The World Health Organization predicts 15 million new cancer cases annually by 2039, with 70% occurring in developing countries. Anti-cancer factions are pooling knowledge and resources to establish a system to better equip healthcare organizations for the growing challenge.
Researchers have developed a cancer vaccine that targets telomerase, a protein responsible for cancer cells' unlimited division. The vaccine has shown promise in encouraging an immune response in patients with pancreatic cancer, leading to longer survival rates.
A Cardiff-based team investigates the impact of genetic testing on insurance costs and behavior in the UK. They gather data on families affected by inherited diseases to determine the potential for adverse selection and its effect on insurance claims and premiums.
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A new radium isotope, radium223, has shown promise in treating skeletal metastases with less damage to bone marrow compared to traditional treatments. The isotope is incorporated into skeletal tissue via osteoclasts and emits radiation that kills cancer cells, providing pain relief and potentially improving quality of life.
Kytril was found to be significantly more effective than dolasetron in controlling acute chemotherapy-induced nausea and vomiting. The study, led by Dr. Marianne Tan, showed that 69.2% of patients treated with Kytril experienced total control of nausea and vomiting, compared to 23.1% for dolasetron.
A new clinical trial, led by Scott Waldman, aims to determine if a test for the protein guanylyl cyclase C can accurately diagnose colorectal cancer spread. The test may improve diagnoses and treatment outcomes by detecting tiny amounts of cancer in lymph nodes.
University of Pittsburgh researchers found combined PET/CT scans to be a valuable tool for staging and re-staging patients with difficult-to-track cancers. The technology identified additional cancerous lesions in 80% of ovarian carcinoma patients and 45% of cervical carcinoma patients, leading to changes in treatment plans.
Researchers at Ohio State University have developed an intensification therapy regimen that combines chemotherapy and radiation to treat advanced head and neck cancers. The treatment has shown promising results, with a significant increase in survival rates and minimal patient non-compliance.
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The study found significant variations in cancer prevalence across European countries, with high rates in Sweden, Switzerland, and Germany, and low rates in Poland, Estonia, Slovakia, and Slovenia. The research team suggests that cancer prevalence is closely linked to economic development and survival rates.
Breast cancer researchers found that registry data accuracy is higher for hospital-based services than ambulatory services, suggesting registries can improve cancer care quality. Additionally, a study suggests blocking growth factor receptors may suppress regional metastases but not distant lung metastases.
Researchers found that implantable pain pumps improved cancer patients' quality of life by increasing survival rates, reducing pain and side effects. Patients treated with the pump had significantly less fatigue, constipation, and nausea compared to those on medical management.
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In a Phase I trial, patients receiving recombinant Angiostatin with radiation showed significant tumor regression and minimal toxicity. The findings support the safety of Angiostatin when combined with radiation therapy, paving the way for future trials of combination therapy.
The study demonstrated that gemcitabine was well-tolerated in patients with superficial bladder cancer, with no or very low levels of the drug found in plasma samples. The results suggest that gemcitabine may be a suitable alternative to current standard treatments, which often cause toxic side effects.
A new study by UC Davis Cancer Center found that patients need practical information about how to participate in clinical trials. Informed patients are more likely to have autonomy, be satisfied with their treatment, and stick with a clinical trial through its completion.
A study by Philip Breitfeld shows that initial hospital treatment costs can top $75,000 per child, but the average cost per year of life saved is just $2,700. Insurers lack access to data to justify spending on curative cancer therapies, leading to denied payments for high-priced procedures.
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Research found that chronic alcohol consumption led to a decrease in survival of melanoma-bearing mice due to body fat loss, suggesting potential risks for human cancer patients. The study also highlights the role of leptin in modulating immune function and cancer progression.
Researchers suggest that drugs blocking the ICAM1 gene could reduce lung scarring caused by radiation therapy, potentially improving patients' breathing and exercise abilities. In a study, mice lacking this gene showed improved pulmonary function tests and reduced fibrosis, indicating inflammation's role in lung scarring.
A randomized study of 143 patients found that Zevalin, a new radioimmunotherapy drug, significantly improved tumor shrinkage and complete remission rates compared to standard chemotherapy. The study results demonstrate the effectiveness of Zevalin in treating B cell non-Hodgkin’s lymphoma.
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Researchers at Duke University Medical Center investigated the impact of taste and smell deficits on cancer patients' weight loss and nutritional status. Adding flavor-enhancing powders derived from foods like cheese, bacon, garlic, and fruits showed promise in improving appetite and immune function.
