Articles tagged with Cancer Patients
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A systematic overview of 22 trials found that preoperative radiotherapy reduces local recurrences by half compared to surgery alone, with a third reduction in postoperative radiotherapy. Fewer patients who received preoperative radiotherapy died from rectal cancer, but early deaths increased.
A study published in General Hospital Psychiatry found that guided imagery relaxation with body relaxation reduced psychological distress in cancer patients. The benefit was most pronounced in those with higher levels of distress before the intervention.
A study published in The Journal of Nuclear Medicine found that FDG PET detected recurrent thyroid cancer 50% more often than conventional imaging, leading to changes in clinical management for almost 80% of patients. The PET scan identified additional tumor sites and distant metastases, improving patient outcomes.
A study found that patients with severe psoriasis who use ciclosporin are at a significantly higher risk of developing squamous cell cancer. The risk is particularly high for those using the medication long-term or for extended periods, highlighting the need for careful assessment of its safety.
A computerized tool called Prostogram offers about 66% accuracy in predicting five-year prognosis following brachytherapy treatment for early-stage prostate cancer. The nomogram is based on individual factors such as PSA levels, Gleason score, and disease stage.
Despite physical and emotional struggles, many cancer patients report good quality of life -- often comparable to the general public or physicians. The study found that quality of life had improved or remained the same for most participants, with radiation therapy being associated with a negative effect.
A large population-based study in Nordic countries found no increased cancer risk for siblings of children with common non-inheritable cancers. Siblings younger than 10 years were at higher risk, but this decreased with age. The study suggests that childhood cancer is not a predictor of increased cancer risk in siblings.
A recent UCSF study found that fine needle biopsy (FNAB) accuracy can be significantly improved with formally trained physicians. The researchers analyzed 927 women's medical histories and tissue samples, finding that less-well-trained practitioners were more likely to miss cancers due to errors in sampling.
Research studies found that low MBL concentrations are associated with prolonged fever and infection in cancer patients undergoing chemotherapy. MBL infusions may represent a new therapeutic approach to reduce illness and death for these patients.
A Swedish study published in The Lancet found no association between antihypertensive drug treatments and an increased risk of cancer. The study analyzed 6600 patients with hypertension, randomly assigning them to three treatment strategies, and found no significant difference in cancer incidence between groups.
PS-341, a proteasome inhibitor, has shown promising results in treating multiple myeloma and non-Hodgkin's lymphoma. The Phase I clinical trial found one complete response and several partial responses among patients, indicating the drug's potential as a treatment option.
The new imaging device provides a larger bore diameter, allowing patients with large or obese bodies to receive scans in treatment position. This enables oncologists to obtain more accurate views of the patient's body dimensions and calculate radiation doses for cancer treatment.
The University of Pittsburgh Cancer Institute has received a $12 million grant to examine innovative detection and treatment strategies for patients with early- to late-stage lung cancer. The grant will focus on improving survival outcomes and quality of life through the use of newest diagnostic tools and latest treatments.
A new study published in Psycho-Oncology found that people with advanced cancer are more willing to consider toxic chemotherapy regimens, even if they offer only minimal benefits. Cancer patients generally accepted both milder and riskier treatments, unlike healthy individuals and healthcare professionals.
A new study led by Thomas Jefferson University researchers found that once-a-day injections of the blood thinner enoxaparin sodium are just as safe and effective as twice-daily treatments in treating blood clots. This finding has significant implications for medical cost savings.
A new partial voice box resection procedure shows excellent local control and significant improvement in quality of life for patients with intermediate to advanced stage larynx cancers. This approach can provide a less drastic treatment option, reducing hardship on patients.
A Phase I study found that a dendritic cell vaccine extended median survival for patients with GBM by 455 days, compared to 257 days in the control group. The treatment elicited systemic immune responses and directed T-cells to the tumor site.
Researchers found that women who exercised on their own had better aerobic results than those in supervised groups. Exercise improved physical functioning by 5.7 points, with significant weight loss among tamoxifen users.
The article highlights the need to shift from aggressive treatment to palliative care in hospitals and healthcare facilities, improving quality of life for dying patients. Strategies can be implemented to reduce suffering by involving a multidimensional approach to care.
A study found that PET scans are more accurate than traditional diagnostic techniques in determining how far lung cancer has spread. PET scans revealed cancer in 27 patients that had spread farther than thought, sparing them from futile attempts at aggressive therapy.
Researchers are applying their radar technology to detect missiles to a FDA-approved Phase II clinical trial for treating breast cancer. The treatment involves heated microwave radiation that kills cancer cells without burning the skin.
