Articles tagged with Cancer Patients
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Researchers found that specific variants of dopamine transporter and receptor genes associated with higher dopamine levels in the brain facilitated smoking cessation. This study highlights the importance of genetic investigations beyond single gene effects.
A study found that physicians have distinct approaches to explaining clinical trials, which can impact patient enrollment. The research suggests that understanding these differences is crucial for improving doctor-patient interactions and overall care.
The EU's new clinical trial directive may hinder international collaborations, leading to delays in cancer treatment development. This could result in patients being deprived of life-saving treatments, as the effectiveness of new drugs would be determined solely by pharmaceutical industry-sponsored research.
In Sweden, rectal cancer patients have seen a dramatic improvement in five-year survival rates, jumping from 50% to 60%, thanks to changes in hospital practice and quality assurance measures.
A large-scale clinical study by Nordic collaboration has provided new insights into the effects of chemotherapy in colorectal cancer. The analysis demonstrated that among 2,223 patients, those given chemotherapy as part of routine care had a five-year survival rate of 56%, compared to 49% for those treated by surgery alone.
A 57-year study found that hereditary retinoblastoma patients have a significantly higher risk of developing a second primary cancer, with an increased incidence of melanomas and sarcomas. The risk is independent of radiotherapy treatment.
A new coalition of cancer patients is working to promote better treatment, care, and research across Europe. The group hopes to influence European health policymaking and ensure access to high-quality screening, treatment, and care for all cancer patients.
Researchers identify key genes involved in cancer development, including BRAF, and develop targeted drugs to combat the disease. A new approach to cancer treatment is being explored by targeting mutated genes, offering new hope for more efficient treatments.
The European Cancer Patient Coalition is hindered by language barriers, with fewer than 50% of Europeans speaking a second language, including English. Digital divide also persists, with varying internet access across countries, affecting the coalition's ability to operate effectively.
Researchers have made significant progress towards a vaccine for pancreatic cancer, with one patient out of ten remaining disease-free after five years and two others surviving over two years. While the study's findings are promising, caution is advised due to the small sample size and potential biases in the selection process.
Breast cancer patients participating in an online support group experienced improved well-being and empowerment through sharing personal experiences, asking for advice, and expressing emotions. The study highlights the importance of internet access for social support and low-income groups.
A new study found that a rapid increase in the incidence of esophageal and gastric cardia adenocarcinomas is linked to modifiable risk factors such as smoking, being overweight, and gastroesophageal reflux. High serum levels of vitamin E are associated with reduced risk of upper gastrointestinal cancers.
Patients who traveled farther for cancer treatment had improved overall and progression-free survival rates, suggesting that access to information and resources plays a crucial role in cancer outcomes. The study's findings highlight the importance of considering travel distance as a potential factor in phase II clinical trial results.
Patients who traveled at least 15 miles for care had a one-third lower risk of dying during the trial and follow-up period compared to those living closer. The study found that patients with higher incomes, more education, and a supportive social network tended to fare better in terms of survival rates.
Researchers have developed a program to train cancer registrars to track patients' comorbidities, increasing the accuracy of cancer profiles and treatment outcomes. The method is easy for registrars to learn and has shown significant improvements in patient care.
A new study has found that the protein EZH2 is linked to aggressive and deadly breast tumors, with higher levels corresponding to worse patient outcomes. The discovery may lead to a new test for determining breast cancer prognosis more precisely.
Researchers found that wrist bands with acupressure or stimulation applied to an acupuncture point on the wrist reduced nausea in breast cancer patients by 15% compared to no band. Patients who expected the bands to ease their nausea experienced even greater relief, reporting a 25% decrease in nausea severity.
Two new studies found that elderly lung cancer patients benefit equally from aggressive chemotherapy and radiation treatment, contradicting common assumptions. Fit elderly patients should be fully briefed on treatment options, including potential risks and benefits. The studies suggest presenting the full range of treatment options to ...
A new study reveals that patients who received neoadjuvant chemotherapy lived an average of 31 months longer than those treated with surgery alone. The combination therapy showed a 66% greater chance of surviving bladder cancer.
A new nomogram model predicts prostate cancer likelihood in men with PSA levels below 10 ng/ml, helping to reduce unnecessary biopsies. The model identifies four independent risk factors for positive biopsy results and provides a score to calculate the likelihood of cancer presence.
A recent study found that symptoms of depression are a consistent predictor of shortened survival in cancer patients. After accounting for other factors, researchers discovered that depressive symptoms were the most significant psychological indicator of poor outcomes.
