Articles tagged with Allergens
Researchers at McMaster University have successfully tested an antibody that can improve the quality of life for individuals with asthma by relieving inflammation in the lungs. The study found that blocking a specific protein in the lungs with an antibody alleviates baseline inflammation and provides resistance to allergens.
A nationwide study found that allergy prevalence is consistent across the US, with regional variations in specific types of allergies. Children under 5 in southern states showed a higher prevalence of allergies to dust mites and cockroaches.
A recent study suggests that exposure to dust from homes with dogs can alter the immune response to allergens, reducing allergic inflammation. The researchers found that mice fed dog-associated dust were protected against airway inflammation triggered by cockroach allergen and respiratory syncytial virus.
Studies by Helmholtz Centre for Environmental Research and University of Leipzig reveal species-specific allergens in Nile perch and shellfish, potentially allowing diagnosis and treatment tailored to individual allergies. Researchers identify parvalbumin as a common allergen, but also discover new proteins with low allergenic potential.
Researchers at the University of Notre Dame have made progress toward a treatment for dangerous allergies by designing a special molecule that can out-compete allergens in their race to attach to mast cell receptors. The team has demonstrated the effectiveness of their inhibitor molecule on allergic reactions using animal models.
The Integrated Approaches to Food Allergen and Allergy Risk Management (iFAAM) project will develop a standardized management process for companies involved in food manufacturing. New risk models will predict who is likely to suffer severe reactions, while tools to measure allergens will support efficient labeling and monitoring.
Babies born by C-section are five times more likely to develop allergies when exposed to common allergens. The study suggests that early childhood exposure to microorganisms affects the immune system's development and onset of allergies.
A study by Henry Ford Hospital found that African-American children are more likely to develop food allergies than Caucasian children, particularly those with an allergic parent. The research suggests a possible genetic link, but further investigation is needed.
A new device called the SXC ESP was created by Washington University engineers to better protect human lungs from allergens and airborne viruses. The device uses soft X-ray irradiation to capture particles, making it more effective than traditional air cleaners in removing biological agents from the air.
New research reveals that exposure to air pollution and cockroach allergen early in life can increase the risk of developing an asthma-related cockroach allergy by age 7. Children with a common mutation in the GSTM gene are especially vulnerable to this increased risk.
A new soft x-ray electrostatic precipitator device effectively captures and kills airborne pathogenic bacteria, viruses, ultrafine particles, and allergens. It has multiple potential applications, including indoor air purification and protection of vulnerable populations.
Researchers at UCLA have created a lightweight device called the iTube that attaches to a cell phone to detect allergens in food samples. The iTube uses the cell phone's camera and a smart application to run a test with high sensitivity, similar to laboratory tests.
Researchers are developing new medications and oral immunotherapy to treat food allergies, such as egg and peanut allergies. These treatments show promise in reducing emergency room visits and healthcare costs associated with food allergies.
Researchers discovered a strong correlation between pollen count and allergen release, but found significant variations in grass pollens across Europe. The study suggests measuring allergens may be more useful than forecasting pollen counts for allergy sufferers, offering new hope for treatment.
A new vaccine developed by Inserm researchers reduces both hypersensitivity to allergens and inflammatory response in asthmatic mice. The vaccine is based on DNA sequences of the allergenic substance Derf1 and has shown promising results in animal studies.
Scientists at The University of Nottingham have identified a new molecule DC-SIGN that plays a role in damping down the body's allergic response to house dust mites. This discovery could pave the way for developing new therapies or treatments for preventing allergies.
A new mouse model has been developed to study allergy to fenugreek, a common ingredient in Asian dishes. The model can also be used to understand suspected cross-reactivity with peanuts and other legumes, which may pose a special problem for food-allergic people.
Scientists at La Jolla Institute identify histamine releasing factor molecule as a promising target for developing new treatments for asthma and allergies. The discovery provides new insights on the role of HRF in promoting asthma and some allergies, including its receptor.
A simple device that filters out airborne asthma triggers during sleep can significantly improve quality of life and reduce symptoms of atopic asthma. The study found a 14-15% difference in quality of life scores between those using the device and those with a dummy device.
Researchers at University of Notre Dame engineer a new way to inhibit allergic reactions by introducing a special molecule that outcompetes allergens for mast cells. This approach prevents allergic reactions from occurring in the first place without suppressing the entire immune system.
