Articles tagged with Sleep Apnea
A meta-analysis found that CPAP treatment adherence is associated with a lower risk of recurrent cardiovascular events in patients with obstructive sleep apnea. Adherence to CPAP therapy may be a key factor in secondary cardiovascular prevention.
Researchers have developed an automated breath-by-breath measure to assess the severity of obstructive sleep apnea, predicting cardiovascular disease and mortality. The ventilatory burden tool provides a validated alternative to AHI, offering stable results and risk predictions.
Research presented at the European Respiratory Society International Congress suggests that CPAP machines can prevent deaths from heart disease and reduce cardiovascular problems in people with obstructive sleep apnea (OSA). A pilot study also found that CPAP may be more effective than a weight-loss drug in tackling clogged arteries.
A study found that CPAP treatment reduces night-time heartburn, productive morning cough, and chronic bronchitis in patients with obstructive sleep apnea (OSA). Regular CPAP use decreases reflux by keeping the upper airway open during sleep.
Researchers found that telomere shortening, a biomarker of cellular aging, accelerated in untreated obstructive sleep apnea patients. However, continuous positive airway pressure (CPAP) attenuated this damage. The study suggests that CPAP can reduce inflammation and oxidative stress, leading to slower aging.
Researchers found that people with obstructive sleep apnea have a higher risk of cardiovascular disease, with reduced blood oxygen levels being the leading factor. The study suggests that treating sleep apnea could help prevent future cardiovascular outcomes.
The July issue of CHEST journal features 49 articles on clinically relevant topics, including disability rights and life-sustaining treatment. The journal offers complementary web resources, such as visual abstracts, to expand the reach of its research.
This study found that better sleep architecture and the absence of obstructive sleep apnea were associated with improved global cognition over a five-year follow-up. The findings suggest that interventions to improve sleep may be crucial for maintaining cognitive function in adults.
Researchers from Mount Sinai Health System presented new findings on the impact of customized lighting on inpatient sleep, a machine-learned combination of ventilatory, hypoxic, and arousal burdens, and the effects of obstructive sleep apnea and insomnia on cognitive impairment. The studies aim to improve sleep timing and duration, dia...
A new study published in Neurology found an association between sleep apnea and reduced brain volume, particularly in the medial temporal lobe area of the brain. People with amyloid plaques who had more severe sleep apneas were also more likely to have lower brain volumes, suggesting loss of brain cells.
Research found that low oxygen levels in infants due to sleep apnea can lead to dysregulation of the autonomic nervous system, resulting in high blood pressure. The study's findings may contribute to the development of novel therapies for patients with hypertension who do not respond well to treatment.
A new study found that obstructive sleep apnea causes widespread changes in gene activity in mice, affecting up to 16% of genes, particularly in lung tissue. The findings may lead to diagnostic and therapeutic approaches, including blood tests tracking dysregulated gene products.
A wearable device developed by Georgia Tech researchers detects obstructive sleep apnea and quality of sleep at home, addressing comfort, time, access, and cost issues. The patch has an 88.5% accuracy rate for sleep apnea detection and can predict the likelihood of developing the condition.
Research suggests that pulse oximeters used in obstructive sleep apnea tests may underestimating the severity of OSA in Black patients. This is because people with darker skin tones tend to have lower oxygen levels during breathing pauses, which can lead to misdiagnosis and inadequate treatment.
The May issue of the CHEST journal features cutting-edge research on pulmonary, critical care, and sleep medicine. The journal also highlights awareness for cystic fibrosis, a once-fatal childhood condition now affecting adults.
A large study found that adults with obstructive sleep apnea were more likely to experience long-term symptoms of COVID-19 than those without the condition. Adults with both sleep apnea and COVID-19 were up to 75% more likely to develop long COVID, according to researchers.
Adults with sleep apnea are at greater risk for long COVID, according to a new study. The research team found that patients with sleep apnea had a 12% increase in risk for long-term symptoms after their initial infection, and a 75% increase in risk compared to those without sleep apnea.
A study published in Neurology found that people with sleep apnea and less deep sleep have higher biomarkers for stroke, Alzheimer's disease, and cognitive decline. Participants with severe sleep apnea had reduced axonal integrity, similar to being three years older.
Researchers at McMaster University have found that solriamfetol is the most effective treatment for excessive daytime sleepiness (EDS) in individuals with obstructive sleep apnea (OSA). A systematic review of 14 clinical trials and analysis of data from various databases revealed solriamfetol to be the best option.
Researchers found that solriamfetol, armodafinil–modafinil, and pitolisant reduce excessive daytime sleepiness in patients with obstructive sleep apnea already using conventional therapy. However, patients may be more likely to discontinue the use of these medications due to adverse events including headache, anxiety, and insomnia.
