Articles tagged with Pathogens
A new identification tool called IDphy has been developed to accurately identify Phytophthora species, which cause significant economic and environmental losses. The tool uses data from ex-type cultures and includes features such as an interactive key, factsheets, and a mobile app.
Researchers at York University found more pathogens and parasites in urban bee populations, leading to inbreeding and reduced genetic diversity. Conservation efforts focused on green spaces and habitat connectors can help mitigate these effects.
Researchers identify OmpU protein variants associated with antimicrobial resistance in Vibrio cholerae bacteria. Understanding the evolutionary origins of AMR can inform the development of effective therapeutics against resistant infections.
Researchers at IOCB Prague have determined the first cryo-EM structures of a surface receptor of Trypanosoma brucei gambiense in complex with human complement factor C3. This discovery sheds light on how the parasite avoids clearance from the human bloodstream and survives within the immune system.
Rheumatologists are crucial in detecting neurologic Lyme disease due to its broad spectrum of symptoms and signs. Early treatment has a favorable prognosis, but delayed diagnosis can lead to severe symptoms.
A workshop at the Santa Fe Institute explores the complex interplay of contagions, including infectious diseases, social phenomena, and online behavior. Researchers aim to develop new tools to study interactions between different types of contagion.
Researchers identified a protozoan parasite as the cause of mass sea urchin die-offs in the Caribbean, which has devastating effects on coral reefs and fish populations. Healthy coral means healthy fish, and their positive impacts continue up the food chain.
Research from Lund University shows that feeding small birds during winter reduces the need to lower body temperature, allowing them to fight infections more effectively. This study highlights the importance of access to food during winter in modulating a bird's immune response and ability to combat infection.
Acylceramides and protein-bound ceramides play a vital role in forming the oral barrier, similar to their function in the skin. Researchers found that these molecules protect against pathogens, chemicals, and allergens in mice.
Researchers tracked the evolution of Staphylococcus aureus in patients with eczema, discovering rapid mutations in a gene that enables the bacteria to grow faster on the skin. These findings could lead to targeted treatments by targeting variants of S. aureus associated with eczema symptoms.
A new study found that sunflower pollen's spiny structure reduces infection of a common bee parasite by 81-94% and increases the production of queen bumblebees. The research also suggests that other flowers in the sunflower family may have similar disease-fighting powers.
A recent study found that heavy alcohol use changes signaling pathways in the brain, affecting cognitive functions like decision-making and impulse control. The mechanism involves the brain's immune system and the molecule interleukin 1β, which regulates inflammation and neurotransmitter release.
Rice University's assistant professor of computer science, Todd Treangen, has been awarded a $599,943 National Science Foundation CAREER Award to develop a comprehensive computational platform for detecting yet-unseen microbial pathogens. The project aims to characterize previously unseen pathogens that could pose a risk to humans.
Researchers at Ritsumeikan University have made a breakthrough in understanding how macrophages recognize microplastics, discovering an interaction between aromatic rings that drives this process. The study suggests that while microplastics may not induce acute inflammation, chronic exposure could lead to autoimmune diseases.
Researchers at La Jolla Institute for Immunology have developed a high-resolution view of the LCMV glycoprotein, revealing its structure and potential vulnerabilities. The breakthrough enables the development of an engineered antibody that can prevent LCMV disease, offering a new route to treatment.
Researchers analysed wastewater from 10 cities to detect chemical and biological markers of health, including pesticides, pharmaceuticals and disease-causing viruses. The study found that analysing wastewater on a large scale could spot new outbreaks of diseases in communities early on.
The CoDe tool enables precise edits to genetic codes, making vaccines safer and more effective. It can also modulate gene expression in small sections, aiding vaccine design and basic research.
Researchers aim to optimize food bacterial detection using fluorescence detection, reducing detection time and improving sensitivity. The goal is to prevent spread of foodborne pathogens and provide a safe food supply.
Researchers at Texas A&M University have created a new method to monitor flocculation and mixing in real-time, allowing for more precise control over the process. This technique reduces energy consumption by halving the workload and improving precision.
A longitudinal study reveals Yersinia pestis, the bacteria that causes plague, was reintroduced into the Danish population from other parts of Europe again and again, with devastating effects. The analysis, reported today in Current Biology, identified plague for the first time from medieval Denmark.
A North Carolina State University study shows that yam seeds wrapped in a biodegradable paper made from banana fibers and cardboard grow larger and more abundantly than those without the paper. The 'wrap-and-plant' method also reduces post-harvest loss by minimizing nematode pest effects.
