Articles tagged with Obesity
Researchers found that young adults taught to weigh themselves daily and make small changes in diet and exercise had significantly reduced average weight gain over three years. The large change strategy led to even more effective weight loss results.
A randomized clinical trial found that 25% calorie restriction over two years improved mood, reduced tension, and enhanced general health and sexual drive in healthy adults. The study suggests that calorie restriction may provide some benefits for nonobese individuals, contradicting previous concerns about potential negative effects.
A McMaster University research team is examining how environmental factors, such as agricultural practices and toxicants, affect brown adipose tissue activity in individuals with obesity or type-2 diabetes. The studies aim to develop new strategies to enhance BAT activity for treating and preventing these diseases.
Researchers have developed nanoparticles that deliver antiobesity drugs directly to fat tissue, transforming white adipose tissue into brown and stimulating angiogenesis. The treatment resulted in a 10% weight loss in mice without adverse side effects.
A study in Mexico reveals that noncommunicable diseases, such as type 2 diabetes and hypertension, are a growing threat to maternal survival. The reclassification of 1214 deaths identified 13% more maternal deaths than previously thought, with indirect causes accounting for 12.2 deaths per 100,000 live births.
A study of 33,588 Danish twins found psoriasis associated with type 2 diabetes and obesity, with a possible common genetic cause. The prevalence of psoriasis was higher among individuals with obesity, suggesting a potential link between the two conditions.
A faith-based health promotion program, Abuelas en Acción, successfully motivated older Latinas to adopt healthier lifestyles by integrating spiritual and family values. Participants showed significant improvements in physical activity, nutrition, and stress management.
A study published in Nature Communications found that visceral fat is strongly linked to metabolic disease and insulin resistance. Researchers identified the regulatory molecule TRIP-Br2 as a key player in this process, which could lead to potential therapeutic agents against obesity.
A pilot study examining southwest tribal elders found moderate vascular risk despite hypertension treatment, highlighting the need for culturally fair instruments and biomarkers. Cognitive and depressive symptoms were also significant factors in the research results.
Researchers found that benzyl butyl phthalate (BBP) causes larger lipid droplet accumulation in cells, potentially leading to obesity. The study's results suggest a possible link between BBP exposure and adipogenesis, a process contributing to fat cell development.
A 2-year study found that bupropion (Wellbutrin) is the only antidepressant to induce modest weight loss, while others lead to varying degrees of weight gain. Nonsmokers on bupropion lost an average of 2.4 pounds, compared to a 4.6-pound gain on fluoxetine.
A new study demonstrates that a build-up of fat around the waist can cause more serious complications than obesity in the development of non-alcoholic fatty liver disease (NAFLD). Non-obese patients with a large waist circumference are at risk of NAFLD complications, according to the research. The study highlights the need for addition...
Scientists have discovered a potential method for battling obesity by stimulating brown fat in genetically predisposed mice, which may help treat metabolic syndrome and its related health issues. The study found that increasing heat production in the fatty tissue improved weight management and glucose control.
Research published in Diabetologia found that people with diabetes face reduced overall life expectancy and higher numbers of years living with disability compared to those without diabetes. The study estimated a loss of 3-9 years of life expectancy and 8-9 years of disability-free life expectancy for men and women with diabetes.
A recent study published in eNeuro found that overweight individuals are more prone to choosing unhealthy foods when presented with real options, unlike their lean counterparts. The researchers also discovered an association between impulsivity and consumption of unhealthy foods in overweight participants.
A study published by the University of Texas M.D. Anderson Cancer Center found a link between obesity and kidney cancer recurrence, with leptin receptors playing a key role in tumor formation. The research suggests that obesity may also impact prognosis for patients with renal cell carcinoma.
A Finnish group found that vascular endothelial growth factor B (VEGFB) can increase the density of adipose tissue vasculature, reducing inflammation and improving insulin function. Blocking the VEGFR1 receptor enhances the treatment effect by stimulating catabolic processes in adipose tissue.
A study found that a gene variation linked to obesity also affects food intake regulation by altering the expression of nearby genes. Reduced expression of these genes led to increased food intake and weight gain in mice.
Research published in The FASEB Journal suggests that maternal obesity and poor nutrition during pregnancy can impair the fertility of female offspring. The study found that daughters whose mothers ate a high-fat, high-sugar diet had fewer eggs than normal.
A multi-site clinical trial is assessing the safety and effectiveness of bariatric arterial embolization in treating patients with morbid obesity. The procedure targets ghrelin, reducing hunger sensation and promoting weight loss.
