Articles tagged with Cancer Patients
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A decision aid called Decision Board improved patients' understanding of their disease, risk of recurrence, and treatment options. Women who used the board were more satisfied with decision making and preferred a more active role in their care.
A study of 1,383 cancer patients found that uninsured patients paid more for healthcare services but received significantly fewer treatments and services compared to insured patients. The disparity was attributed to various factors, including age at diagnosis and insurance coverage by race and ethnicity.
Uninsured cancer patients receive far less health care, with higher out-of-pocket spending compared to privately insured patients. The study highlights disparities in healthcare coverage between Hispanic and non-Hispanic populations, with uninsured Hispanic patients facing significant barriers to care.
A new generation of medical treatment is being driven by proteomics, enabling early detection of cancer and personalized therapy. The technology uses multiple high-resolution serum proteomic patterns to detect disease, with 85% accuracy in diagnosis.
The National Cancer Research Institute (NCRI) has launched the National Cancer Tissue Resource to address the fragmented approach to collecting and using tumour samples for research. Key areas of study requiring large-scale sample collection include predicting outcomes, identifying inherited markers, genetic susceptibility to cancer.
A recent study found that genes determining breast density are associated with an increased risk of breast cancer. Additionally, researchers discovered a compound called YC-1 that slows tumor growth in mice by blocking angiogenesis, potentially leading to new cancer treatments.
Researchers at Dana-Farber Cancer Institute discover that a rare blood disorder HES is caused by a fusion of genes creating a cancer-causing gene, which can be inhibited by the imatinib drug. The study shows that patients with HES respond well to the treatment, offering new hope for this aggressive disease.
A new study finds Keppra alleviates severe nerve pain in cancer patients by reducing VAS scores to 0-3 within 3-14 days, with a significant decrease in opioid use. The medication was well-tolerated and showed potential therapeutic benefits for further investigation.
The study found that 50% of patients started taking dietary supplements, 40% made dietary changes, and 20% began new physical activities. Lifestyle changes were common among cancer patients up to two years after diagnosis and were often associated with improved health and well-being.
A study found that higher plasma folate levels were associated with lower risk of breast cancer, while higher plasma vitamin B6 levels increased breast cancer risk. Plasma vitamin B12 levels inversely associated with breast cancer risk among premenopausal women. Cystic fibrosis patients may have an increased risk of digestive tract can...
A Mayo Clinic phase II study of 42 patients with advanced androgen-independent prostate cancer found that green tea did not provide therapeutic benefit. The study showed no sustained decline in PSA levels, and high doses of green tea were associated with significant side effects.
A recent study found that over 90% of internet sites promoting floressence and amalaki raised red flags due to lack of scientific evidence, while only 23% of selenium sites with some research backing did. The researchers recommend using specific questions to identify questionable sites.
Researchers have identified a gene responsible for the spread of cancer in the body, which could lead to more targeted and less toxic treatment options. The study found that silencing this gene can halt the migration of cancer cells, reducing the risk of metastasis.
Researchers found that patients with xeroderma pigmentosum had lower DNA repair capacity than control subjects, increasing their risk for melanoma. A natural compound called deguelin may have potential as both a chemopreventive agent and a therapeutic agent against lung cancer.
A new phthalocyanine compound, Pc 4, targets cancerous cells preferentially, leaving healthy tissue alone. The treatment uses laser light to activate the drug, producing forms of oxygen that kill cancer cells and break down tumors.
In Nova Scotia, a 52% increase in out-of-hospital cancer deaths between 1992 and 1997 was observed. This trend poses challenges for the healthcare system, particularly palliative care.
A novel treatment approach combining surgery and intraperitoneal hyperthermic chemotherapy (IPHC) has shown significant promise in improving survival rates for patients with peritoneal carcinomatosis. The study found that selected patients may benefit from improved quality of life and extended survival.
Scientists at the University of North Carolina at Chapel Hill have discovered a new role for the BLM gene in repairing DNA breaks, which can lead to cancer. The study found that the BLM gene is essential for maintaining genome stability and preventing chromosome rearrangements similar to those seen in follicular lymphoma.
Researchers at Purdue University have discovered a single protein that sets the length of periods of activity and inactivity within cells, known as the biological clock. The discovery has significant implications for medicine, including minimizing jet lag and determining optimal cancer treatment timing.
Researchers have found a promising combination therapy that may significantly improve treatment outcomes for patients with advanced prostate cancer. In a phase II clinical trial, the combination of calcitriol and docetaxel showed a higher PSA response rate compared to docetaxel alone.
