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More than half the US population is sensitive to one or more allergens

A new study by researchers at NIEHS found that over half of the US population is sensitive to one or more allergens. The prevalence of positive skin test responses was significantly higher in NHANES III than in NHANES II, coinciding with an increase in asthma cases between 1980 and 1996.

New food allergy research consortium focuses on peanut allergy

A new research consortium will investigate basic immunologic mechanisms associated with food allergy and test novel therapies to treat peanut allergy. The consortium will conduct clinical studies, observational studies, and develop educational programs for parents, children, and healthcare providers.

Day care settings are a significant source of indoor allergens

A recent study found that day care centers are a major source of indoor allergens, with detectable levels of various allergens present in every facility. The study also discovered significant differences between carpeted and non-carpeted surfaces, with lower concentrations of allergens on non-carpeted surfaces.

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Suppressing the cells that trigger cat allergy

Researchers from Imperial College London identified a population of T cells that can suppress the proliferation of allergen-reactive T cells in vitro. This finding suggests a potential new approach to treating cat allergy, which has become more frequent in industrialized countries.

Novel therapy tested in mice could chase away cat allergies

Researchers develop injectable treatment that blocks release of histamine, a key chemical causing allergy symptoms. The treatment, GFD, successfully prevents immune cells from reacting to cat allergen in both passively and actively allergic mice.

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Allergen exposure in inner cities varies throughout the U.S.

A new study found that inner city children in the US are exposed to different levels of indoor allergens depending on their location and home type. Cockroaches were found to have the greatest impact on asthma morbidity, causing more severe symptoms and increased healthcare visits.

Sniffing out the culprits of dust allergies

A team of scientists has developed a novel method to detect the culprits behind dust allergies, using PNA-encoded protease substrate microarrays. This innovative approach reveals the specific proteins responsible for triggering allergic reactions in humans, providing new insights into the mechanisms underlying dust allergy.

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Changes in home environment can reduce asthma symptoms in inner-city children

A study published in the New England Journal of Medicine found that reducing allergens and tobacco smoke in the home can significantly reduce asthma symptoms in African-American and Hispanic children. The research involved over 900 children aged 5-11, who were randomly assigned to either an intervention group or a control group.

Reducing allergens in the home helps inner-city children with asthma

A National Institutes of Health study found that reducing indoor allergens in the home significantly improves asthma symptoms in inner-city children. By targeting common allergens like dust mites, cockroaches, and tobacco smoke, researchers helped alleviate symptoms comparable to those achieved with asthma inhalers.

Customized program reduces asthma symptoms in inner-city children

A study found that a customized environmental intervention reduced asthma symptoms in children by 21 days per year, with rapid improvements starting just 2 months after the program began. The program, which included measures to reduce allergens and tobacco smoke, was more effective than previous studies.

Pollen-blocking cream may help reduce allergy symptoms

Researchers found that a new ointment, applied inside the nose, significantly reduced symptom scores in patients with allergic rhinitis. The treatment improved airflow by nearly 20 percent and reduced symptoms by about 60 percent compared to a placebo.

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New tests for nut allergens

Researchers have developed new tests that can detect trace amounts of common tree nut allergens, such as almonds, cashews, and walnuts. These tests could lead to more accurate food labeling and reduced risk of cross-contamination in processed foods.

National study shows 82 percent of U.S. homes have mouse allergens

A recent study by Cohn et al. found that 82 percent of U.S. homes contain mouse allergens, with kitchen floors being the most contaminated area. The study, conducted across the entire country, highlights the need for clinicians to consider rodent and cockroach problems as risk factors when treating allergy and asthma patients.

Antibiotics alter GI tract microbes and increase lung sensitivity to allergens

Researchers found that antibiotics can alter the gut microbiome, leading to increased lung sensitivity to allergens. This disruption can trigger a hyperactive immune response, producing allergy symptoms or even asthma. The study suggests that maintaining a healthy balance of gut microbes is crucial in regulating the immune system.