The American Thoracic Society International Conference Abstracts publication features selected abstracts on COPD treatment, including a study on improving depression through home-based pulmonary rehabilitation. The issue also highlights recent findings on sleep apnea severity, as well as research on health equity and access to care.
High night-to-night variability in sleep apnea severity is associated with uncontrolled hypertension, increasing cardiovascular risk. The study found a 50-70% increased likelihood of cardiovascular events and mortality.
Researchers found that obstructive sleep apnea (OSA) can cause premature cognitive decline in middle-aged men, including poorer executive functioning and social cognition. The study suggests that OSA itself is sufficient to cause these deficits, rather than being solely attributed to co-morbidities.
Researchers found that women with multiple sclerosis were more likely to report sleep disorders, including obstructive sleep apnea, insomnia, and sleepiness. Insomnia mediated more than 10% of the cognitive problems reported by women with MS, while sleep apnea accounted for 34%.
A University of Ottawa study found that almost two-thirds of Canadians with stroke experience disturbed sleep, and those affected are up to 7 times more likely to report multiple sleep problems. The study highlights the need for better awareness and guidance on managing sleep disorders in stroke patients.
Researchers found that statins protected blood vessels against inflammation, reducing cardiovascular risk in sleep apnea patients. In contrast, CPAP therapy increased levels of angiopoietin-2, a protein associated with heart disease.
Scientists at Gladstone Institutes have discovered how excess oxygen changes proteins in our cells, triggering a cascade of events that damage cells and tissues. The findings have implications for conditions such as heart attacks and sleep apnea, revealing that hyperoxia is not solely caused by reactive oxygen species.
A new study found that poor sleep is associated with compromised cardiovascular health in middle and old age, with men losing nearly 7 years of heart disease-free life compared to healthy sleepers. Women also experienced a significant loss of normal heart health, with up to 2 years lost due to general poor sleep.
A new study analyzing over 14,000 people found that parents with sleep disorders have a significantly higher risk of experiencing stress. The study also discovered that children with sleep disorders can nearly double the risk of their parents developing insomnia and sleep apnea.
A new jaw surgery technique, segmental mandibular advancement (SMA), has been shown to effectively treat moderate-to-severe Obstructive Sleep Apnea (OSA) in a pilot study. The procedure resulted in a 50% or more reduction in breathing disturbances at night for 58% of patients, with no signs of sleep apnea.
A recent study led by Stefan Seidel found that light therapy significantly improves fatigue symptoms in Multiple Sclerosis patients, with measurable improvements observed after just 14 days of use. The study used objective measurements to rule out sleep disorders, which are common comorbidities with fatigue in MS patients.
Researchers developed an app to track CPAP use, sleep patterns, and other health metrics to provide a new adherence metric that aligns therapy with individual need. This tool can help patients and providers deliver more effective sleep apnea treatment by tracking progress toward a personalized dose of therapy.
A Michigan Medicine-led study reveals that transgender youth are 5.4 times more likely to experience insomnia and three times more likely to suffer from sleep apnea compared to cisgender youth. Gender-affirming therapies may offer a protective effect against worsening sleep health, according to the researchers.
The USPSTF recommends against routine screening for obstructive sleep apnea (OSA) in asymptomatic adults and those with unrecognized symptoms. OSA is linked to various adverse health outcomes, including cardiovascular disease and cognitive impairment.
Pediatric sleep apnea can be detected with high precision using a unique gene signature that distinguishes children with OSA from healthy children. A recent study found that obstructive sleep apnea induces changes in immune cell diversity, leading to elevated levels of certain white blood cells.
Researchers at Johns Hopkins Medicine have identified TRPM7, a cation channel in carotid bodies and bloodstream, as a promising therapeutic target for sleep apnea. Blocking or eliminating this channel may offer a new treatment option for obesity-related breathing disorders.
A new study from Flinders University has shown that reboxetine, previously used to treat depression, can reduce obstructive sleep apnoea (OSA) severity. The study found that reboxetine alone reduces the number of sleep apnoea events per hour and improves oxygen levels.
Researchers found that transplanted gut bacteria from mice with obstructive sleep apnea caused increased blood pressure and impaired coronary function in recipient mice. Probiotics improved symptoms for the recipients but not the donor mice, highlighting a potential therapeutic strategy to mitigate cardiovascular disease.
A large study found that obstructive sleep apnea is independently associated with an increased risk of cancer. Patients with more severe OSA were also at a greater risk of developing blood clots. Additionally, a second study linked OSA to a decline in mental processing powers, particularly in the elderly.
A new Flinders University analysis found that people reporting symptoms of both insomnia and obstructive sleep apnea are at an increased risk of death compared to those without the conditions. The study highlights the importance of self-reported symptoms and risk factors, and could lead to greater and more rapid assessment in populatio...
