Articles tagged with Obesity
A new study suggests that mindful eating can improve glucose levels and heart health, even beyond weight loss. Researchers found greater improvements in cardiometabolic outcomes tied to Type 2 Diabetes and cardiovascular disease with a mindfulness-based weight-loss intervention.
A national study examining how men feel about their bodies found that between 20-40% of men reported feeling dissatisfied with their physical appearance. Gay men were more likely to report feelings of pressure from the media, social pressures, and discomfort in public, highlighting common issues across both heterosexual and gay men.
A study published in The BMJ found that shorter height in men and higher body mass index (BMI) in women are associated with lower socioeconomic status, including reduced income. The research used genetic data from 120,000 participants to analyze the link between height, weight, and socioeconomic factors.
Researchers will focus on brain-derived neurotrophic factor (BDNF) and its receptor TrkB to develop novel interventions for obesity. The study aims to understand the mechanisms governing energy balance in the body.
A study by the BMJ found that shorter height and higher BMI are associated with lower levels of education, job status, and income, particularly among men and women. The research suggests that taller stature is linked to higher social position, while being overweight or short can lead to socioeconomic disadvantages.
Researchers discovered that changes in gut bacteria are strongly associated with PCOS-related obesity and signs of diabetes. Modifying the gut microbiome may be a potential treatment option for women with PCOS.
The naltrexone-bupropion treatment combination reduced weight in phase 3 clinical trials but lacked demonstration of cardiovascular benefits. A trial with 8,910 patients was terminated early due to premature release of interim data, casting doubt on the treatment's safety profile.
A study found that a variant of the p53 tumor suppressor gene is linked to obesity and type 2 diabetes, with mice carrying the variant showing increased weight gain and glucose intolerance. The research suggests that the variant may have evolved in colder climates to promote energy storage, but its modern-day implications are negative.
Researchers from the University of Cologne have successfully inhibited a protein that hampers activation of brown fat in mice, leading to improved glucose metabolism. By feeding Bace1 inhibitors to these animals, scientists were able to activate their brown fat and alleviate metabolic problems.
Researchers at Helmholtz Munich identified a new component regulating body weight and food intake, with histone deacetylase 5 (HDAC5) playing a significant influence on leptin's effect. The study found that HDAC5 is essential for the brain to recognize fat depot levels, enabling adaptation to food intake and reducing obesity.
A study led by SUNY Downstate Health Science University found increased risk of obesity among Filipino immigrants living in the New York City metropolitan area. The findings suggest that prolonged US residency erodes the health advantage initially carried by immigrants, a process known as 'unhealthy assimilation'.
A Georgia State University biologist has received a four-year, $1.37 million grant from the National Institute of Health (NIH) to study epigenetic mechanisms and their link to obesity. The researcher aims to induce brown adipocytes in white fat tissues to prevent and treat obesity.
Researchers found an association between high BMI and poorer performance on a test of episodic memory in young adults. The study suggests that obesity may be linked to changes in brain structure and function, potentially affecting memory and decision-making abilities.
Researchers found a significant reduction in emergency department visits and hospitalizations for heart failure exacerbation after bariatric surgery. Patients who underwent the procedure experienced a 40% decrease in these events, suggesting substantial weight loss can help prevent heart-failure-related adverse events.
Researchers from Rockefeller University have identified a hormone called amylin as a critical component of the system responsible for regulating food intake. Amylin acts in the brain to help control consumption, working in concert with another hormone leptin to control body weight.
Research finds that lymphatic vessels play a critical role in obesity development, with chyle leakage triggering weight gain and insulin resistance. Restoring lymphatic function reverses obesity in Prox1-haploinsufficient mice.
Researchers found that omega-3 supplementation reduced breast density in postmenopausal women with a body mass index above 29, bordering on obesity. The study suggests that DHA alone may be preferentially protective in these individuals, offering an example of personalized approach to breast cancer prevention.
A recent study by researchers at the University of California, Davis, found that gamers using thin avatars showed increased physical activity compared to those using obese avatars. The study replicated previous findings on both male and female participants.
A new study from Michigan State University finds that fat cells, not lean cells, have a longer lifespan. The researchers used yeast to demonstrate that increasing the cellular content of triacylglycerol, or fat, extends lifespan. This finding supports the obesity paradox theory and has implications for human aging and health.
A study of 399 participants found an association between higher mindfulness scores and healthier glucose levels. The researchers identified obesity risk and sense of control as potential mediators of this link, with mindful individuals being less likely to be obese and more likely to believe they can change their lives.