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JCI table of contents, 1 August 2003

Researchers found that 8 out of 20 commonly used NSAIDs can selectively lower Abeta42 levels in mice, with flurbiprofen showing the most promise. Additionally, studies revealed increased T cell reactivity to Abeta protein in older humans and patients with Alzheimer's disease, which could inform the design of future vaccines.

Is there a way to derail the children's 'Allergy March'?

Early detection and treatment of allergies can prevent serious complications and modify the progression of pediatric allergies. A specific IgE blood test can accurately diagnose atopy and guide treatment, including avoidance therapy and medication.

'Man's best friend' may be even better

Researchers have developed a canine model of nasal congestion and allergic rhinitis that closely resembles human conditions. The study found that histamine-induced nasal congestion in dogs was alleviated by α-adrenergic agonists, paving the way for testing new treatments.

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Two major food allergy firsts in North America

A new study reveals that peanut allergies are on the rise in Quebec, affecting approximately 1.5% of Montreal schoolchildren, compared to previous estimates of 0.5%. The Association québécoise des allergies alimentaires has also launched a certification program for allergen-free food products.

People with food allergies should not only be careful about what they eat

A severe allergic anaphylactic reaction was triggered in a woman with shellfish allergy after kissing her boyfriend, who had eaten shrimp hours earlier. The incident highlights the importance of counseling patients to avoid exposure to food allergens through all potential routes, including kissing and touching.

Experimental therapy stops allergic reactions in mice

A new experimental approach has been developed to treat allergic diseases, with scientists creating a genetically engineered molecule called GE2 that connects two receptors on key immune system cells. The molecule short-circuits allergic reactions, including asthma and anaphylaxis, by cross-linking receptor molecules.

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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

American Thoracic Society Journal news tips for April (first issue)

Two new studies found a relationship between high cat allergen concentrations in the home and increased asthma symptoms among sensitized women. Researchers also discovered common delays in TB diagnosis and treatment, as well as abnormal pulmonary function linked to bacterial infection in cystic fibrosis patients.

Potential allergy vaccine boosts hope for sufferers

Researchers at the University of Melbourne have developed a potential allergy vaccine using a modified rye grass protein that reduces allergenic response while boosting immune system. The vaccine, delivered in its pure form, may significantly reduce risk of anaphylactic shock and increase immunotherapy efficacy.

American Thoracic Society Journal news tips for February (first issue)

A new study found that caregivers with higher perceived stress levels had infants who experienced more wheezing episodes during the first 14 months of life. Additionally, exposure to German cockroach allergen was associated with increased risk of asthma attacks in susceptible children. Researchers also developed a molecular model of th...

Is there a link between alcohol and allergies?

Research found that regular alcohol intake higher than 70 grams per week is associated with increased total serum IgE levels. Moderate drinking may also lead to abnormal immune responses, affecting the control of the immune system's response to allergens.

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Researcher uncovers allergy/reflux link

A new study establishes a link between gastroesophageal reflux and allergies, including environmental allergens like pollens and molds. The discovery could lead to new treatments for children with eosinophilic esophagitis and adults with refractory reflux.

National Jewish, EPA put HEPA filters, air purifiers to the test

A National Jewish Medical and Research Center study, funded by the EPA, investigates the effectiveness of HEPA filters and electrostatic air filtration systems in removing allergens and irritants from homes of children with asthma. The study aims to determine if these interventions can help lower asthma severity in some children.

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Updated Asthma Guidelines Released

The new report updates asthma clinical practice guidelines with a focus on early use of anti-inflammatory medication, personalized treatment approaches, and reduced exposure to environmental allergens. The guidelines also include practical tools for physicians and expanded information about identifying specific allergens for each patient.

Allergy Shots Not Helpful For Many Children With Asthma And Allergy

A new study of 121 children aged 5-14 found that allergy shots had no significant benefits for patients whose asthma symptoms are controlled with medication. However, shots may be useful in certain groups, such as those with irregular medication use or difficulty avoiding allergens.

Race Plus Roaches: A Breathtaking Link

Research from Johns Hopkins Children's Center reveals that African-American children are 16.4 times more likely than Caucasian children to be sensitive to cockroach allergens, highlighting the link between race and asthma. The study also found that poor children and those from urban areas are more susceptible to roach infestation.