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Combating counterfeit drugs

The US FDA has seen an 800% increase in new counterfeit cases between 2000 and 2006. Antimalarials are a particular target for counterfeiters, flooding the market in many Asian countries. Collaborative approaches involving governments, industries, and international organizations can help combat counterfeiting.

SourceThe Lancet_DELETED·JournalThe Lancet·DateMay 8, 2008

Relaxation training may improve control of hard-to-treat systolic hypertension

A study found that relaxation response training significantly improved treatment of isolated systolic hypertension in elderly patients. The approach reduced the need for medication and cut healthcare costs by billions of dollars. By eliciting the relaxation response, participants experienced a significant drop in systolic blood pressure.

SourceMassachusetts General Hospital·JournalThe Journal of Alternative and Complementary Medicine·DateMar 27, 2008

Sensor necklace aims to increase elderly and clinical trial participant drug compliance

Researchers have designed a sensor necklace called MagneTrace that records the exact time and date when specially-designed pills are swallowed, helping to increase drug compliance and reduce unnecessary healthcare costs. The device can notify both the patient and their doctor if prescribed dosage is not taken at the proper time.

SourceGeorgia Institute of Technology Research News·JournalIEEE Sensors Journal·DateMar 5, 2008

Rheumatoid arthritis sends many into early retirement

A new study reveals that rheumatoid arthritis results in significant economic impact due to early retirement, with up to two-thirds of costs outside the healthcare sector. Patient access to disease-modifying biologic drugs is limited, particularly in Western Europe.

SourceSpringer·JournalThe European Journal of Health Economics·DateFeb 4, 2008

Cost of glaucoma medications may impact treatment

The management of glaucoma costs the US healthcare system approximately $2.5 billion per year, with glaucoma medications accounting for 38-52% of direct costs. Non-selective ß-blockers remain the most inexpensive class of glaucoma medications, while brand-name ß-blockers are consistently more expensive than their generic counterparts.

SourceElsevier Health Sciences·JournalAmerican Journal of Ophthalmology·DateDec 28, 2007

Dramatic hike forecast for ADHD drugs spend

A new study predicts a 10-fold increase in ADHD prescription costs for the NHS, rising from £7m to £49-101m by 2012. The research modelled various scenarios and considered factors such as drug availability, diagnosis rates, and treatment levels.

SourceBMC (BioMed Central)·JournalChild and Adolescent Psychiatry and Mental Health·DateNov 14, 2007

Cost of AIDS drugs in Brazil, and more

A study found that Brazil's strategy of negotiating AIDS drug prices with multinational companies and producing generic drugs locally saved the country approximately $1 billion between 2001 and 2005. However, recent years have seen a significant rise in total AIDS drug costs, driven by increasing treatment numbers and longer life expec...

SourcePLOS·JournalPLOS Medicine·DateNov 12, 2007

Study finds multiple neglected tropical diseases effectively treated with drugs

Researchers have discovered that treating two or more neglected tropical diseases simultaneously with existing oral drug treatments can be effective and efficient. The treatment approach has the potential to save millions of lives annually, particularly in Africa where nearly 500 million people are at risk for these diseases.

Many in Africa don't continue HIV treatment

A study published in PLOS Medicine found that over one-third of patients receiving HIV medication in Africa discontinue treatment within two years. However, the average retention rate at two years was estimated at 61.6%, indicating some success in maintaining treatment. Researchers suggest improving retention rates by starting treatmen...

SourcePLOS·JournalPLOS Medicine·DateOct 15, 2007

Patients can't recall their medications to tell doctors

A Northwestern University study found nearly 50% of patients taking antihypertensive drugs can't accurately name a single medication, highlighting the need for improved medication reconciliation. Patients with low health literacy were more likely to be prescribed multiple medications and have higher blood pressure.

SourceNorthwestern University·JournalJournal of General Internal Medicine·DateOct 11, 2007

New clinical guideline for low-back pain

The new guideline recommends clinicians rely on evidence-based therapies, limit X-rays, and consider non-pharmacologic options like exercise therapy, chiropractic care, and massage. The guidelines aim to reduce unnecessary radiation exposure and improve patient outcomes for low-back pain treatment.

SourceOregon Health & Science University·JournalAnnals of Internal Medicine·DateOct 2, 2007

Influence of drug companies on medical literature

A systematic review of physician awareness found doctors underestimate expensive drugs' costs and overestimate inexpensive ones. Meanwhile, a policy paper reveals drug companies control research, writing, and publication of medical articles, often using medical education and communication companies to promote their interests.

SourcePLOS·JournalPLOS Medicine·DateSep 24, 2007

Hypertension: Uncontrolled and taking over the world

The Lancet Editorial warns that hypertension's increasing burden will largely stem from poor lifestyles, with a staggering 90% risk of developing the condition in developed countries. Effective treatments exist, yet many patients misbelieve they can 'cure' hypertension and stop medication when their blood pressure falls.

SourceThe Lancet_DELETED·JournalThe Lancet·DateAug 16, 2007

Controlling prescription drug expenditures: a case report of success

A three-year observational study at Wake Forest University Baptist Medical Center found that a combination of strategies, including reclassifying brand-name drugs and removing non-essential medications from the formulary, resulted in significant cost savings. The plan's approach preserved members' use of medications for chronic conditi...

SourceAtrium Health Wake Forest Baptist·JournalThe American Journal of Managed Care·DateAug 7, 2007

Older is better -- Top-10 comparison of diabetes drugs give metformin top grade

A study by Johns Hopkins Medicine found that metformin, a widely used diabetes medication, offers distinct advantages over nine other medications in controlling blood sugar levels, weight gain, and bad cholesterol levels. The medication was also found to be less expensive than newer options, with annual treatment costs averaging $100.

SourceJohns Hopkins Medicine·JournalAnnals of Internal Medicine·DateJul 24, 2007

A mandate to reduce drug costs

A Norwegian regulation requiring doctors to prescribe thiazides as first-line treatment for hypertension has led to substantial savings in drug costs. The study found that the proportion of patients prescribed thiazides increased from one in ten to one in four, and blood pressure goals were met by a slightly higher percentage.

SourcePLOS·JournalPLOS Medicine·DateJul 9, 2007

Split the difference: Pill-splitting study looks at cost-saving step that could be used by millions

A new University of Michigan study shows that pill-splitting, slicing high-dose pills in half, can save Americans thousands of dollars on prescription drugs. Most participants said they would continue splitting pills if given a 50%-co-pay reduction, but some reported no issues with the practice.

SourceMichigan Medicine - University of Michigan·JournalThe American Journal of Managed Care·DateJun 11, 2007