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New asthma inhaler propellant effective, but costlier

A new asthma inhaler propellant is safe and effective, but its higher cost will significantly impact consumers and healthcare systems. The switch from chlorofluorocarbon (CFC) to hydrofluoroalkane (HFA) propellant may lead to increased costs for patients with prescription benefit plans, as well as co-pays.

SourceUniversity of Florida·JournalNew England Journal of Medicine·DateMar 28, 2007

New forecasting tool could reduce drug development costs

Researchers developed a Bayesian network model to forecast the success of new drugs, reducing mean capitalized expenditures by an average of $283 million per successful new drug. More data sharing by the pharmaceutical industry could improve forecasting accuracy and benefit patients by eliminating unsafe investigational new drugs.

SourceBoston Children's Hospital·JournalNature Reviews Drug Discovery·DateFeb 1, 2007

Combination therapy reduces exacerbations in severe COPD

A study published in the American Journal of Respiratory and Critical Care Medicine found that combining a long-acting bronchodilator with an inhaled corticosteroid reduced exacerbations by 35% in patients with severe chronic obstructive pulmonary disease (COPD). The treatment was well-tolerated, but raised concerns about potential sys...

SourceAmerican Thoracic Society·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateJan 15, 2007

Older medication may be more cost-effective for some patients with schizophrenia

A new study suggests that older antipsychotic medication perphenazine is less expensive and equally effective as newer medications for treating schizophrenia. The study, funded by the National Institutes of Health, found that total monthly health costs were up to 30% lower for patients taking perphenazine compared to those taking secon...

SourceNIH/National Institute of Mental Health·JournalAmerican Journal of Psychiatry·DateDec 1, 2006

Hope remains for Alzheimer's sufferers

Recent research published in the Lancet has shown that nursing home patients with severe Alzheimer's disease experienced significantly improved cognitive function when treated with donepezil. Additionally, data suggests that these drugs are effective in patients with milder forms of Alzheimer's disease, sparking hope for a potential re...

SourceFuture Science Group·JournalFuture Neurology·DateOct 30, 2006

ADHD costly before and after diagnosis

Children with attention-deficit/hyperactivity disorder (ADHD) experience increased healthcare costs in the two years before and after diagnosis compared to those without ADHD. White children have higher expenses than other ethnicities, reflecting a possible cultural factor in treatment acceptance.

SourceJAMA Network·JournalArchives of Pediatrics and Adolescent Medicine·DateOct 2, 2006

Sister, can you spare a million?

A study published in Circulation found that the financial burden on women with chest pain and blocked coronary arteries can total more than $1 million during their lifetime. Women with nonobstructive coronary artery disease also face significant costs, including higher drug expenses.

Over-the-counter decongestant equals prescription drug in relieving hay fever symptoms

A University of Chicago study found that daily doses of pseudoephedrine hydrochloride were as effective as montelukast sodium in relieving hay fever symptoms without additional side effects. Pseudoephedrine was slightly more effective in reducing congestion and had a lower risk of sleep problems compared to montelukast.

SourceUniversity of Chicago Medical Center·JournalArchives of Otolaryngology - Head and Neck Surgery·DateFeb 20, 2006