Articles tagged with Obesity
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A new study led by William Kerr of SUNY Upstate Medical University found that SHIP1 inhibition improved metabolic phenotypes in mice fed a high-fat diet. The results showed that SHIP1 inhibition prevented excess weight gain, improved blood sugar control, and reduced inflammation in adipose tissue.
Sarcopenic obesity is a combination of low muscle mass and high fat mass, common in older adults. Research suggests that public health strategies are needed to prevent and treat this condition, which increases risks of mobility issues, metabolic disease, and mortality.
A study published in Cancer Research found that obese women who lost weight through diet or exercise significantly lowered levels of angiogenesis-related proteins in their blood. This suggests a potential link between weight loss and reduced cancer risk, although further research is needed to confirm the association.
Researchers aim to create more small, energy-burning fat cells that enable the body to use fat as fuel rather than store it as unhealthy padding. By studying the protein HDAC9, they hope to develop new treatments for obesity-related diseases like diabetes and cardiovascular disease.
A large international study found that being overweight or obese significantly increases the risk of dying prematurely, with a BMI of 40.0-<60.0 kg/m2 associated with nearly three-fold risk.
Research found blood glucose health deteriorating in obese adults, despite progress in lowering blood pressure and cholesterol levels. The study suggests controlling weight in obese adults to reduce the risk of developing Type 2 diabetes and cardiovascular complications.
A new mouse study shows that diet response is highly individualized and dependent on genetic composition. The researchers found that different mice strains responded differently to various diets, including Western, Mediterranean, and ketogenic diets.
A new York University study suggests that fat cells can promote breast cancer growth in obese individuals but prevent it in lean people. Exercise has been shown to counteract the life-threatening effects of obesity and even completely prevent breast cancer growth.
A study of 3.9 million adults found that obesity is associated with an increased risk of premature death, with the greatest effect in men. The risks of coronary heart disease, stroke, respiratory disease, and cancer are all increased, resulting in a three-fold greater excess risk of premature death among men compared to women.
A new study by Michigan State University neuroscientist Alexander Johnson finds that obese mice are more likely to overeat in response to environmental cues due to altered brain responses. The study suggests a psychological and neurobiological account for why obese individuals may be vulnerable to food triggers.
A new study by Michigan State University researchers found that obese mice are more likely to overeat in response to environmental cues, driven by changes in the brain. The study suggests a neurobiological account for why obese individuals may be particularly vulnerable to food signals.
A brain pathway in the medial prefrontal cortex plays a critical role in restraining from food temptation, suggests a new study. The researchers found that individual neurons in this region become activated in response to both 'go' and 'stop' cues, enabling control over impulsive eating behavior.
Research shows that as body mass index increases, so does the growth and spread of multiple myeloma. Fat cells from obese or morbidly obese patients secrete inflammatory proteins that contribute to tumor progression. This study suggests a new treatment approach, tailoring drugs based on a patient's BMI.
Researchers discovered that inadequately hydrated obese individuals tend to have a higher BMI, suggesting water intake plays a crucial role in weight management. The study also highlights the importance of staying hydrated for overall health regardless of body mass index.
Patients who underwent bariatric surgery experienced a reversal of premature aging, characterized by longer telomeres and reduced inflammation. Two years after surgery, patients had telomeres that were 80% longer than before the procedure.
A national study developed by a University of Missouri researcher led to the creation of five pilot programs targeting lesbian and bisexual communities. The initiatives focused on lifestyle changes such as increased physical activity, healthier eating habits, and mindfulness-approach to improve overall health outcomes.
A landmark study suggests that culturally tailored weight-and-fitness interventions are effective in helping lesbian and bisexual women improve health behaviors. The study found that nearly 60% of participants increased their physical activity minutes by 20% and 95% achieved one or more health objectives.
A recent study found that parental diet quality has a significant impact on children's diet quality, with too few vegetables and empty calories being major contributors. Researchers analyzed data from over 600 parent-child duos and found that parents had better diet scores than kids, but only by a small margin.
Researchers at Massachusetts General Hospital found a link between obesity and decreased response to chemotherapy in pancreatic cancer patients. Inhibiting the AT1 signaling pathway may be an effective strategy to overcome this obstacle.
A study of 290 women found that lifestyle intervention preceding fertility treatment improved natural conception rates, particularly in anovulatory women. However, the intervention had no significant effect on fertility treatment outcomes or overall live birth rates in any subgroup.
