Articles tagged with Obesity
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Researchers found simultaneous changes in response to obesity in almost all tissues studied, including the digestive system and internal organs. The study highlights the burden of overweight and obesity on these systems and may lead to personalized care.
A Loyola Medicine study found that robotic-assisted surgery to remove the prostate reduces the risk of blood loss and prolonged hospital stays in obese prostate cancer patients. Compared to open surgery, robotic-assisted surgery was associated with a 83% lower rate of blood transfusions and a 72% lower rate of prolonged hospital stays.
Fatty liver and visceral obesity are key predictors of prediabetes and cardiovascular risk. Insulin secretion failure and resistance also play a significant role in modulating disease risk.
A new Kaiser Permanente study found that overweight colorectal cancer patients had a significantly lower risk of death from their cancer compared to normal-weight patients. The study analyzed data from over 3,400 patients and found that those who were in the high-overweight category at diagnosis had a 55% lower risk of mortality.
A study in mice lacking the proinflammatory signaling molecule TAK1 demonstrates protection against diet-induced obesity and insulin resistance. The removal of TAK1 from mice fed a high fat diet prevented additional weight gain and improved glucose tolerance.
The article discusses patient and hernia-related factors that contribute to the success of laparoscopic ventral hernia repair. Relevant factors include obesity, smoking, diabetes, and cardiopulmonary disease, as well as hernia size, location, and recurrence.
A Drexel University study found that upgrading local corner stores with healthier stock and training did not lead to significant changes in healthy eating behaviors. Despite increased perception of food accessibility, residents' purchasing and consumption habits remained unchanged.
Researchers from the University of Missouri confirm exercise plays a crucial role in fighting obesity, with significant benefits for fat tissue and metabolism. The study found exercising rats developed different gut microbes than sedentary groups, despite eating the same amount of food, indicating exercise's importance in overall health.
Researchers found that obese women and those with anorexia nervosa struggle to distinguish between flavors, which could impact food intake. The study suggests that altering the taste intensity of food may be a potential treatment for eating disorders.
The study concludes that regular physical activity is crucial in combating the worldwide epidemic of obesity and cardiovascular disease. It confers numerous benefits, including reduced risk of coronary heart disease, type 2 diabetes, and certain cancers.
Research found a significant increase in first-time stroke hospitalizations among young Danish adults between 1994 and 2012. The study suggests lifestyle-related risk factors, such as diabetes and obesity, may contribute to this trend.
Researchers discovered a combination of compounds found in red grapes and oranges that improves glycemic control, vascular function and reduces inflammation in overweight and obese subjects. The treatment has shown promising results in a clinical trial and could lead to new treatments for diabetes and cardiovascular disease.
The NHS should significantly increase weight loss surgery rates to help patients reduce weight and obesity-related conditions. Studies show surgery is clinically effective and cost-effective, with benefits including reduced healthcare costs in the long term.
Research from the University of Cambridge found that neighborhoods saturated with fast food outlets exacerbate social inequalities in diet and obesity. Individuals with lower education levels consumed more unhealthy takeaway food and were more likely to be obese in areas with higher takeaway outlet densities.
A UK study published in Nature reveals neurotensin as a potential biological marker for the development of obesity. Neurotensin, produced mainly in the gastrointestinal tract and central nervous system, is released with fat ingestion and stimulates fatty acid absorption in the intestine.
Research reveals a decrease in excess mortality risk associated with obesity since the 1970s, with normal weight individuals now facing higher mortality rates. The study's findings suggest revising overweight categories based on updated data.
A study published in JAMA found that the BMI value associated with lowest all-cause mortality has increased by 3.3 points over three decades, from 1976-1978 to 2003-2013. The risk for all-cause mortality decreased among obese individuals, with an optimal BMI of 27 or greater found in recent cohorts.
A new study of 'The Biggest Loser' contestants found that resting metabolic rate remained suppressed even after significant weight regain. The average rate was approximately 500 calories per day lower than expected based on body composition and age.
A large study published in The BMJ found that people with a heavy body shape from childhood to middle age have the highest mortality rate. Those who remained lean throughout life had the lowest mortality risk, with a 15-year risk of death being 11.8% in women and 20.3% in men.
A genetic variant in Labradors has been identified as a key factor in their obesity-prone nature. The POMC gene affects how the brain recognizes hunger and feelings of fullness after meals.