A study of 213 terminally-ill cancer patients found that only 7% expressed concern over losing dignity. The majority reported psychological distress and symptom distress instead. This highlights the need for dignity-conserving care in palliative care.
A survey of 1,120 cancer physicians reveals substantial differences in views about the purpose of clinical trials. Pediatric oncologists are more likely to enroll patients in trials for state-of-the-art treatment, while other specialties prioritize scientific advancement and future patient care.
A study by researchers at the H.Lee Moffitt Cancer Center has identified the ERCC1 gene as a potentially clinically useful independent marker for lung cancer. Patients with high levels of ERCC1 are more likely to survive after surgery and may benefit from platinum-based chemotherapy, while those with low levels have a poorer prognosis.
Researchers at UVA have identified a gene called RhoGDI2 that plays a crucial role in preventing the spread of cancer. The study found that replacing this gene in human metastatic cancer cells can suppress their ability to metastasize, suggesting new therapeutic options for treating metastatic disease.
A clinical trial led by Dr. Joseph Friedberg at Thomas Jefferson University Hospital is exploring the effectiveness of photodynamic therapy (PDT) on non-small cell lung cancer, with patients showing survival times between three and four times the usual six to nine months after surgery.
Researchers found that PC-SPES reduced the effectiveness of paclitaxel treatment in both androgen-sensitive and androgen-independent models of prostate carcinoma. Consumption of garlic, chives, and other allium vegetables may be associated with a reduced risk of prostate cancer.
The Mayo Clinic study shows RF ablation can effectively kill cancer cells causing bone pain, with 95% of patients experiencing significant pain relief. The procedure takes 30-60 minutes and alleviates pain by killing nerve endings and cancer tissue.
A new programme, GOALS, has been developed to help cancer patients discuss their condition with family, friends, and colleagues. The five-step protocol focuses on identifying the right place and moment for conversation, acknowledging emotions, and developing a strategy to open discussion.
A new information structure called Point of Information and Support (PIS) has been shown to reduce patients' anxiety and depression by providing personalized health information. The PIS comprises a library with booklets, videos, and essential information about cancer types and drugs.
Research by Dr Anne Chantal Braud and her team has shown that older women with breast cancer can tolerate powerful medication, contradicting initial expectations. The study examined the effects of surgery, radiotherapy, chemotherapy, and hormone therapy on 179 women over 70 years old.
A ESMO survey found that almost all oncologists (92%) believe dying patients should receive anti-tumor therapy alongside end-of-life care. However, less than half routinely coordinate patient care or collaborate with support teams.
A patient's view on clinical trials highlights the importance of thorough explanations, confidentiality, and compassionate communication. Sylvia Achin emphasizes that patients risk losing their priorities, relationships, and even support when faced with a life-threatening disease like cancer. Effective communication can help alleviate ...
Key findings from the ESMO Congress emphasize the need for better care and communication in cancer treatment. Patients must be informed and involved in their treatment decisions, while healthcare professionals should prioritize empathy and understanding. A European cancer patient coalition is proposed to amplify patients' voices.
A recent study suggests that cancer patients who have smoking-related cancers such as lung, head and neck or bladder cancer are more likely to quit smoking. These patients were also more likely to have made attempts to quit in the previous 12 months and had not received radiotherapy or surgery.
Professor Edzard Ernst urges oncologists to be open to alternative medicines, as desperation drives patients to try anything. He warns that some therapies can be dangerous and advises patients to consult with healthcare professionals before trying new treatments.
A study by Professor Lesley Fallowfield found that psychosocial discussions are often overlooked in cancer treatment consultations. Training can help doctors and nurses discuss personal and sexual issues comfortably and sensitively, improving patient outcomes.
The American Association for Cancer Research (AACR) is calling on the FDA to accelerate the development and approval of chemopreventive agents for precancerous cells. Emerging technologies have improved detection capabilities, but drug approvals remain limited due to concerns about treatment efficacy in high-risk populations.
Researchers at the University of Pittsburgh Medical Center have developed a gene therapy that significantly reduces bone cancer pain in mice. The therapy uses an inactivated herpes simplex virus to deliver the human gene for proenkaphalin, a naturally occurring painkilling peptide.
Recent cancer patient data reveals higher-than-expected five-year to twenty-year relative survival rates across various types of cancer. Period analysis shows more optimistic estimates compared to traditional cohort-based methods.
Researchers at Ohio State University Wexner Medical Center have been awarded a $9.5 million grant to study the innate immune system and develop new cancer therapies. The project will explore how targeted therapies can be more potent in the presence of certain agents, and will involve multiple clinical trials and laboratory projects.
