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ASHG honors Mary-Claire King with ASHG Advocacy Award

Mary-Claire King has been recognized by ASHG for her tireless advocacy on using genetics to help people and families worldwide. Her lab has helped reunite 130 families through mtDNA sequencing, and her work with the UN Forensic Anthropology Team has identified victims of extra-judicial execution.

New perspective on tumor genome evolution

Researchers developed a method to detect genes under selection and found essential cancer genes and immune-exposed protein regions under significant negative selection. This challenges the exclusive role of positive selection in cancer evolution.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

ASHG honors Andrew Adey with early-career award

The American Society of Human Genetics (ASHG) recognizes Dr. Andrew Adey's contributions to cancer development and progression research. His novel single-cell technologies are being used worldwide to understand epigenetics and disease models.

Ancient dog cancer still around today after 10,000 years

Researchers found a cancerous tumor that has been present in modern American dogs for thousands of years, tracing it back to ancient dog populations that arrived with early humans. The study suggests catastrophic events may have led to the sudden disappearance of these early canines.

New tools used to identify childhood cancer genes

A new computational strategy using Bayesian analysis and CRISPR/Cas9 screening technology has identified 29 genetic changes contributing to rhabdomyosarcoma, a common childhood cancer. The study suggests potential treatments for the disease and provides a general approach for identifying oncogenic drivers in other cancers.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Researchers map the genome of testicular cancer

A collaborative effort has discovered molecular features of testicular germ cell cancers, identifying potential mutations and other molecular changes. The study found signs of duplicated DNA and defects in DNA methylation, which could inform future efforts to improve treatment decisions and help monitor patients for cancer recurrence.

Davis Instruments Vantage Pro2 Weather Station

Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

New insights into the origins of mutations in cancer

Researchers used human and C. elegans data to understand the mutational causes of cancer, finding a resemblance between nematode worms and human cancer genomes. They discovered DNA mismatch repair deficiencies in both species, providing insights into the causes of cancer and potential treatment avenues.

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Even DNA that doesn't encode genes can drive cancer

Researchers identified nearly 200 mutations in non-coding DNA that play a functional role in cancer, providing potential molecularly targeted therapeutics. These mutations could represent new targets for cancer drugs and may help explain the diversity of genetic mutations in tumors.

Surprising discovery provides insights into aggressive endometrial cancers

Research at Huntsman Cancer Institute found that estrogen and glucocorticoid receptors work together to promote more aggressive endometrial cancers. The study suggests that corticosteroids, a stress hormone, can make the uterine lining stop growing but may also contribute to tumor growth when combined with high estrogen levels.

Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Acoustic nanomotors

Scientists successfully use ultrasound to propel gold nanowires carrying the Cas9-sgRNA complex across cell membranes, enabling targeted gene knockout. The system is simple and requires minimal payload, making it a promising therapeutic approach for cancer treatment.

Matchmaking for cancer care

A team of computer scientists has developed a new system to rapidly determine which cancer drugs are likely to work best given a patient's genetic markers. eGARD, the first publicly available system of its kind, can match genetic signatures with outcomes with 95 percent precision.

Study provides first systematic survey of metabolites across tumor types

A comprehensive dataset of cancer cell metabolites has been compiled, showing consistent increases or decreases in certain metabolites across multiple tumor types. The study's findings offer insights into the metabolic programming between normal and cancer cells, with potential applications for novel therapies.

Discovery may advance neural stem cell treatments for brain disorders

Researchers at Sanford Burnham Prebys Medical Discovery Institute have made a groundbreaking discovery that may advance neural stem cell treatments for brain disorders. The study reveals how an mRNA modification impacts the life of neural stem cells, and how it regulates histone modifications to maintain their self-renewal.

DJI Air 3 (RC-N2)

DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

California awards UCSC Precision Medicine Funds for childhood cancer research

The UC Santa Cruz Genomics Institute's Treehouse Childhood Cancer Initiative has received a $500,000 grant to conduct a 24-month registry study evaluating the effectiveness of comparative RNA-seq analysis in pediatric cancer treatment. The project aims to assess the impact on clinical decision-making and patient outcomes.

Uncovering molecular targets for childhood cancer therapeutics

Researchers found that nearly half of neuroblastoma samples had gene loss or imbalance in DNA damage response-associated molecules located on chromosome 11. PARP inhibitors, commonly used for ovarian cancer treatment, showed promise as a potential therapeutic approach for targeting childhood cancer.

Research reveals how cells rebuild after mitosis

New research from the University of Bristol demonstrates that cells use F-actin to reshape their nucleus and reorganise their genome after cell division. This process is essential for life, but was poorly understood until now.

Columbia researcher develops a molecular taxonomy for hair disorders

A research team from Columbia University has developed a molecular taxonomy for hair disorders, which will help diagnose diseases affecting the hair follicles. The taxonomy was created by analyzing more than three million data points and identified nearly 5,000 biological terms shared by groups of hair genes.

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

UVA aims to help patients with cancer make complex care decisions

Researchers at UVA Cancer Center are developing a tool to assist patients in making treatment decisions based on their tumor's genomic information. The tool aims to provide personalized comparisons of treatment options, incorporating factors like age, personal priorities, and health conditions.

The genome of Leishmania reveals how this parasite adapts to environmental changes

Scientists demonstrate that Leishmania adaptation results from frequent and reversible chromosomal amplifications, which enables the parasite to maintain genetic diversity while selecting for new alleles. This study has important consequences for understanding human Leishmania infection and identifying parasite drug resistance mechanisms.

Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.

Improved method of engineering T-cells to attack cancer

Researchers at Cardiff University have developed a new method of engineering T-cells to attack cancer using CRISPR genome editing. This breakthrough enhances the T-cells' ability to recognize specific cancer cells and destroy them, offering new hope in the fight against various types of cancers.

'Precision medicine' for cancer patients may not always be so precise

A new study found that precision medicine for oncology is less precise for people of Latin American, African, and Asian ancestry due to the lack of diverse genetic population data. A computational tool called LumosVar was created to help researchers sort out potentially inaccurate results and improve precision medicine.

Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

3-D packaging of DNA regulates cell identity

A Penn study suggests that DNA 3D packaging controls which genes are available for activation, influencing cell differentiation. The researchers found that tethering DNA to the nuclear periphery with an epigenetic enzyme contributes to a cell becoming a certain type.

Garmin GPSMAP 67i with inReach

Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.

Association for Molecular Pathology announces 2017 award recipients

The Association for Molecular Pathology (AMP) has awarded prestigious honors to Drs. Andrew P. Feinberg, Gregory J. Tsongalis, and Alexis B. Carter for their outstanding contributions to the field of molecular diagnostics. AMP President Federico A. Monzon praised the award recipients for their decades of service to the society.

GoPro HERO13 Black

GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.

On the other hand, the immune system can also cause cancer

A University of Colorado Cancer Center paper describes a mechanism linking viral infection and cancer caused by APOBEC3 enzymes, which are part of the immune system's response to viruses. The research suggests that targeting these enzymes could prevent or treat certain types of cancer.

Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Searching for the 'signature' causes of BRCAness in breast cancer

A study has identified a genetic signature linked to defects in the DNA damage repair-genes BRCA1 and BRCA2 in breast cancer. The researchers found that this signature is not exclusive to BRCA mutations but also indicates other ways of deactivating the DNA repair mechanism, offering new insights into breast cancer treatment decisions.

Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.