A Mayo Clinic study finds that less radical surgery for kidney cancer is equally effective to radical alternative and less likely to cause failure in the second kidney. Long-term survival rates between the two procedures were identical, but patients undergoing less radical surgery had a lower risk of developing renal failure.
A study by Dr. William S. Breitbart found that clinical depression and hopelessness are key factors contributing to a patient's desire to die, even more important than physical pain. The study suggests that addressing psychological needs is crucial in minimizing the desire for death.
A cost-effectiveness study finds radiofrequency ablation effective in treating supraventricular tachycardia, improving quality of life and reducing hospital visits. However, the online availability of hydrazine sulfate, touted as a cancer treatment with few side effects, has raised safety concerns after a fatal case report.
Phase II studies indicate that Mylovenge causes regression or stabilization in over 30% of patients with multiple myeloma and amyloidosis, with some benefits lasting up to 18 months. The vaccine stimulates the immune system to recognize and destroy cancer cells.
A new study by University of North Carolina at Chapel Hill researchers shows that watching a videotape explaining colon cancer procedures can increase screening rates by at least 15%. This could lead to significant reductions in deaths from colorectal cancer, with over 47,000 Americans dying annually.
Thalidomide demonstrates potential activity in multiple myeloma, primary amyloidosis, metastatic colorectal cancer, and acute myeloid leukemia, with notable improvements in patient survival rates and side effects observed.
University of Florida surgeons have improved a bladder removal technique, reducing complications and improving patient outcomes for those with severe bladder problems. The new method minimizes blood loss and is well-tolerated by patients, making it an ideal approach for those too ill to undergo standard surgery.
MARstem demonstrates potential as a multilineage hematopoietic therapy to treat or prevent pancytopenia following chemotherapy in breast cancer patients. The study's results show excellent safety and preliminary efficacy, suggesting MARstem may improve debilitating side effects of cancer treatment.
Early results from 19 patients treated in the Boston clinical trial show that Endostatin is safe and well-tolerated in high doses without any evidence of toxicity. Extended periods of stable disease and minor responses have been demonstrated, but further study is needed to determine its long-term effectiveness.
Researchers developed a new FISH-based method for detecting recurring bladder cancer, showing improved accuracy compared to urine cytology. The test detected high-grade cancers with over 95% accuracy and recurrence up to three months earlier than traditional methods.
A new radiation treatment technique targets head and neck tumors while sparing salivary glands, enabling patients to function more normally. Patients who received intensity-modulated radiation therapy (IMRT) experienced improved saliva flow and quality of life compared to conventional radiation therapies.
A definitive study led by John Kirkwood at the University of Pittsburgh Cancer Institute found that high-dose interferon alfa 2b extends both overall survival and relapse-free survival in surgically treated high-risk melanoma patients. This regimen significantly outperforms a comparison vaccine, GMK, in terms of survival impact.
Phase I clinical trials show CCI-779's potential as a cancer treatment, inhibiting tumor growth with minimal side effects. The drug targets the mTOR pathway, which may selectively arrest the development of certain cancer cells.
A study by Texas A&M University researcher Dr. Jeff Guidry reveals that non-treatment problems hinder successful cancer treatment and cure for patients in rural areas. The study shows that barriers to overcoming cancer include lack of transportation, proper information, access to treatment, and a support system.
Researchers at UCSF Comprehensive Cancer Center are testing an immunotherapy treatment that involves collecting stem cells from a patient's sibling to attack the cancer. The trial aims to confirm previous NIH study results and explore its potential in treating solid cancers, including prostate and melanoma.
A new nomogram developed at Memorial Sloan-Kettering Cancer Center predicts outcomes based on disease factors such as stage, PSA level, and radiation dosage. The tool demonstrates improved accuracy in estimating treatment efficacy compared to existing models.
A recent study conducted at Indiana University Medical Center found that high-dose chemotherapy followed by stem-cell transplantation can achieve a durable remission in approximately 50% of patients with recurrent testicular cancer. The overall cure rate for these patients is now estimated to be around 85 percent.
A novel liposuction treatment has been developed to treat chronic lymphoedema in breast cancer patients, reducing arm swelling by up to 98% and improving mobility and pain levels. The treatment involves removing fatty tissue and accumulated lymph via small incisions along the arm.
Researchers at Memorial Sloan-Kettering Cancer Center developed a new combination therapy of irinotecan, fluorouracil, and leucovorin that nearly doubled the tumor response rate and improved overall survival for patients with metastatic colorectal cancer. The study showed significant benefits with no increased incidence of serious side...