A study found that Labrador retrievers with a genetic variation in the POMC gene are more likely to be obese and food-motivated. The deletion affects dogs' ability to produce neuropeptides, leading to increased hunger and food begging behavior.
Researchers found that young adults taught to weigh themselves daily and make small changes in diet and exercise had significantly reduced average weight gain over three years. The large change strategy led to even more effective weight loss results.
A randomized clinical trial found that 25% calorie restriction over two years improved mood, reduced tension, and enhanced general health and sexual drive in healthy adults. The study suggests that calorie restriction may provide some benefits for nonobese individuals, contradicting previous concerns about potential negative effects.
A McMaster University research team is examining how environmental factors, such as agricultural practices and toxicants, affect brown adipose tissue activity in individuals with obesity or type-2 diabetes. The studies aim to develop new strategies to enhance BAT activity for treating and preventing these diseases.
Researchers have developed nanoparticles that deliver antiobesity drugs directly to fat tissue, transforming white adipose tissue into brown and stimulating angiogenesis. The treatment resulted in a 10% weight loss in mice without adverse side effects.
A study in Mexico reveals that noncommunicable diseases, such as type 2 diabetes and hypertension, are a growing threat to maternal survival. The reclassification of 1214 deaths identified 13% more maternal deaths than previously thought, with indirect causes accounting for 12.2 deaths per 100,000 live births.
A study of 33,588 Danish twins found psoriasis associated with type 2 diabetes and obesity, with a possible common genetic cause. The prevalence of psoriasis was higher among individuals with obesity, suggesting a potential link between the two conditions.
A faith-based health promotion program, Abuelas en Acción, successfully motivated older Latinas to adopt healthier lifestyles by integrating spiritual and family values. Participants showed significant improvements in physical activity, nutrition, and stress management.
A study published in Nature Communications found that visceral fat is strongly linked to metabolic disease and insulin resistance. Researchers identified the regulatory molecule TRIP-Br2 as a key player in this process, which could lead to potential therapeutic agents against obesity.
A pilot study examining southwest tribal elders found moderate vascular risk despite hypertension treatment, highlighting the need for culturally fair instruments and biomarkers. Cognitive and depressive symptoms were also significant factors in the research results.
Researchers found that benzyl butyl phthalate (BBP) causes larger lipid droplet accumulation in cells, potentially leading to obesity. The study's results suggest a possible link between BBP exposure and adipogenesis, a process contributing to fat cell development.
A 2-year study found that bupropion (Wellbutrin) is the only antidepressant to induce modest weight loss, while others lead to varying degrees of weight gain. Nonsmokers on bupropion lost an average of 2.4 pounds, compared to a 4.6-pound gain on fluoxetine.
A new study demonstrates that a build-up of fat around the waist can cause more serious complications than obesity in the development of non-alcoholic fatty liver disease (NAFLD). Non-obese patients with a large waist circumference are at risk of NAFLD complications, according to the research. The study highlights the need for addition...
Scientists have discovered a potential method for battling obesity by stimulating brown fat in genetically predisposed mice, which may help treat metabolic syndrome and its related health issues. The study found that increasing heat production in the fatty tissue improved weight management and glucose control.
Research published in Diabetologia found that people with diabetes face reduced overall life expectancy and higher numbers of years living with disability compared to those without diabetes. The study estimated a loss of 3-9 years of life expectancy and 8-9 years of disability-free life expectancy for men and women with diabetes.
A recent study published in eNeuro found that overweight individuals are more prone to choosing unhealthy foods when presented with real options, unlike their lean counterparts. The researchers also discovered an association between impulsivity and consumption of unhealthy foods in overweight participants.
A study published by the University of Texas M.D. Anderson Cancer Center found a link between obesity and kidney cancer recurrence, with leptin receptors playing a key role in tumor formation. The research suggests that obesity may also impact prognosis for patients with renal cell carcinoma.
A Finnish group found that vascular endothelial growth factor B (VEGFB) can increase the density of adipose tissue vasculature, reducing inflammation and improving insulin function. Blocking the VEGFR1 receptor enhances the treatment effect by stimulating catabolic processes in adipose tissue.
A study found that a gene variation linked to obesity also affects food intake regulation by altering the expression of nearby genes. Reduced expression of these genes led to increased food intake and weight gain in mice.
Research published in The FASEB Journal suggests that maternal obesity and poor nutrition during pregnancy can impair the fertility of female offspring. The study found that daughters whose mothers ate a high-fat, high-sugar diet had fewer eggs than normal.
