Articles tagged with Obesity
Researchers found nearly all common obesity-related genes lack properties that suggest an evolutionary advantage, contradicting the 'thrifty gene' hypothesis. The study's results suggest a more complex evolution of human health and disease.
A University of Cincinnati study found that gut bacteria influences intestinal mast cells' activation and fat absorption. The research suggests a novel role for the gut microbiome in promoting lipid absorption.
Research reveals that even marginal increases in weight negatively impact female job prospects in service sector jobs. Workplace discrimination against those of 'normal' weight is not new, but women face greater bias, highlighting unrealistic societal expectations and practical implications for employers.
Research suggests that mango supplementation can prevent the loss of beneficial gut bacteria often induced by a high-fat diet. This is achieved through the regulation of gut bacteria in favor of Bifidobacteria and Akkermansia, as well as enhanced short-chain fatty acid production.
A study published in Neurology found that excess weight in women increases the risk of ischemic stroke, while decreasing the risk of hemorrhagic stroke. The research followed over 1.3 million women for 12 years, revealing a significant association between body mass index and stroke subtype.
Researchers found that overweight patients with metastatic kidney cancer had significantly longer survival and decreased risk of death compared to normal-weight counterparts. FASN gene expression was also found to be decreased in obese patients, which could explain their better treatment outcomes.
Researchers investigate how exposure to chemicals inhibits metabolism of fatty and high-sugar foods, contributing to obesity. The team aims to understand how toxicants affect cytochrome P450 enzymes, potentially identifying new targets for pharmaceutical companies.
A CU study reveals that genes may play a significant role in how people perceive their weight, with female participants showing a stronger genetic influence. The research used twin data from the National Longitudinal Study of Adolescent to Adult Health, finding that perceived weight status has a heritability estimate of 0.47.
A study of 1,787 veterans found that those who underwent Roux-en-Y gastric bypass surgery lost an average of 21% of their baseline weight at 10 years after surgery. In comparison, nonsurgical matches experienced a smaller estimated weight loss of around 11-12%.
A global study involving 10.6 million people contradicts a previous finding that being overweight increases longevity, stating that it is instead linked to a higher risk of premature death from coronary heart disease, stroke and respiratory disease. The study's findings have important clinical and public health implications.
Researchers have discovered a new strategy to cultivate beneficial beige fat, which can help ward off obesity and diabetes. By preventing beige fat cells from digesting their own mitochondria, the intervention successfully protected against obesity and pre-diabetic symptoms in mice, raising hopes for future applications in human patients.
Researchers discovered a metabolic enzyme that acts as a gatekeeper for the innate immune system, triggering strong inflammatory responses against harmful bacteria. This finding may help explain why obesity, Type 2 diabetes, and coronary artery disease are often accompanied by inflammation.
A new study found no clear common characteristic of microbe populations in obese individuals, disappointing those hoping for a solution to weight loss through gut bacteria alteration. The researchers suggest that a more complex relationship exists between the microbiome and health, warranting further investigation.
A Johns Hopkins study of over 13,000 participants found that severe obesity is a standalone high-risk factor for heart failure, but not other types of heart disease. Morbidly obese individuals were nearly fourfold more likely to develop heart failure even after controlling for risk factors such as high blood pressure and diabetes.
A study published by the American Chemical Society found that citrus flavanones, a type of antioxidant, can reduce oxidative stress and inflammation caused by high-fat diets. This reduction leads to lower levels of cell-damage markers in the blood and liver, as well as reduced fat accumulation and damage in the liver.
A study by University of Missouri researchers found that linagliptin provided protection against arterial stiffness in overweight female mice fed a western diet. The medication works by blocking the enzyme dipeptidyl peptidase-4 and has been shown to offer protection against vascular inflammation and oxidative stress.
A recent study challenges the concept of 'healthy obesity,' revealing nearly identical gene expression changes in obese individuals with varying levels of insulin sensitivity. The research suggests that vigorous health interventions may be necessary for all obese individuals, regardless of their metabolic health status.
Researchers at Thomas Jefferson University found alarming rates of obesity and high blood pressure readings among urban student-athletes, similar to the general adolescent population. The study suggests that participation in athletics does not protect against these conditions.
A longitudinal study published in PLOS Medicine found a strong association between the duration of adulthood overweight and obesity and an increased risk of developing various types of cancer. For every ten-year increase in adulthood overweight duration, the risk of all obesity-related cancers was associated with a 7% increase.