Researchers analyzed data on European travellers arriving from Africa between 2015 and 2019, finding malaria as the most common arthropod-borne disease. The study highlights the importance of using travellers' health data to complement local surveillance systems in Africa.
Researchers explore CEACAM1, CEACAM5, and CEACAM6's pathological significance in cancer biology and immunology. The review highlights their interactions with pathogens and potential avenues for cancer therapy.
A genomic study of the Seattle 2017-2022 Shigella outbreak revealed its origin as international travelers from areas where Shigella was common. The study also found that multi-drug resistant Shigella has become a growing global health concern, primarily affecting men who have sex with men and those experiencing homelessness.
A team of researchers from Chung-Ang University evaluated three different MALDI-TOF MS approaches used in domestic clinical settings for the identification of molds. They compared the performance and diagnostic accuracy of the Bruker Biotyper, ASTA MicroIDSys, and Vitek MS instruments.
Researcher Dana Hawley found that finches with mild and strong conjunctivitis symptoms spread a pathogen at higher rates than healthy birds. This suggests that pathogens can evolve to cause more harm to their hosts, leading to increased transmission.
A new study found that COVID-19 primarily affected patients with a moderate to critical course, often with comorbidities, whereas many had mild courses despite metastatic melanoma and systemic therapy, recommending continued treatment whenever possible.
Researchers at Texas A&M University are testing Raman spectroscopy as a diagnostic tool for Lyme disease, which shows promise in accurately identifying infected individuals. The new test could improve Lyme disease diagnosis and treatment outcomes for both humans and animals.
Researchers developed a new way to study the sensory system used by pathogenic bacteria to infect humans. They screened thousands of peptides against a bacterial sensor and discovered 13 new human antimicrobial peptides (AMPs) that activate the sensor. The findings suggest an arms race between humans and bacteria, with each evolving ne...
Researchers found that lncRNA MVIH is overexpressed in cervical cancer tumors and associated with younger age, lymph node metastasis, tumor invasion depth, and squamous cell type. This suggests its potential as a diagnostic biomarker for cervical cancer.
Researchers at UNIGE and LMU discovered that immune system's anti-tumour activity peaks in the morning. Tumours implanted at night grew faster than those implanted in the afternoon. Administering immunotherapy treatments early morning significantly enhanced their effectiveness, suggesting a new strategy for cancer treatment.
Researchers at KAUST have discovered a key protein that acts as a master switch for plant immunity, suggesting a simpler way to develop more resilient crops. The protein, OXI1, triggers the production of immune-promoting molecules, but its overactivity can harm plants.
Researchers develop a new method to track disease-carrying mosquitoes by ingesting harmless DNA particles, providing unique fingerprints of information. This innovative approach has the potential to revolutionize mosquito-borne disease surveillance and tracking, offering insights into mosquito movement and hotspots.
A research team at the University of California, Riverside has discovered the structure of a human monoclonal antibody that protects against Crimean Congo Hemorrhagic Fever virus. The study provides insights into fighting a broad range of viral strains and could lead to targeted therapeutics for infected patients.
Researchers have detected five emerging tick-borne pathogens in Central Canada, including those causing Lyme disease and babesiosis. Climate change and habitat fragmentation contribute to the spread of these pathogens, highlighting the need for increased awareness and protection measures.
Researchers developed disease-resistant maize genotypes for smallholder farmers, increasing safe yields and reducing aflatoxin contamination. The findings offer a promising strategy to protect food security in Sub-Saharan Africa.
Researchers found that shorter flower petals reduce the transmission of a harmful pathogen, increasing larval production and bee health. Planting flowers with trimmed corollas or even distribution of nectar also supports bee well-being.
The study focuses on reducing insects and pathogens that threaten crops, with manure serving as a potential solution. Researchers will investigate the most effective ways to apply manure to improve soil health and plant resistance to insect pests.
Researchers created theoretical models to explain geographical clustering of vaccine hesitancy, attributing it to both social selection and social influence. The models found that these two processes independently generate clusters of high hesitancy, with social selection playing a key role when societies trust propaganda.
A VUB study has mapped the immune system's response to brain infections, revealing that resident macrophages play a key role in defending against pathogens. The researchers found that blood-derived immune cells can eliminate parasites, but may retain 'memory' of past infections, altering their ability to respond to future insults.
