Articles tagged with Sleep Apnea
Researchers found that obstructive sleep apnea increases the susceptibility of mice to develop abdominal aortic aneurysms, likely caused by intermittent hypoxia triggering enzyme activity that degrades the extracellular matrix. This degradation weakens the aorta, making it more prone to rupture.
A clinical trial found that sulthiame, a drug used for epilepsy, reduces pauses in breathing and improves oxygen levels in patients with obstructive sleep apnea. The treatment also alleviates daytime fatigue, suggesting it could be an effective alternative to existing mechanical treatments.
Rutgers researchers suggest dentists play a crucial role in identifying and addressing sleep disorders, citing signs such as tooth grinding, tongue scalloping, or patients dozing off. With up to 80% accuracy, dental clinicians can identify at-risk patients with comprehensive care and prevent serious health complications.
A study published in Science Signaling explains the mechanism behind persistent pain related to obstructive sleep apnea. The researchers created a chronic intermittent hypoxia environment in mice and observed an increase in cytokines, which cause sensitivity in nociceptors producing prolonged pain sensitivity.
A recent study at the University of Missouri discovered that oxytocin and corticotropin-releasing hormone cause the brainstem to become overactive, leading to hypertension. This finding can help develop targeted drugs to reduce high blood pressure in sleep apnea patients.
Researchers found a correlation between high homocysteine levels and the severity of obstructive sleep apnea. The study suggests that measuring homocysteine could help clinicians predict the risk of developing severe apnea, enabling early intervention and prevention.
The WVU researchers developed a non-invasive, at-home sleep apnea detection device that uses artificial intelligence technology to measure oxygen levels in the blood. Early detection can help prevent worsening of underlying comorbid conditions and reduce healthcare costs, according to Dr. Sunil Sharma.
Researchers have developed a novel drug therapy for obstructive sleep apnea (OSA), which has shown significant improvements in reducing breathing interruptions and improving overall health. The treatment targets both respiratory and metabolic complications, providing a promising alternative to existing therapies.
A Cleveland Clinic study finds bariatric surgery cuts the risk of major cardiovascular events by 42% and all-cause mortality by 37% in patients with obesity and moderate to severe obstructive sleep apnea. The study analyzed data from 13,657 adult patients who underwent weight loss surgery between 2004 and 2018.
A new study has found a strong association between sleep apnea-induced hypoxemia and the risk of lung cancer reoccurrence. The research involved a retrospective record review of adult patients with non-small cell lung cancer, finding that measures of hypoxic burden were strongly correlated with accelerated cancer reoccurrence.
A new study has found that older adults with sleep apnea are more likely to use health services in the future, including hospitalization. The study analyzed data from nearly 20,000 participants and found a 21% higher odds of hospitalization among those with sleep apnea.
Researchers from Mount Sinai presented three studies on obstructive sleep apnea (OSA) at SLEEP 2024, exploring its effects on thalamic activity, overnight memory performance, and symptom improvement with CPAP treatment. The findings suggest that OSA can impair cognitive function and that hypoxic burden may predict clinical improvement.
A new study demonstrates that greater adherence to positive airway pressure (PAP) therapy is associated with higher levels of relationship satisfaction and lower levels of conflict among couples. The research also shows that higher sleep efficiency among patients contributes to better relationship outcomes as reported by both partners.
The American College of Chest Physicians' CHEST Critical Care and CHEST Pulmonary journals have been indexed with the Directory of Open Access Journals (DOAJ), enhancing their open access content's accessibility and usage. The indexation is attributed to strong editorial boards led by Hayley Gershengorn and Matthew Miles.
A recent UC Irvine-led study reveals a correlation between sleep apnea events during the rapid-eye-movement (REM) stage and verbal memory impairment in older adults at risk for Alzheimer's. The study found that higher ratios of apnea severity during REM compared to non-REM stages were associated with worse memory performance.
A comprehensive study by University of Technology Sydney researchers confirms CPAP therapy's safety without adverse effects on the respiratory system. The study uses computational modeling to assess airflow velocity and shear stress, providing reassurance for patients.
A study published by NIH/NINDS found that low oxygen levels while sleeping and sleep apnea are linked to late-onset epilepsy in older adults. People with nocturnal hypoxia were three times more likely to develop late-onset epilepsy, independent of other medical issues.
A new case study suggests that hypoglossal nerve stimulation can improve sleep quality and cognitive development in children with Down syndrome. The procedure has shown promising results in reducing obstructive apnea-hypopnea index and improving neurocognition, offering a potential treatment option for young patients.
A new study from Washington University School of Medicine found that nerve-stimulation treatment for obstructive sleep apnea is less effective for people with higher BMIs. The study analyzed data from 76 patients with BMIs of less than 35 and showed that the likelihood of successful treatment drops significantly as weight increases.
