Add BrightSurf on Google Email

NEJM study addresses impact of Medicare Part D on medical spending

A recent study published in the New England Journal of Medicine found that Medicare Part D led to increased pharmacy spending among beneficiaries, particularly those with limited or no prior drug coverage. However, this increase was offset by decreased spending on other medical care services such as hospitalizations and doctor visits.

SourceUniversity of Pittsburgh Schools of the Health Sciences·JournalNew England Journal of Medicine·DateJul 1, 2009

NICE approves use of lenalidomide in patients with multiple myeloma who have received 2 or more previous therapies

The UK's National Institute for Health and Clinical Excellence (NICE) has approved the use of lenalidomide in patients with multiple myeloma who have received two or more previous therapies. The approval is based on robust data showing that lenalidomide can increase survival by over three months compared to dexamethasone.

SourceThe Lancet_DELETED·JournalThe Lancet Oncology·DateJun 17, 2009

Providing free drug samples to patients risks harm to public health

Researchers argue that providing free drug samples to patients is ineffective in improving access for the indigent, promotes irrational prescribing habits, and raises healthcare costs. The practice also leads to misused samples being distributed to those who cannot afford them, compromising health care quality.

SourcePLOS·JournalPLOS Medicine·DateMay 11, 2009

Women with arthritis more likely than men to stop working

A new study found that women with arthritis are more likely to leave the workforce, while men may be more likely to remain working and report negative experiences. The study analyzed data from over 9,000 individuals aged 25-64 and found that greater education was associated with being in the labor force for both men and women.

SourceWiley·JournalArthritis Care & Research·DateApr 30, 2009

Study: Treatment for acid reflux does not improve asthma

A study published in the New England Journal of Medicine found that proton pump inhibitors do not improve asthma control in patients with persistent acid reflux. Researchers examined 402 adults with asthma over 24 weeks and found no benefits from treatment, saving patients unnecessary costs and potential side effects.

SourceOhio State University·JournalNew England Journal of Medicine·DateApr 8, 2009

Pharmaceutical disobedience

A report highlights the growing trend of US healthcare consumers purchasing unapproved prescription drugs online, driven by high prices and limited access to affordable treatments. This phenomenon carries significant social and policy implications, particularly in a period of economic recession.

SourceInderscience Publishers·JournalInternational Journal of Electronic Healthcare·DateJan 27, 2009

Top-up system has hidden costs that have not been accounted for

The NHS must make substantial changes in administration and management structure to effectively manage top-up payments and keep accurate records of patient care. The cost of drugs is not the only cost to the NHS, as patients who purchase drugs and stay in the hospital reduce resources for all remaining patients.

SourceElsevier·JournalClinical Oncology·DateDec 3, 2008

New study finds publication bias among trials submitted to FDA

A recent study published in PLOS Medicine found that a quarter of submitted drug trials remain unpublished five years later. Trials with favorable outcomes were more likely to be published, while those without favorable outcomes often had outcomes omitted or altered to favor the test drug.

SourcePLOS·JournalPLOS Medicine·DateNov 24, 2008

Doctors should disclose off-label prescribing to their patients

A new study in PLoS Medicine argues that doctors should disclose off-label prescribing to patients to ensure informed consent and shared decision-making. Off-label prescriptions, which account for half of all US prescriptions, are often not supported by sound scientific evidence and can pose serious risks to patients.

SourcePLOS·JournalPLOS Medicine·DateNov 10, 2008

Diabetes treatment becomes more complex, costly

The study reveals that diabetes prescriptions increased, with more medications prescribed per patient and higher costs, from $6.7 billion in 2001 to $12.5 billion in 2007. Insulin use decreased, while the use of newer drugs like glitazones increased.

SourceJAMA Network·JournalArchives of Internal Medicine·DateOct 27, 2008

New drug class: Angina

A new drug class, ranolazine, has been approved for the treatment of chronic stable angina, providing a safe and effective alternative to existing treatments. Ranolazine has been shown to reduce anginal episodes by one attack per week and extend exercise time before an angina attack develops, with benefits seen in men more than women.

SourceThe Lancet_DELETED·JournalThe Lancet·DateOct 9, 2008

New therapy for HIV treatment

A new combination therapy using raltegravir has shown promising results in treating HIV, particularly in patients with highly resistant strains. The study found that 62% of patients achieved undetectable viral loads, while only 1 in 3 receiving a placebo showed similar reductions.

SourceUniversity of New South Wales·JournalNew England Journal of Medicine·DateJul 28, 2008

Pharmacists as educators can improve asthma outcomes

A new study found that up to 90% of people with asthma use their inhalers incorrectly, leading to poor control and increased healthcare costs. Pharmacists who received training on correct inhaler technique and provided personalized stickers for patients showed significant improvements in asthma severity and patient behavior.

SourceResearch Australia·JournalPatient Education and Counseling·DateJun 23, 2008

Higher co-payments reduce use of antidepressants

New research from Brandeis University finds that multi-tiered formularies requiring higher copayments for non-preferred medications reduce the use of antidepressants. The study, which analyzed data from a large nonprofit managed care organization, found that out-of-pocket spending increased while health plan spending per user decreased.

SourceBrandeis University·JournalThe Journal of Mental Health Policy and Economics·DateJun 6, 2008

Crystal clear savings for drug giants

A new technology developed by University of Leeds engineers can monitor crystals as they form in drug manufacture, providing a method to ensure production of desired drug compounds. This can lead to huge delays and costly challenges for drug companies, but the technology has enormous commercial potential.