New research reveals dramatic worldwide increases in body-mass index (BMI) and type 2 diabetes, with American Samoa and independent Samoa exhibiting exceptionally high prevalence of both conditions. The studies attribute the rise to factors such as globalization, changing food habits and lifestyles.
The Royal Society of Public Health advocates for introducing activity equivalent calorie labelling on food packaging to prompt people to be more mindful of their energy consumption and encourage physical activity. Public polling shows that almost half of people find current front-of-pack information confusing, but 53% would positively ...
A world-first study by QUT finds that drugs used to treat nicotine addiction can also reduce sugar cravings and consumption. The study highlights the importance of reevaluating our relationship with sweetened food, and may represent a novel new treatment strategy for obesity.
A study of 2,221 adults with severe obesity who underwent bariatric surgery found that approximately 50-70% experienced clinically significant improvements in pain and physical function over 3 years. Younger age, male sex, and weight loss were associated with greater improvements.
A high-quality protein diet, including lean beef, can improve balance, lower-body strength and walking speed in obese older adults with limited ability to exercise. This study supports the benefits of protein-enhanced meals for fostering improvements in physical function during periods of weight loss.
A pilot study found that mindfulness-based eating awareness training encouraged adolescents to eat healthier and exercise more. While the intervention had some limitations, it showed promise in reducing weight gain risk and improving physical activity levels.
A three-year study found that liraglutide can help nondiabetic overweight and obese adults lose weight and reduce their risk of developing Type 2 diabetes. After three years, 66% of participants taking liraglutide no longer had prediabetes.
In a clinical trial of 100 obese men, researchers found that adding testosterone treatment to calorie restriction resulted in increased fat loss and preserved muscle mass. The study suggests that testosterone treatment may be a useful adjunct to weight loss in obese men with low testosterone levels.
A safe, minimally invasive treatment called bariatric arterial embolization (BAE) has been shown to lead to sustained weight loss in severely obese people. BAE targets the stomach's hunger hormone production, reducing appetite and resulting in significant weight loss.
A new minimally invasive weight loss treatment called bariatric arterial embolization has shown safety and efficacy in a clinical trial, initiating weight loss and reducing hunger levels. The procedure targets the production of ghrelin, a hormone controlling hunger, with promising results in sustaining weight loss.
A new study from Intermountain Medical Center and Johns Hopkins Hospital found that abdominal obesity, or having an apple-shaped body, is a strong predictor of serious heart disease in diabetic patients. Waist circumference was also shown to be a stronger predictor of left ventricular dysfunction than total body weight or BMI.
A Paleolithic-type diet improved insulin sensitivity, reduced abdominal adiposity and body weight in obese postmenopausal women. The diet high in polyunsaturated fatty acids may have long-term beneficial effects on obesity-related disorders.
A study found that oxytocin nasal spray decreases impulsive behavior in overweight men, allowing for better self-control and reduced food intake. The treatment showed promising results with minimal side effects, suggesting a potential new approach to treating obesity.
Steroid medications like prednisolone suppress brown fat's activity, leading to weight gain and obesity. Researchers found that steroid use increases energy storage from food instead of burning it through brown fat.
Research from Australia suggests that women with PCOS report a higher prevalence of asthma, which is also linked to excess weight. The study found that PCOS status and body mass index were independently associated with asthma.
A new study suggests that liraglutide, a diabetes drug, reduces the brain's reward response to high-fat foods, making them less desirable. This effect may be beneficial for individuals with Type 2 diabetes who tend to overindulge in fatty foods as a coping mechanism.
Whey protein diet participants lost the most weight and experienced reduced hunger and glucose spikes compared to other diets. The study found that a high-protein breakfast containing whey protein induced greater satiety and reduction of glucose spikes after meals.
A new study found that combining a temporary intestinal bypass device with the drug liraglutide improves diabetes control and weight loss in patients. The combination treatment resulted in significant weight loss (12.8 kg) and improved glycated hemoglobin levels compared to other treatments.
A new meta-analysis reveals a clear correlation between higher BMI, waist circumference, and the risk of heart failure. Overweight individuals had a 35% increased risk of heart failure compared to normal weight individuals.
A new study suggests that sleeve-IT surgery is an effective treatment for mild obesity-related Type 2 diabetes, with improved glycemic control and significant weight loss. The procedure resulted in 100% of patients achieving glycemic control compared to 8% of those treated clinically.
