Articles tagged with Obesity
Between 1998 and 2002, laparoscopic bariatric surgery operations increased from 2.1% to 17.9% of total procedures, while Roux-en-Y gastric bypass rose from 78% to 92%. This growth is attributed to surgeons' increased use of the minimally invasive technique and patients' greater acceptance of the procedure.
A cross-sectional study found that smoking was associated with increased risk of more severe psoriasis among adults. Cigarette-years significantly increased the risk of clinically more severe psoriasis, with stronger effects observed in women than men.
Researchers from University of Toronto found that environmental cues, such as portion size, palatability, and social norms, dominate eating decisions rather than physical or nutritional needs. This 'zone of biological indifference' makes individuals vulnerable to socially-based influences, leading to overeating.
A study of over 79,000 women found that prepregnancy obesity rates increased by 9.2% between 1999 and 2003, linked to higher risks of gestational diabetes, hypertension, preeclampsia, and labor complications. The trend was observed regardless of age, ethnicity, or socioeconomic factors.
A recent study found that exercise is related to gastrointestinal symptoms and protective against them, contradicting previous assumptions. Participants who engaged in physical activity experienced lower levels of GI problems, including abdominal pain, irritable bowel syndrome, diarrhea, and bloating.
Researchers discover that preventing amyloid deposition may be easier than curing established Alzheimer's disease through an immunization strategy targeting Abeta42. Additionally, a study finds that pre-treatment of patient T cells with IL-10 and vitamin D3 can overcome glucocorticoid resistance in asthma patients.
A recent study found that a genetic variation in the perilipin gene is associated with weight loss resistance, particularly in men and women who have become obese. Carriers of this gene variant lost an average of 20 pounds during a low-calorie diet, while those without it experienced significant weight changes.
A new small-scale study suggests that personal fulfillment is the strongest motivator for US adolescents to exercise. The research found that teens are more likely to participate in sports and vigorous activities if they enjoy the process and want to improve their fitness and physical skills.
Adolescents cite personal fulfillment as strongest motivator for physical activity, with weight-based motivation and peer influence also playing a role. The study's findings suggest that emphasizing personal fulfillment could be an effective approach to increasing physical activity among all youth, regardless of risk status.
This study found that current drinkers had a lower obesity risk than non-drinkers, with heavy drinkers being 46% more likely to be obese. The mechanisms behind this protective effect are not well understood.
In a study published in the Journal of Clinical Investigation, Columbia University researchers discovered that replacing leptin in lean individuals who lost weight restored fat mass and reversed metabolic changes. The findings suggest that therapeutics targeting the leptin signaling pathway may assist in maintaining reduced body weight...
Researchers found that genetically modified rats with high levels of leptin receptors didn't become obese, even on high-fat diets. This suggests that preventing the disappearance of leptin receptors may be key to controlling obesity.
Two studies by Cornell professor David Levitsky found that women who weighed themselves daily using the Tissue Monitoring System (TMS) gained less weight than those in a control group. Additionally, women who received lessons on estimating portion sizes in all-you-can-eat dining halls also showed no significant weight gain.
A USC study reveals that high sugar intake during childhood may play a key role in the development of diabetes in Latino children. The research found that children who consumed more sugary drinks had signs of decreased beta cell function, implying they were heading toward type 2 diabetes.
The study finds that unit bias affects how people perceive and consume food, with smaller portions being just as satisfying. The researchers believe this bias is culturally derived and plays a significant role in the French eating less than Americans.
Researchers found that nine modifiable risk factors contribute significantly to cancer mortality worldwide. These include low fruit and vegetable intake, physical inactivity, and exposure to urban air pollution. Implementing lifestyle and environmental interventions can prevent a substantial proportion of cancer-related deaths.
Two studies on obesity pharmacotherapy were published in the New England Journal of Medicine, exploring the efficacy of lifestyle modification and pharmacological interventions. Dr. Susan Yanovski, director of the NIDDK's Obesity and Eating Disorders Program, is available to comment on these findings.
A study published in The New England Journal of Medicine found that combining lifestyle modification with the weight loss medication sibutramine resulted in significantly greater weight loss among obese adults compared to using medication alone. Participants who kept daily food and physical activity records showed the most significant ...
A scholar argues that there is no scientific evidence to suggest people classified as 'overweight' are under direct threat from their body weight. The real causes of health issues are diet, exercise, and genetics, not body fat.
Researchers at Stanford University School of Medicine have discovered the appetite-suppressing hormone obestatin, which could clear up confusion over how hormones regulate appetite. Obestatin's effects on laboratory animals suggest it may be a key to developing effective treatments for obesity.