Researchers found a 16% increased risk of death for blacks compared to whites with comparable treatment, which narrowed to 7% after adjusting for other causes. The disparity was eliminated in most cancers, except for breast and two rare types.
The study found that older patients fared better at high-volume hospitals for certain high-risk surgeries, including cancer and heart valve replacements. Higher volume hospitals had lower death rates compared to lower volume hospitals, particularly for patients over 65.
Researchers are developing a new method to improve the diagnosis of prostate cancer by using contrast-enhanced ultrasound. The study aims to identify areas in the prostate with more blood vessels, allowing for targeted biopsies and potentially reducing the number of unnecessary procedures.
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A new study found that PET scans can reduce unnecessary colorectal surgeries by detecting disease earlier than other imaging modalities. The study analyzed 96 patients and found that PET scans led to active treatment for 12% of them, while conventional imaging indicated rising cancer markers in 10 cases.
The NCCN has released new guidelines to address cancer-related fatigue and treatment-related anemia in cancer patients. The guidelines provide a framework for clinicians to assess and treat these conditions, with a focus on symptom management and improving patient outcomes.
The Rush University Medical Center has opened a new tissue and cell lab to develop clinical-grade human cellular components for treating certain cancers. The facility will utilize immunotherapy, using the patient's own cells to target cancerous cells.
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A new study found that doctors who received training in communication skills showed significantly more positive attitudes towards psychosocial issues and exhibited patient-centered behavior. The results suggest that a three-day course can make a lasting impact on doctors' communication styles, leading to better patient outcomes.
A new study has validated data on 73 patients with lymph-node negative breast cancer under 55, predicting disease-free survival with 90% certainty. This could lead to a 30-40% reduction in chemotherapy use for these patients, resolving the dilemma of overtreatment.
Researchers found that thrombocytosis correlates with more aggressive ovarian cancer and poorer response to treatment. Patients with thrombocytosis had higher CA-125 levels, advanced stage disease, and greater tendency of cancer spread.
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A new study reveals that rats with chronic pain from inflammation were more tolerant of painful heat stimuli and had less swelling when fed a diet based on soy protein. The findings suggest that a soy diet may reduce the need for opioid medications, which are often associated with severe side effects.
A study found that high-volume mammography readers in the US detected fewer cancers than their British counterparts, despite meeting lower annual standards. The research suggests re-engineering US screening programs to improve efficiency and quality without increasing interventions.
Researchers at the University of Sydney found that cancer patients' informational and emotional needs are often not detected or addressed by oncologists. Despite this, patients' satisfaction with consultations and anxiety levels remain unaffected, highlighting the importance of doctors actively encouraging emotional disclosure.
A study of 228 lung cancer patients aged 65+ found that severe symptoms and social functioning are strong predictors of depression. Patients who had not received radiation therapy within 40 days were also more depressed, highlighting the importance of symptom management in older cancer patients.
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A study found that relaxation techniques learned prior to cancer treatment reduced anxiety more effectively than those taught during treatment. These techniques also eased symptoms of nausea, pain, and emotional adjustment issues, helping patients feel more in control of their treatment.
Researchers warn that patients with testicular cancer are living long enough to suffer from life-threatening side effects, including cardiovascular disease. Studies found that nearly a third had abnormal heart function, while over 80% had raised cholesterol levels.
Researchers at the University of Maryland Greenebaum Cancer Center developed a new method using artificial neural networks to differentiate between two types of colon tumors. The study successfully diagnosed 12 out of 12 samples and reduced the number of genes necessary for diagnosis from 8,064 to 97.
Researchers found that cancer patients tend to lower their expectations to match their reality, leading to decreased anxiety and depression. However, spouses of cancer patients experienced increased anxiety and depression due to unchanging life values and care-taking responsibilities.
The Mayo Clinic study found that the risk of progression from MGUS to multiple myeloma or related cancers is approximately one percent per year, with larger M-protein levels increasing the risk. Patients with very small protein levels had a 14% progression rate at 20 years, while those with high levels had a 60% progression rate.
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Breakthrough pain in cancer patients incurs $12,000/year in medical services; non-breakthrough patients incur $2,400/year. Study finds link between breakthrough pain and increased need for hospitalizations, emergency room visits, and doctor visits.
A recent study found that social factors can significantly affect the survival rates of lung cancer patients, with African Americans facing higher mortality rates due to poorer physical performance and weight loss. The researchers adjusted for these factors in their analysis, finding no difference in outcomes between ethnic groups.
The innovative procedure uses a 40-second CT scan to identify colon polyps, reducing the risk of puncturing and sedation. Virtual Colonoscopy has been shown to detect polyps as small as 3mm in diameter with high accuracy.