The HOMED project developed a full panel of scientific knowledge and practical solutions for managing emerging native and non-native forest pests and pathogens threatening European forests. The project's results include over 60 scientific publications, policy briefs, practice abstracts, educational videos, and tools.
A recent study led by Dr. Luis Cuello and Alain J. Labro found that a known Shaker channel mutation differs structurally from its human counterparts, with implications for drug development and ion transport mechanisms. The research reveals a unique conformation of the W434F mutant that is distinct from wild-type channels.
The COVID-19 pandemic is linked to increased malnutrition risk, as reduced access to food and healthcare worsens nutritional deficiencies. In turn, malnutrition amplifies the spread of infectious diseases, creating a vicious cycle that threatens global health.
Researchers developed a highly effective and safe Zika vaccine technology that prevents systemic infection in pregnant mice and stimulates an immunogenic reaction. The vaccine was tested in various mouse models, proving safe and protective against the virus.
Researchers at Cleveland Clinic's FRIC found that cytoskeleton disruption is a key signal for the body to respond to viruses. This discovery has potential implications for developing new anti-viral vaccines and treatments.
A team of researchers identified the clubroot pathogen in Mexico, a crucial discovery for the country's broccoli production and global supply. The study used a detection methodology developed during Covid-19, allowing for accurate identification and potential future outbreaks.
Threespine stickleback fish evolved resistance to freshwater tapeworms by forming scar tissue around them, which prevents the worms from growing. However, this defense has a significant fitness cost for female sticklebacks, as they are 80% less likely to successfully breed due to the accumulated scarring.
A team led by York University has developed a new technique to keep drinking water safe in refugee settlements using machine learning and ensemble forecasting systems. The approach can predict the probability of residual chlorine remaining in stored water, providing critical information for aid workers to ensure safe drinking water.
Researchers at the University of Tennessee are investigating the movement of amphibian pathogens in wildlife trade networks, with a focus on disease mitigation strategies. The project aims to understand how socio-economic factors impact pathogen dynamics and develop market-based mechanisms to promote healthy trade.
Research suggests that climate change may lead to the proliferation of pathogenic fungi in drying soils, which could pose a significant public health threat. The study's findings are being used to inform policymakers on the potential risks of global climate change on soil fungal communities in the US Southwest.
Scientists uncover ancient herpes DNA, revealing the virus's prehistoric origins around 5,000 years ago. The discovery suggests a link between the emergence of facial herpes and cultural practices like romantic and sexual kissing in Europe during the Bronze Age.
Cognitive impairment can lead to population declines, particularly for species relying on learning and memory. Infections can impact cognitive abilities differently across animals, depending on their survival strategy and pathogen manifestation.
A unique fungus infects common houseflies, causing them to become necrophilic and mate with infected female corpses. The longer the corpse remains dead, the more attractive it becomes to male flies, allowing the fungus to spread its spores.
A new atlas of tissue-resident memory T cells reveals their adaptation to distinct tissue environments, offering insights into immune defense strategies. The study's findings could inform the development of targeted vaccines and therapies, leveraging 'first responders' in tissues vulnerable to infection.
A WHO-supported series has collected 13,700 new database records on mosquito-borne diseases, providing valuable resource for studying and containing infectious diseases. The data can be used to train machine-learning models for vector detection and classification, improving global human health.
A new study found that the delta variant surge in the US was partially due to overestimating population immunity, with only 67% of southern New Englanders actually immune. This underestimation led to inaccurate projections and an incorrect assumption about herd immunity.
Researchers at the University of Virginia Health System have made important discoveries on the crucial role of malnutrition in global tuberculosis, highlighting how gut infections impair treatment outcomes. A new funding partnership will train Tanzanian postdoctoral researchers to work specifically on this intersection.
Emory University researchers have identified a mechanism for skin cell death that could lead to new treatments for skin infections, alopecia, hives, and potentially melanoma. The study reveals that a protein called gasdermin A induces pyroptosis in skin cells, serving as an early warning system against bacterial attack.
Researchers at Arizona State University have developed a new technique called evanescent scattering microscopy (ESM), which allows for the visualization of proteins and other vital biomolecules with unparalleled clarity. This label-free imaging method reduces light-induced heating and requires no fluorescent dye or gold coating, making...
A recent study found that microplastics in the ocean can carry land-based parasites, such as Toxoplasma gondii, Cryptosporidium, and Giardia, which can infect humans and animals. The researchers used laboratory experiments to test whether these pathogens could associate with plastics in seawater.