoods gained additional weight. The study used data from over 3,000 Dallas County residents and found a significant association between moving to a higher-NDI neighborhood and increased weight gain.
Researchers found that using a shopping list was associated with improved dietary quality and lower weight among low-income participants living in food deserts. The study suggests that this simple tool can be an effective way to promote healthy eating habits and reduce health risks.
Researchers discovered IRF5 helps prevent metabolic complications by storing fat subcutaneously. In contrast to intra-abdominal fat, which leads to type 2 diabetes, this storage form reduces inflammation and promotes tissue remodelling.
Researchers found obesity and depression to be underlying causes of regular drowsiness, with low-grade chronic inflammation a primary mechanism for fatigue in obese individuals. Depressed individuals also experienced high incidence of EDS, likely due to physiologic sleep disturbances.
A recent study has identified the enzyme responsible for obesity-related hypertension, which breaks down a molecule necessary for relaxing blood vessels. The research suggests that targeting this enzyme may lead to new treatment options for obese patients with high blood pressure.
A meta-analysis found intragastric injection of botulinum toxin A effective for treating obesity, with significant weight loss in treated patients compared to placebo. Additionally, a study concluded that flexible endoscopes can be stored for up to 21 days after reprocessing without microbial colonization
Research found that patients with type 2 diabetes who are overweight but not obese live longer than those who are underweight or normal-weight. The 'obesity paradox' suggests that excess weight may be beneficial for survival in these patients, contrary to previous expectations. Meanwhile, daily low-molecular-weight heparin injections w...
A study found that obese patients undergoing common cosmetic plastic surgery procedures had higher rates of complications, hospital visits, and emergency department visits. The findings link obesity to increased healthcare costs, with average cost differences ranging from $3,900 to $7,400.
A study by Imperial College London identifies chemical markers in urine associated with body mass, providing insights into how obesity causes disease. The findings suggest that obesity has a 'metabolic signature' detectable in urine samples, pointing to processes that could be targeted to mitigate its effects.
A new study reveals a significant gender gap in bariatric surgery rates among U.S. men and women. Demographic, socioeconomic and cultural factors contribute to the disparity, with men undergoing surgeries at lower rates than women.
A study by Ohio State University found that people with low self-esteem related to their weight are more likely to have visible food in their homes, eat unhealthy foods, and experience depression. The home environment may contribute to obesity, but it's not a clear cause-and-effect relationship.
A new genetic mutation in the GLP1R gene has been found to decrease the risk of developing Type 2 diabetes by 14 percent. The discovery could lead to personalized treatment and prevention strategies for millions of diabetics worldwide.
Researchers at Duke-NUS Medical School have discovered a long non-coding RNA that regulates brown fat development in mice. This finding holds promise for developing new therapeutic strategies to prevent and treat obesity.
Experts in British Journal of Sports Medicine say regular exercise is key to staving off serious disease, but calorie-laden diets generate more ill health than physical inactivity. The evidence suggests up to 40% of those within a normal weight range harbor harmful metabolic abnormalities.
A new study by the University of Sheffield identified six distinct groups of obese individuals, each requiring unique strategies for weight loss and healthy lifestyle promotion. The research suggests that targeting interventions according to an individual's 'type' could lead to more effective and efficient use of NHS services.
Research found a significant association between obesity and increased prostate cancer risk in African American men, with the risk growing nearly four times as body-mass index (BMI) increased. Obesity was also linked to a higher risk of aggressive disease and prostate cancer death among this population.
A recent study found that obesity substantially increases prostate cancer risk in African-American men, while having a moderate effect on non-Hispanic white men. The research suggests that obesity may play an important role in the 'African-American race effect' on prostate cancer disparities.
Research published in The Lancet Diabetes & Endocrinology suggests that being underweight in middle age is associated with a higher risk of developing dementia. In contrast, obese middle-aged individuals are nearly 30% less likely to develop dementia than those of a healthy weight, contradicting previous research findings.
In a pilot study, older adults aged 60+ reduced their sitting time by an average of 27 minutes per day through coaching. Participants reported improved ability to perform everyday tasks and fewer symptoms of depression. The study suggests that reducing sedentary behavior in older adults could have significant health benefits.
