Articles tagged with Obesity
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Research by the American Heart Association found that overweight men spent $18.41 per month on coronary heart disease-related prescriptions, compared to $9.89 for normal-weight men. The study also showed a significant increase in costs for obese men due to various health issues such as high blood pressure and sleep apnea.
A recent study published in Cancer Epidemiology, Biomarkers and Prevention journal found that obesity is associated with a higher risk of acute myeloid leukemia (AML) in older women. The study followed over 37,000 Iowa women for 14 years and found that those who were overweight or obese had a 90% increased risk of developing AML compar...
The NIH is funding a five-year study to assess the impact of local design and transportation changes on physical activity and obesity. The goal is to determine if simple changes in the built environment can enhance physical activity and reduce obesity for residents.
Researchers have found that fat buildup in the heart muscle, called lipotoxicity, is associated with metabolic irregularities and insulin resistance in obese and diabetic patients. Gene expression and protein findings provide potential long-term targets for treating heart failure, which affects 5 million US patients annually.
The study found that almost half of patients with pre-existing high blood pressure were off medications after surgery, while 92% of those with diabetes were no longer taking oral medications. Additionally, degenerative joint disease improved significantly in patients who underwent gastric bypass surgery.
Studies found that morbidly obese patients experience high rates of GERD symptoms, including heartburn and acid regurgitation. Additionally, a systematic review revealed a significant dose-dependent association between body mass index and risk of esophageal adenocarcinoma.
A study of 806 women with early stage breast cancer found that regular physical activity significantly reduced the risk of weight gain and improved breast cancer prognosis. Physical activity was assessed during an in-person interview as part of the Health, Eating, Activity and Lifestyle (HEAL) study.
Obese individuals have significantly higher one-year health care costs compared to nonobese counterparts. Prescription drugs and hospitalizations are key drivers of these increased costs. The study found obese patients had a median total healthcare cost of $585.44, while nonobese patients averaged $333.24.
A study by University of Illinois Chicago researchers found that nearly 60% of American adults have elevated blood pressure, with prevalence increasing among older adults, those with lower education levels and obesity. Awareness and management of hypertension remain low, particularly among Mexican-Americans.
A study found that surgical weight loss programs significantly improved metabolic syndrome symptoms, with a 95.6% resolution rate for patients with the condition. Laparoscopic gastric bypass surgery resulted in greater weight loss and better blood lipid profiles compared to vertical banded gastroplasty.
The melanocortin-4 receptor's (MC4R) basal activity is essential for maintaining energy balance. The N-terminal domain of the MC4R protein is responsible for this activity. Deletion of this domain impairs the receptor's ability to regulate energy homeostasis.
Researchers identify genetic mutations in the N-terminal domain of the MC4R protein that contribute to obesity, providing a promising new strategy for treating the condition. The study suggests that drugs targeting sustained low-level MC4R activity may be effective in regulating appetite.
A controlled study found that bariatric surgery is associated with an increased risk of peripheral neuropathy (PN), a condition causing pain and weakness. The study highlights the importance of nutritional counseling and follow-up care to prevent PN complications, which are largely preventable.
A recent study examining obese postmenopausal women found that visceral fat storage was the main determinant of metabolic syndrome and increased cardiovascular disease risk. High-intensity exercise and general weight reduction were identified as potential strategies to reduce this risk.
Researchers found that lean mass, intra-abdominal fat, and inflammation biomarker sTNFR1 are higher in women with metabolic syndrome, independently related to its severity. Analysis of these factors can help doctors identify postmenopausal women at increased risk for diabetes and heart disease.
A recent study published in Obesity Research found that portion control was the most effective behavior change for inducing significant weight loss among obese patients. According to lead researcher Everett E. Logue, Ph.D., portion control resulted in a 38% success rate, compared to 33% for those who did not practice portion control.
The American Academy of Family Physicians presents award-winning research papers on key medical topics such as prenatal care, diabetes management, and pain assessment. Researchers will be available to discuss their findings between presentations.
A review of 136 studies found bariatric surgery to be effective in achieving significant weight loss, with an average percentage of excess weight loss of 61.2%. The procedure also showed promise in resolving or improving four obesity-related disorders: diabetes, hyperlipidemia, hypertension, and obstructive sleep apnea.
A study published by Fox Chase Cancer Center found that obese women with early-stage breast cancer have a higher risk of death compared to their normal-weight peers. The research analyzed data from 2,010 patients and showed that obese women experienced a significantly lower overall survival rate and increased distant metastasis.