A multi-site clinical trial is assessing the safety and effectiveness of bariatric arterial embolization in treating patients with morbid obesity. The procedure targets ghrelin, reducing hunger sensation and promoting weight loss.
New research reveals dramatic worldwide increases in body-mass index (BMI) and type 2 diabetes, with American Samoa and independent Samoa exhibiting exceptionally high prevalence of both conditions. The studies attribute the rise to factors such as globalization, changing food habits and lifestyles.
The Royal Society of Public Health advocates for introducing activity equivalent calorie labelling on food packaging to prompt people to be more mindful of their energy consumption and encourage physical activity. Public polling shows that almost half of people find current front-of-pack information confusing, but 53% would positively ...
A world-first study by QUT finds that drugs used to treat nicotine addiction can also reduce sugar cravings and consumption. The study highlights the importance of reevaluating our relationship with sweetened food, and may represent a novel new treatment strategy for obesity.
A study of 2,221 adults with severe obesity who underwent bariatric surgery found that approximately 50-70% experienced clinically significant improvements in pain and physical function over 3 years. Younger age, male sex, and weight loss were associated with greater improvements.
A high-quality protein diet, including lean beef, can improve balance, lower-body strength and walking speed in obese older adults with limited ability to exercise. This study supports the benefits of protein-enhanced meals for fostering improvements in physical function during periods of weight loss.
A pilot study found that mindfulness-based eating awareness training encouraged adolescents to eat healthier and exercise more. While the intervention had some limitations, it showed promise in reducing weight gain risk and improving physical activity levels.
A three-year study found that liraglutide can help nondiabetic overweight and obese adults lose weight and reduce their risk of developing Type 2 diabetes. After three years, 66% of participants taking liraglutide no longer had prediabetes.
In a clinical trial of 100 obese men, researchers found that adding testosterone treatment to calorie restriction resulted in increased fat loss and preserved muscle mass. The study suggests that testosterone treatment may be a useful adjunct to weight loss in obese men with low testosterone levels.
A safe, minimally invasive treatment called bariatric arterial embolization (BAE) has been shown to lead to sustained weight loss in severely obese people. BAE targets the stomach's hunger hormone production, reducing appetite and resulting in significant weight loss.
A new minimally invasive weight loss treatment called bariatric arterial embolization has shown safety and efficacy in a clinical trial, initiating weight loss and reducing hunger levels. The procedure targets the production of ghrelin, a hormone controlling hunger, with promising results in sustaining weight loss.
A new study from Intermountain Medical Center and Johns Hopkins Hospital found that abdominal obesity, or having an apple-shaped body, is a strong predictor of serious heart disease in diabetic patients. Waist circumference was also shown to be a stronger predictor of left ventricular dysfunction than total body weight or BMI.
A Paleolithic-type diet improved insulin sensitivity, reduced abdominal adiposity and body weight in obese postmenopausal women. The diet high in polyunsaturated fatty acids may have long-term beneficial effects on obesity-related disorders.
A study found that oxytocin nasal spray decreases impulsive behavior in overweight men, allowing for better self-control and reduced food intake. The treatment showed promising results with minimal side effects, suggesting a potential new approach to treating obesity.
Steroid medications like prednisolone suppress brown fat's activity, leading to weight gain and obesity. Researchers found that steroid use increases energy storage from food instead of burning it through brown fat.
Research from Australia suggests that women with PCOS report a higher prevalence of asthma, which is also linked to excess weight. The study found that PCOS status and body mass index were independently associated with asthma.
A new study suggests that liraglutide, a diabetes drug, reduces the brain's reward response to high-fat foods, making them less desirable. This effect may be beneficial for individuals with Type 2 diabetes who tend to overindulge in fatty foods as a coping mechanism.
Whey protein diet participants lost the most weight and experienced reduced hunger and glucose spikes compared to other diets. The study found that a high-protein breakfast containing whey protein induced greater satiety and reduction of glucose spikes after meals.
A new study found that combining a temporary intestinal bypass device with the drug liraglutide improves diabetes control and weight loss in patients. The combination treatment resulted in significant weight loss (12.8 kg) and improved glycated hemoglobin levels compared to other treatments.
A new meta-analysis reveals a clear correlation between higher BMI, waist circumference, and the risk of heart failure. Overweight individuals had a 35% increased risk of heart failure compared to normal weight individuals.