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Science News for October 1, 2007


Combination of medication and psychotherapy appears most effective for treatment of depressed teens

A randomized controlled trial shows that combination therapy with fluoxetine and cognitive behavior therapy is more effective than either strategy alone in treating adolescents with depression. This study suggests that cognitive behavior therapy may protect against treatment-emergent suicidal events in patients taking fluoxetine.

SourceJAMA Network·JournalArchives of General Psychiatry·DateOct 1, 2007

Beyond a 'speed limit' on mutations, species risk extinction

A team of Harvard researchers has found that organisms must stay below a mutation rate of 6 per genome per generation to prevent extinction. This discovery explains why some species are more resilient to genetic changes and offers insights into the physical properties of genetic material and its impact on survival fitness.

SourceHarvard University·JournalProceedings of the National Academy of Sciences·DateOct 1, 2007

Early family intervention alters preschoolers' biological response to stress

A new study found that early family intervention can alter children's biological response to stress, leading to improved behavior and reduced risk of delinquency. The intervention, which includes parenting strategies and social skills training, resulted in increased cortisol levels in anticipation of a socially stressful situation.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalArchives of General Psychiatry·DateOct 1, 2007

Noninvasive tests for cirrhosis may help to avoid liver biopsy

Researchers have found promising results with three new non-invasive imaging tests that can diagnose fibrosis and cirrhosis of the liver without a biopsy. Ultrasound-based transient elastography was accurate in identifying patients with cirrhosis, while MR elastography showed nearly 100% accuracy in detecting any degree of liver fibrosis.

SourceElsevier·JournalClinical Gastroenterology and Hepatology·DateOct 1, 2007

Scientists uncover Inca children's countdown to sacrifice

Researchers analyzed hair samples from child mummies found in the Andes, revealing a 'fattening up' process before sacrifice. The children were likely chosen from peasant backgrounds and had their status raised through diet changes and symbolic cutting of their hair.

SourceWellcome Trust·JournalProceedings of the National Academy of Sciences·DateOct 1, 2007

Stanford researchers find way to fight treacherous hepatitis B

A team of researchers at Stanford University School of Medicine has identified the most cost-effective way to fight treacherous hepatitis B by screening chronically infected individuals. Screening is more effective than vaccination in reducing mortality from hepatitis B, and vaccinating close contacts also provides significant benefits.

SourceStanford Medicine·JournalAnnals of Internal Medicine·DateOct 1, 2007

Highlights from the October 2007 Journal of the American Dietetic Association

A study compared the dietary quality of popular weight loss diets, finding that some plans scored high on a cardiovascular disease-reducing index. Another study found that substituting canola oil for other vegetable oils increased compliance with fatty acid dietary recommendations, potentially reducing heart disease risk.

SourceAmerican Dietetic Association·JournalJournal of the American Dietetic Association·DateOct 1, 2007

JCI table of contents: Oct. 1, 2007

Data suggests MIF may provide a target for developing therapeutics to treat West Nile Virus encephalitis. Abnormal microglial cell migration is also implicated in age-related macular degeneration, with CX3CR1-dependent accumulation linked to disease progression.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateOct 1, 2007

UMass Medical School study identifies the best weight-loss plans for heart health

A new study by UMass Medical School researchers found that certain popular weight-loss plans significantly outperform others in reducing cardiovascular disease risk. The Ornish, Weight Watchers High Carbohydrate, and New Glucose Revolution plans scored highest due to their emphasis on whole grains, fruits, and vegetables.

SourceUMass Chan Medical School·JournalJournal of the American Dietetic Association·DateOct 1, 2007

From brains to behavior: Cold Spring Harbor Protocols features methods for neuroscience research

Cold Spring Harbor Protocols features two new methods for neuroscience research: a step-by-step approach to prepare brain slices from rats or mice for growth in culture and how to properly assess courtship behavior in male fruit flies. These protocols allow researchers to examine the structure and function of neurons in their native en...

SourceCold Spring Harbor Laboratory·JournalCold Spring Harbor Protocols·DateOct 1, 2007

Combination therapy reverses effects of portal hypertension in rats

Researchers found that a combined treatment with rapamycin and Gleevec significantly reduced splanchnic neovascularization and portal pressure in rats with established portal hypertension. The combination treatment was more effective than using either drug alone, suggesting a potential new approach for treating human patients.

SourceWiley·JournalHepatology·DateOct 1, 2007

Poor health care access common among youth leaving foster system

A recent study found that foster youth who leave the system are more likely to experience homelessness and have unstable housing situations, leading to higher rates of uninsuredness and unmet medical needs. Approximately half of emancipated participants were still in the foster care system, highlighting the need for continued support.

SourceJAMA Network·JournalArchives of Pediatrics and Adolescent Medicine·DateOct 1, 2007

Genes may hold the keys to how humans learn

Scientists have identified three genes associated with dopamine functioning in the brain, predicting individual differences in learning behaviors. These genes affect implicit reward learning and change choice strategies after negative feedback. The study offers insights into the genetic basis for learning differences and potential impl...

SourceUniversity of Arizona·JournalProceedings of the National Academy of Sciences·DateOct 1, 2007