Articles tagged with Obesity
Researchers found that baby rats whose mothers were fed a high-fat diet had smaller bitter taste receptors in their hearts and larger hearts than normal, suggesting an impact on cardiovascular health.
A four-year study aims to understand the neurological mechanisms behind reduced taste for sweet and fatty foods following Roux-en-Y gastric bypass surgery and diet-induced obesity. The research seeks to identify new treatments for effective weight loss and shed light on why RYGB is an effective surgical treatment for obesity.
Scientists at the University of Southampton have developed a molecule that acts as an exercise mimic, reducing fasting blood glucose levels and promoting weight loss in obese mice. The new compound 14 inhibits a cellular enzyme involved in metabolism, leading to improved glucose tolerance and reduced body weight.
Two studies published in Gastroenterology found that weight loss through lifestyle modification or bariatric surgery significantly reduces NASH features. Lifestyle modifications resulted in a 10% weight reduction needed to reverse scarring, while bariatric surgery eliminated NASH in 85% of patients after one year.
A University of Delaware-led study found that an intensive regimen of regular exercise and a healthy diet can reduce the short-term onset of knee pain for overweight adults with Type 2 diabetes. The study, published in Arthritis Care and Research, shows a 15% decrease in knee pain development among those who underwent the intensive pro...
A recent study published in PLOS ONE found that a high-soybean-oil diet caused significant weight gain, diabetes, and insulin resistance in mice compared to diets high in coconut oil or fructose. The researchers used mice fed different diets containing various types of fats to investigate the effects on obesity and metabolic syndrome.
A new study by Cornell's Food & Brand Lab analyzed 50 years of New York Times food stories to predict a country's obesity level in three years. The study found that countries with more mentions of sweet snacks tend to be fatter, while those with more vegetable and fruit mentions are skinnier.
A new study published in Social Science & Medicine proposes taxing sugary drinks based on their calorie content to encourage healthier choices. This approach could lead to a reduction in obesity rates and an increase in the consumption of low-calorie alternatives.
A study published in the American Journal of Public Health found that obese individuals have a low chance of recovering normal body weight, with only 1 in 210 men and 1 in 124 women achieving this goal. The research highlights the need for obesity prevention strategies to address the rising obesity epidemic.
Researchers found that children on summer break consume more sugar, watch more TV, and eat fewer vegetables than the rest of the year. Despite differences in obesity behaviors between income groups, overall patterns were similar across households above and below poverty thresholds.
A new study published in the American Journal of Preventive Medicine found that increasing numbers of overweight adolescents do not consider themselves overweight. This misperception is linked to a decline in willingness to make weight-related behavioral changes, despite being at risk for obesity.
A gene mutation called ankyrin-B has been found to cause cells to absorb glucose faster, leading to fat storage and type 2 diabetes. The mutations are common among certain populations, including African Americans and Caucasians, and may provide a genetic link to modern diet-related diseases.
A study led by Harvard Medical School geneticists reveals that blind cavefish have mutations in the MC4R gene, which is also mutated in certain obese people. The findings provide insights into how vertebrates evolved different metabolisms and could inform the search for genes influencing human metabolism and obesity.
A CU-Boulder-led study found that children consume more low-nutrition, high-calorie food after seeing seemingly overweight cartoon characters. The study shows kids apply typically human standards to cartoon creatures and can influence them to eat more junk food.
Research published in Veterinary Record found that one in four UK show dogs competing at Crufts was overweight, despite breed standards emphasizing ideal condition. The study suggests that widespread online exposure of show dog images may be normalizing canine obesity.
Researchers at the University of Liverpool found that up to 26% of show dogs, particularly pugs, Basset hounds, and Labradors, are overweight due to their breeding history for physical activity. The team graded body condition and found significant health issues such as arthritis, diabetes, and respiratory diseases in obese dogs.
Research published in Cell Metabolism reveals that ancestral undernutrition can lead to obesity and metabolic disorders, increasing the risk of type 2 diabetes. A study on rats found that descendants of undernourished ancestors were eight times more likely to develop diabetes when switched to a normal diet.
A Cancer Research UK study found that almost three-quarters of overweight or obese 13-15-year-olds are in the normal-weight range. The study showed that only around 40% of these teens thought they were too heavy, while seven per cent believed they were too light.
A large-scale trial found that an intensive diet and exercise regime does not prevent gestational diabetes in obese pregnant women. However, the intervention led to reductions in pregnancy weight gain, lower glycaemic load, and higher activity levels, which were associated with healthier outcomes for mothers and children.