A new study found that losing just 5% of body weight has significant health benefits for obese patients, including reduced risk for diabetes and cardiovascular disease. The study also showed improvements in metabolic function in liver, fat, and muscle tissue.
A randomized controlled trial found that losing just 5% of body weight significantly improves health outcomes, including insulin sensitivity and reduced risk factors for metabolic diseases. Additional weight loss further improves health benefits, but the study shows that even a small amount of weight loss has important health benefits.
Higher body weight and taller stature during adolescence may increase the risk of developing Non-Hodgkin's Lymphoma later in life. A study of 2,352,988 teens found a 25% increased risk of NHL associated with adolescent overweight and obesity.
A rat study published in the Journal of the Federation of American Societies for Experimental Biology found that exposure to Beijing's polluted air increases weight and metabolic dysfunctions. The study also showed that pregnant rats exposed to polluted air had higher levels of insulin resistance, a precursor to Type 2 diabetes.
A study finds that bariatric surgery prior to total knee replacement improves quality of life in morbidly obese patients with end-stage knee osteoarthritis. The research suggests a cost-effective option to reduce complications and costs associated with joint replacement, with a predicted cost per QALY of $13,910.
A North Carolina State University study contradicts previous research on weight loss stigma. Most participants who lost significant weight reported positive responses from others, with few fearing residual stigma.
A new study found an important relationship between proteins secreted by the heart and obesity, glucose intolerance and insulin resistance. Higher levels of cardiac natriuretic peptides and lower clearance receptor in adipose tissue suggest a potential new approach to treating metabolic disorders.
A study found that engaging in healthy lifestyle behaviors is linked to higher scores in measures of health literacy, self-efficacy, and readiness for change. Collaborating with spiritual organizations may be key to reducing healthcare disparities and improving modifiable risk factors among urban Black women.
Researchers investigate if estrogen plays a role in sex differences in hypertension among young, obese women. High levels of aldosterone, triggered by leptin in obesity, contribute to cardiovascular problems.
Researchers investigate sex differences in hypertension mechanisms and explore potential therapeutic strategies for premenopausal women. Studies suggest that obesity leads to increased aldosterone levels, contributing to cardiovascular problems.
Researchers at the University of Pennsylvania School of Medicine found that financial incentives framing were crucial to motivating participants. The loss incentive group, which risked losing $42 per month for not achieving their daily goal, saw a 45% increase in success rate compared to the control group.
Research from the University of Bath found that eating breakfast was associated with more physical activity and reduced food intake later in the day among obese individuals. The study, which compared a fasting group with a breakfasting group, built on previous research into the effects of breakfast on health.
Researchers discovered that obesity promotes pancreatic and breast cancer progression by increasing tumor-infiltrating immune cells and promoting a pro-tumor microenvironment. Blocking the VEGFR-1 pathway may prevent tumor growth and metastasis in obese patients, offering potential therapeutic targets for improving patient outcomes.
A new study finds that only 9% of weight loss programs adhere to expert medical guidelines, leaving consumers unclear about their regimen. The majority of programs lack essential components like high-intensity interventions and moderate physical activity.
Red raspberries contain essential nutrients like vitamin C and fiber, which may help reduce the risk of metabolically-based chronic diseases. The polyphenolic components in red raspberries have been shown to reduce oxidative stress and inflammation, making them a promising food for heart health and brain function.
A study published in JAMA Surgery found that gastric bypass surgery significantly reduced mortality rates in patients aged older than 35 years. The lack of mortality benefit for younger patients was attributed to a higher number of externally caused deaths, mainly among women.
The American College of Physicians recommends using either cognitive behavioral therapy or second-generation antidepressants to treat adults with major depressive disorder. Both treatments are found to be similarly effective for treating depression, and physicians should consider a discussion with the patient about treatment effects, a...
A new study published in the International Journal of Obesity suggests that 34.4 million Americans considered overweight by BMI are actually healthy, and 19.8 million who are considered obese are also healthy. The research reveals that BMI mislabels millions of individuals as unhealthy, while overlooking those with 'healthy' BMIs who a...
A new study published in the International Journal of Obesity found that close to half of Americans who are considered
Researchers aim to optimize synthetic ERRγ activators for potency and selectivity to advance treatments for various diseases. Previous studies in animal models suggest increased expression of ERRγ improves exercise capacity and mitochondrial function.
A study published in AIDS Research and Human Retroviruses found that 18% of overweight adults on ART became obese, and 22% of those with normal BMI became overweight. The study suggests a higher risk of additional health complications for HIV-infected individuals.