A recent study published in ACS' Journal of Proteome Research found that calorie restriction can help delay age-related disorders. The researchers discovered that mice on low-calorie diets had reduced oxidative stress, improved lipid metabolism, and altered gut-microbial metabolites compared to those on high-calorie diets.
A new study published in PLOS Medicine found that obesity in early adulthood is associated with a significantly increased risk of developing multiple sclerosis. The research, led by Dr. Brent Richards, used Mendelian randomization to investigate the link between genetically determined obesity and MS risk. The study found that an averag...
A Brazilian birth cohort study found that life-course overweight and obesity significantly increase the risk of unfavorable periodontal outcomes. The study suggests a cluster effect, where excess weight and unhealthy habits together exacerbate periodontitis risk.
A randomized study found that highly structured nutrition plans lead to the most significant impact on A1C, body weight, and lipid profiles. Participants reduced A1C by an average of 0.67% and lost 3.5Kg over 16 weeks without changing medications or exercise.
Eating irregularly is linked to a higher risk of metabolic syndrome and obesity. The authors argue that considering the timing of meals alongside dietary choices could lead to better public health outcomes. Research highlights the importance of studying chrono-nutrition and its impact on our internal body clocks.
Research by Thomas Willnow found that SORLA regulates insulin signaling, leading to increased fat accumulation and obesity in mice. Reducing SORLA levels protected against diet-induced obesity.
Researchers at Carnegie Mellon University and the University of Pennsylvania found that online food ordering reduced calorie counts by about 10 percent when menus used traffic light color-coded labels, numeric labels, or a combination of both. The study suggests that clearer information helps consumers make healthier choices.
A recent study published in the European Heart Journal found that teenage body weight is a significant predictor of heart failure risk in adulthood. Men with a BMI of 20 or higher had a significantly increased risk of heart failure, with the risk rising steeply with increasing body weight.
Research of over 1.6 million Swedish men reveals that being overweight as a teenager significantly increases the risk of heart failure in early middle age. The study found a nearly ten-fold increased risk for those with a BMI of 35 or more, emphasizing the importance of maintaining a healthy weight from an early age.
A study published in Nutrition & Diabetes has found that overeating reduces levels of the hormone uroguanylin, which signals feelings of fullness in the brain. When mice were overfed, their small intestines stopped producing this hormone, leading to increased eating behavior.
A new study published in Diabetes suggests that age and dopamine receptors may play a role in the preference for sweet foods in people with normal weight, but not in those with obesity. The researchers found that insulin resistance could contribute to the altered brain response in obese individuals.
Studies find individuals with ADHD or obesity prefer smaller immediate rewards over larger future rewards, leading to potential new treatments for these conditions. The research suggests a connection between the inability to delay gratification and addictive disorders.
A systematic review and meta-analysis of randomized clinical trials found that phentermine-topiramate and liraglutide were associated with the highest odds of achieving at least 5% weight loss. The study included nearly 30,000 overweight or obese adults and identified the efficacy of five FDA-approved long-term weight loss agents.
Researchers have found that copper helps regulate fat burning by blocking an enzyme that prevents fat breakdown when it's not needed. Without enough copper, fat builds up in cells, leading to obesity and diabetes. The study suggests a new role for copper in metabolism and opens the door to new therapeutic approaches.
A recent study found that patients with rheumatoid arthritis who are obese and smoke have a lower chance of achieving sustained remission after treatment. Encouraging patients to quit smoking and maintain a healthy weight could improve their symptoms. The findings highlight the importance of lifestyle factors in managing the disease.
A Yale-led team of researchers identified how altered gut microbiota causes obesity by stimulating insulin secretion through acetate production. The study suggests a causal link between changes in the diet, gut microbiota, and increased food intake, driving a positive feedback loop.
Dr. Frank G. Moody, a pioneer in weight loss surgery, has been honored by the American Surgical Association for his contributions to advancing surgical care. He was recognized for his work in promoting weight loss surgery and his leadership in developing comprehensive bariatric programs.
A new study from the Cornell Food & Brand Lab found that women who recall their parents commenting on their weight are more prone to being overweight and less satisfied with their weight as adults. Commenting on a daughter's weight can have a negative impact later in life, damaging body image regardless of weight.
The prevalence of obesity in the US has increased among women, with a significant rise between 2005 and 2014, while rates for men have remained stable. Obesity affects over 38% of adults in the US, with class 3 obesity affecting around 7.7% of both sexes.
Researchers found a genetic variation linked to food addiction in Asian-American college students, who were more likely to crave carbohydrates and fast food. The study's findings suggest that targeting addictive behavior in individuals with the DRD2 A1 variant could lead to personalized approaches for promoting healthier eating habits.
