Articles tagged with Obesity
A recent study led by York University researchers found that individuals with severe obesity who are fit have a similar health profile to those who weigh significantly less. Regular exercise can lead to dramatic improvements in health for those with severe obesity, even if they don't lose weight.
A recent study found that nearly 60% of cases studied had combinations of obesity, hypertension, high cholesterol, diabetes, and smoking. Researchers suggest extending prevention efforts to routine preventive visits for children and young adults to reduce adult cardiovascular disease.
Research finds obese male patients treated with targeted or immune therapies live significantly longer than those with a normal BMI. The 'Obesity Paradox' suggests that obesity may improve survival in men with metastatic melanoma, contradicting prior assumptions about the impact of weight on cancer outcomes.
A new study shows that a plant-based diet improves beta-cell function and insulin sensitivity in overweight adults without a history of diabetes. Participants who followed a low-fat vegan diet experienced increased meal-stimulated insulin secretion and decreased blood sugar levels.
Scientists discover two new feedback loops that regulate energy expenditure, with TBK1 inhibiting AMPK's role in burning fat. Deleting TBK1 from fat cells increases inflammation and weight loss.
The prevalence of obesity in the US has risen dramatically, but its economic impact on individual states is less understood. A recent study found that health care costs devoted to treating obesity-related illness vary significantly across states, with some spending over 12 percent of their total medical expenditures on obesity treatment.
A study found that obese men have higher levels of inflammatory markers in their seminal fluid and lower sperm quality, correlating with body mass index (BMI). Chronic inflammation in the male reproductive organs may explain the link between obesity and reduced fertility.
A new study from Karolinska Institutet shows that exercise training enhances fat metabolism and strengthens the anti-inflammatory properties of the immune system. Daily doses of kynurenic acid activated cell receptor GPR35, converting white fat to energy-burning brown fat.
Dr. Alexis M. Stranahan's study suggests that an apple-shaped physique, characterized by fat depositing around the abdominal cavity, may be worse for the brain than previously thought. Conversely, subcutaneous fat under the skin appears to protect the brain from cognitive decline.
A large retrospective study found that obese men and those with metabolic syndrome had a higher risk of biochemical recurrence after radical prostatectomy. Patients with obesity had a 32% higher chance of recurrence compared to those with normal weight, while those with metabolic syndrome had over four-fold increased risk.
Reducing Canada's overweight and obese population by 50% could prevent up to 59,829 cancer cases by 2042. Effective interventions could lower cancer incidence by projecting the impact of population-level changes on cancer rates.
A recent study by Penn State researchers found that training individuals in portion-control strategies can lead to healthier food choices and reduced overall calorie intake. The study showed that even when given larger portions, participants who received training chose lower-calorie-dense foods and consumed fewer calories.
A new study from the University of Illinois explains what it takes to get a cat to slim down, targeting a safe level of weight loss and maintaining lean mass. The researchers found that reducing food intake by 20% compared to a maintenance diet was necessary to achieve this goal.
The Office of Dietary Supplements at NIH has released two new resources to help people understand the effectiveness and safety of dietary supplements promoted for fitness and weight loss. The fact sheets cover over 20 ingredients found in these products, including antioxidants, creatine, and protein.
A study led by Georgia State University found that dietary fiber inulin prevented metabolic syndrome by restoring gut microbiota levels, increasing intestinal epithelial cell production, and regulating interleukin-22 expression. This study suggests that fermentable fibers like inulin may promote better health by suppressing obesity and...
Researchers from the University of Basel found that gastric bypass and sleeve gastrectomy surgeries result in similar weight loss outcomes, with patients losing two-thirds of excess weight. Additionally, gastric bypass showed better results in reducing symptoms of gastric acid reflux.
Research reveals that evening hours are a high-risk time for overeating, particularly among individuals prone to binge eating. The study found that stress levels spike in the evening, increasing hunger hormone ghrelin and decreasing satiety hormone peptide YY.
Obese adults with type 2 diabetes who underwent gastric bypass surgery showed improved blood sugar control, cholesterol management, and reduced blood pressure after five years. However, the improvement in achieving these targets diminished over time, suggesting that longer follow-up is needed to understand the persistent benefits of we...
A retrospective cohort study found that bariatric surgery is associated with a lower risk of death from any cause compared to nonsurgical obesity management. The study analyzed data from over 8,000 patients who underwent weight-loss surgery and 25,000 who received nonsurgical care.
