Articles tagged with Obesity
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A new study published in Annals of Internal Medicine found that individuals with a maximum BMI in the overweight or obese categories had an elevated risk for all-cause death and deaths from cardiovascular disease, cancer, and respiratory disease. Participants who experienced significant weight loss were at the highest risk for death.
The partnership brings together the Endocrine Society's expertise and Medscape's innovative digital platforms to equip physicians with timely and useful guidance on diagnosing and treating endocrine disorders. Experts will produce original features and share case studies on Medscape Consult, leveraging its crowdsourcing platform.
Researchers found that cancer cells grew faster in fatty, obese tissue, suggesting the microenvironment surrounding cancer cells plays a crucial role in disease progression. Weight loss reversed changes to this microenvironment, correcting tumor growth, highlighting potential therapeutic targets for obesity-related cancers.
Scientists are shifting focus to combination therapies targeting multiple appetite control system components, driven by understanding of protein sensors and neurotransmitters. This approach aims to better regulate body's appetite, potentially leading to more effective obesity treatments.
Researchers at Joslin Diabetes Center identified a lipid molecule that signals brown fat cells to activate in mice, improving metabolism. The molecule, 12,13-diHOME, may also be used as a biomarker for brown fat activation in humans.
The patent analysis highlights the importance of saffron bioactives in treating multiple disorders, including neurological and metabolic conditions. Novel derivatives of safranal show promise in treating infectious diseases.
A new study reveals that there are over 79 rare genetic forms of obesity associated with various clinical features, far outnumbering previous estimates. The research highlights the need for national and international collaborations to identify the genes responsible for these syndromes.
A new study in the Journal of Consumer Research found that exposure to body cues can encourage overweight consumers to overspend. High-body-mass-index consumers were more likely to make indulgent spending decisions after seeing a thin shape.
Young men who are overweight or obese are at a higher risk of developing severe liver disease or liver cancer in later life. Men with obesity have more than twice the risk of liver problems compared to normal-weight men.
Research published in BMJ Open Diabetes Research & Care found that higher outdoor temperatures are associated with increased diabetes incidence and glucose intolerance prevalence worldwide. A 1°C rise in temperature could account for more than 100,000 new diabetes cases per year in the USA alone.
Researchers at The University of Manchester found that eosinophils, a type of immune cell, play a crucial role in maintaining healthy blood vessels by reducing artery contraction. In obesity, these cells are reduced, leading to impaired PVAT function and contributing to type 2 diabetes and hypertension.
Researchers found that whole body vibration reduced body fat, improved insulin resistance, and increased muscle and bone strength in a mouse model of morbid obesity and diabetes. Circulating osteocalcin levels also rose, indicating potential benefits for glucose regulation.
A new article explores how malnutrition and obesity are affecting obstetrical difficulties in women, leading to more difficult and dangerous births. The study highlights the importance of healthy nutrition in addressing this issue.
A study found that bariatric surgery prior to total hip or knee replacement can reduce in-hospital and 90-day postoperative complications, improving patient health for morbidly obese patients. However, it does not reduce the risk of needing a revision surgery.
Researchers have identified a specific genomic variant linked to obesity in West Africans and African-Americans, highlighting the importance of genomics research in diverse populations. The variant, found in approximately 1% of individuals, increases their risk of obesity by about six pounds.
A new study aims to identify factors that result in long-term diabetes remission and better blood sugar control after bariatric surgery. Researchers will follow up with approximately 242 patients over five years to analyze hormone secretion, metabolism, and complications.
New research reveals that overweight and obese people tend to live slightly shorter or similar lifespans compared to those with normal body weight. Lifetime risks for developing cardiovascular disease are higher in overweight and obese adults, with middle-aged women being 32% more likely to develop the condition.
Each succeeding generation shows a higher prevalence of arthritis, particularly among obese individuals. The study highlights the impact of obesity and concurrent lifestyle changes on arthritis rates over time.
Researchers at Columbia University Medical Center have discovered a bone-derived hormone that regulates food intake and blood sugar. The study found that the hormone, lipocalin 2, turns on brain neurons involved in appetite suppression, potentially leading to new targeted therapies for obesity and type 2 diabetes.
Research presented at the American Heart Association's Scientific Sessions found that playing Pokémon Go can increase daily steps by nearly 2,000 steps per day. Participants who were overweight or obese benefited most from the game, walking approximately 3,000 additional steps each day.