A global study found that people living in densely populated and walkable neighborhoods with interconnected streets got up to 90 minutes of physical activity weekly. Four environmental attributes stood out as having the most impact on physical activity: net residential density, intersection density, number of parks and public transit d...
A new study suggests that polycystic ovary syndrome (PCOS) is associated with asthma and excess weight in reproductive-age women. The research found a higher prevalence of asthma among PCOS patients compared to those without the condition, as well as an increased risk of asthma among overweight and obese individuals.
African-American infants who feed more vigorously at 1 month of age have higher weight at 4 months, a potential early indicator of obesity risk. Researchers found that stronger sucking skills were associated with greater weight gain from birth to 4 months.
An ongoing clinical trial found that older overweight and obese adults with Type 2 diabetes can improve glucose control, body composition, and physical function through healthier diets and regular exercise. The study's results suggest that lifestyle changes may be a viable treatment option for this age group.
Elderly adults who live in homes with cooler temperatures during the winter season tend to have smaller waistlines compared to those living in warmer environments. Researchers found that safe cold exposure can be an effective preventive measure against obesity.
Researchers found that metabolically healthy obese individuals tend to be younger and more likely to engage in physical exercise. They were also less likely to smoke or drink heavily. Metabolically unhealthy individuals, on the other hand, had factors such as high cholesterol, age, and smoking status associated with their health.
The world is experiencing a shift in global body mass index (BMI) trends, with more people becoming obese than underweight. By 2025, around a fifth of adults worldwide are projected to be obese, with over 6% of men and 9% of women expected to be severely obese.
Researchers have identified 10 oft-repeated errors in obesity studies, including pre-post differences between groups, cluster randomized trials, and meta-analysis calculation errors. These flaws can lead to inaccurate weight loss results and undermine the validity of obesity research.
Researchers at Ohio State University have found that deleting microRNA-155 in female mice prevents weight gain on a high-fat diet. The study shows a 56% reduction in obesity and a 74% reduction in fat accumulation.
A new study from Newcastle University found that people who reverse their Type 2 diabetes and keep their weight down remain free of the condition. The research shows that even patients with diabetes for up to 10 years can reverse their condition by removing fat from their pancreas.
A new study by Rice University researchers found that obese women, even those with higher education, are double the risk of depression compared to normal-weight women. The study used a large population-based sample of healthy women and controlled for various factors, including diet and lifestyle.
A study published in Diabetologia found that bariatric surgery significantly improved type 2 diabetes remission rates compared to an intensive lifestyle and medical intervention. Patients with mild-to-moderate obesity experienced greater weight loss, improved glucose control, and reduced need for diabetes medications after RYGB.
Researchers identified O-GlcNAc transferase (OGT) as a key enzyme regulating food intake in mice. Deletion of OGT caused mice to overeat and become obese, suggesting a new treatment target for human obesity.
Researchers discovered a microRNA called miR-181b that controls the function of vessels in adipose tissue, improving insulin sensitivity and glucose levels. The study found that reconstituting this microRNA in obese mice reduced inflammation in adipose tissue, suggesting potential new targets for obesity and diabetes treatment.
A recent study published in JAMA Neurology found that obese women who use oral contraceptives are at a higher risk for cerebral venous thrombosis (CVT), a rare and potentially life-threatening condition. The study also suggests that alternative methods of contraception, such as intrauterine devices, may be safer options for obese women.
The study reveals that TRPV2 is essential for thermogenesis in mouse brown adipose tissue. Without TRPV2, mice exhibit impaired thermogenesis and increased obesity on high-fat diet treatment.
Researchers found that lead exposure during gestation and lactation altered the gut microbiota of adult mice, leading to increased body weight. The study suggests a potential link between early life lead exposure and obesity in adulthood.
Breast cancer is more aggressive and common in obese women due to peritumoral fat facilitating the expansion of cancer stem cells. Researchers found that interactions between tumor cells and immature adipocytes increase cytokine secretion, leading to increased CSCs and metastasis.
A Kansas State University researcher found that an integrated approach to address hot topics like substance use, obesity, and mental health is critical for teen health. The research involved a mixed-methods approach, collecting data from online surveys, community focus groups, and interviews with key individuals.
A team of scientists at the University of Bonn discovered a switch that can convert unwanted white fat cells into energy-burning brown cells by blocking Gq proteins. This breakthrough has significant implications for obesity treatment, as it may lead to the development of pharmaceutical products that target this pathway.