The Alliance for Clinical Trials in Oncology has several active trials specifically designed to help people with head and neck cancers. Trials include testing high-dose prophylactic gabapentin to prevent opioid use during treatment, as well as immunotherapy with nivolumab and cabozantinib for mucosal melanoma and nasopharyngeal carcino...
Research shows that nine weeks of Nordic hamstring exercise training increases eccentric knee flexor strength and allows participants to control the exercise through a greater range of motion. The study found that muscle fibers can stretch to longer lengths during exercise without overstretching, reducing injury risk.
Research suggests that exercising at a time that matches an individual's natural chronotype (morning or evening alertness) can lower cardiovascular disease risk. The study found that chronotype-aligned exercise improved blood pressure, fasting glucose, cholesterol levels, and sleep quality more effectively than mismatched timing.
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A new study shows that poststroke environmental enrichment reduces chronic inflammation and promotes sustained sensorimotor recovery in mice. The study found that enriched environment mice had better neurological scores and stronger recovery compared to standard environment mice.
Combining resistance training and aerobic exercises significantly enhances aerobic fitness, muscle strength, and walking distance in heart failure patients. Adding resistance training to aerobic workouts increases muscle strength more than exercising aerobically alone.
A new longitudinal study from Université de Montréal finds that three simple movement habits in toddlerhood significantly predict a more physically active lifestyle in adolescence. Active play with parents, limited screen time, and sufficient sleep are key predictors of later physical activity levels.
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A meta-analysis of millions of community-dwelling adults found that regular physical activity, less sedentary time, and appropriate nightly sleep (7-8 hours) were associated with a lower subsequent risk of dementia. Conversely, too little or too much sleep was linked to an increased risk, highlighting the importance of optimal sleep du...
A new study reveals that walking is the most popular leisure-time physical activity among US adults, but urban residents are more likely to meet exercise guidelines. Rural residents tend to prefer activities like gardening and hunting, with lower rates of inactivity and guideline adherence.
A review of international studies found that regular physical activity, a Mediterranean-style diet, and stress management can help reduce endometriosis-related pain and improve quality of life. The study also introduces the fasting-mimicking diet as a potential approach for managing gynecological conditions.
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A new international study by Adelaide University researchers found that genetics influence how lifestyle-behavioural factors impact ageing. Healthier ageing is associated with greater physical activity, better diet, and higher educational attainment, while smoking and suboptimal sleep duration have negative effects.
Researchers found that adults with type 2 diabetes who switched from dulaglutide to tirzepatide reported improved emotional responses and a greater quality of life. The study suggests that tirzepatide may offer broader benefits beyond glucose control, improving patients' physical and emotional well-being.
Research found that people who spend a higher proportion of their total physical activity doing vigorous activity have substantially lower risks of all eight serious health conditions. The benefits of vigorous activity remained even when the amount of time was modest.
A review highlights the importance of healthy lifestyles in reducing the risk of cardiovascular disease and type 2 diabetes. Adhering to optimal lifestyle factors, such as a heart-healthy diet, regular physical activity, and adequate sleep, can dramatically lower disease incidence.
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A new study published in PLOS Medicine found that consistently meeting physical activity guidelines throughout middle age reduces women's risk of dying from any cause by half. The study, which tracked over 11,000 Australian women, also found strong benefits for cardiovascular disease and cancer mortality.
A UTEP study reveals that six weeks of boxing training can reduce blood pressure and improve vascular function in young adults with elevated blood pressure or Stage 1 hypertension. The results show significant reductions in systolic and diastolic blood pressure, comparable to those achieved through medication.
A systematic review of experimental studies found exergames to be associated with better mood outcomes, including reductions in tension and depressive symptoms. The evidence base remains small and heterogeneous, but the study calls for longer-term interventions and larger samples to determine the durability of benefits.
A study found that high screen time and low physical activity are strongly linked with cardiovascular risk among young adults. Screen time was independently associated with markers of cardiovascular risk, even after accounting for differences in daily physical activity.
A multicenter randomized clinical trial found no significant differences in cognitive improvement between exercise, intensive pharmacological reduction of cardiovascular risk factors, or both in older adults. The study results challenge current recommendations on lifestyle modifications for dementia prevention.
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Researchers found that exercise and aggressive cardiovascular risk reduction improved heart health, but did not produce measurable cognitive benefits over two years in older adults at risk for Alzheimer's disease. The study highlights a critical gap between vascular risk reduction and brain health.
Adolescents who replaced half an hour of sedentary behaviors with moderate-to-vigorous physical activity or sleep showed a 15% lower insulin resistance. This study highlights the importance of being active early in life for long-term health, aligning with the American Heart Association's Life's Essential 8 metrics.
