Articles tagged with Obesity
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Researchers found that rutin extracted from mulberries activates brown adipose tissue to mimic cold-induced thermogenesis, enhancing energy metabolism and weight loss. This natural compound was tested on genetically obese mice and diet-induced obesity models, reducing adiposity and improving glucose homeostasis.
A new trial found that offering patients a weight loss programme during a routine consultation is effective, with participants losing an average of 1.43kg more than those in the control group. The intervention was welcomed by patients and took only 30 seconds of physicians' time.
The BMJ Group recommends restoring the correct dietary balance of omega 6 and omega 3 fatty acids to combat soaring obesity rates. The current ratio is 16:1, whereas human evolution suggests a healthier balance of 1:2/1. This imbalance promotes inflammation, white fat tissue, and chronic diseases linked to obesity.
A study published in the Journal of Marketing Research found that people will choose smaller portions of food when they are enticed by the multisensory pleasure of taste, smell, and texture. This approach can lead to positive outcomes for consumer satisfaction and health, while also benefiting profits in the food industry.
Two new papers published in Diabetologia found a 26% reduction in T2D risk among participants who achieved 11.25 MET hours/week, more than twice the recommended minimum. The studies also suggest that exercising after meals can deliver significant additional health benefits.
A recent review and analysis of published studies found low-to-moderate evidence that dietary and exercise interventions can improve physical function and quality of life in older adults with obesity. The study included 405 adults aged over 60 years, highlighting the need for well-designed trials to address obesity in this population.
Individuals with binge-eating disorder have a 2.5-times increased risk of an endocrine disorder and a 1.9-times increased risk of a circulatory system disorder. The study highlights the importance of accurate screening and detection to improve treatment outcomes for those affected.
A Cleveland Clinic study found that a whole grain diet significantly lowers the risk of cardiovascular disease in overweight and obese adults under 50. Participants saw a three-fold improvement in diastolic blood pressure, reducing heart disease risk by nearly one-third.
Severely obese adults who underwent bariatric surgery maintained their working status and experienced decreased impairment due to health while working. However, there was a small increase in unemployment over time.
Research suggests that mutations in the FTO gene and variants of the dopamine D2 receptor gene increase the risk of developing obesity and diabetes. The study found that individuals with both genetic alterations had a higher percentage of body fat, more abdominal fat, and lower insulin sensitivity.
Two new papers published in Diabetologia found a 26% reduction in T2D risk among participants who achieved moderate activity levels, with benefits increasing at higher activity levels. Timing of physical activity also played a role, with exercising after meals delivering greater health benefits.
Obese women who receive bariatric surgery before becoming pregnant have lower rates of cesarean sections and larger babies compared to those who don't. The study found a significant decrease in cesarean deliveries among women who underwent bariatric operations, with only 1% vs 38% in obese women without the procedure.
Researchers discovered a chemical called Beta-LGND2 that converts white fat to brown fat, increasing metabolism and facilitating weight loss in mice. This breakthrough could lead to new treatments for obesity and metabolic diseases.
Researchers at Scripps Research Institute have identified a new therapeutic target for obesity and type 2 diabetes, IP6K1. The protein promotes fat accumulation by slowing down the breakdown of fat and enhancing weight gain in animal models.
A high-protein diet eliminates improvements in insulin sensitivity after weight loss in obese postmenopausal women. Women who consumed more protein lost less lean tissue, but the total difference was only about a pound.
A study by University of York psychologists found that perceiving oneself as obese triggers lower body satisfaction in females compared to males. Brain activity monitoring revealed a link between body perception and emotional processes, shedding light on eating disorder vulnerabilities.
Researchers at Oregon State University have identified how xanthohumol works and why it has promise in addressing high cholesterol, blood sugar, obesity, and other issues of metabolic syndrome. Xanthohumol may be used as a supplement or prescription drug to address these disorders.
A review of the current knowledge on the causes of type 2 diabetes and obesity reveals a complex interplay between genetic and environmental factors. The study highlights the importance of epigenomic changes, such as DNA methylation and histone modifications, in modulating gene expression and disease risk.
Professional baseball players have seen a significant increase in weight and obesity over the last quarter century. The majority of athletes were within the normal BMI range for over 100 years, but around 1991, their average BMI began to rise, with nearly 80% now falling into the overweight or obese category.
Recent studies suggest that consuming red raspberries may help reduce weight gain and improve motor function. Animal models showed significant reductions in weight gain and improved motor skills with raspberry supplementation, potentially due to the presence of phytochemicals like ellagic acid and quercetin.
