Articles tagged with Obesity
A fecal transplant from a lean donor can temporarily improve insulin resistance in obese men, but only half of the recipients responded. The success of the treatment depends on each patient's fecal gut-bacterial makeup, which can be predicted through analysis.
Researchers compared GM soybean oil to conventional soybean, coconut, and olive oils, finding that GM soybean oil reduces obesity and insulin resistance but causes similar negative effects on diabetes and fatty liver as conventional soybean oil. Olive oil produced identical negative effects to Plenish.
Scientists at NGM Bio have uncovered the molecular biology and mechanisms of Growth and Differentiation Factor 15 (GDF15), a hormone regulating body weight. The study reveals potential therapeutics for diseases of excess and insufficient body weight, including obesity and cachexia.
Midlife women experience significant weight gain, mainly in the midsection, increasing cardiovascular disease risk. Researchers recommend primary care providers screen for overweight and establish behavioral interventions, including psychological support and physical activity.
Scientists at the University of Warwick have identified tanycytes, key brain cells controlling appetite, which detect amino acids in food and inform the brain about fullness. Eating foods high in specific amino acids can activate these cells, leading to feelings of fullness and potentially aiding weight management.
Researchers found that a diet rich in saturated fats damages the brain's hunger control system within days, while gut bacteria changes occur weeks later. The study suggests that this sequence of events may contribute to weight gain and obesity.
A new study suggests that weight loss in adults leads to significant cost savings, peaking at age 50. The research found that an adult who goes from obese to overweight can save $17,655 in direct medical costs and productivity losses over their lifetime, while losing weight from obese to healthy results in a savings of $28,020.
A study from the University of Pennsylvania School of Nursing highlights the challenges of transitioning severely obese patients to nursing homes after acute care stays. The researchers found that patient size and bariatric equipment availability can act as barriers, leading to poor outcomes and increased costs.
A study found that Mexican-Americans living in the US have more risk factors for liver cancer, including obesity and diabetes, compared to those in Mexico. The study's lead author notes that having multiple risk factors increases the likelihood of developing liver cancer.
A new method targets the appetite-stimulating hormone ghrelin to prevent post-diet weight gain in mice. Mice treated with a virus expressing butyrylcholinesterase (BChE) gene therapy showed reduced weight regain and improved glucose tolerance after switching back to an unrestricted diet.
A SISSA study finds that people of normal weight associate natural foods with their sensory characteristics, while overweight individuals link processed foods to context. The research also highlights differences in brain activity between underweight and overweight participants when consuming the same stimuli.
A recent international multi-centre weight study found that overweight dogs can lose up to 11% of their bodyweight through specially-formulated diets. The study, published in PLOS ONE, also revealed improvements in activity and quality of life among dog owners.
A recent study published in Andrologia reveals that obesity is associated with lower semen volume, sperm count, and motility. The findings suggest that weight loss before conception may improve fertility outcomes for couples seeking infertility treatment.
Researchers at WashU Medicine have identified a way to convert white fat into beige fat, a type of fat that burns calories and protects against obesity. By blocking a specific protein in white fat cells, scientists can induce the production of beige fat, leading to weight loss and improved metabolic health.
A study published in JAMA found that a postoperative 48-hour course of antibiotics significantly decreased the rate of surgical site infections within 30 days after delivery among obese women. The researchers used oral cephalexin and metronidazole, and found a 10.9% overall SSI rate compared to 15.4% in the placebo group.
University of Tasmania researchers found that taking a 2-week break during dieting can lead to greater weight loss and less weight regain. The study showed participants who alternated between dieting and regular eating for 30 weeks lost an average of 8 kg more than those who continued with continuous dieting.
A Chinese study found that women with visceral fat (around internal organs) are at higher risk for developing ER- breast cancer, while those with subcutaneous fat are more likely to develop ER+ breast cancer. The study's findings suggest a complex link between breast cancer and obesity.
Researchers found that a weight loss of more than 10% can lead to a significant reduction in disease risk for individuals with metabolically unhealthy obesity. This intermediate goal can serve as a low-hanging fruit, providing documented protection against obesity-related metabolic diseases, and improving patient motivation through doc...
New research suggests that eating six meals per day improves blood sugar control and reduces hunger in obese individuals with impaired glucose tolerance or type 2 diabetes. The study found that the six-meal plan decreased glycated haemoglobin levels, post-oral glucose tolerance test blood glucose levels, and abnormally high insulin lev...
A recent study published in Diabetologia found that weight loss after obesity surgery can reverse early eye damage caused by obesity, high blood pressure, and diabetes. The research team discovered improvements in the retinal microvasculature of obese subjects following bariatric surgery.