A 45-year study found that early life leisure-time physical activity is linked to better work ability in late adulthood. Higher levels of activity throughout the lifespan contribute significantly to work ability, with a dose-response association observed in late adulthood.
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Professional dancers experience high levels of physical strain and ergonomic stress, with 25% developing osteoarthritis by their late twenties. The study suggests optimizing training sessions, flooring, and organizational changes to reduce injury risk and wear-related conditions.
Research suggests that limiting sedentary time to eight hours and increasing light physical activity to seven hours a day can reduce the risk of hypertensive disorders during pregnancy. The study found incremental associations between more physical activity and lower risk of developing preeclampsia or gestational hypertension.
Regular morning exercise is associated with lower rates of coronary artery disease, high blood pressure, and obesity compared to later-day exercise. Morning exercise timing may be an underappreciated aspect of cardiometabolic health.
Maintaining a healthy lifestyle, including a high-quality diet, moderate exercise, and low alcohol consumption, was associated with lower cardiometabolic disease risk. The study found that adhering to these healthy behaviors reduced the risk of major cardiometabolic diseases independent of medication use.
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Research in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging reveals that lifetime physical activity can reshape neural connectivity, strengthening the brain's internal communication and optimizing its response to stress. The study challenges traditional deficit-focused views of adversity, offering a more dynamic and hope...
The new guidelines, based on 137 systematic reviews, emphasize the importance of consistency and effort in resistance training. The primary goal for most adults should be to build a consistent routine, which can be achieved with elastic bands, bodyweight training, or home-based routines.
A new platform, Build Better Bones, offers evidence-based guidance and practical resources for osteoporosis management. The platform, developed by the International Osteoporosis Foundation, provides a trusted place for people with osteoporosis to start their journey, with a focus on exercise, nutrition, and home safety.
Researchers found that patients who followed an exercise prescription while receiving chemotherapy reported fewer problems with thinking and memory and felt less mentally tired. The study suggests that exercise may help people with cancer stay mentally sharp and better able to handle daily tasks.
The study highlights the importance of personalized features in healthcare apps to promote physical activity. Key findings include the need for educational components, timely feedback, and tailored exercise suggestions to support users' daily routines and work demands.
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Researchers from the University of Kansas used motion capture technology to analyze shooting mechanics, finding that greater flexibility in the preparatory phase is crucial for accuracy. The study's findings will be used to attempt a new world record for most consecutive made three-point shots.
A new study found that voluntary exercise reshapes the gut microbiota, leading to changes in tryptophan metabolism and serotonin signaling. Exercise decreased the relative abundance of certain bacterial genera, shifting neuroactive signaling and lowering a key receptor in the memory center of the brain.
A single session of exercise produces a burst of high-frequency brain waves, called ripples, in brain networks tied to learning and recall. The study, led by the University of Iowa, shows that even a single bout of exercise can rapidly alter neural rhythms and brain networks involved in memory and cognitive function.
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A low-cost digital intervention increased expectation to adopt health behaviors among adults using GLP-1RAs, with effects persisting for 2 weeks. The written microsteps intervention plus short video boosters may play a role in promoting sustained behavior change.
A new study shows that high-intensity interval training increases the number of mitochondria and expands the active membrane, enhancing energy production and potentially improving endurance. The findings, published in the University of Southern Denmark, also suggest that muscle mitochondria are more adaptable than previously thought.
A new study by UCL researchers found that increasing physical fitness leads to a bigger release of brain-boosting proteins after just one session of exercise. The 12-week training program improved cognitive function and boosted brain-derived neurotrophic factor (BDNF) levels, supporting the formation of new neurons and maintaining brai...
A comparative effectiveness study found that lower music volume levels in group fitness classes did not significantly impact perceived exercise intensity. The research suggests implementing safer sound practices and increased awareness on hearing protection to minimize the risk of noise-induced hearing loss.
Structured exercise improves depression, psychotic symptoms, cognitive performance and cardiometabolic health in people with mental illness. Integration into psychiatric care using the 5A model can help address lack of exercise as a symptom and risk factor, reducing mortality.
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A comprehensive study of collagen supplements found benefits in skin elasticity, hydration, and osteoarthritis symptoms. However, there were no meaningful improvements in sports performance or muscle recovery, dispelling some myths surrounding its use.
A large review of studies found no consistent effect of music on focus or mood during exercise, with results varying depending on intensity and participant characteristics. The findings suggest that broad claims about music's benefits are not always supported and highlight the need for more rigorous study designs.
