Articles tagged with Renal Failure
Researchers have found a novel biomarker, neutrophil gelatinase-associated lipocalin (NGAL), that can detect kidney failure in children after cardiac surgery in as little as two hours. This early diagnosis enables timely administration of effective therapeutic measures to prevent further complications.
Researchers at Columbia University Medical Center discovered a protein called Ngal that can protect mice from renal failure after injection, suggesting its potential as a therapeutic tool. The study also found Ngal to be an effective marker for early diagnosis of kidney failure.
Researchers at MCG Medical Center are studying a bioartificial kidney that can mimic the functions of natural kidneys, reducing mortality rates in ICU patients. The device, developed by Dr. H. David Humes, uses billions of donor kidney cells to filter waste and regulate various bodily processes.
A phase I/II study demonstrates the bioartificial kidney's safety and effectiveness in treating acute renal failure, with six patients surviving over 30 days after treatment. The device uses human adult progenitor/stem cells to filter blood and regulate immune system molecules.
Rosuvastatin, marketed as Crestor, has been linked to a higher incidence of rhabdomyolysis and renal insufficiency compared to other statins. The drug's manufacturer, AstraZeneca, is estimated to be seeking $20 billion in annual sales, making it morally unjustifiable to keep the drug on the market.
Researchers have identified multiple families with a genetic mutation causing gout and kidney failure, developing in teenage years and progressing to end-stage kidney disease by the 40s or 50s. The team hopes to find family members who may be unaware of their condition and develop improved treatment for this rare disease.
Research finds that heavy use of analgesics for at least nine years prior to irreversible kidney failure is associated with anatomic changes of SICK. Over 7% of dialysis patients had SICK, with 33% having overused analgesics preceding dialysis start.
A new study found that 16.5% of non-kidney transplant recipients develop chronic kidney failure, with older age, being a woman, and pre-transplant hepatitis C infection increasing the risk. The risk is higher for those whose kidneys fail after transplant, highlighting the need for better treatment regimens.
Researchers found that 30% of diabetic patients with kidney disease do not exhibit common symptoms like protein in urine and eye disease. The current approach of screening for these symptoms alone is insufficient, and a blood test measuring kidney function directly is recommended.
A study published in Science suggests that proteins normally pass into the kidneys and that kidney disease may result from an inability to draw them back out. Researchers identified at least two patients with kidney disease who lack one copy of CD2AP, a protein critical for kidney function.
Researchers estimate 8 million people in the US have less than half of normal kidney function, a treatable condition. Chronic kidney disease is strongly associated with older age and non-Hispanic whites, raising concerns about minority populations' higher risk of kidney failure
A study published in JAMA found that ICU patients treated with diuretics have a 68% increase in mortality and 77% non-recovery of kidney function. The researchers suggest reassessing diuretic use, particularly for those not responding to treatment, as delays can lead to adverse outcomes.
A patient who developed kidney failure after taking Chinese herbal medicine containing aristolochic acid has now been diagnosed with kidney cancer. The authors warn of the carcinogenic potential of aristolochic acid in human beings.
A daily dose of fish oil significantly improves kidney function and reduces the risk of advanced kidney failure in people with IgA nephropathy. Researchers followed 106 study participants for over six years, finding sustained benefits from fish oil supplementation.
A low-protein diet can safely delay dialysis treatment for up to a year in patients with severe chronic renal failure. The diet, rich in fruits and vegetables, provides essential nutrients without side effects.
In a groundbreaking case, doctors at the University of Maryland Medical Center reversed kidney failure in an HIV-infected patient by putting them on high-intensity antiretroviral therapy. The patient's kidneys regained normal function, and their viral load decreased significantly.