A study published in Thorax journal found that sensory nerves detect allergens and trigger a 'late asthmatic response' several hours after exposure. Researchers discovered that anticholinergic drugs like tiotropium could alleviate symptoms, offering new potential treatments for asthma patients.
Researchers analyzed dust samples from 173 homes with a dog to evaluate hypoallergenic breeds. They found no significant differences in allergen levels between hypoallergenic and non-hypoallergenic dogs.
Research found higher levels of cockroach allergens and increased sensitization among children living on NYC blocks with high asthma rates. Cockroach exposure was associated with a higher risk of asthma, highlighting the relevance of urban allergen exposure to public health.
Researchers found that skin contact with food allergens can lead to the reprogramming of gut-homing T cells into skin-homing T cells, exacerbating atopic dermatitis. This discovery has important implications for preventing and treating atopic dermatitis in patients with food allergies.
A new study reveals apparent gaps in restaurant staff's knowledge of food allergy, with common allergens not separated from other foods in one out of three kitchens. Despite lacking formal training, 80% of respondents reported confidence in providing safe meals for food-allergic customers.
A new anti-asthma medication has been found to nearly eliminate seasonal asthma attacks in children and young adults with allergic asthma. Researchers found that the treatment improved asthma control, reduced symptoms by 25%, and decreased asthma attacks by 30%.
Researchers at the University of Nottingham have discovered a cell component that plays a key role in triggering allergic responses to cat dander. The finding could lead to the development of new treatments for allergies and asthma.
A Finnish study found that children born in spring are more likely to develop food allergies due to sensitization during fetal development. Research suggests a peak in birch and alder pollen levels in April-May may contribute to this association.
Researchers at Cincinnati Children's Hospital Medical Center have identified interleukin-17A as the chief culprit behind severe asthma-like symptoms in mice. The study found that blocking IL-17A production or targeting the complement factor 3 pathway can reduce airway hyper-responsiveness and inflammation.
Researchers found that people with allergic asthma are more susceptible to respiratory viruses like the flu due to impaired immune response. Elevated IgE levels in dendritic cells may interfere with antiviral proteins, worsening asthma symptoms.
A new technology developed by MIT chemical engineer Christopher Love can analyze individual immune cells taken from patients, allowing for precise measurement of the cells' response to allergens. This approach enables faster and more reliable food allergy diagnoses than current tests.
The European Commission's Joint Research Centre has released a new guidance document that harmonizes validated testing methods for food allergens, increasing consumer protection and facilitating international trade. This development is crucial for labelling of food products and avoiding allergic reactions.
A study by Spanish chemists has detected up to 15 fragrance allergens in baby bathwater, including benzyl salicylate and hydroxycitronellal. The researchers found extremely high concentrations of these substances, exceeding 100ppm, raising concerns about their impact on children's health.
Using integrated pest management (IPM) can significantly reduce cockroach populations and associated allergen concentrations in schools. A new study found that IPM is more effective than conventional methods in reducing asthma incidences among inner-city children.
Researchers found that allergens can bind to and travel through the epithelium of allergic patients but not healthy subjects. This transport mechanism is crucial for the development of allergic reactions.
A study found that airborne fungal groups Cladosporium and Mycelia sterilia are more common in urban areas with high vehicular traffic, contributing to the region's high asthma incidence. The research suggests a link between environmental triggers and genetic susceptibility, shedding light on the complex factors driving the epidemic.
A study comparing results of allergy patch tests between children and adults found that both groups reacted to various allergens at approximately the same rate. However, children were more likely to react to nickel, cobalt, thimerosal, and lanolin, while adults were more likely to react to neomycin, fragrance mix, M. pereirae, and quat...
Researchers found environmental pollutants can cause 'environmental laryngitis' through animal models, citing exposure to dust mites and air pollution as triggers for the condition. This finding is significant given recent reports on diminishing air quality and increased unhealthy levels of ozone and particle pollution.
Researchers at the Salk Institute have discovered that a protein called IKK2 plays a crucial role in regulating de-granulation, a process involved in allergic reactions. By targeting IKK2, scientists hope to develop acute inhibitors for treating allergies and potentially other diseases.
Recent studies suggest that specific immunotherapy can be an effective treatment for allergies, reducing symptoms and adverse reactions. The Institute also found that certain measures, such as quitting smoking and taking probiotics during pregnancy, may help prevent allergies in children.