A new test method aims to predict which early-stage cancer patients are at high risk for relapse, allowing for more precise treatment decisions. By analyzing apoptosis proteins in patient tumors, researchers hope to identify molecular and genetic signatures that indicate the likelihood of cancer recurrence.
Researchers have developed molecular markers that can predict radiation-induced late toxicity and disease recurrence in prostate cancer. The study used apoptosis assays to evaluate cell death induced by radiation, revealing correlations between lymphocyte apoptosis and toxicities.
Researchers at Wake Forest University Baptist Medical Center have found that oxaliplatin can effectively treat human cancers resistant to other platinum-based therapies. The drug works differently than cisplatin and shows promise in combination with radiation therapy for patients with earlier stages of rectal cancer.
Researchers used blood samples to analyze protein patterns and determine if biopsies were necessary. The test showed a sensitivity of 100% and specificity of 67%, suggesting it could save over 50% of biopsies. The study's results may lead to more accurate cancer detection and tailored therapy for individual patients.
The Lombardi Cancer Center will investigate how drinking affects breast cancer risk, focusing on estrogens, free radicals, and gene mutations. The center aims to improve public health recommendations and inform individual lifestyle choices.
A national study found that 43% of patients reported nausea on the day of treatment, and 73% experienced nausea one or more days later. Delayed nausea is a significant problem, affecting twice as many patients who felt ill in the following days compared to those who felt queasy initially.
Researchers found a slightly increased risk of ovarian cancer in women with endometriosis, with a half-life increase and higher risks for younger women. In contrast, the risk of cervical cancer was reduced by roughly a third. Further investigation is needed to understand the connection between endometriosis and cancer.
Researchers found that the p53 gene plays a crucial role in distinguishing which lung cancer patients are most likely to survive four years or more. The study identified a sub-group of early-stage lung cancer patients without p53 mutations who had a significantly higher survival rate, providing hope for a new treatment approach.
A phase II multicenter collaborative study found that Velcade significantly reduced disease in 67% of patients with advanced multiple myeloma, with some achieving complete or near-complete responses. The drug has shown great potential to improve patient outcomes in this incurable disease.
Researchers at UW-Madison will enhance the Comprehensive Health Enhancement Support System (CHESS) with new functions tailored to individual needs. The center's projects aim to improve patient outcomes, quality of life, and cost-effectiveness in cancer communication systems.
The Society of Nuclear Medicine has announced an image that represents a significant advance in achieving high throughput in PET scanning without sacrificing quality. The image showcases technology such as 3D-LSO PET/CT, which could decrease whole-body scan duration substantially, benefiting nuclear medicine professionals and patients.
Researchers have developed a new treatment strategy that combines chemo-radiation and surgery to prevent recurrence of rectal cancer. The study, conducted by Professor Andres Cervantes' team, demonstrated excellent results with no local relapse after two years.
A study suggests that extending screening intervals could reduce lead-time bias and overdetection rates associated with prostate cancer screenings. The research estimates a potential 60-90% increase in prostate cancer incidence, highlighting the need to weigh benefits against risks.
Researchers found that AIDS-related lymphomas responding well to chemotherapy have high levels of proteins indicating rapid growth and multidrug resistance. The study also showed that suspending antiretroviral therapy during lymphoma treatment is safe and allows for high overall survival.
Drs. Chang and Moore were awarded the Mott Prize for their discovery of KSHV, a virus linked to Kaposi's sarcoma, the most common malignancy in AIDS patients. Their work has opened new areas in cancer research and will continue to use innovative techniques to understand KSHV's impact on cancer.
Researchers found NRAS mutations in 95% of primary hereditary melanomas, but only 10% of sporadic melanomas. The study suggests a link between UV light exposure and the activation of NRAS mutations in early stages of melanoma development.
Researchers at Michigan Medicine have identified 158 genes specific to pancreatic cancer in a new study, providing a more accurate accounting of the disease's molecular makeup. The team hopes to use this knowledge to develop new diagnostic tests and treatments tailored to individual patients.
Researchers at The Wistar Institute developed DNA arrays to accurately diagnose Sezary syndrome, a leukemic variant of cutaneous T-cell lymphoma. The technology identified genetic markers that can predict patient survival and identify potential drug targets.
A study found that examining lymph nodes in women with early-stage uterine cancer can prevent unnecessary radiation therapy and improve treatment outcomes. The researchers analyzed data from 144 women diagnosed with grade 1 endometrial cancer, finding that lymph node removal saved patients from unneeded radiation therapy in 22 cases.
The Ireland Cancer Center's Phase I and II trials report remarkable responses to new therapies for skin lymphoma, multiple myeloma, and solid tumors. These innovative treatments overcome common complications like kidney and liver damage, offering hope to patients with limited treatment options.