Researchers at Boston University School of Medicine discover a novel protein called PTRF linked to type 2 diabetes and insulin resistance. The study finds that most obese individuals develop insulin resistance despite having normal fat cells.
Researchers found that a specific gene mutation linked to impulsive behavior also protects carriers from obesity and insulin resistance, which are risk factors for type 2 diabetes. The study suggests that lower testosterone levels in these individuals actually increase insulin sensitivity.
A study at Columbia University's Mailman School of Public Health found that obesity prevalence increased from 22% to 32% among cancer survivors between 1997 and 2014. Colorectal and breast cancer survivors, as well as non-Hispanic blacks, were particularly affected.
A study found that nearly half of US adults consume sugar-sweetened beverages daily, and two-thirds eat discretionary foods like cookies and candy. Despite supermarket access, these unhealthy choices persist, suggesting a need to address junk food marketing and nutrition education.
A Georgia State University researcher is investigating how changes in intestinal bacteria may lead to obesity and metabolic syndrome. He aims to understand the role of dietary fiber in altering gut bacteria and promoting inflammation.
Research finds women's body dissatisfaction decreasing over time, while men's remains relatively constant. The study suggests a positive trend towards increased body diversity and acceptance among women, potentially influenced by the rise of body positivity movement.
A Buck Institute study found a key protein involved in nutrient sensing differs between male and female mice, impacting diabetes risk. Boosting this protein reduces obesity and insulin resistance in male mice.
Research reveals that obese individuals' brains display differences in white matter similar to those in lean individuals ten years older, from middle-age onwards. Obesity may affect the onset and progression of brain aging, with potential implications for health and cognitive abilities.
Researchers at Charité - Universitätsmedizin Berlin have successfully treated two patients with rare genetic disorders causing severe hyperphagia. The new drug treatment, which targets the satiety center in the brain, resulted in significant weight loss and normalization of hunger feelings in both patients.
A study published in JAMA Internal Medicine found that consuming more plant-based protein was associated with a lower risk of death from all causes and cardiovascular disease. The researchers observed significant health benefits when substituting animal protein with plant protein, particularly from processed red meat.
A recent study on 'The Biggest Loser' television series found that participants regained much of the weight they lost, with suppressed metabolism. Experts say a 5-15% weight loss is unlikely to lead to such large effects on metabolism and emphasize the importance of long-term lifestyle changes.
Researchers have created a new framework called 'nutritional geometry' that considers how mixtures of nutrients influence health and disease. The approach is hoped to assist in better understanding and managing obesity by focusing on nutrient balance rather than single nutrients.
A study by University of Adelaide researchers found that meat consumption contributes to global obesity at the same extent as sugar, with protein in meat digested later and converted to excess energy. The study suggests dietary guidelines may need to advise eating less meat alongside reducing sugar intake.
A study published in Frontiers in Cellular Neuroscience found that a high-fat diet, particularly one rich in saturated fats like lard, can impair cognitive function and lead to increased hunger. In contrast, consuming fish oil has been shown to support brain health and regulate appetite.
A new study published in Cell Reports explains how a blood pressure hormone system can promote obesity. The renin-angiotensin system (RAS) controls energy balance and metabolic rate, with elevated brain RAS increasing energy expenditure and weight loss, while peripheral RAS suppressing resting metabolism and increasing weight gain.
A new study found that lifestyle factors such as obesity and smoking are associated with a worse quality of life rating for Acute Respiratory Distress Syndrome (ARDS) patients. The study suggests that incorporating smoking cessation education into the critical care setting may be beneficial in improving patient outcomes.
Severely obese patients undergoing weight loss surgery are at higher risk of fractures before and after surgery. The study suggests that guidelines should be followed on patient adherence to dietary supplements and physical activity to reduce fracture risk.
A recent study identified a genetic variant associated with higher BMI levels and increased efficiency of fat storage among Samoans. This 'thrifty' variant, found on chromosome 5, is linked to the islands' high obesity rates and may have evolved as an adaptation to food scarcity in ancient times.
A large study of nearly 21,000 people in Jilin Province found that being overweight or obese was associated with regular meat consumption, having ever been married, and getting less than 7 hours of sleep per night. The prevalence of obesity and overweight was higher among older adults, particularly those aged 55-64 and 65-79.
A recent study published in the journal Obesity found that severely obese women's brain activity differs from lean counterparts when it comes to responding to food cues. Despite reporting fullness, their brains continued to react similarly to hungry states, with sustained activation in reward centers.