A study found that mothers' prenatal stress may increase their babies' sensitivity to allergen exposure and future asthma risk. High levels of IgE expression in cord blood were observed among infants whose mothers experienced higher levels of stress, even with low dust mite exposure.
A University of Pittsburgh School Medicine study identified a key molecule, c-Kit, that plays a central role in the allergic response. Targeting this element could lead to more effective drugs for treating asthma and allergies.
Researchers at Ohio State University identified 14 types of mold on and around Madagascar hissing cockroaches, including molds associated with allergies. Handling the insects may trigger allergic responses in sensitive individuals if proper cleaning and care are not taken.
Researchers at Penn State University have discovered that lipid molecules in cell membranes play a key role in triggering allergic reactions. The team used advanced imaging techniques to show how cholesterol-rich lipid domains associate with IgE antibodies and their receptors, leading to histamine release and allergic symptoms.
A new national survey found that elevated indoor allergen levels are associated with asthma symptoms in allergic individuals, particularly those with allergies. Regular household cleaning and reducing exposure to pets and pests can help alleviate symptoms.
A major five-year study will analyze 32 common allergen sources, identifying T cell responses and potential epitope-based therapies. The project may lead to revolutionary new approaches for treating allergies, potentially reducing the need for lengthy desensitization treatments.
Researchers found that pitrakinra significantly reduced asthma symptoms in patients, with a maximum decrease of 17.1% in forced expiratory volume (FEV1) compared to placebo groups. The study suggests that pitrakinra may be an effective treatment option for asthma, offering promising results.
New research from Norwich BioScience Institutes and Medical University of Vienna found that only animal food proteins less than 54% identical to human equivalent can become allergenic. The study identified three protein families, including tropomyosins, EF-hand proteins, and caseins, which are responsible for most animal food allergies.
The study found that over 50% of asthma cases are linked to allergies, with cat allergy being the leading cause. Atopy, a condition resulting from gene-environment interactions, is measured by skin tests and was associated with nearly 57% of asthma cases.
Researchers found that even moderate exposure to cat allergen resulted in significantly greater responsiveness among individuals with any sensitization. The study suggests that reduced exposure to cats may be beneficial for allergic individuals, regardless of their specific allergies.
Washing laundry in hot water (140°F) kills all house dust mites, while washing in warm water only removes 6.5% of them. Rinsing with cold water after low-temperature wash is also effective.
A study published in Journal of Allergy and Clinical Immunology found that exposure to cat allergens at home increases the frequency of allergic sensitization in young children. The study analyzed data from over 1,000 children born between 1997 and 1999 and found that even brief contact with cat hair can lead to sensitization.
Researchers found that different parts of the brain are activated depending on the cause of itching, with allergen-induced itches activating the supplementary motor and posterior parietal areas. Histamine-induced itches, on the other hand, activate a smaller area of the brain, suggesting a compulsion to scratch in those cases.
Zaditor offers up to 12 hours of continuous itch relief with one drop, a significant improvement over most OTC products that only provide 3-4 hours of short-term relief. The medication is safe for use in children as young as three and does not contain decongestants that can cause rebound redness.
A new study by Cincinnati researchers found that children of allergy sufferers are more likely to develop allergic sensitization at a younger age. The study suggests reevaluating skin testing practices for airborne allergens in infants under 4 or 5 years old.
A new study found that an investigational therapy reduced allergy symptoms in adults for at least a year after just six injections of the major ragweed allergen, Amb a 1, coupled to a unique DNA sequence. The therapy showed promise in reducing symptoms and improving quality-of-life scores compared to standard immunotherapy.
A six-week experimental allergy treatment has relieved hay fever symptoms for at least two years in a clinical trial. The novel DNA-based drug AIC blocks the seasonal rise in ragweed-specific IgE and reduces IL-4, hinting at successful immune system reprogramming.
A study published in The Lancet found that children with persistent wheezing and allergies are at higher risk of developing lung function loss and asthma. Exposure to high levels of allergens also contributes to the development of asthma.
A recent UK study found that one third of food packaging tested contained latex, with transferable amounts causing severe reactions. The lack of labelling poses a significant risk to individuals with natural rubber latex allergies, who can be exposed to deadly levels of the allergen.
Researchers are developing drugs called Allergen Delivery Inhibitors (ADIs) to stop allergens from entering the body. These ADIs promise to be significantly better than current treatments, which only ease symptoms rather than preventing allergic reactions.