Researchers highlight the importance of selecting an antiemetic with low potential for drug interactions in elderly cancer patients. Granisetron, a 5HT3 receptor antagonist, is considered a safe choice due to its low risk of cardiovascular toxicity and adverse interactions.
Leading oncology experts emphasize the need for additional research among elderly cancer patients with co-morbid conditions and those taking multiple medications. They advocate for equal access to treatment options as younger patients, highlighting a lack of focus on this critical patient population.
Researchers examine the mechanisms underlying inactivation of BRCA1 and its impact on patient management. The study assesses the potential usefulness of BRCA1 as a prognostic tool and predictive marker for response to different classes of drugs.
A new experimental technique called adoptive transfer has shown significant promise in treating metastatic melanoma by replacing immune cells with those specifically designed to destroy tumors. The treatment resulted in at least 50% tumor shrinkage in six patients, with no growth or appearance of new tumors.
A new clinical trial is investigating the combination of high-dose calcitriol and docetaxel in treating advanced prostate cancer, with the goal of reducing PSA levels by 50% or more. The study builds on promising preliminary results from a previous Oregon Health & Science University trial.
Researchers conducted a Phase I clinical trial of endostatin, showing that it decreases blood flow to tumors and promotes the death of cancer cells. The study also found minor anti-tumor activity in two patients, but no long-term responses were seen.
A study of 270 patients found that bladder cancer recurrence rates increased with each episode, with the average time to second and third recurrences decreasing by 15 and 13 months respectively. Patients whose original tumors tested positive for the Ki-67 marker were at higher risk for first recurrence.
A study found that nearly all patients with cancer reported improved well-being from using alternative therapies, but used these therapies primarily for general health, not as a substitute for conventional medicine. Cancer patients who were female, college-educated, or younger were more likely to use alternative treatments.
A recent study by Ohio State University researchers found that cancer patients with a history of mood disorders are most at risk for developing post-traumatic stress disorder (PTSD). The study suggests that doctors should screen all cancer patients for depressive and anxiety symptoms, particularly those with past mood disorders.
A phase III trial found that darbepoetin alfa reduced blood transfusions by half and increased hemoglobin levels, while decreasing fatigue. The treatment also showed similar adverse events to those in cancer patients receiving chemotherapy.
A study found that St. John's wort significantly lowers blood levels of irinotecan's active metabolite SN-38 by 42%, decreasing detoxification and reducing overall antitumor activity. Patients receiving chemotherapeutic treatments with St. John's wort may need to increase drug dosage.
A major NCI study reveals that long-term survivors of Hodgkin's disease are twice as likely to develop a solid tumor compared to the general population. The study found that certain treatments for Hodgkin's disease increase the risk of second cancers, but effective therapies have a significant survival benefit.
A study by University of Minnesota researchers found that morphine activates the MAPK signaling pathway in human endothelial cells, promoting angiogenesis and tumor growth. The findings could lead to new treatments for managing cancer pain while minimizing tumor growth.
Researchers found physicians and patients were equally likely to use sun protection when going outside for an hour or more. However, the specific forms of sun protection used differed, with physicians using sunscreen more frequently but less often staying in the shade or wearing protective clothing.
Researchers at Thomas Jefferson University are conducting a study on Mindfulness-Based Art Therapy (MBAT) to reduce psychological stress and medical symptoms in cancer patients. The therapy combines creative expression, meditation, and art-making to improve overall quality of life.
A panel of experts calls for improved symptom management for cancer patients, citing undertreatment of pain, depression, and fatigue. The panel emphasizes the need for evidence-based treatments and routine assessment tools to ensure optimal symptom control.
The Prostate Interactive Educational System (PIES) is an interactive, computer-based program designed to provide comprehensive information tailored to the patient's preferences. The program will present disease and treatment information, a virtual support group, and allow patients to jot down notes in a virtual notebook.
A new assessment method using a patient questionnaire and computer-generated risk score has been developed to identify people at high risk of colorectal cancer. The system was tested on 2268 patients with adverse colorectal symptoms, detecting nearly all cancers (99%) by investigating just over half (57%) of the patients referred.
A study published in Journal of Clinical Oncology found that self-taught stress management techniques, such as progressive muscle relaxation and guided imagery, can significantly improve the quality of life for cancer patients undergoing chemotherapy. These techniques were more effective than traditional methods when learned independen...
Researchers at Massachusetts General Hospital developed a tri-modality approach to combat invasive bladder cancer, combining surgery, radiation, and chemotherapy. The treatment strategy showed comparable ten-year survival rates to radical bladder removal, with 90% of patients surviving without bladder removal.