A new study from the University of Copenhagen found that a specific ratio of gut bacteria can predict weight loss success on a high-fruit diet. Approximately 50% of the population has this beneficial bacterial balance, which can help tailor nutritional advice for individual weight loss needs.
The Lancet's analysis shows that while some countries have made significant improvements, much progress is needed to meet the health-related SDG targets by 2030. Over 60% of countries are projected to meet targets on under-5 mortality, neonatal mortality, maternal mortality, and malaria.
A new study published in International Journal of Obesity suggests that the effectiveness of high-fiber diets depends on the type of bacteria in a person's intestine. The research found that participants with a specific combination of Prevotella and Bacteroides bacteria lost more weight and body fat when following a high-fiber diet.
A new non-surgical device has shown promising results as an NHS treatment for people with type 2 diabetes and obesity. After one year, participants lost significant weight, had improved blood sugar control and reduced systolic blood pressure, with high patient satisfaction levels.
A new study published in Diabetologia found that cognitive behavioral group therapy (CBGT) is no better than standard care at preventing weight regain after dieting in people with type 2 diabetes. CBGT aimed to change thought patterns and behaviors, but failed to improve cardiovascular risk factors or psychological wellbeing.
Studies suggest having an obese spouse substantially increases a man's risk of developing type 2 diabetes, while women with an obese partner are not at increased risk. The research highlights the importance of screening spouses for diabetes if obesity is found in one person.
A large study found that metabolically healthy obese individuals have a higher risk of coronary heart disease, cerebrovascular disease, and heart failure compared to normal weight individuals with no metabolic abnormalities. Underweight individuals also face increased risks for certain cardiovascular diseases.
A new method of analyzing subcutaneous fat has been developed to predict which patients will respond well to obesity surgery. The FAT score technique showed a significant association between a patient's fat score and their response to surgery, with severely obese patients having an increased risk of poor weight loss response.
A large study found that individuals with 'metabolically healthy obese' (MHO) have a higher risk of cardiovascular disease events, including coronary heart disease and strokes. This contradicts the notion that MHO is harmless and highlights the importance of weight loss for all obese individuals.
A new study from Uppsala University finds that genetic effects on obesity are not fixed but interact with lifestyle factors. The study reveals that physical activity and socio-economic status can reduce the impact of genes on weight.
Research suggests that mangos and their components have anti-inflammatory and anti-oxidative properties, which may help reduce risk for chronic disease. Mangos are also associated with better nutrient intake, glycemic control, and improved gut health.
A community-based study of 5248 older adults found that a healthy lifestyle can compress the disabled period by improving walking distances and diet quality. Obesity was associated with an expanded disabled period, while smoking shortened life and able life.
Researchers discovered that a particular receptor in kidney cells plays a crucial role in obesity-induced kidney damage. Targeting this receptor or its associated signaling pathway may help protect the kidneys of individuals with obesity from structural and functional changes, thereby reducing the risk of chronic kidney disease.
Researchers at LSU Health New Orleans have discovered the potential of a protein called Nischarin to treat or prevent metabolic diseases such as obesity and diabetes. The findings showed that Nischarin interacts with and controls the activity of a gene called AMPK, leading to improved glucose and insulin tolerance.
A recent CARBS study showed that salacia extract reduces appetite and manages blood sugar levels by improving glycemic indices and gut hormones in healthy overweight/obese individuals. The proprietary extract, OmniLean, also reduces spikes in blood sugar and hunger pangs.
A new study suggests that metabolically healthy obese adults consuming a diet high in unsaturated fats may be able to decrease their total cholesterol by 10 points. However, replacing saturated fats with unsaturated fats does not aid in weight loss.
Researchers found that obese people have fewer enteroendocrine cells in the gut, reducing satiety hormones and altering appetite. Surgical weight-loss procedures can repair this disorder by restoring cell numbers and normalizing hormone release.
A study of 183 participants found that those who lost a consistent number of pounds each week had better weight loss outcomes than those with high weight variability. This suggests that developing stable behaviors related to food intake and weight loss is crucial for maintaining changes in the long term.
Underweight patients undergoing cardiac catheterisation are more likely to die, experience longer hospital stays, and incur higher costs compared to normal weight or obese patients. Morbidly obese patients, on the other hand, have better outcomes despite having a lower BMI.
A study published in Science Signaling reveals that enhanced natriuretic peptide signaling in adipose tissue protects against obesity and insulin resistance. Boosting levels of NPs in adipose tissue may be an important avenue for combating metabolic disease.