A new Iowa State University study found that instigation habits, or cues, are more effective than execution habits in increasing exercise frequency. The research suggests that internal cues, such as a feeling of needing to move after sitting for several hours, form the strongest habits and can be trained over time.
Reducing stillbirth risk calls for improved pregnancy monitoring and early detection of high-risk pregnancies. Targeted delivery interventions, such as induced labor and low-dose aspirin, may also help lower stillbirth rates.
Researchers say that daily intake of more than three times the recommended minimum is needed to restore a healthy blood level of vitamin D in overweight or obese blacks. Higher doses were found to be more effective at suppressing parathyroid hormone and improving bone health.
Researchers found that obese adults have a heightened ability to imagine odors, particularly food and non-food smells, which may promote food cravings. This study's findings suggest the need for individualized approaches to identify factors contributing to weight gain.
A study of 61 obese participants with type 2 diabetes mellitus found that bariatric surgery resulted in more disease remission than lifestyle intervention alone. At 3 years, 40% of those who underwent RYGB achieved complete remission, compared to 15% of those who received LAGB and no intensive lifestyle weight loss intervention.
A recent weight loss study showed significant improvements with liraglutide treatment, resulting in an average weight loss of 8.4 kg. The Temple doctors emphasized that modest weight loss can be considerable and improve medical issues, but more research is needed for longer-term results.
A study by University of Illinois professor Ruopeng An found that eating at restaurants consumes more calories, fat, and sodium than eating at home. African-Americans who dine out take in more total fat, saturated fat, sodium, and sugar.
A pooled analysis of patients with metastatic colorectal cancer (mCRC) treated with bevacizumab found that those with the lowest body mass index (BMI) had significantly shorter overall survival compared to other BMI categories. Progression-free survival was similar across all subgroups.
Patients with a low to healthy body weight had an average survival time of two-and-a-half months less than overweight and obese patients. The study suggests that there may be a relationship between having a lower BMI and poor treatment tolerance, putting thinner patients at risk for poor outcomes.
A recent study published in the Bulletin of the World Health Organization found a strong correlation between global increases in food energy supply and obesity rates. The research analyzed data from 69 countries and discovered that both body weight and food energy supply had increased in 81% of them between 1971 and 2010.
Researchers at Imperial College London have identified a new genetic defect that causes severe obesity and type 2 diabetes in humans. The defect is associated with an impaired protein called carboxypeptidase-E, which regulates appetite, insulin, and reproductive hormones.
A Johns Hopkins Bloomberg School of Public Health pilot program found that offering healthier menu items at carryout stores increased gross revenue by an average 25%, not just improved health. The study, published in the American Journal of Health Promotion, suggests that convincing more carryouts to alter their menus can be profitable.
Severely obese individuals undergoing weight-loss surgery experience substantial improvements in urinary incontinence, with a majority achieving remission three years after bariatric surgery. The more weight lost, the higher the chances of improvement, and those who were older or had severe walking limitations showed less improvement.
The study found that Akkermansia muciniphila is associated with lower fasting blood glucose and insulin levels, as well as a smaller waist:hip ratio and reduced body fat cell volume. Those with higher abundance of the microbe showed stronger improvement in their metabolic profile after calorie restriction.
A recent study found that adult Americans aged 25 and older have become increasingly obese, with 67.6 million estimated to be obese and 65.2 million considered overweight.
The study found that 39.96% of men and 29.74% of women were overweight, while 35.04% of men and 36.84% of women were obese. These rates are associated with a range of chronic health conditions.
WSU scientists demonstrate that resveratrol converts excess white fat into beige fat, reducing weight gain by 40%. Polyphenols found in fruit enhance fat oxidation, preventing obesity and metabolic dysfunction. Increasing fruit consumption can boost total polyphenolic intake.
Researchers have discovered that an existing drug, rapamycin, reduces body fat and appetite in older rats, preserving lean body mass. The study's findings have implications for developing anti-obesity treatments for aging humans, with potential benefits including improved health outcomes.
Researchers discovered that rapamycin, a pharmaceutical used to prevent transplant rejection, reduces body fat and appetite in older rats, preserving lean body mass. The drug targets how the body makes leptin, a hormone that affects hunger and metabolism.
A large-scale analysis found that postmenopausal women who were overweight and obese had a higher risk of invasive breast cancer compared to those of normal weight. The study, published in JAMA Oncology, suggests that obesity may contribute to an increased risk of breast cancer.