A new study found that chemotherapy and radiotherapy together reduce surgery and removal of the voice box due to cancer recurrence. The combination treatment was associated with a significantly lower rate of surgeries compared to standard therapy or radiotherapy alone.
A new study found that the California law SB 37 has eliminated a major barrier to cancer clinical trial participation, with no patients citing insurance limitations as a reason. Participation rates have increased from 51% to 69%, but further awareness campaigns are needed to raise rates more dramatically.
The GELA study reveals that MabThera plus CHOP improves three-year event-free survival by 18% and overall survival by 11%, with no increased toxicity. This breakthrough treatment offers a potential cure for aggressive NHL, which affects 55% of the 1.5 million people worldwide suffering from non-Hodgkin's lymphoma.
An early clinical trial at Cedars-Sinai Medical Center shows 2C4 effectively shrank tumors in several types of cancer, targeting a common growth signaling pathway. Eighteen out of twenty-one patients responded to treatment, with some achieving partial remission and stabilizing disease for over a year.
A study by the University of Rochester Medical Center found that childhood cancer survivors are at risk of cardiovascular problems, including cardiomyopathy and premature atherosclerosis. The research also showed that these survivors were less active and had different body compositions compared to their siblings.
A study by Chandra P. Belani and colleagues found that elderly patients with advanced NSCLC can tolerate combination therapy safely and effectively, with median survival rates comparable to those of younger patients. The treatment regimens used in the study were weekly paclitaxel in combination with full doses of carboplatin.
A study by Dr. Barbara Andersen and Kristen Carpenter found that women with gynecological cancers face significant sexual adjustment issues due to complex recovery processes. The researchers identified key factors influencing sexual adjustment, including relationship satisfaction and emotional state.
A study of 7,257 patients with rectal cancer found that those treated at high-volume hospitals had lower mortality rates and higher survival rates compared to those treated at low-volume hospitals. Patients at high-volume hospitals also experienced a lower risk of permanent colostomy.
Researchers found that low blood levels of selenium are a risk factor for progression of Barrett's esophagus and that higher levels of selenium may inhibit the progression of this condition. The study suggests that adequate selenium consumption may lower cancer risk in people with Barrett's esophagus.
A high-calorie diet may increase chances of surviving bowel cancer for longer, with patients on low and moderate energy intakes around three times as likely to die within five years compared to those on a high intake. Female sex, being under 65, and location of the tumour were found to be factors increasing survival rates.
Multidetector CT (MDCT) accurately identified 66 out of 71 total cancers found after additional tests and surgery, including small cancers under 5mm in diameter. MDCT offers a more comfortable and time-efficient alternative to excretory urography for detecting urinary tract abnormalities.
A new study found that spiritual well-being can significantly impact the mental health of terminally ill cancer patients. Patients with high spiritual well-being were less likely to experience strong feelings of hopelessness and suicidal thoughts. The research highlights the importance of addressing spiritual needs in palliative care.
A study found that MR imaging identified 86% of residual disease, outperforming mammography in detecting disease near the lumpectomy site. The imaging modality was also most accurate in identifying disease in different quadrants than the original tumor site.
A recent study shows that whole body PET scans are twice as sensitive as CT scans in detecting breast cancer spread, with a higher accuracy rate of 93% compared to 46%. This breakthrough technology also offers less radiation exposure to patients, making it a more efficient and safer option.
A study published by the American College of Radiology found that PET scans had a sensitivity rate of 93% compared to 46% for CT scans. Additionally, PET scans offered advantages over CT scans in terms of cost savings due to lower radiation exposure. The researchers recommend using PET scans for staging patients with suspected cancer s...
A new contrast agent has been shown to be 92% accurate in identifying malignant disease using MR imaging, outperforming CT scans in diagnosing testicular cancer metastases. The agent enhances lymph node signal intensity, allowing for earlier detection of disease.
The Stanford study found that FDG-PET is highly effective for lung nodule diagnosis but most cost-effective when used selectively with CT scans. The researchers recommend relying on CT as the initial test for almost all patients and using FDG-PET in cases where the risk of cancer conflicts with CT results.
A study by Michael DeBaun and colleagues found that children with neuropathic pain require significantly higher doses of morphine and benzodiazepine than those without. Using methadone as an alternative, the team discovered a more effective treatment approach for pain relief in these patients.
A study published in the Journal of the National Cancer Institute found that only 40% of patients with superficial bladder cancer had regular follow-up examinations, despite recommended guidelines. Patient characteristics such as age, ethnicity, and socioeconomic status were independently associated with low-intensity surveillance.