Studies on red raspberries found that consuming the fruit may improve glucose control and reduce hunger. Researchers also discovered that red raspberry consumption can alter gut microbiota and show promise in reducing inflammation and obesity risk.
Researchers found that increasing BMP4 levels can improve metabolic health in lean mice by promoting beige fat cell activity, but overweight mice showed reduced effectiveness. Gene therapy with BMP4 also protected against insulin resistance in both lean and overweight mice.
Researchers at the University of Birmingham have discovered that GLP-1 agonist extendin-4 significantly reduces brain pressure in an animal model, with effects lasting at least 24 hours. The treatment shows promise as a novel new way to lower brain pressure, potentially benefiting patients with conditions such as traumatic brain injury...
A study using fMRI scans found that reduced neural activity in teens at high risk of adult obesity may be an early predictor. The researchers discovered that lean adolescents with a family history of overweight parents showed less self-regulation activity than their peers.
Research reveals NPGL, a newly discovered protein involved in brain signalling, controls appetite and increases body fat storage even on low-calorie diets. The study also shows NPGL's role in increasing food intake when high caloric foods are consumed.
Researchers found that being overweight or obese increases a person's risk of coronary heart disease by up to 28% even if they have healthy blood pressure, blood sugar, and cholesterol levels. The study showed that excess weight is linked with an increased risk of heart disease, even when people have a healthy metabolic profile.
A study published in Hormones & Cancer found that obese rats with sensitive androgen receptors had more aggressive tumors, even after anti-estrogen treatment. Researchers identified inflammation and cytokine interleukin 6 as key factors contributing to this sensitivity, highlighting the potential for personalized therapeutic strategies.
A systematic review found that lifestyle-modification programs have no significant impact on body weight in Arab countries, highlighting the need for adapted treatment programs. The studies cited methodological flaws, including linguistic and socioeconomic context neglect, and sociocultural obstacles to female participation.
Research by American Psychological Association highlights the negative impact of fat shaming on patients' physical health and well-being. Studies show that overweight individuals may receive inadequate medical treatment, including under-dosing of antibiotics and chemotherapy, due to weight-based assumptions.
Researchers found that low leg fat mass is a crucial factor in lean individuals at increased risk of cardiometabolic diseases, similar to lipodystrophy phenotypes. The study suggests personalized prevention and treatment strategies for metabolically unhealthy lean people.
Researchers at Monash University have discovered a brain mechanism that controls the conversion of white fat into brown fat after eating, which could lead to new obesity treatments. The 'switch' is turned off during fasting and on during feeding, promoting weight gain when the switch remains active.
A new educational initiative at Touro University College of Osteopathic Medicine has significantly reduced medical students' negative attitudes toward people with obesity. The program emphasizes the complexities of obesity and focuses on attaining health instead of weight loss, leading to improved patient outcomes.
A study found that heavier Asian Americans are viewed as more American and subject to less prejudice compared to their thinner peers. Researchers believe this phenomenon is linked to common stereotypes about Asians being thin and Americans being heavy.
Research at Cornell University found that people with dulled taste buds prefer sweeter, high-calorie foods. Participants who had their taste receptors temporarily blocked consumed more sugar than those with unaltered taste response.
Researchers at Rockefeller University have discovered two brain cell populations that regulate appetite and may offer a new path to treating obesity. The study found that activating specific neurons in the dorsal raphe nucleus can suppress hunger and promote weight loss, opening up new avenues for developing effective obesity drugs.
A new study by the University of Leeds found that insufficient sleep can lead to weight gain and poorer metabolic health in UK adults. The research, which looked at over 1,600 participants, showed a significant association between short sleep duration and increased waist circumference.
A large new study shows that only one in three patients who have bariatric surgery succeed in getting their body-mass index below 30 in the first year. Patients with lower BMIs before surgery had higher odds of achieving this goal and better health outcomes, including stopping medication for high blood pressure and cholesterol.
Patients who undergo bariatric surgery are more likely to achieve a BMI of less than 30 if they have a preoperative BMI of less than 40. However, delaying surgery until higher weights can result in inferior outcomes.
A new study has found a link between adolescent obesity and an increased risk of developing colon and rectal cancer in adulthood. The study analyzed data from over 1.7 million Israeli males and females, finding that being overweight or obese at age 17 was associated with a significantly higher risk of colorectal cancer.
A new study published in Health Affairs reveals that individuals who adopt healthy behaviors such as maintaining a normal weight, not smoking, and consuming alcohol moderately can expect to live seven years longer than the general population. These extra years are spent in good health, free from disability.