Articles tagged with Obesity
A new study from UMass Medical School found that obese patients who underwent knee or hip replacement surgery reported similar pain relief and improved function as normal-weight patients. The study suggests that obesity is not a barrier to joint replacement surgery, which can provide long-term relief from joint pain.
A study published in JAMA Surgery found that women with certain risk factors, such as obesity and diabetes, may benefit from delayed breast reconstruction after mastectomy. This approach can help decrease the risk of serious wound complications compared to immediate reconstruction.
Researchers have discovered that adding estrogen to brain regions helps regulate weight and glucose levels in rats with induced menopause. The finding suggests that the medial amygdala is crucial for metabolic health, making it a potential target for treatment.
Researchers found a single amino-acid difference between toothed whales and filter-feeding baleen whales that may explain their distinct body shapes. This variation affects the sensitivity of a key receptor, potentially impacting feeding behavior and body size in these species.
Researchers found that obese people tend to ignore future meal timings when selecting portion sizes, unlike lean individuals who generally do. This novel finding highlights the need for targeted interventions to promote future thinking in meal planning and may explain why being overweight is associated with irregular meal timings.
A systematic review of 37 studies found a link between artificial sweetener consumption and higher risks of weight gain, obesity, high blood pressure, diabetes, and heart disease. The evidence suggests that artificial sweeteners may have negative effects on metabolism and gut bacteria, although the evidence is conflicting.
Men who are tall and obese have an increased risk of high grade prostate cancer and death from prostate cancer, according to a study published in BMC Medicine. The research found that height is not associated with overall prostate cancer risk but increases the risk of high grade disease and death by 21% and 17% respectively.
A Wayne State University researcher is leading a clinical research study to develop a better understanding of type 2 diabetes in obesity and improve therapy for veterans and others with the disease. The study aims to characterize a cohort of obese people with and without Type 2 diabetes to distinguish different genetic subtypes.
The USPSTF found a small but positive benefit of behavioral counseling for cardiovascular disease prevention in adults without obesity who do not have high blood pressure, abnormal cholesterol or blood sugar levels or diabetes. Behavioral counseling interventions improve healthful behaviors and reduce CVD risk factors, with minimal harms.
A randomized clinical trial investigated whether allowing infants to self-feed solid foods reduces the risk of overweight. The study found that a baby-led approach did not improve energy self-regulation or body weight but showed benefits in attitudes towards food.
The study analyzed data from 717,000 people in 111 countries and found that big gaps between activity levels coincided with higher obesity rates. The research also highlighted the powerful role of gender in country-to-country differences, with women affected more dramatically by negative consequences.
A large-scale study of daily step data from anonymous smartphone users in over 100 countries reveals how countries, genders, and community types fare in terms of physical activity. The study found that countries with greater activity variation have a larger proportion of inactive women and higher obesity rates.
A study found that age and obesity create a perfect storm that damages the tiny blood vessels that directly feed the heart muscle, leading to reduced blood flow and increased risk of heart failure. The inflammation caused by both factors thickens the walls of these microvasculature, making them less able to dilate and sustain the heart.
A randomized clinical trial found that mindfulness-based stress reduction (MBSR) decreased stress and improved blood sugar levels in overweight women. While MBSR had no significant impact on weight or insulin resistance, it may have potential benefits for the prevention and treatment of diabetes.
A 16-year study found that men who never smoked, maintained a healthy diet, and weren
A recent study published in Cell Metabolism found that brain-resident immune cells called microglia play a crucial role in driving overeating and weight gain in mice fed high-fat diets. The study suggests that targeting microglia could provide a novel approach to treating obesity, potentially avoiding side effects of existing medications.
Researchers discovered that blocking a specific intestinal microbial pathway can prevent obesity, insulin resistance, and promote active fat tissue. High levels of TMAO are linked to Type 2 diabetes and cardiovascular disease.
Researchers found that overweight or mildly obese individuals have better survival rates after a stroke compared to those with normal body weight. The study suggests that increased weight may provide a 'metabolic reserve' that helps recovery from severe disease.
A new study suggests that genetic predisposition to type 1 inflammation protects against NAFLD, but type 2 inflammation actually worsens the condition. Targeted treatments for metabolic syndrome may need reevaluation due to this unexpected finding.
A Swedish study published in Neurology found that teenage weight gain is associated with a higher risk of stroke in adulthood. The study followed 37,669 men and found that those who experienced a significant increase in BMI from childhood to age 20 were more likely to develop high blood pressure and stroke.