A new study found that people with a defective gene variant prefer high-fat foods over sugary ones, contributing to weight gain. Researchers tested participants with lean, obese, and MC4R-defective genes, showing a link between genetic variants and food choice.
Researchers found nearly all common obesity-related genes lack properties that suggest an evolutionary advantage, contradicting the 'thrifty gene' hypothesis. The study's results suggest a more complex evolution of human health and disease.
A University of Cincinnati study found that gut bacteria influences intestinal mast cells' activation and fat absorption. The research suggests a novel role for the gut microbiome in promoting lipid absorption.
Research reveals that even marginal increases in weight negatively impact female job prospects in service sector jobs. Workplace discrimination against those of 'normal' weight is not new, but women face greater bias, highlighting unrealistic societal expectations and practical implications for employers.
Research suggests that mango supplementation can prevent the loss of beneficial gut bacteria often induced by a high-fat diet. This is achieved through the regulation of gut bacteria in favor of Bifidobacteria and Akkermansia, as well as enhanced short-chain fatty acid production.
A study published in Neurology found that excess weight in women increases the risk of ischemic stroke, while decreasing the risk of hemorrhagic stroke. The research followed over 1.3 million women for 12 years, revealing a significant association between body mass index and stroke subtype.
Researchers found that overweight patients with metastatic kidney cancer had significantly longer survival and decreased risk of death compared to normal-weight counterparts. FASN gene expression was also found to be decreased in obese patients, which could explain their better treatment outcomes.
Researchers investigate how exposure to chemicals inhibits metabolism of fatty and high-sugar foods, contributing to obesity. The team aims to understand how toxicants affect cytochrome P450 enzymes, potentially identifying new targets for pharmaceutical companies.
A CU study reveals that genes may play a significant role in how people perceive their weight, with female participants showing a stronger genetic influence. The research used twin data from the National Longitudinal Study of Adolescent to Adult Health, finding that perceived weight status has a heritability estimate of 0.47.
A study of 1,787 veterans found that those who underwent Roux-en-Y gastric bypass surgery lost an average of 21% of their baseline weight at 10 years after surgery. In comparison, nonsurgical matches experienced a smaller estimated weight loss of around 11-12%.
A global study involving 10.6 million people contradicts a previous finding that being overweight increases longevity, stating that it is instead linked to a higher risk of premature death from coronary heart disease, stroke and respiratory disease. The study's findings have important clinical and public health implications.
Researchers have discovered a new strategy to cultivate beneficial beige fat, which can help ward off obesity and diabetes. By preventing beige fat cells from digesting their own mitochondria, the intervention successfully protected against obesity and pre-diabetic symptoms in mice, raising hopes for future applications in human patients.
Researchers discovered a metabolic enzyme that acts as a gatekeeper for the innate immune system, triggering strong inflammatory responses against harmful bacteria. This finding may help explain why obesity, Type 2 diabetes, and coronary artery disease are often accompanied by inflammation.
A new study found no clear common characteristic of microbe populations in obese individuals, disappointing those hoping for a solution to weight loss through gut bacteria alteration. The researchers suggest that a more complex relationship exists between the microbiome and health, warranting further investigation.
A Johns Hopkins study of over 13,000 participants found that severe obesity is a standalone high-risk factor for heart failure, but not other types of heart disease. Morbidly obese individuals were nearly fourfold more likely to develop heart failure even after controlling for risk factors such as high blood pressure and diabetes.
A study published by the American Chemical Society found that citrus flavanones, a type of antioxidant, can reduce oxidative stress and inflammation caused by high-fat diets. This reduction leads to lower levels of cell-damage markers in the blood and liver, as well as reduced fat accumulation and damage in the liver.
A study by University of Missouri researchers found that linagliptin provided protection against arterial stiffness in overweight female mice fed a western diet. The medication works by blocking the enzyme dipeptidyl peptidase-4 and has been shown to offer protection against vascular inflammation and oxidative stress.
A recent study challenges the concept of 'healthy obesity,' revealing nearly identical gene expression changes in obese individuals with varying levels of insulin sensitivity. The research suggests that vigorous health interventions may be necessary for all obese individuals, regardless of their metabolic health status.
Researchers at Thomas Jefferson University found alarming rates of obesity and high blood pressure readings among urban student-athletes, similar to the general adolescent population. The study suggests that participation in athletics does not protect against these conditions.
A longitudinal study published in PLOS Medicine found a strong association between the duration of adulthood overweight and obesity and an increased risk of developing various types of cancer. For every ten-year increase in adulthood overweight duration, the risk of all obesity-related cancers was associated with a 7% increase.