Lymphoedema is a chronic condition resulting from breast cancer surgery and radiotherapy, characterized by swelling, pain, and disability. Early diagnosis and proper treatment can help alleviate symptoms, but increased awareness and education for healthcare professionals are crucial to prevent disastrous consequences.
Adjuvant treatments with radiotherapy, chemotherapy, and hormone treatment tamoxifen can prevent late recurrences in breast cancer patients. The new findings show a significant decrease in deaths from breast cancer in middle-aged women, with a 30% fall over the past decade in the UK.
A Phase I/II study found substantial and occasional complete regression of widespread tumors in patients with treatment-resistant metastatic renal cell carcinoma treated with blood stem cell transplants. Three patients achieved total regression, while seven showed partial regression of disease.
The 2nd European Breast Cancer Conference will bring together over 3000 healthcare professionals, scientists, and patient advocates to share new developments in breast cancer research, treatment, and care. Distinguished international speakers will address key issues about the future of breast cancer research, treatment, and care.
A study found that six months of care for patients in phase II clinical trials costs $57,542, similar to $63,721 for those receiving standard treatment. This research suggests insurers can improve healthcare without financial risk.
A new laser treatment being tested at Rush University Medical Center has shown promise in eliminating the need for surgery in women with small breast cancers. The procedure uses a laser delivered through a needle to destroy tumors detected by mammography, resulting in no complications and minimal pain.
Researchers found that patients with localized prostate cancer who received higher doses of radiation lived longer and had better local control of their cancer. The study, published in the Journal of Clinical Oncology, examined data from 1560 patients treated between 1975 and 1995.
Patients with dementia often receive inadequate medical care due to a lack of data on the safety and efficacy of treatments. Guidelines need to consider a patient's ability to comprehend, remember, and follow directions, as well as their caregiver's capacity to listen and act.
A Phase III study found that a combination of histamine dihydrochloride and lower doses of interleukin-2 improved overall survival, increased survival rates at 12, 18, and 24 months, and reduced time-to-disease-progression compared to IL-2 alone. The treatment was well-tolerated and had substantially less toxicity.
Dr. Yoav Horn founded the West Bank Cancer Program in 1978, helping to establish two oncology treatment centers and train Palestinian physicians. The program improved early cancer treatment and saved lives, according to data from a computerized registry of over 7,000 patient records.
The study confirms that M-Vax increases the survival rate of patients with advanced Stage III melanoma, even after disease recurrence. Patients who developed an immune response against their melanoma had a far better outcome, with a five-year survival rate of 65%.
A study found that 40% of cancer patients use unconventional medical therapies and do not report this information unless specifically asked by their physicians. These therapies, such as mega-doses of vitamins and herbal supplements, can potentially interfere with radiation treatment.
The data from an ongoing Phase 1/2 trial of O-Vax in patients with advanced ovarian cancer indicates that the vaccine induces a positive immunological response, as measured by a delayed type hypersensitivity test. Favorable clinical responses were also observed, including complete regression of tumors and normalization of CA-125 levels.
A new study shows Bexxar produced tumor shrinkage in 97% of patients with advanced-stage, low-grade non-Hodgkins lymphoma. Most patients achieved complete remission, with no sign of cancer, and molecular remissions lasting up to three years.
The company presented Phase II data of tgDCC-E1A, a lead cancer therapy, which showed a 45% objective response rate in patients with recurrent head and neck squamous cell carcinoma. Preclinical studies also demonstrated the ability of E1A to sensitize tumors to radiation and chemotherapy.
A Phase III trial shows long-term hormone suppression can control recurrence and improve survival in prostate cancer patients. The treatment significantly reduces disease-free survival, local progression, and freedom from distant metastasis.
A Phase II trial found a 40% response rate with low-dose anti-VEGF combination therapy, compared to 24% for high-dose and 17% for chemotherapy alone. Median survival increased by 2 months with the low-dose treatment.
A study published at ASCO suggests that treating cancer patients on clinical trials is not more expensive than standard treatment. The research found average charges of $57,542 for trial patients and $63,721 for control patients, highlighting the potential for increased access to high-quality care.
Researchers have reported promising results from a Phase I-II trial of an ovarian cancer vaccine made from patient's own cancer cells. Eight of 10 patients showed immunological response, with one experiencing complete tumor disappearance and CA125 levels normalization.
A custom-made vaccine created from a patient's own cancer tumor cells has proven effective in prolonging the survival of patients with malignant melanoma. The vaccine resulted in a 47% five-year survival rate among 214 patients with disease spread, outperforming standard treatment.