Researchers at The University of Manchester and The University of Maryland School of Medicine have made a breakthrough in understanding what makes a substance taste sweet. They found that sugar interacts with two types of taste receptors on the tongue, while some synthetic sweeteners only interact with one receptor. This discovery has ...
A recent study found that obesity measured by waist-to-hip ratio is three times stronger than BMI in predicting the risk of heart attack. The researchers analyzed data from over 27,000 people across 52 countries and discovered a striking correlation between waist size and cardiovascular risk.
A recent study found that waist-to-hip ratio is a stronger predictor of heart attack than BMI in diverse ethnic populations. The researchers discovered that larger waist size was harmful, while larger hip size was protective, leading to substantial reassessment of obesity's importance for cardiovascular disease worldwide.
Researchers discovered divergent neuronal pathways at the melanocortin-4 receptor (MC4R), controlling food intake and energy expenditure. The study provides new insights into the intricate process of maintaining stable body weight, with potential implications for obesity treatment.
Researchers found that the hormone PYY inhibits eating in the morning but not in the evening, resulting in mild weight loss. High doses of PYY are required for weight loss, and further studies are needed to understand its potential as a weight loss treatment.
A recent systematic review and meta-analysis of bariatric procedures found that the average percentage of excess weight loss after operation was 61 percent, with significant increases in rates of hospital admission. Patients who underwent Roux-en-Y gastric bypass surgery had a doubling of hospitalization rates compared to those before ...
A new study finds that a lower dose of orlistat can help overweight individuals lose weight and improve their health. The medication, supported by over 100 clinical studies, demonstrated significant weight loss and reductions in cholesterol and blood pressure.
Bariatric surgery procedures have increased significantly since 1998, with a notable shift towards wealthier households and private insurance. Despite this growth, disparities persist in receiving bariatric surgery, particularly among men, those with public insurance, and lower-income individuals.
A study of Medicare patients found a significant increase in bariatric surgery death rates among those aged 65 and older. The risk was highest among men and those with lower surgeon volume, highlighting the need for balanced care in high-risk populations.
The number of bariatric surgical procedures in the US has increased substantially, with gastric bypass accounting for over 80% of all procedures. Length of stay decreased, but sociodemographic disparities persist, highlighting the need for equal access to bariatric surgery regardless of sex and socioeconomic status.
A genetic study found that the enzyme stearoyl-CoA desaturase-1 (SCD-1) is three times more abundant in muscle of obese individuals than in lean individuals. This elevation in enzyme activity corresponds with diminished fat burning and changes in fat composition.
A study found that midlife obesity is significantly associated with an increased risk of developing dementia and Alzheimer's disease later in life. High systolic blood pressure, high total cholesterol levels, and clustering of these vascular risk factors also contribute to this risk.
Researchers found elevated C-reactive protein levels frequently accompanied traditional heart disease risk factors like smoking, obesity, and high blood pressure. High CRP levels were more common among those with at least one risk factor for heart disease.
Researchers have discovered the SEPS1 (Selenoprotein S) gene's role in inflammation, which is a common component of many human disorders. The study found that a genetic variation in the SEPS1 gene can lead to higher levels of inflammation and increased risk of diseases like cardiovascular disease and Type 2 diabetes.
A mutant rat model is being used to study the early vascular changes caused by obesity, which can lead to peripheral vascular disease. The research aims to prevent this condition and improve quality of life for those affected.
Researchers found that obese individuals who engaged in physical activity experienced fewer gastrointestinal (GI) symptoms compared to those with sedentary lifestyles. High body mass index (BMI) was linked to increased symptoms of irritable bowel syndrome (IBS), abdominal pain, and diarrhea.
A study of Medicare patients with heart attacks found significantly higher 30-day death rates in December compared to other months, with 22% of those hospitalized in the month dying within 30 days. The study looked for use of proven therapies but authors remain uncertain about the cause of the increased mortality rate.
This study shows that expressed attitudes can be modified by providing consensus information about the beliefs of others. The researchers found that a peer group's influence is more significant than a non-associated group in shaping attitudes towards obesity.
Australia's Director of Obesity Research highlights lack of access to life-saving bariatric surgery for those who need it most. Over 2.6 million Australians struggle with obesity, a growing public health crisis requiring urgent attention and action from hospitals and governments.
Scientists discover that amino acids enter the cell through a separate pathway than insulin, triggering the activation of S6K1 enzyme. This finding provides a potential new target for regulating obesity and insulin resistance.