Researchers have identified a protein called TST that helps detoxify waste products in fat cells, leading to improved insulin sensitivity and reduced weight gain in obese mice. The study's findings suggest a potential new approach to treating type 2 diabetes associated with obesity.
A University of Georgia study finds that people's definitions of moderation vary based on their perception of food, leading to inconsistent behavior. The research suggests that the concept of moderation can be misleading for weight management and obesity prevention.
Researchers identify epigenomic changes that contribute to the development of type 2 diabetes in obese individuals. These changes are associated with inflammation and trigger insulin resistance, highlighting the importance of epigenetic regulation in metabolic diseases.
Eating a Mediterranean diet rich in vegetable fats like olive oil and nuts has been shown to have little effect on bodyweight or waist circumference compared to a low-fat diet. The study suggests that current health guidelines recommending low-fat diets may be creating unnecessary fear of healthy fats.
A new study presented at the European Obesity Summit found that a procedure-free gastric balloon, called Elipse, is safe and leads to similar weight loss as other balloon procedures. The device, swallowed and excreted over 4 months, resulted in significant weight loss, improvements in blood sugar control, and quality of life.
A study by Dr Anu Molarius found that obesity rates increased from 13% to 17% among women and 12% to 17% among men between 2000 and 2012. The prevalence of obesity was highest among middle-aged individuals with a middle level education.
A study of nearly 49,000 obese patients found that bariatric surgery significantly lowers mortality rates, with a 57% reduction in all-cause deaths compared to non-surgical patients. Cardiovascular disease and cancer were the leading causes of death in both groups.
A small study suggests that obese UK diabetics who undergo bariatric surgery can save the NHS around £95,000 over their lifetime due to reduced medication costs. The study found that 44 patients with type 2 diabetes who no longer required treatment after surgery resulted in significant outpatient and inpatient savings.
Only 17 weight management apps have been developed by certified health organisations or universities, with no published data on their effectiveness. Researchers recommend transferring professionally-designed online materials into app form to ensure content-quality and evidence-based weight control.
African American men with high West African genetic ancestry have lower waist circumference and waist-hip ratio, indicating reduced central adiposity. In contrast, African American women do not show a similar association, suggesting that genes from West Africa may offer protection against obesity in men but not women.
A recent study published in Frontiers in Genetics found that black men with more genetic variants descended from West Africa tend to have a lower waist circumference and waist-hip ratio, indicating less central adiposity. This suggests that certain genes may provide partial protection against obesity.
Researchers found that women face a range of barriers to physical activity, including physical challenges and psychological concerns, which vary by weight. A new study suggests that a one-size-fits-all approach may not be effective in helping women become more physically active.
A whole-person perspective is needed to accurately assess obesity severity, considering factors like muscle mass and ethnicity. The review article suggests staging obesity treatment from stage 0 to stage 4, with intensive lifestyle modification being crucial for preventing disease progression.
A study examining obese older adults in nursing homes found that those with higher body mass indexes were more likely to be admitted to facilities with deficiencies in care. Nearly 22% of admitted residents were obese, with morbidly obese individuals facing even greater challenges.
A nationwide study found that obese young adults are at risk for chronic kidney disease due to undetected albuminuria, with Mexican Americans and blacks showing higher rates. The study suggests that healthcare providers should test for kidney damage in obese young adults, emphasizing the importance of prevention through lifestyle changes.
A recent study by Ben-Gurion University of the Negev found that obese air passengers experience shame and humiliation due to stares, not just confined spaces. Researchers recommend alternative accommodations and approaches to make flights more comfortable for extra-large passengers.
A study found that urban neighborhoods with more walkable design have lower rates of overweight, obesity, and diabetes compared to less walkable areas. The prevalence of these conditions increased in less walkable neighborhoods between 2001 and 2012.
A new treatment option is being developed to help people with obesity - swallowing gas-filled balloons that reduce hunger and increase feelings of fullness. Patients using the Obalon 6-month balloon system lost an average of 6.81 percent of their weight, compared to 3.59 percent in the control group.
A new study found that highly walkable Ontario neighborhoods experienced a drop in diabetes cases, while less walkable areas saw a rise in obesity rates. The research, led by Dr. Gillian Booth, analyzed 9,000 neighborhoods over a decade and involved 3 million people.
Researchers found that epigenetic modifications in the Igfbp2 gene increase susceptibility to obesity and predict fatty liver disease. Young animals with this modification exhibit impaired glucose metabolism and morbid obesity.