Researchers at Kanazawa University discovered that sulforaphane can lower body weight gain rates and reduce visceral fat. The compound also improves energy consumption and fat burning, likely due to its effects on the gut microbiome.
A large population study found that people who experience weight discrimination are less likely to be physically active. This is due to feelings of self-consciousness and negative stereotypes, leading to a lack of confidence to exercise in public.
A Penn study found that a high-fat diet causes epigenetic changes in fat cells, leading to obesity and type 2 diabetes. The research also identified a genetic defect in the Ucp1 gene that contributes to obesity, which can be overcome with treatment.
A study published in JAMA found that the percentage of overweight and obese adults trying to lose weight declined between 1988-1994 and 2009-2014. The decline was most pronounced among black women, who saw a significant reduction in reporting efforts to lose weight.
A recent study published at the American Heart Association's scientific sessions found that people are more likely to overeat in social settings. The research revealed that participants had a 60% risk of diet lapse when eating with others, and a 60% chance of overeating in restaurants.
A recent study by University of Kansas researchers found that people's political leanings and their own weight shape their opinions on obesity-related public policies. Republicans tend to believe eating habits cause obesity, while Democrats who identify as overweight are more likely to attribute the issue to genetics.
Researchers have identified 90 genes in fat cells that may contribute to obesity and cardiometabolic diseases. The study used a large dataset of Finnish men with detailed health records, revealing the effects of gene variations on human health and disease risk.
Scientists discovered that obesity disrupts the balance of 'guardian immune cells,' which maintain a delicate balance between immune systems. In healthy states, these cells protect against inflammation and metabolic disease, but in obese individuals, they lose their regulatory function.
Research published in the European Journal of Preventive Cardiology found that physical activity is associated with a lower risk of cardiovascular disease regardless of age. For middle-aged and elderly people, the benefits of physical activity may outweigh the impact of overweight and obesity on cardiovascular disease.
Researchers identified key strategies to enhance total knee replacement outcomes for patients with obesity, including managing chronic conditions and nutritional deficiencies. Excess soft tissue during surgery can obstruct visibility, leading to difficulty achieving proper alignment and implant fixation.
A large review found strong associations between obesity and risk of certain cancers, including oesophageal, bone marrow, colon, rectal, biliary tract system, pancreatic, endometrial, and kidney cancers. The study calls for more research to confirm these findings.
The AGA has created an Obesity Practice Guide to guide and personalize innovative obesity care for safe and effective weight management. The program includes a framework focused on business operational issues related to the management of obese patients, published in Clinical Gastroenterology and Hepatology.
Research reveals rosiglitazone treatment increases brown fat genes in mice, reversing genetic alterations associated with obesity. The findings suggest environmental changes can reverse some genetic defects linked to type 2 diabetes.
Research by UCL scientists found a strong association between long-term stress and obesity, with people experiencing chronically elevated cortisol levels being more prone to weight gain and persistent overweight status.
A large multiethnic study found that being underweight increases early death risk among postmenopausal women. Higher waist circumference, but not excess weight, is associated with premature mortality, highlighting the dangers of abdominal fat.
A new study analyzed 558 individuals with foot pain and identified five clusters with unique patterns based on age, sex, and comorbidities. The findings provide insights into foot pain patterns in the community and highlight opportunities for targeted interventions.
A three-year trial by the University of Liverpool found that liraglutide 3.0 mg reduces type 2 diabetes risk by 80% in individuals with obesity and prediabetes. Participants experienced greater sustained weight loss compared to a placebo.
A new study reveals that obesity reprograms muscle stem cells through DNA methylation changes, impairing insulin sensitivity and metabolism in fully developed muscle cells. The research, conducted by doctoral student Cajsa Davegårdh at Lund University, found that pro-inflammatory genes like IL-32 play a crucial role in this process.
A repurposed drug has been shown to prevent progression into diabetes in 80% of overweight patients with prediabetes, reversing the condition altogether in 60%. The study found that adding daily self-administered injections of liraglutide to diet and exercise significantly improved weight loss outcomes compared to placebo.
A study by Ohio State University researchers found that a Mediterranean diet rich in anti-inflammatory foods such as seafood and plant-based proteins can help reduce pain associated with obesity. The study also highlights the importance of diet quality over quantity in managing weight-related pain.