A study by UT Southwestern Medical Center found that mildly obese patients who survive a major heart attack tend to have better outcomes, including higher survival rates and shorter hospital stays. Patients considered mildly obese had a 30% increased likelihood of survival compared to those of normal weight.
Researchers at the University of Iowa found that mildly stressing muscle metabolism boosts levels of fibroblast growth factor-21 (FGF21), a beneficial hormone that prevents obesity and diabetes in mice. FGF21 production reversed conditions and returned mice to normal weight and blood sugar levels.
A National Institutes of Health-funded study found that moderate-intensity exercise reduced the risk of major mobility disability by 31% in older adults with extreme obesity. The structured physical activity program improved participants' ability to perform common daily activities, such as walking a block around the neighborhood.
The Endocrine Society issued a Scientific Statement on obesity's causes, emphasizing the need to understand underlying mechanisms that make it difficult to maintain weight loss. The statement highlights the complex interplay between genetics, developmental influences, and the environment in contributing to obesity.
Despite being hailed as the key regulator of leanness, leptin's function in humans remains uncharacterized. Researchers call for experimental evidence to demonstrate its mechanism of action, highlighting a crucial gap in our understanding of metabolism and obesity.
Women who received specialist care were eight times less likely to have a stillbirth. The clinic helps spot signs of complications sooner and provides tailored advice on healthy eating and weight management during pregnancy.
A new reconstruction method for Electrical Impedance Tomography (EIT) is proposed to estimate abdominal fat, improving reproducibility and spatial resolution. The technique has shown promising results in detecting subcutaneous fat thickness, with further research needed to assess visceral fat volume.
A University of Alberta research team found that patients with obesity have a higher risk of infection within 30 days after heart bypass surgery, and 88% of these patients received non-surgical PCI. This increased risk may be due to the fact that patients with obesity are more likely to receive PCI.
A new study published in Cellular and Molecular Gastroenterology and Hepatology found that consuming unsaturated fat can lead to fatty liver disease, contrary to its previously touted health benefits. The research used mice fed diets supplemented with either saturated or unsaturated fat, revealing the latter can cause liver damage.
Researchers from the University of Pennsylvania School of Medicine discovered a molecular player that acts as a pilot light to turn on brown fat, which burns sugar and fat to produce radiant heat. Mice lacking this molecule, histone deacetylase 3 (HDAC3), are unable to activate brown fat, highlighting its crucial role in metabolism.
A population study found that being overweight or obese, as defined by body mass index, abdominal obesity, and higher body fat percentage, is associated with a higher risk of developing rheumatoid arthritis in women. In contrast, no clear association was found between RA risk and BMI criteria for men.
A study published in Obesity Surgery found that only 2,112 out of 37,806 patients (5.58%) underwent subsequent body contouring procedures after bariatric surgery. The majority of these patients had higher incomes or health insurance, and the procedures usually occurred within two years after the initial bariatric procedure.
A new USC study found that a poor diet, combined with the ApoE4 gene variant, can increase the development of Alzheimer's plaques in mice. The study suggests that lifestyle factors such as diet and exercise may play a role in regulating the risk of Alzheimer's disease.
A new University of Iowa study examines the link between obesity and food container chemical substitutes, finding no associations with BPF and BPS. However, the study confirms that BPA is associated with increased obesity in humans.
Among older patients with diabetes, being overweight reduces the risk of early death by 18% compared to normal weight counterparts. However, this survival benefit is only observed in older patients and diminishes over time.
A new study published in Social Science and Medicine found that a rewards programme increased weight loss magnitude and duration by more than twice as much as a control group. The programme, which offered cash or lottery tickets for meeting monthly weight loss goals, also led to higher rates of sustained weight loss.
A study found that obese patients undergoing shoulder joint replacement surgery are at increased risk of complications, including the need for revision surgery and postoperative infections. The risk of revision surgery increases steadily with increasing body mass index (BMI) in obese patients.
Researchers found that vaccinated obese adults are twice as likely to develop influenza and flu-like illnesses compared to those of healthy weight. The study suggests that existing blood tests may provide misleading information for obese individuals.
A new guide from Tulane University aims to address inherent sex bias in pre-clinical research on metabolic diseases. The guide emphasizes the need to consider sex differences in biological mechanisms, not just hormones, to accelerate discovery and treatment.
Researchers found that small and very small unruptured intracranial aneurysms have low growth rates, ranging from less than 3% per year. The annual rupture rate for aneurysms smaller than 7mm was 0-1%. These findings may inform patient management and treatment decisions for patients with UIAs.