A retrospective analysis of 574 patients with non-small cell lung cancer found that older patients tolerated chemotherapy regimens comparable to younger patients. However, psychological distress and neutropenia were more prevalent in the elderly population. The study suggests that functional status is a key factor in determining treatm...
A new study reveals a reliable method for identifying proximal colorectal cancers through faecal DNA analysis. The test, which detected mutations in the BAT26 gene, showed zero false positives and high specificity.
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A new study finds that prostate-specific antigen (PSA) is clinically unreliable for diagnosing prostate cancer, with low levels not meaningfully related to the disease. Prostate cancer is being over-diagnosed and over-treated due to a misconception about PSA's role in the disease.
A study published by the Mayo Clinic found that megestrol acetate was more effective than dronabinol in improving appetite and weight loss in patients with advanced cancer. The study, which evaluated 469 patients, showed that 75% of those taking megestrol acetate reported appetite improvement, compared to 49% of those taking dronabinol.
Researchers found that genetic imbalances on chromosomes 8 and 18 were better predictors of colorectal cancer prognosis than conventional assessments. The study used a new approach to investigate chromosome imbalances in early-stage cancers, with patients experiencing varying disease-free survival rates based on their tumour balance.
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A strong patient-physician relationship is crucial to obtaining needed health services, the study found. Primary care systems that prioritize accessibility, coordination, and comprehensive care can lead to stronger relationships between patients and physicians, ultimately improving health outcomes.
A new treatment combining CPT-11 and cisplatin has shown superior results in prolonging survival for patients with small-cell lung cancer. Patients receiving this treatment had a 55% improvement in one-year survival and were four times more likely to be alive at two years.
A two-step approach combining high-dose chemotherapy and autologous stem-cell rescue with mini-transplantation from a sibling significantly reduces transplant-related complications and increases survival rates for patients with advanced-stage multiple myeloma. The procedure results in mild to moderate treatment-related toxicities and a...
A study by UCSF found that cancer patients often prefer to experience pain over the side effects of opioid analgesics. Effective pain management requires repeated assessment and adjustments in dosage, according to experts.
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A new UCSF study found that many cancer patients are not taking around-the-clock and as-needed pain medicines as prescribed by their physicians. This results in inadequate pain relief, with only 29.2% of patients receiving both long-acting and short-acting opioids.
A new study found that 71% of adult cancer patients knew they might not benefit directly from participating in clinical trials, while less than 40% recognized potential risks or discomfort. Despite this, patients were highly satisfied with the informed consent process and reported no pressure from physicians.
Researchers at the University of Pittsburgh Medical Center have identified cyclin B1 as a promising new tumor antigen for cancer vaccine development. The study found that cyclin B1 is over-expressed in breast and lung cancer cells, making it an attractive target for immunotherapy.
The study found that PET scans changed treatment for 63% of patients with recurrent lung cancer, with a significant impact on patient care and well-being. For newly diagnosed patients, PET results led to changes in staging and treatment planning, impacting 42% of cases.
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Researchers at UNC will follow 1,000 newly diagnosed colon cancer patients for five years to study the impact of health literacy on patient outcomes. The study aims to improve survival rates and quality of life for patients with colon and lung cancers.
A recent survey conducted by the Fred Hutchinson Cancer Research Center found that nearly three-quarters of pediatric cancer patients in western Washington use alternative therapies. The most common types of alternative medicine used were herbal and high-dose vitamin supplements, which were reported to have substantial improvements in ...
Introgen's gene drug demonstrates tumor growth control by targeting the mda-7 gene, a key tumor suppressor. The study shows that replacing the mda-7 function in cancer cells can stop tumor growth and is promising for treating advanced melanoma.
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Cancer patients' dietary needs vary according to disease stage, with underweight patients benefiting from fatty foods and those well-recovering advised on traditional healthy diets. The study found that nearly two-thirds of patients changed their eating habits since diagnosis, with most taking nutritional supplements.
A new computer tool forecasts individualized treatment outcomes and risk assessments for patients with breast cancer. The program provides easy-to-read reviews of different treatment options, helping patients make informed decisions about their care.
A pioneering combination of radiotherapy and chemotherapy has shown promising results in treating common cancers, including cervical, testicular, ovarian, bladder, and small cell lung cancer. Survival rates have increased by up to 18% with combined treatment, outperforming traditional radiotherapy alone.
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A new approach reduces lymph node removal in breast cancer patients, reducing surgical trauma and complications. The technique uses a radioactive tracer to locate the sentinel node, allowing for targeted biopsy and minimizing false negatives.