A University of Calgary study found that rats fed a fibre supplement while on a high fat and high sugar diet showed a much lower weight gain than those who did not eat the fibre. The study suggests that oligofructose, a naturally occurring dietary fibre, may help reduce weight gain by affecting gut microbiota and gut hormones.
A review of thousands of studies found that only a few dozen programs meet the scientific gold standard for reliability. Jenny Craig and Weight Watchers showed promise with participants losing more weight than non-participants in trials lasting 12 months or longer.
Researchers found that Weight Watchers and Jenny Craig are the most effective commercial weight-loss programs for long-term weight loss. In contrast, physical therapy was as effective as surgery in alleviating symptoms of lumber spinal stenosis. Leading internists also advocate for a more thoughtful approach to cardiopulmonary resuscit...
An observational study of San Antonio men and women aged 65+ found that frequent diet soda consumption was associated with significant increases in waist circumference over 9 years. The risk of metabolic disease, diabetes, heart attack, stroke, cancer, and mortality also rose proportionally.
Researchers discover that metformin and resveratrol activate molecules in the small intestine, triggering a neuronal network to lower blood sugar. The findings suggest targeting the gut with small compounds could represent an alternative strategy to lower glucose levels and reduce diabetic complications.
A team of researchers has found tiny genetic triggers inside brain cells that regulate appetite and weight. The discovery reveals how a protein called Islet 1 and two small stretches of DNA act as triggers for the Pomc gene, which controls feelings of fullness or hunger.
The American Cancer Society's new report highlights disparities in cancer prevention and early detection efforts, including underutilized screening for colorectal and cervical cancers. Meanwhile, tobacco use remains a major cause of preventable disease and premature death, with wide variation by education and race/ethnicity.
A study published in The FASEB Journal found that the androgen receptor confers protection against diet-induced atherosclerosis, obesity, and dyslipidemia in female mice. Researchers discovered this association by comparing female mice with and without the androgen receptor.
A study published in Diabetologia found that spending more time watching TV daily increases the risk of developing diabetes by 3.4%. The research used data from participants in the Diabetes Prevention Program, which showed a reduction in sitting behavior despite the absence of specific goals aimed at reducing it.
New research from the University of Georgia found that physician advice leads to a reported 10-pound loss for women and 12-pound loss for men over a one-year period. Tailored opinions from physicians can help identify obesity risks and promote long-term weight loss.
The study found that reality TV shows like Jersey Shore and The Real World feature idealized bodies, with two-thirds of women and three-quarters of men having little body fat. In contrast, only one in every three Americans is at a healthy weight.
Energy balance experts from six continents collaborate to develop innovative approaches to prevent and reduce obesity. The Global Energy Balance Network will convene a 'think, do tank' in 2016 to explore new solutions.
A two-year study found that workplace wellness programs can effectively reduce the number of people considered overweight or obese by almost 9 percent. Employee involvement in designing and participating in these programs was key to driving broader participation and meaningful improvements in health.
A recent analysis published in the Journal of Human Nutrition & Food Science found that dietary magnesium intake is associated with improvements in diabetes-related health outcomes. Adults who met the estimated average requirement for magnesium from food alone had significantly lower odds ratios for metabolic syndrome, obesity, and ele...
A University of Florida study found that higher levels of vitamin D may decrease pain and improve function in obese individuals with osteoarthritis. The researchers analyzed blood samples from a racially diverse group of adults and found an association between obesity and vitamin D status.
Brown fat tissue communicates with the brain through sensory nerves, possibly sharing information that is important for fighting human obesity. The study found that when brown fat tissue was activated with a drug, it talked back to the brain by activating sensory nerves.
Researchers from CNIO have developed a new anti-obesity treatment that reduces body weight and improves metabolic syndrome symptoms in obese mice and monkeys. The treatment, CNIO-PI3Ki, selectively targets the storage of nutrients in excess, leading to weight loss without affecting other tissues or brain function.
Two new studies at Hospital for Special Surgery found that bariatric surgery prior to joint replacement significantly improves outcomes in obese patients. The research shows that weight-loss surgery can reduce the risk of heart disease, diabetes, and certain cancers, while also decreasing costs and complications associated with hip or ...