A University of Toronto study has identified a gene that may strongly influence obesity in humans, similar to the foraging gene found in fruit flies. The study reveals that the human version of this gene plays multiple roles in feeding and metabolism.
A long-term study found gastric band surgery improved patients' chances of diabetes remission, reduced medication needs and enhanced quality of life. The study also showed significant weight loss and low adverse events.
Researchers at Scripps Florida have identified a protein that promotes fat accumulation in animal models by slowing down energy breakdown. Deleting this protein's gene, IP6K1, has been shown to protect animals from both obesity and diabetes, regardless of diet or body temperature.
A recent study found that people who gained weight over their lifetime were more likely to develop esophageal and stomach cancers. The researchers analyzed data from over 400,000 people and discovered that those who became obese after a healthy weight had nearly tripled the risk of developing these cancers.
Research published in Experimental Physiology suggests that unsaturated fatty acids can reverse some of the effects of obesity on the immune system. Obesity was found to cause changes similar to those observed with aging, but supplementing the diet with unsaturated fatty acids reversed these effects.
Researchers have discovered a worm gene that triggers feelings of fullness and the need to sleep after eating, opening up potential for an obesity drug. The ETS-5 gene controls signals from the brain to the intestines, influencing food intake and activity.
A new report from Weill Cornell Medicine emphasizes the importance of evaluating medication side effects and interactions in obesity treatment. Physicians are advised to prescribe alternatives that limit weight gain or aid in weight loss for patients with obesity.
A new study found that 6% of low-income residents in Washington State lack reasonable access to healthy food due to a lack of personal vehicles. The researchers suggest expanding home delivery options and creating tools to assess food access reflecting local priorities.
A recent study published in the American Journal of Human Biology found that limited access to dietary protein is a potential driver of obesity among women of low socioeconomic status in Latin America. The researchers used the protein leverage hypothesis to understand differences in obesity among socioeconomic groups and discovered an ...
Researchers found that S6K1 phosphorylation mediates the transport of fatty acids, contributing to adiposity and aging. Mice with deficient EPRS showed similar physical characteristics to those with deficient S6K1, suggesting a dual role for S6K1 in obesity.
A mouse study found that prenatal BPA exposure weakens the body's fullness cues by reducing sensitivity to leptin, a hormone controlling appetite. This altered response can lead to increased obesity risk in offspring, supporting concerns about the potential impact of environmental endocrine disruptors on human health.
A Harvard study found that heavy lifting and non-daytime work schedules can decrease fertility in women, especially those who are overweight or over 37. The researchers measured biomarkers of fecundity in nearly 500 women seeking infertility treatment, revealing an inverse association between physical demands and egg yields.
Researchers found that online weight loss forums provide three types of responses: prospective, collective, and positive, which help users avoid shame and stigma. These supportive interactions encourage participants to remain anonymous and provide access to a tolerant community where everyone has something in common.
Researchers have cataloged 50 distinct cell types in a major appetite center of the brain, including two newly discovered subtypes that play a role in genetic control of obesity. The study provides a comprehensive parts list for this area of the brain, allowing researchers to identify which cells are responsible for specific functions.
A new study found that people with higher BMIs are less likely to receive hospice care, die at home, or receive high-quality end-of-life care. Those who did use hospice services spent fewer days in hospice due to differences in home hospice usage.
A study of provider-patient communication during weight-management visits found that quality benchmarks were not met, documented, or communicated in up to 42% of cases. The study highlights the need for improved communication and documentation to promote healthy lifestyle changes in overweight children.
A long-term study found that e-cigarette users who stopped smoking cigarettes substantially reduced their intake of cancer-causing chemicals compared to those who continued to smoke. The study confirms that e-cigarettes are much safer than conventional cigarettes and may be a useful long-term quitting aid for patients.
A new study by the National Institutes of Health found that couples with obesity take from 55-59% longer to conceive compared to their non-obese counterparts. The researchers calculated body mass index and found a significant decrease in fertility chances among obese individuals.
A new study from North Carolina State University highlights how people who have lost weight face 'lean stigma' and sabotage attempts from friends and family. Participants used communication strategies such as saving face and damage control to maintain their weight loss and relationships.
A recent review in Frontiers in Nutrition highlights the need for a more inclusive approach to obesity research, as traditional male rat models are found to be insufficient in predicting long-term obesity in females. The study also sheds light on the phenomenon of weight regain after weight loss and its impact on females.