The American Heart Association offers important guidance on sleep-disordered breathing and its association with cardiac arrhythmia, highlighting the potential benefits of SDB treatment on patient outcomes. The statement emphasizes the need for more randomized data to confirm the link between SDB and reduced atrial fibrillation recurrence.
The August issue of the CHEST journal features 47 articles on clinically relevant topics such as asthma, COPD, and pulmonary vascular disease. A highlighted article examines barriers to palliative care in interstitial lung disease.
A study published in PLOS ONE found an association between reduced estrogen and progesterone levels and increased risk of snoring and obstructive sleep apnea in postmenopausal women. Low estrogen levels were linked to a 19% decreased odds of snoring, while low progesterone levels were associated with a 9% decrease.
A study using PET imaging found that severe obstructive sleep apnea is associated with abnormal heart blood flow reserve, increasing the risk of heart disease. The findings suggest that cardiac PET imaging can identify high-risk OSA patients.
A new study from Tel Aviv University finds that women aged 55 and over who snore are at significant risk for sleep apnea, which can be fatal. The researchers warn that the phenomenon often occurs during sleep, causing women to be unaware of their condition.
A surgically implanted device has been found to safely and effectively reduce sleep apnea in adolescents with Down syndrome, with significant improvements in daily functioning, behavior, and language. The device, called a hypoglossal nerve stimulator, was tested in a phase I clinical trial and showed promising results.
A new study found that people with sleep apnea are more likely to engage in risky driving behaviors such as speeding and hard braking. The researchers monitored the driving habits of 96 older adults under real-world conditions and collected data on over 100,000 trips. They also assessed cognitive impairments and molecular signs of earl...
A new University of Gothenburg study has found that a drug treatment can reduce the frequency of breathing pauses in sleep apnea by an average of over 20 per hour. The treatment, which involves carbonic anhydrase inhibition, showed promising results with minimal side effects.
Researchers found that obstructive sleep apnea (OSA) accelerates the biological aging process and causes epigenetic age acceleration, leading to increased mortality risk. However, one year of CPAP treatment significantly slows down biological age acceleration in OSA patients, suggesting a potential reversal of age-related trends.
A recent study suggests a significant association between sleep apnea and joint pain in postmenopausal women, with higher respiratory distress scores linked to joint pain severity. The researchers propose that detailed examination of sleep-disordered breathing be conducted in women with severe joint pain and fatigability.
A study published in The Nurse Practitioner found that maladaptive coping strategies such as using caffeine and taking daytime naps can actually decrease sleep quality. Patients who used these strategies had longer times to REM sleep and more frequent nighttime arousals compared to those who did not use them.
Research found that pregnant women with sleep apnea are at a higher risk for developing hypertension and metabolic syndrome after delivery. A study of over 1,900 women found that those with persistent sleep apnea were three times more likely to develop hypertension and two times more likely to develop metabolic syndrome.
Researchers found no clinical improvements in very elderly patients with CPAP therapy for moderate-to-severe sleep apnea. The study suggests that CPAP treatment is less effective in patients older than 80 due to a more sedentary lifestyle and other underlying disorders, limiting its long-term adherence.
A study in rats found that mothers with sleep apnea during pregnancy may have an increased risk of their male offspring developing autism-like behaviors, including impaired cognitive and social function. The findings suggest a potential mechanism for the link between maternal sleep apnea and neurodevelopmental disorders.
Researchers at the University of Eastern Finland have developed simpler measurement technologies for diagnosing sleep disorders, enabling more accurate analyses. The new methods use reusable sensors in home environments, reducing costs and increasing patient comfort.
A study published in the European Respiratory Journal found that people with both insomnia and obstructive sleep apnoea are at a higher risk of heart problems and mortality. Participants with co-morbid insomnia and sleep apnoea were two times more likely to have high blood pressure and 70% more likely to have cardiovascular disease.
Researchers at Flinders University have developed a virtual individual patient model to predict the success of dental appliances in treating sleep apnea. The new approach uses standard testing and clinical data to create a machine learning-based model that predicts treatment outcome in about 60-100% of cases.
The November issue of CHEST journal includes 69 articles on topics such as asthma, COPD, critical care and thoracic oncology. The journal also offers complementary web and multimedia activities to expand the reach of its research.
A study published in SLEEP reveals an association between early lower respiratory tract infections and the development of obstructive sleep apnea in children. Children who had a history of severe RSV bronchiolitis during early infancy were found to have a higher risk of developing OSA.
The American Academy of Sleep Medicine has released a new clinical practice guideline recommending referral to upper airway or bariatric surgery for adults with obstructive sleep apnea who are intolerant of CPAP therapy. The guideline provides strong recommendations for treatment, considering factors such as BMI and patient adherence.