Researchers found that a diabetes medication, linagliptin, can protect against stiffening of the left ventricle of the heart in overweight female mice fed a Western diet. The treatment suppressed oxidative stress, inflammation, and fibrosis, reducing the risk of cardiovascular complications associated with obesity and Type 2 diabetes.
Research on mango consumption found potential benefits for metabolic disorders and inflammation, with improved blood pressure and gut health observed in human studies. The superfruit's galloyl derivatives showed anti-inflammatory activities and altered the gut microbiota and metabolism in lean and obese subjects.
Researchers found that higher body mass index (BMI) can cause worse cardiovascular health in young adults as young as 17, according to a study using data from the Avon Longitudinal Study of Parents and Children. The study suggests that tackling obesity from an early age may help prevent cardiovascular changes that are precursors to car...
A new study published in Current Developments in Nutrition found that lean pork as part of a weight-loss diet can lead to significant weight loss, improved physical function, and better adherence to the diet among obese women. Both groups experienced improvements in functional capacity at six months, with African American women experie...
A recent study found that nearly 1 in 5 patients with lap-band surgery undergo multiple device-related reoperations, and complication rates range greatly. Accredited bariatric centers also vary significantly in their rates of serious complications, with a 17-fold difference between the highest and lowest rates.
Researchers found that capsaicin in red chili prevents microbial dysbiosis and gut barrier dysfunction, leading to reduced inflammation and obesity. The study suggests that the gut microbiome plays a critical role in the anti-obesity effects of capsaicin.
Research suggests overweight boys may be at increased risk of colon cancer as adults if they remain overweight. However, those who lose weight and achieve a healthy BMI by young adulthood appear to have similar risk profiles. The study highlights the importance of maintaining a healthy weight in childhood.
A new study suggests using a mindfulness approach can aid in weight loss by increasing mindful eating and reducing energy intake, leading to significant weight loss results. The study found that participants who completed the Eat Smart, Move More, Weigh Less program lost more weight than those in the waitlist control group.
The report assesses current cancer risk factors and prevention measures, highlighting improvements in some areas but stagnation or decline in others. Cigarette smoking among adults has dropped to 15% but remains high in certain geographic areas, while obesity prevalence continues to rise, particularly among black women.
A study of over 16,000 healthy adults found that those who followed a pro-vegetarian diet had a significantly lower risk of developing obesity. The researchers found that participants with the most vegetarian diet had a 43% reduced risk of obesity compared to those with the least vegetarian diet.
A Cornell University study found that white women are penalized for being overweight, while white men face penalties for both underweight and overweight status. In contrast, African Americans have become more accepting of larger bodies.
A study published at European Congress on Obesity found that people with higher levels of visceral fat (internal fat around organs) and thigh muscle fat spend more nights in hospital. Visceral fat was significantly associated with healthcare burden, while thigh muscle fat infiltration had mixed results.
A new research study presented at the European Congress on Obesity suggests using a mindfulness approach is an effective way to aid weight loss. Participants who completed the online program 'Eat Smart, Move More, Weigh Less' lost more weight than those in the waitlist control group.
A study tracking body mass index over 16 years found that women who are divorced, separated, or widowed and smokers are at high risk of becoming overweight or obese. Measuring rates of weight gain between 18-23 years old could help identify those who need assistance with prevention.
Replacing one serving of sugar-sweetened soft drink or beer with a glass of water daily can lower the incidence of obesity. Drinking water instead of beer was found to reduce obesity risk by 20%, while substituting other sugary drinks showed no significant effect.
A recent study of 160 participants found that being overweight or obese increases the likelihood of having poor oral health. Patients with obesity were almost 6-times more likely to have severe periodontitis compared to normal-weight individuals.
Research reveals survivin protein protects fat cells from death in obese individuals, potentially leading to new obesity and cancer treatments. The study found higher levels of survivin in obese subjects, suggesting it could be a target for therapy.
A new swallowable gastric balloon, Elipse Balloon, has been shown to be safe and effective for inducing substantial weight loss in obese individuals. The study found a mean weight loss of 15.2 kg after 16 weeks, with significant reductions also observed in comorbidities such as diabetes and high blood pressure.
A study of 3.5 million people found that 'metabolically healthy' obese individuals have a higher risk of cardiovascular disease events, including heart failure and stroke, compared to normal-weight individuals with no metabolic abnormalities. The study also showed that the risk of CVD events increases with the number of metabolic abnor...
A new study published at the European Congress on Obesity found that regular physical activity and avoiding inactivity significantly reduce the build-up of dangerous liver fat. The researchers discovered that moving about more throughout the day, such as breaking up long periods of sitting, is a key factor in maintaining metabolic health.