A study published in JAMA found that bariatric surgery prolongs lifespan in obese individuals, with a 50% lower death rate compared to traditional medical treatment. The study tracked 33,540 obese individuals for up to 10 years and revealed that women have the majority of bariatric surgery.
Rising US obesity has been linked to exceptionally slow mortality rate improvements and increased life expectancy gaps with other wealthy countries. The study found that a 0.54% reduction in annual death rate gains was associated with the rise in maximum lifetime body mass index.
A new study found that risk of diabetes is double for black patients, with strongest rising risk trends seen among whites. Obesity prevalence was highest among black women, while socioeconomic status and physical activity levels also played a significant role in diabetes development.
A study published in The BMJ found that improving diet quality leads to greater weight loss in people with a high genetic risk of obesity. The research analyzed data from two large studies and found that adhering to healthy dietary patterns can attenuate the genetic association with weight gain.
New research uses 3D imaging to visualize the inner workings of fat tissue in mice, identifying potential targets for new drugs to treat and prevent obesity and diabetes. The study reveals that beige fat, which can be induced to burn energy, has high potential for treatment.
Researchers have identified a specific gene, ADCY3, that predisposes Greenlanders to obesity and diabetes when it is inactive. The study, published in Nature Genetics, found that 4.4% of test subjects had the gene inactive, leading to significant weight gain and increased risk of diabetes.
Researchers at UCSF have discovered that primary cilia on brain cells play a crucial role in signaling appetite control. Mutations in the MC4R gene, found in nearly all cases of severe obesity, are linked to impaired communication between neurons via primary cilia.
Researchers at UTMB discovered a molecule that blocks the metabolic brake in obese white fat cells, increasing metabolism and reducing fat tissue mass. The drug-treated mice lost over 7% of their body weight and had lower blood cholesterol levels compared to placebo group, without suppressing appetite.
Experts argue that sugar may play a key role in obesity and type 2 diabetes due to its unique metabolic effects, potentially beyond just excess calories. The World Health Organization describes the twin epidemics as a 'slow-motion disaster,' but critics say current recommendations targeting only calories are insufficient.
A new Northwestern Medicine study finds that blacks have the same risk of developing diabetes as whites when all biological factors are considered over time. Obesity is identified as the primary cause of early onset diabetes in blacks, with black women developing diabetes at triple the rate of white women.
New research suggests that a diet low in branched-chain amino acids (BCAAs) may improve metabolic health and promote leanness. The study found that obese mice on a specialized diet experienced improved glucose metabolism and energy expenditure despite not reducing overall calorie intake.
Researchers at WashU Medicine identified a way to prevent fat cells from growing larger, leading to weight gain and obesity. By activating a specific protein pathway in mice, they found that high-fat diets did not lead to obesity.
A smartphone app, SlipBuddy, uses machine learning to uncover patterns and predict eating trouble spots, providing interventions and helping change behavior. The app showed positive results in a pilot study, with nine participants losing an average of five pounds.
A study published in The Lancet Public Health found that people living within a kilometre of physical activity facilities have smaller waist circumferences, lower BMI, and lower body fat percentages. Increasing access to physical activity facilities and reducing fast food outlets may help reduce obesity.
A new study by NYU College of Global Public Health and the University of Michigan found no evidence of an 'obesity paradox' among people with new cases of cardiovascular disease. This contradicts prior research that suggested obesity may be associated with improved survival in people with existing cardiovascular disease. The study used...
Researchers at McMaster University have identified nine genes that contribute to weight gain in individuals with a high body mass index. These genes can amplify weight gain by up to four times, making them a significant factor in the development of extreme forms of obesity.
A study published in Obesity found that individuals with Type 2 diabetes and obesity who continue to binge eat while trying to lose weight drop significantly less weight than those who don't or stop binge eating. Researchers recommend targeting treatment for this behavior, such as cognitive behavioral therapy.
Two studies in mice and human subjects reveal exercise can alter gut microbiota, promoting healthy intestinal cells and reducing inflammation. Exercise-induced changes persisted even after returning to a sedentary lifestyle, with lean participants showing more significant improvements.
Research indicates that being overweight or obese can lead to poorer RA treatment outcomes and higher mortality risk. Studies show that patients with healthy weights are more likely to achieve remission, while those who are overweight or obese face a 25-47% lower chance of sustained remission despite similar treatments.
A global longitudinal study confirmed that people with high body mass index (BMI) are more likely to develop dementia than those with normal weight. The study analyzed data from over 1.3 million adults in the US and Europe, finding that individuals near dementia onset tend to have lower body weight.