Researchers found that volunteers who consumed larger portions weighed an average of 39% more food and 273 calories per person compared to the previous week. The study suggests that larger portion sizes may be a major factor behind the rise in obesity rates among young adults.
Researchers at UT Southwestern will examine the behavioral, metabolic, and molecular mechanisms that cause obesity and related disorders, with a focus on the brain and liver. The team aims to develop state-of-the-art research programs and translate scientific findings to humans.
The study found that obese trauma patients were 6 times more likely to die from their injuries compared to non-obese patients. The researchers also discovered that the obese group had a higher incidence of multiple organ failure, with 13% experiencing this complication compared to 3% in the non-obese group.
A study found that energy intake from soft drinks in the US rose by 135% between 1977 and 2001, while milk intake decreased by 38%. This shift is linked to increased obesity rates.
Dr. C. Ronald Kahn receives the award for his groundbreaking work on insulin signal transduction and its link to diseases like diabetes, Alzheimer's, and obesity.
A study of 37,878 women found that being overweight increases the risk of diabetes by 3.2 times and obese individuals face a 9.1 times higher risk compared to normal-weight counterparts. Increasing physical activity can reduce the risk of diabetes, but it should be performed in conjunction with weight loss.
Researchers found that physical fitness was a significant predictor of cardiovascular disease risk factors and events, even after adjusting for obesity measures. Women with lower levels of physical fitness were more likely to have CAD risk factors and obstructive CAD.
Research suggests that increased physical activity is a crucial factor in preventing cardiovascular risk, regardless of body weight. Women with moderate to high levels of physical fitness had significantly greater event-free survival compared to those with low activity scores.
A rapid review of the Atkins diet suggests that it can lead to significant weight loss in the short-term, with individuals on the low-carbohydrate diet losing more weight than those on an energy-restricted low-fat diet. However, long-term effects and potential health risks remain uncertain, highlighting the need for further research.
A recent survey found that young people are more likely to smoke and have poor eating habits, with rates of obesity increasing across all ethnic groups. Despite some improvements in older adults, these unhealthy behaviors are expected to have serious consequences for future generations.
Rimonabant has been shown to improve body weight, waist circumference, lipid profiles, and glycemic control. Patients taking rimonabant 20mg/day lost an average of 8.6kg, while those on placebo gained 4.8kg.
A genetically engineered mouse with activated PPAR-delta receptor burns fat more rapidly, resulting in improved endurance exercise capabilities. This discovery may lead to new treatments for obesity and related metabolic disorders.
According to a recent study, approximately 65 million US adults now have hypertension, a 30% increase from the previous decade. The rise is largely due to the growing prevalence of obesity and an aging population.
Research links being overweight in kindergarten girls to a higher risk of behavior problems, including externalizing and internalizing issues. Low family income and maternal depression were strong predictors of these problems, contradicting the common belief that childhood obesity leads to behavior issues for both genders.
Researchers at Cold Spring Harbor Laboratory discovered a lean gene, C/EBPbeta, which helps mice live longer and weigh less. The gene's activation may help jump-start metabolism in fat cells, preventing fat accumulation. Another study found that targeting the JIP1 protein can effectively protect against obesity and insulin resistance.
Research found that obese women have a lower prolactin response to suckling, compromising milk production. This leads to a significantly shorter period of breastfeeding. The study suggests that obesity affects breast-feeding success, with overweight mothers being 2.5 to 3.6 times less successful than non-overweight mothers.
A study published in Archives of Surgery found that patients who underwent Roux-en-Y gastric bypass surgery experienced significant declines in ghrelin levels, a hormone that stimulates appetite. The findings suggest that complete division of the stomach contributes to this decline and may play a key role in weight loss.
A recent study found that nearly half of Los Angeles County residents engage in little to no physical activity, with sedentary behavior more prevalent among those with depression or poor health. The study also highlights the importance of promoting physical activity as part of overall wellness, beyond just weight loss.
A University of Washington study found that adolescent binge drinking is linked to obesity, high blood pressure, and other health issues by age 24. The study identified four distinct patterns of binge drinking among teenagers, which can have serious effects on their health.
Researchers found that artificial sweeteners impair the body's natural ability to regulate food intake and weight. They suggest focusing on calorie consumption and exercise instead of relying on diet drinks.
Researchers found that obese individuals have disrupted ghrelin patterns, with lower blood levels at night, contradicting common expectations. This discovery may lead to new targets for treating obesity and explore drugs that make people more sensitive to their internal cues.