A new study found that children with chronic medical conditions who also have a diagnosed sleep disorder are nearly two times more likely to have increased health care utilization. The most common sleep disorder diagnosis was sleep-disordered breathing, which was present in 1,796 children.
Researchers at Flinders University have discovered a bedtime nasal spray that can reduce the severity of sleep apnea in people and lower their blood pressure. The study found that the spray, which blocks potassium channels, improved oxygen levels and reduced markers of OSA severity in 7 out of 10 participants.
A recent study published in Neurology found that white people with sleep apnea are at increased risk for stroke, while Black people with the condition have a reduced risk when using CPAP machines. The study suggests that racial differences in sleep apnea severity and treatment may impact stroke risk.
A preliminary study released by the American Academy of Neurology found a positive association between sleep apnea symptoms and memory or thinking problems. Participants who reported sleep apnea symptoms were about 50% more likely to also report having memory or thinking problems compared to those without sleep apnea symptoms.
A new study published in the American Journal of Respiratory and Critical Care Medicine found that childhood tonsillectomy is not associated with an increased risk of obesity in adulthood. The research followed 132 children who underwent tonsillectomy for obstructive sleep apnea and found no link to weight gain in adulthood.
Researchers found that high levels of pro-inflammatory factor Ang2 remain elevated in CPAP users, associated with a greater risk of cardiovascular disease. Lowering CPAP pressures may reduce inflammation and improve heart health for these patients.
A recent study by University of Missouri researcher Mansoo Yu found that online weight loss interventions with counseling and social support are effective for middle-aged adults with obesity. The study identified two key features: professional health coaching and access to social support from other users, which led to significant long-...
Researchers found that people with OSA were more likely to use multiple strategies to stay alert while driving, which can indicate excessive sleepiness. This study suggests that asking about these coping strategies in the clinic could help doctors identify patients at risk of driving incidents and advise them appropriately.
A groundbreaking study found that combining partial normoxic recovery with senolytic Navitoclax significantly reduced sleepiness and improved cognitive function in mice with OSA. This suggests targeting accelerated senescence may be a promising avenue for improving treatment outcomes.
Researchers have discovered that analyzing changes in sweat metabolism can help diagnose the severity of sleep apnea. The study, published in the Journal of Sleep Research, found that sweat samples can provide valuable insights into energy production and oxidative stress associated with the disease.
Research by Hungarian researchers found that flat-faced dogs, like French Bulldogs, sleep more due to increased daytime sleepiness and longer REM sleep phases. Their EEG patterns showed signs of white matter loss and distorted brain function.
A randomized clinical trial found that tonsil and adenoid removal surgery improved sleep quality, reduced snoring, and behavioral problems in children with mild sleep apnea. However, the surgery did not impact neurodevelopmental functioning.
A study of 2,574 participants with obstructive sleep apnea found that those sleeping less than seven hours had higher risks of all-cause mortality independent of apnea-hypopnea index. Further research is needed to investigate potential health benefits of extending sleep length among these individuals.
Researchers developed an ingestible capsule to measure vital signs from within the GI tract, detecting sleep apnea episodes and breathing rate depression. The device shows promise for early detection of respiratory changes, including those caused by opioids or asthma/COPD.
A new pill-sized device has been developed to monitor vital signs like breathing and heart rate from inside humans. The device, known as the VM Pill, was tested in a clinical trial and showed accurate results in detecting breathing stops and monitoring respiration rates with high accuracy.
Researchers developed soft, miniaturized wearables that continuously track subtle body sounds wirelessly across the body. The devices offer new functionalities and provide highly accurate, real-time evaluation of patient health.
A study published in JAHA found that sleep-related hypoxia is associated with a higher risk of developing atrial fibrillation over time. Regular screening and treatment of sleep apnea may help reduce the likelihood of AFib, especially in those already at high risk.
Researchers found that former football players with medical and mental health conditions like depression and anxiety are at higher risk of receiving an unverified CTE diagnosis. The study highlights the need for accurate diagnoses and access to proven treatments.
A meta-analysis found that CPAP treatment adherence is associated with a lower risk of recurrent cardiovascular events in patients with obstructive sleep apnea. Adherence to CPAP therapy may be a key factor in secondary cardiovascular prevention.
Researchers have developed an automated breath-by-breath measure to assess the severity of obstructive sleep apnea, predicting cardiovascular disease and mortality. The ventilatory burden tool provides a validated alternative to AHI, offering stable results and risk predictions.
Research presented at the European Respiratory Society International Congress suggests that CPAP machines can prevent deaths from heart disease and reduce cardiovascular problems in people with obstructive sleep apnea (OSA). A pilot study also found that CPAP may be more effective than a weight-loss drug in tackling clogged arteries.