Researchers at Boston University School of Medicine discover a novel protein called PTRF linked to type 2 diabetes and insulin resistance. The study finds that most obese individuals develop insulin resistance despite having normal fat cells.
Researchers found that a specific gene mutation linked to impulsive behavior also protects carriers from obesity and insulin resistance, which are risk factors for type 2 diabetes. The study suggests that lower testosterone levels in these individuals actually increase insulin sensitivity.
A study at Columbia University's Mailman School of Public Health found that obesity prevalence increased from 22% to 32% among cancer survivors between 1997 and 2014. Colorectal and breast cancer survivors, as well as non-Hispanic blacks, were particularly affected.
A study found that nearly half of US adults consume sugar-sweetened beverages daily, and two-thirds eat discretionary foods like cookies and candy. Despite supermarket access, these unhealthy choices persist, suggesting a need to address junk food marketing and nutrition education.
A Georgia State University researcher is investigating how changes in intestinal bacteria may lead to obesity and metabolic syndrome. He aims to understand the role of dietary fiber in altering gut bacteria and promoting inflammation.
Research finds women's body dissatisfaction decreasing over time, while men's remains relatively constant. The study suggests a positive trend towards increased body diversity and acceptance among women, potentially influenced by the rise of body positivity movement.
A Buck Institute study found a key protein involved in nutrient sensing differs between male and female mice, impacting diabetes risk. Boosting this protein reduces obesity and insulin resistance in male mice.
Research reveals that obese individuals' brains display differences in white matter similar to those in lean individuals ten years older, from middle-age onwards. Obesity may affect the onset and progression of brain aging, with potential implications for health and cognitive abilities.
Researchers at Charité - Universitätsmedizin Berlin have successfully treated two patients with rare genetic disorders causing severe hyperphagia. The new drug treatment, which targets the satiety center in the brain, resulted in significant weight loss and normalization of hunger feelings in both patients.
A study published in JAMA Internal Medicine found that consuming more plant-based protein was associated with a lower risk of death from all causes and cardiovascular disease. The researchers observed significant health benefits when substituting animal protein with plant protein, particularly from processed red meat.
A recent study on 'The Biggest Loser' television series found that participants regained much of the weight they lost, with suppressed metabolism. Experts say a 5-15% weight loss is unlikely to lead to such large effects on metabolism and emphasize the importance of long-term lifestyle changes.
Researchers have created a new framework called 'nutritional geometry' that considers how mixtures of nutrients influence health and disease. The approach is hoped to assist in better understanding and managing obesity by focusing on nutrient balance rather than single nutrients.
A study by University of Adelaide researchers found that meat consumption contributes to global obesity at the same extent as sugar, with protein in meat digested later and converted to excess energy. The study suggests dietary guidelines may need to advise eating less meat alongside reducing sugar intake.
A study published in Frontiers in Cellular Neuroscience found that a high-fat diet, particularly one rich in saturated fats like lard, can impair cognitive function and lead to increased hunger. In contrast, consuming fish oil has been shown to support brain health and regulate appetite.
A new study published in Cell Reports explains how a blood pressure hormone system can promote obesity. The renin-angiotensin system (RAS) controls energy balance and metabolic rate, with elevated brain RAS increasing energy expenditure and weight loss, while peripheral RAS suppressing resting metabolism and increasing weight gain.
A new study found that lifestyle factors such as obesity and smoking are associated with a worse quality of life rating for Acute Respiratory Distress Syndrome (ARDS) patients. The study suggests that incorporating smoking cessation education into the critical care setting may be beneficial in improving patient outcomes.
Severely obese patients undergoing weight loss surgery are at higher risk of fractures before and after surgery. The study suggests that guidelines should be followed on patient adherence to dietary supplements and physical activity to reduce fracture risk.
A recent study identified a genetic variant associated with higher BMI levels and increased efficiency of fat storage among Samoans. This 'thrifty' variant, found on chromosome 5, is linked to the islands' high obesity rates and may have evolved as an adaptation to food scarcity in ancient times.
A large study of nearly 21,000 people in Jilin Province found that being overweight or obese was associated with regular meat consumption, having ever been married, and getting less than 7 hours of sleep per night. The prevalence of obesity and overweight was higher among older adults, particularly those aged 55-64 and 65-79.
A recent study published in the journal Obesity found that severely obese women's brain activity differs from lean counterparts when it comes to responding to food cues. Despite reporting fullness, their brains continued to react similarly to hungry states, with sustained activation in reward centers.