A recent UAlberta study reveals nearly half of severely obese patients require ICU admission and one in five do not survive after emergency surgery. The researchers attribute these findings to underlying health conditions, malnutrition, and impaired healing due to obesity.
A new study from the University of Copenhagen found that using the intestinal hormone GLP-1 in obesity treatment prevents bone loss and increases blood levels of bone formation markers. This has significant implications for future obesity treatment, particularly for menopausal women at risk of osteoporosis.
Researchers found that GLP-1 receptor activation decreases anticipatory food reward, reducing cravings, and increases feeling of food reward during consumption, reducing overeating. The study suggests a potential therapeutic target for substance abuse disorders, offering new insights into the mechanisms of obesity.
A team of scientists has identified an enzyme called Kit, which plays a key role in the development of obesity and metabolic disorders. In mice with functioning Kit, fed a high-fat diet, obesity and insulin resistance were prevented.
A Canadian study found weight loss reduced asthma severity by normalizing or improving airway hyperresponsiveness and quality of life in obese adults. The study supports treating comorbid obesity in individuals with asthma.
Boosting a naturally occurring molecule in the body can help protect against obesity-related diseases by reducing inflammation in fat tissues. The study found significant disease improvement, primarily affecting fat tissue, and demonstrated the potential of fundamental research to reduce inflammation.
A new study found that refraining from late-night calories helps prevent some of the decline in neurobehavioral performance during sleep restriction. Subjects who fasted performed better on reaction time and attention lapses than those who had eaten during late-night hours.
A new study from the University of Colorado Anschutz Medical Campus found that a low-cost, non-profit weight loss program offers clinically significant and long-term weight loss results. The TOPS program, which costs just $92 a year, was shown to be effective in maintaining weight loss for over seven years.
Bariatric surgery not only benefits patients' health but also strengthens their relationships with partners, according to a new study. Couples reported improved intimacy, better conflict resolution, and enhanced sexual relationships after one partner underwent weight loss surgery.
A team of researchers identified a yeast protein network that regulates fat storage in yeast, analogous to human obesity. The study suggests that yeast could serve as a valuable test organism for studying human obesity, with the removal of specific proteins resulting in increased cellular fat content.
People who earn a college degree before getting married are less likely to become obese, with a significant gap in risk compared to those who graduate after marriage. This association holds even when controlling for other factors, such as income and exercise habits.
Scientists from Scripps Research Institute aim to develop drugs targeting the IP6K1 enzyme to treat obesity and related metabolic diseases. The new grant will help identify underlying mechanisms of energy storage regulation.
A recent study by NYU researchers found that approximately one-third of Chinese Americans incorrectly perceive their body weight. The study explored the accuracy of body weight perception and its impact on obesity among 162 participants, revealing significant differences among participants in terms of gender, age, and education years.
A new study suggests that obese male mice produce higher levels of white blood cells that encourage inflammation, contributing to insulin resistance and Type 2 diabetes. In contrast, female mice exhibit a mild inflammatory response to obesity, indicating differences in immune system responses between sexes.
Research published in Gut journal found that being very overweight in teens doubles the risk of developing bowel cancer by middle age. High levels of systemic inflammation, measured by erythrocyte sedimentation rate (ESR), also increase the risk of bowel cancer in later life.
Research found a strong association between road traffic noise and increased waist size and waist:hip ratio, even after controlling for socioeconomic factors. The study also suggested that cumulative exposure to multiple sources of noise pollution may pose the greatest risk.
Obesity alters splicing patterns of genes TCF7L2 and INSR, leading to impaired insulin action. Weight loss reverses these changes, suggesting a targeted treatment approach for metabolic disorders. Alternative splicing regulates obesity-related gene expression, offering new diagnostic and therapeutic avenues.
A study published in PLOS ONE found that moderate caffeine consumption is associated with lower rates of erectile dysfunction. Men who consumed 85-170mg or 171-303mg of caffeine per day were 42% and 39% less likely to report ED, respectively, compared to those who drank zero to seven milligrams.
Research highlights a disparity in cardiovascular disease risk between black and white women, particularly among those with metabolic abnormalities. Black women with two or three metabolic issues have nearly double the cardiovascular event rate as normal-weight black women without these disorders.
A new study finds that shift workers are more likely to be overweight and experience sleep problems, increasing the risk of metabolic disorders like diabetes. Sufficient sleep may partially alleviate these adverse health effects.
Researchers at the University of Cincinnati found that leptin action is normal in obese individuals, not impaired as previously thought. The study suggests that restoring leptin action may not be effective in reducing obesity, requiring a new approach to understanding and treating the condition.