A systematic review categorizes EEG studies in shooting sports into four main directions, revealing brain plasticity principles and neural efficiency mechanisms underlying exceptional performance. Elite shooters exhibit enhanced activation in the right brain hemisphere, synchronizing alpha rhythms to suppress irrelevant thoughts.
A ketogenic diet reduced high blood sugar and improved aerobic capacity in mice with hyperglycemia. The diet caused remodeling of their muscles, making them more oxidative and reactive to aerobic exercise. Researchers believe that combining the keto diet with exercise may be key to achieving optimal health benefits.
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A new study published in Science Advances has shed light on how the body responds to energy demands from exercise, identifying a crucial cell signaling mechanism that could lead to a new treatment for diabetes. The research focuses on Adenosine Monophosphate-Activated Protein Kinase (AMPK), a regulator of energy production, and reveals...
A new study by Harvard T.H. Chan School of Public Health and the Department of Veterans Affairs Boston Healthcare System found that using GLP-1 receptor agonists in combination with adhering to healthy lifestyle habits significantly reduces cardiovascular risk among individuals with type 2 diabetes. The study showed that these two stra...
A new study shows that exercise during chemotherapy measurably improves quality of life for women with breast cancer, with benefits consistent across physical, emotional and mental health domains. The findings support existing clinical guidelines and provide clarity on the effectiveness of exercise interventions during treatment.
A six-month study found that consuming 43 grams of peanut butter daily significantly increased muscle power in older adults. This improvement enables them to perform daily activities like stair climbing and rising from a chair more efficiently.
A new poll finds that pets contribute to healthy aging benefits for older adults, including increased sense of purpose and reduced stress. However, 31% of pet owners aged 50+ report that owning a pet strains their budget, mainly due to financial costs.
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A team of researchers from The Jackson Laboratory and the University of Pennsylvania have discovered that specialized neurons in the brain's hypothalamus play a crucial role in signaling the body to start the recovery process after exercise. These neurons, which express a protein called steroidogenic factor-1 (SF1), become active for a...
A new machine learning model interprets leg motion as expended energy, providing a more accurate measure of calories burned. The device has been shown to have double the accuracy of commercial smartwatches and activity trackers.
A study found that ultra-endurance running damages red blood cells, reducing their ability to carry oxygen and nutrients. The damage accelerates the aging and breakdown of these cells, with longer races leading to greater damage.
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A Finnish study found that verifying adolescents' maximal oxygen uptake requires a brief phase to ensure reliable results. The researchers also discovered that different time averaging strategies can significantly affect the final measurement values, highlighting the need for explicit strategy specification.
Daily exercise and protein-rich drinks showed significant health benefits for people with dementia. Participants improved physical ability and required less care time in dementia wards compared to control groups. The study suggests that improved function can affect the amount of support needed.
Scientists have discovered a mechanism that explains how exercise improves cognition by shoring up the brain's protective barrier. The study found that an exercise-induced liver protein strengthens the blood-brain barrier, reducing inflammation and cognitive decline associated with Alzheimer's disease.
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Researchers report a significant association between muscle strength and lower mortality risk in women aged 63-99 years. Grip strength and chair stands were found to be key indicators of muscular strength, with even small improvements leading to notable reductions in death risk.
A systematic review suggests that exercise has small, short-lived effects on knee osteoarthritis pain compared to placebo or no treatment. Moderate certainty evidence indicates negligible effects for hip and small effects for hand osteoarthritis. The findings question the universal promotion of exercise as a first-line treatment.
The study reveals that no two sprinters look the same at full speed due to unique interactions between body, environment, and training history. By embracing movement variability and individuality, coaches can create learning environments that allow athletes to discover efficient techniques.
A new study published in JAMA Network Open found that muscular strength is associated with lower mortality rates in women aged 63-99. Controlling for physical activity and other factors, researchers discovered a significant link between muscle mass and reduced mortality risk.
Researchers found that exercise changes brain activity in nerve cells called SF1 neurons, which helps muscles and hearts become stronger. This brain region plays a key role in regulating energy use and body weight.
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A new global study finds that physical inactivity is a significant driver of diabetes complications, with up to 10% of cases potentially preventable. The research emphasizes the need for tailored approaches to promote physical activity among people with diabetes, particularly addressing social and gender inequalities.
Exercise has a medium-sized effect on depression symptoms and a small to medium-sized effect on anxiety symptoms, with aerobic formats being the most effective for relieving depression. All forms of exercise are as good as or better than medication or talking therapies for easing symptoms, regardless of age or sex.