A new study led by William Kerr of SUNY Upstate Medical University found that SHIP1 inhibition improved metabolic phenotypes in mice fed a high-fat diet. The results showed that SHIP1 inhibition prevented excess weight gain, improved blood sugar control, and reduced inflammation in adipose tissue.
Sarcopenic obesity is a combination of low muscle mass and high fat mass, common in older adults. Research suggests that public health strategies are needed to prevent and treat this condition, which increases risks of mobility issues, metabolic disease, and mortality.
A study published in Cancer Research found that obese women who lost weight through diet or exercise significantly lowered levels of angiogenesis-related proteins in their blood. This suggests a potential link between weight loss and reduced cancer risk, although further research is needed to confirm the association.
Researchers aim to create more small, energy-burning fat cells that enable the body to use fat as fuel rather than store it as unhealthy padding. By studying the protein HDAC9, they hope to develop new treatments for obesity-related diseases like diabetes and cardiovascular disease.
A large international study found that being overweight or obese significantly increases the risk of dying prematurely, with a BMI of 40.0-<60.0 kg/m2 associated with nearly three-fold risk.
Research found blood glucose health deteriorating in obese adults, despite progress in lowering blood pressure and cholesterol levels. The study suggests controlling weight in obese adults to reduce the risk of developing Type 2 diabetes and cardiovascular complications.
A new mouse study shows that diet response is highly individualized and dependent on genetic composition. The researchers found that different mice strains responded differently to various diets, including Western, Mediterranean, and ketogenic diets.
A new York University study suggests that fat cells can promote breast cancer growth in obese individuals but prevent it in lean people. Exercise has been shown to counteract the life-threatening effects of obesity and even completely prevent breast cancer growth.
A study of 3.9 million adults found that obesity is associated with an increased risk of premature death, with the greatest effect in men. The risks of coronary heart disease, stroke, respiratory disease, and cancer are all increased, resulting in a three-fold greater excess risk of premature death among men compared to women.
A new study by Michigan State University neuroscientist Alexander Johnson finds that obese mice are more likely to overeat in response to environmental cues due to altered brain responses. The study suggests a psychological and neurobiological account for why obese individuals may be vulnerable to food triggers.
A new study by Michigan State University researchers found that obese mice are more likely to overeat in response to environmental cues, driven by changes in the brain. The study suggests a neurobiological account for why obese individuals may be particularly vulnerable to food signals.
A brain pathway in the medial prefrontal cortex plays a critical role in restraining from food temptation, suggests a new study. The researchers found that individual neurons in this region become activated in response to both 'go' and 'stop' cues, enabling control over impulsive eating behavior.
Research shows that as body mass index increases, so does the growth and spread of multiple myeloma. Fat cells from obese or morbidly obese patients secrete inflammatory proteins that contribute to tumor progression. This study suggests a new treatment approach, tailoring drugs based on a patient's BMI.
Researchers discovered that inadequately hydrated obese individuals tend to have a higher BMI, suggesting water intake plays a crucial role in weight management. The study also highlights the importance of staying hydrated for overall health regardless of body mass index.
Patients who underwent bariatric surgery experienced a reversal of premature aging, characterized by longer telomeres and reduced inflammation. Two years after surgery, patients had telomeres that were 80% longer than before the procedure.
A national study developed by a University of Missouri researcher led to the creation of five pilot programs targeting lesbian and bisexual communities. The initiatives focused on lifestyle changes such as increased physical activity, healthier eating habits, and mindfulness-approach to improve overall health outcomes.
A landmark study suggests that culturally tailored weight-and-fitness interventions are effective in helping lesbian and bisexual women improve health behaviors. The study found that nearly 60% of participants increased their physical activity minutes by 20% and 95% achieved one or more health objectives.
A recent study found that parental diet quality has a significant impact on children's diet quality, with too few vegetables and empty calories being major contributors. Researchers analyzed data from over 600 parent-child duos and found that parents had better diet scores than kids, but only by a small margin.
Researchers at Massachusetts General Hospital found a link between obesity and decreased response to chemotherapy in pancreatic cancer patients. Inhibiting the AT1 signaling pathway may be an effective strategy to overcome this obstacle.
A study of 290 women found that lifestyle intervention preceding fertility treatment improved natural conception rates, particularly in anovulatory women. However, the intervention had no significant effect on fertility treatment outcomes or overall live birth rates in any subgroup.
A recent study published in ACS' Journal of Proteome Research found that calorie restriction can help delay age-related disorders. The researchers discovered that mice on low-calorie diets had reduced oxidative stress, improved lipid metabolism, and altered gut-microbial metabolites compared to those on high-calorie diets.