A study using FDG-PET imaging found that brain metabolic activity increases in response to food stimulation, making it harder for those more sensitive to food to diet. The findings may lead to innovative treatment options for eating disorders.
A randomized trial of 110 obese men found that significant weight loss and increased physical activity improved erectile function and endothelial function. The study suggests that lifestyle interventions may be a safe strategy to improve erectile function and reduce cardiovascular risk in obese patients.
Recent studies have highlighted promising new treatments for obesity, including rimonabant's effectiveness in treating the condition. Additionally, researchers have discovered a lack of gut hormone PYY3-6 in obese individuals, leading to increased food intake and potential health risks associated with obesity.
A recent study published in JAMA found that lean adolescents who consume fast food are less likely to compensate for the excess energy by adjusting their daily intake compared to overweight peers. In contrast, overweight participants tend to overconsume fast food and fail to make up for it throughout the day.
Researchers discovered that healthy Asian Indian men, even those not overweight, exhibit abnormal cytokine production levels associated with insulin resistance. This metabolic issue can increase the risk of developing type 2 diabetes and cardiovascular disease.
A study found that fructose consumption can lead to decreased insulin and leptin levels, increased triglycerides, and lower ghrelin levels, all contributing to weight gain and obesity. The results suggest that frequent fructose consumption may contribute to the development of cardiovascular disease.
Researchers found a shift in burden of disease as economic growth expands, with poorer women more affected. Obesity risk increases for those in lower-middle income countries above $2,995 per capita income.
Researchers have identified a protein called RIP140 that blocks the expression of UCP1, leading to increased energy expenditure and reduced fat accumulation. This discovery could lead to novel obesity treatments by increasing the activity of UCP1.
A recent study found that obese postmenopausal women are more likely to be recalled for additional tests after screening mammographies, with women in the obese category II and III groups being 31% more likely to be recalled. Obese women also experience a 20% increased risk of false-positive mammogram results compared to underweight and...
A large prospective cohort study found that body size was more strongly associated with breast cancer risk in postmenopausal women than premenopausal women. Obesity was linked to an increased risk of breast cancer in women not using hormone replacement therapy (HRT), while those on HRT with a low BMI had an increased risk.
A study found that morbidly obese patients experience increased minimal distending pressure and exaggerated gastric accommodation during meals, leading to overeating and weight loss challenges. Researchers suggest addressing biological barriers differently through surgery or alternative methods.
Research shows that obesity-related surgeries can be completed as outpatient procedures, reducing associated costs. Adjustable gastric banding surgeries may also be suitable for certain obese patients, offering a safe and convenient alternative.
Moderately and severely obese patients experienced higher Gleason scores and rising PSA levels after surgery, indicating aggressive prostate cancer. Men with a BMI of greater than 35 kg/m2 had a 60% risk of cancer recurrence within three years.
Two studies show that women with PCOS are at higher risk for cardiovascular disease due to elevated CRP levels and metabolic abnormalities. Obese women with PCOS symptoms are particularly at risk, highlighting the need for close monitoring of CVD risk factors in this population.
A study found significant increases in blood pressure levels among children and adolescents between 1988-1994 and 1999-2000, with systolic levels increasing by 1.4mmHg and diastolic levels by 3.3mmHg. The researchers suggest that effective primary and secondary hypertension prevention programs are needed to address this trend.
A recent study found that average blood pressure levels among American children and teenagers have increased over the past two decades. The new clinical practice guidelines will provide updated recommendations for lifestyle and drug therapies to address this trend.
New Saint Louis University research reveals that high triglycerides in the bloodstream prevent leptin from reaching the brain, leading to increased hunger and weight gain. The study suggests that lowering triglyceride levels may be a key factor in solving the obesity epidemic.
Studies show that the Curves program leads to significant weight loss, increased muscle mass, and improved health markers such as blood pressure and aerobic fitness. Women participating in the program experience a 20-30% improvement in strength and a 15% increase in aerobic capacity.
Researchers found that body shape, rather than weight alone, plays a crucial role in determining cardiovascular risk. The study's findings suggest that individuals with large waists and narrow thighs are more likely to experience increased cardiovascular mortality, regardless of their overall weight.
Research suggests that higher pre-pregnancy BMI increases the risk of developing preeclampsia sharply, even within normal BMI ranges. The study found a curvilinear relationship between BMI and preeclampsia risk, with women considered 'obese' facing a three-fold increased risk.