A new study found that fat distribution patterns, not just overall weight, are linked to heart attack risk in women and men. Women had higher subcutaneous fat but lower lean mass compared to men, who had more visceral adipose tissue and ectopic fat.
A new study published in The Lancet Diabetes & Endocrinology found that diabetes and being overweight or obese are responsible for nearly 800,000 new cancer cases globally. High BMI was linked to twice as many cancers as diabetes, with liver cancer and endometrial cancer being the most common types.
A new study found that weight loss through diet and exercise significantly slows down the degeneration of knee cartilage in obese individuals. However, weight loss achieved solely through exercise had no significant impact on cartilage degeneration, suggesting that a balanced approach involving diet is crucial for protecting the knees.
Researchers from UNIGE have identified a key role for the liver in the development of type 2 diabetes, linked to obesity and inflammation. By targeting the protein PTPR-γ, scientists may uncover new therapeutic strategies to prevent insulin resistance and related metabolic conditions.
The study reveals huge inequalities persist with heart disease accounting for over 50% of all deaths in many middle income countries, compared to less than 30% in high income countries. The UK has the highest prevalence of adult obesity in males and 2nd highest in females, and ranks joint 5th for raised blood cholesterol.
New research reveals cinnamaldehyde's ability to induce thermogenesis in fat cells, improving metabolic health. The compound may offer a non-pharmacological approach to combating obesity and related health issues.
A new test predicts which people with type 2 diabetes will benefit from weight loss surgery. The DiaBetter score and percentage weight loss two years post-surgery are key predictors of T2D remission.
Scientists at University of Basel find feedback mechanism to maintain insulin production in overweight patients, using ILC2 immune cells and retinoic acid. The study highlights the complex interactions between endocrine and immune cells in regulating insulin release.
A study found that women who underwent sleeve gastrectomy may need to limit their alcohol consumption due to faster absorption rates. The surgery speeds up the transfer of alcohol into the bloodstream, leading to higher blood alcohol levels and increased risk of binge drinking and associated health issues.
Researchers have identified a three-molecule signature that accurately indicates insulin resistance, or pre-diabetes, in mice. This discovery could enable earlier detection of pre-diabetes in humans and tailor healthcare treatments to individual patients' needs.
A recent Drexel University study discovered that when vegetables and dairy products are pricier than unhealthy snacks like chips, people's dietary quality suffers significantly. The researchers found a strong link between the price gap and lower odds of having a healthy diet, particularly among middle-income groups.
A study published in The BMJ found that weight-reducing diets, mostly low in fat, may decrease all-cause early death in adults with obesity. This supports the implementation of public health measures to prevent weight gain and promote weight loss. However, the evidence for reducing heart disease and cancer deaths is limited.
A genetic variant in ankyrin-B gene causes cells to store more fat, leading to obesity. This variant is carried by millions of Americans and can be identified through family history and physiological traits.
Women with anorexia nervosa and obesity have lower levels of allopregnanolone, a key player in regulating mood, compared to normal-weight women. Low allo levels are associated with greater severity of depression symptoms, suggesting a potential new target for treating these disorders.
Research suggests that obese older adults who undergo cardiac surgery may experience greater functional decline over two years. The study analyzed data from 1,731 participants and found a complex relationship between obesity and functional ability in those aged 80 and older.
A recent study has identified Neuregulin 4 (Nrg4) as a key driver of nonalcoholic steatohepatitis (NASH) progression. Increasing levels of Nrg4 protected liver cells from metabolic stress in mice, while loss of the hormone led to accelerated disease progression.
A comprehensive study reveals that displaying calories on menus reduces consumer calorie intake by 27 calories per meal, while retailers respond by offering more low-calorie options.
A new study found that phenylalanine reduces food intake by affecting the gut and brain, suggesting it may be used to treat or prevent obesity. The amino acid suppressed appetite by releasing hormones in the gut and activating areas of the brain involved in appetite regulation.
The prevalence of obesity in the UK has almost doubled over two decades, with food taxes being suggested as a measure to correct this trend. However, experts disagree on its effectiveness, with some arguing it is too simplistic and overlooks other factors influencing obesity.
Research suggests that obesity is prevalent among axSpa patients, associated with increased disease activity, physical function impairment, and poorer quality of life. The study found that nearly two-thirds of the patient cohort were overweight or obese, highlighting the need for weight management strategies in treatment plans.
Research findings from the ACR/ARHP Annual Meeting reveal that obesity is independently associated with worse patient-reported outcomes in women with systemic lupus erythematosus, including increased disease activity and depressive symptoms. Obesity was linked to higher levels of pain and fatigue as well.