A study found that CPAP treatment reduces night-time heartburn, productive morning cough, and chronic bronchitis in patients with obstructive sleep apnea (OSA). Regular CPAP use decreases reflux by keeping the upper airway open during sleep.
Researchers found that telomere shortening, a biomarker of cellular aging, accelerated in untreated obstructive sleep apnea patients. However, continuous positive airway pressure (CPAP) attenuated this damage. The study suggests that CPAP can reduce inflammation and oxidative stress, leading to slower aging.
Researchers found that people with obstructive sleep apnea have a higher risk of cardiovascular disease, with reduced blood oxygen levels being the leading factor. The study suggests that treating sleep apnea could help prevent future cardiovascular outcomes.
The July issue of CHEST journal features 49 articles on clinically relevant topics, including disability rights and life-sustaining treatment. The journal offers complementary web resources, such as visual abstracts, to expand the reach of its research.
This study found that better sleep architecture and the absence of obstructive sleep apnea were associated with improved global cognition over a five-year follow-up. The findings suggest that interventions to improve sleep may be crucial for maintaining cognitive function in adults.
Researchers from Mount Sinai Health System presented new findings on the impact of customized lighting on inpatient sleep, a machine-learned combination of ventilatory, hypoxic, and arousal burdens, and the effects of obstructive sleep apnea and insomnia on cognitive impairment. The studies aim to improve sleep timing and duration, dia...
Research found that low oxygen levels in infants due to sleep apnea can lead to dysregulation of the autonomic nervous system, resulting in high blood pressure. The study's findings may contribute to the development of novel therapies for patients with hypertension who do not respond well to treatment.
A new study published in Neurology found an association between sleep apnea and reduced brain volume, particularly in the medial temporal lobe area of the brain. People with amyloid plaques who had more severe sleep apneas were also more likely to have lower brain volumes, suggesting loss of brain cells.
A new study found that obstructive sleep apnea causes widespread changes in gene activity in mice, affecting up to 16% of genes, particularly in lung tissue. The findings may lead to diagnostic and therapeutic approaches, including blood tests tracking dysregulated gene products.
A wearable device developed by Georgia Tech researchers detects obstructive sleep apnea and quality of sleep at home, addressing comfort, time, access, and cost issues. The patch has an 88.5% accuracy rate for sleep apnea detection and can predict the likelihood of developing the condition.
Research suggests that pulse oximeters used in obstructive sleep apnea tests may underestimating the severity of OSA in Black patients. This is because people with darker skin tones tend to have lower oxygen levels during breathing pauses, which can lead to misdiagnosis and inadequate treatment.
The May issue of the CHEST journal features cutting-edge research on pulmonary, critical care, and sleep medicine. The journal also highlights awareness for cystic fibrosis, a once-fatal childhood condition now affecting adults.
A large study found that adults with obstructive sleep apnea were more likely to experience long-term symptoms of COVID-19 than those without the condition. Adults with both sleep apnea and COVID-19 were up to 75% more likely to develop long COVID, according to researchers.
Adults with sleep apnea are at greater risk for long COVID, according to a new study. The research team found that patients with sleep apnea had a 12% increase in risk for long-term symptoms after their initial infection, and a 75% increase in risk compared to those without sleep apnea.
A study published in Neurology found that people with sleep apnea and less deep sleep have higher biomarkers for stroke, Alzheimer's disease, and cognitive decline. Participants with severe sleep apnea had reduced axonal integrity, similar to being three years older.
Researchers at McMaster University have found that solriamfetol is the most effective treatment for excessive daytime sleepiness (EDS) in individuals with obstructive sleep apnea (OSA). A systematic review of 14 clinical trials and analysis of data from various databases revealed solriamfetol to be the best option.
Researchers found that solriamfetol, armodafinil–modafinil, and pitolisant reduce excessive daytime sleepiness in patients with obstructive sleep apnea already using conventional therapy. However, patients may be more likely to discontinue the use of these medications due to adverse events including headache, anxiety, and insomnia.
The American Thoracic Society International Conference Abstracts publication features selected abstracts on COPD treatment, including a study on improving depression through home-based pulmonary rehabilitation. The issue also highlights recent findings on sleep apnea severity, as well as research on health equity and access to care.
High night-to-night variability in sleep apnea severity is associated with uncontrolled hypertension, increasing cardiovascular risk. The study found a 50-70% increased likelihood of cardiovascular events and mortality.
Researchers found that obstructive sleep apnea (OSA) can cause premature cognitive decline in middle-aged men, including poorer executive functioning and social cognition. The study suggests that OSA itself is sufficient to cause these deficits, rather than being solely attributed to co-morbidities.