A recent study published in the Journal of Applied Physiology found that visceral fat buildup is a major consequence of inactivity. The researchers discovered that increasing exercise amounts can significantly reduce visceral fat, while even moderate exercise can prevent accumulation and reverse it in some cases.
Obese patients with coronary artery disease can benefit from bariatric surgery, which leads to significant weight loss and improvements in blood pressure, cholesterol, and sleep apnea. However, diet and exercise should remain the primary approach for weight management before considering surgery.
A new study published in The American Journal of Medicine reveals that a high-carb, vegan diet leads to significant weight loss and improved insulin sensitivity. With unlimited servings of fruits, vegetables, and whole grains, this low-fat diet is also associated with lower rates of prostate cancer and various life-threatening diseases.
Researchers found that individuals' body weight influences their preference for residential locations in sprawling counties. Personal attributes like gender, age, and marital status also play a role in this decision.
The metabolic syndrome is frequently present in middle-aged subjects, coinciding with adverse cardiovascular changes, including inflammation, thickening of the heart, and atherosclerosis. Every additional component of MS increases the likelihood of cardiovascular damage.
A recent study has found that obese patients with estrogen-receptor negative (ER-negative) breast cancer are at risk of undertreatment due to reduced chemotherapy doses. The study, published in The Lancet, suggests that obese women with ER-negative disease who receive 85% or more of the recommended first course dose have significantly ...
A study published in the American Journal of Public Health found that baby boomers' obesity rates grew substantially compared to previous generations, leading to a surge in arthritis cases attributed to obesity. The researchers suggest that public health strategies could have a major impact on the lives of aging baby-boomers.
Researchers discovered that SH2-B, a protein increasing leptin sensitivity, maintains normal energy metabolism and body weight in mice. The absence of SH2-B impairs leptin signal transduction, leading to severe obesity.
Researchers found that SH2-B regulates leptin sensitivity, energy balance, and body weight in mice, leading to obesity and metabolic syndrome. The study identifies SH2-B as a critical component in maintaining leptin sensitivity, potentially serving as a therapeutic target for treating obesity and type 2 diabetes
A recent study published in The Gerontologist found that obesity has a significant impact on disability among adults aged 70+, but not on their overall life expectancy. The research, which analyzed data from over 7,000 seniors, suggests that obesity can reduce active years and increase disabled years, but does not affect mortality rate...
Malnutrition and obesity increasingly co-exist worldwide due to dietary changes and decreased physical activity. Chronic diseases like diabetes and hypertension are on the rise in low-income groups, exacerbated by food insecurity and under-nutrition.
A Duke University study found that obesity is associated with lower rates of mammograms, Pap smears, and flu shots among middle-aged women and the elderly. Despite knowing the risks, obese individuals are less likely to receive preventive services due to social stigma, avoidance of healthcare, and bias from providers.
A new analysis of existing studies reveals that individuals with overweight or obesity are at a higher risk of experiencing GERD symptoms, erosive esophagitis, and esophageal cancer. In contrast, researchers found no significant difference in mortality rates between patients undergoing peritoneal dialysis or hemodialysis for end-stage ...
A study of mice found increased body fat despite reduced calorie intake from solid food, suggesting fructose affects metabolic rate and favors fat storage. The research suggests that high-fructose corn syrup in soft drinks may contribute to obesity, with further human studies needed to confirm the findings.
A recent study found that individuals with obesity and extreme obesity are more likely to experience injuries compared to those with normal weight. Overexertion and falls were the most common causes of non-fatal injuries among obese participants, while underweight individuals reported the fewest injuries.
A study of 15,500 middle-aged men and women found that regular yoga practice was associated with a lower weight gain between ages 45 and 55. Those who were already normal weight at age 45 and practiced yoga regularly lost about 3 fewer pounds compared to non-practitioners.
Despite conflicting studies on obesity, most Americans believe it remains a serious public health issue. Approximately 75% of Americans rate obesity as extremely or very serious, and the majority think experts have accurately portrayed its health risks. However, there is mixed trust in scientific experts' advice on weight control.
A study of over 2,200 US girls found that decreased physical activity was the main reason for weight gain and obesity. Increasing physical activity by 2.5 hours of brisk walking per week could potentially prevent weight gain and reduce obesity risk during adolescence.
A recent study by the Women's Health and Aging Studies group found that obese older women are more likely to experience pre-frailty and frailty. The research also showed a strong association between frailty and conditions such as diabetes, congestive heart failure, and osteoarthritis.
A new study by Ohio State University found that dieting is linked to increased wealth, particularly among white women, but not as strongly among black men or white men. The study analyzed data from over 7,300 people and found that those who lost large amounts of weight experienced more dramatic changes in wealth.