CNIC researchers have identified a new target for the treatment of fatty liver disease, p38 gamma and p38 delta proteins. Inhibition of these proteins with specific inhibitors has shown potential as a treatment for fatty liver disease, potentially preventing inflammation, liver damage, and diabetes linked to obesity.
A study by Chapman University researchers reveals that news articles portraying obesity in different ways influence people's attitudes towards obesity-related public policies and anti-fat prejudice. The 'fat rights' frame was found to reduce prejudice, while the 'public health crisis' and 'personal responsibility' frames exacerbated it.
A University of California, San Diego study found that weight loss programs emphasizing healthy fats lower both good and bad cholesterol. The walnut-rich diet had the most impact on cholesterol levels, decreasing low-density lipoprotein and increasing high-density lipoprotein.
A large study of over 6,000 Latin American women found that sedentary lifestyles are associated with severe menopause symptoms, depression, anxiety, insomnia, and obesity. Regular physical activity reduces the risk of various health problems, including breast and colon cancer, dementia, and heart disease.
A new study found that women who began their menstrual cycles at a younger age are at greater risk of developing gestational diabetes, with those starting at age 11 having a 39% higher risk. Early menarche may also be associated with obesity and hormone imbalances in adulthood.
A new study published in Radiology found that fatty liver disease is independently associated with subclinical heart failure in obese people. The study, which measured hepatic triglyceride content and cardiac function in 714 adults, suggests that dietary interventions may be crucial in preventing or reducing the risk of heart failure.
A new study supports bariatric surgery in morbidly obese patients with end-stage osteoarthritis prior to total knee replacement (TKR) surgery. The evaluation predicts improved quality-of-life and cost-effectiveness for these patients, making it a viable treatment strategy.
Endoscopic sleeve gastroplasty is a minimally invasive procedure that reduces stomach size and alters physiology, resulting in significant weight loss. The study found a 54% reduction in excess body weight at one year, with improved patient satisfaction and delayed solid food emptying.
A study of over 6 million newborns found that pre-pregnancy obesity is strongly associated with increased infant mortality rates, particularly from preterm-related causes and congenital anomalies. The risk of infant death was 32% higher for obese mothers, even after controlling for demographic factors.
Researchers found that saturated fat, but not unsaturated fat, raises sphingosine-1-phosphate levels in obese people, leading to inflammation and non-alcoholic steatohepatitis. This discovery may lead to new treatments to prevent liver disease in obese patients.
A study published in Molecular Nutrition and Food Research found that rats who cycled between healthy and junk food diets over 16 weeks showed similar gut microbiota changes to those fed junk food continuously. The researchers suggest targeting certain gut bacteria may help treat metabolic disorders.
A Swedish study of 1.5 million military conscripts found that high body mass index (BMI) and low aerobic capacity in late adolescence were associated with an increased risk of hypertension in adulthood. The combination of high BMI and low aerobic capacity was linked to a higher risk of hypertension, even among those with normal BMI.
A study published in JAMA Pediatrics found that NYC's 'water jet' machines, which provide chilled and oxygenated water, were associated with lower student weights and reduced half-pint milk purchases. The intervention increased access to drinking water in school cafeterias and was linked to a 0.025 reduction in standardized BMI.
A study published in PLOS ONE found that phthalates, commonly used in plastics, can lead to weight gain by disrupting hormone balance and metabolism. The researchers discovered that the phthalate DEHP causes an increase in unsaturated fatty acids and disrupts glucose metabolism, paving the way for weight gain.
Research at Thomas Jefferson University reveals obesity is associated with a key hormone's absence, leading to tumor suppressor pathway deactivation and increased colorectal cancer risk. A therapeutic approach using the pill linaclotide, structurally related to the lost hormone, may prevent cancer in obese patients.
Researchers found that metformin decreases inflammation and fibrosis in pancreatic cancer, which may be most prevalent in overweight and obese patients. The study also identified a potential biomarker for response to metformin treatment based on patient body weight.
A Finnish study found that high body adiposity and low physical activity are related to poorer physical fitness in children. However, physically active overweight children performed better in fitness tests compared to inactive peers.
A recent study found that smaller plates can lead to a 30% reduction in food consumption on average, particularly when diners are self-serving their portions. The research also discovered that consumers who are unaware they are being monitored are more likely to benefit from the use of smaller plates.
Adults with severe obesity who spend more time sitting are at higher risk of cardiovascular and metabolic diseases. Replacing sedentary behavior with low-intensity physical activities may improve cardiometabolic health.