Articles tagged with Cancer Patients
Dr. Robert D. Schreiber receives AACR-CRI Lloyd J. Old Award in Cancer Immunology for his groundbreaking contributions to the field of cancer immunology, including identifying IFNγ as a key cytokine and developing the cancer immunoediting concept.
Researchers have found a potential new treatment for patients with advanced melanoma and kidney cancer. The study used an antibody that targets the tumor-enhancing protein TGFβ, which is involved in cell growth and spread of tumors.
A recent study by Queen's University Belfast highlights the disparities in cancer care for older patients, citing 'undertreatment' and a 'survival gap'. The editorial argues that clinical trials should be without an upper age limit to redress these disparities and improve outcomes.
A new pill called idelalisib shows promise in treating relapsed leukemia and lymphoma patients, with a significant response rate of 72% for CLL patients. However, MCL patients experienced less favorable responses, highlighting the need for further research to improve this therapy.
Dr. Daniel D. Von Hoff, a leading physician and scientist, has made significant advancements in cancer treatment with the development of multiple anticancer agents, including gemcitabine and nab-paclitaxel. His work has improved patient care and survival rates for patients with stage IV pancreatic cancer.
Researchers identified cancer markers and a previously unknown gene role in airways of smokers with lung cancer, suggesting earlier detection and treatment strategies. The study found that normal-appearing tissue near tumors has tumor-associated molecular abnormalities, potentially aiding in diagnosis and treatment.
Researchers found that injecting a virus directly into one melanoma tumor can induce a potent anti-tumor immune response, destroying both infected and non-infected tumors. This combination therapy overcomes the limitations of oncolytic virotherapy and checkpoint blockade.
The Northwestern Medicine Developmental Therapeutics Institute has received a significant $2 million pledge from The Woman's Board of Northwestern Memorial Hospital. This funding will support the launch of the institute, establish its first clinics, and create a fellowship program for physician-scientists specializing in developmental ...
Research suggests that palliative chemotherapy can lead to more invasive medical procedures and a higher risk of death in intensive care units among advanced cancer patients. The findings highlight the need for clearer discussion of the harms and benefits of palliative chemotherapy at the end of life.
Research suggests that terminally ill cancer patients who receive chemotherapy in the last months of life are more likely to undergo intensive medical care and die in an intensive care unit. The study highlights the importance of end-of-life discussions between patients and physicians.
Patients receiving nivolumab survived for an average of 16.8 months, with 62% alive one year after treatment initiation and 43% alive two years later. The drug also shrank tumors in 31% of patients, with some able to remain on the treatment for up to two years.
Dr. Curtis Harris is being recognized for his landmark scientific contributions to the fields of integrative and molecular epidemiology of human cancer and cancer biomarkers. His research has significantly impacted the field of cancer risk assessment and our understanding of the molecular pathogenesis of human cancer.
Researchers at Ohio State University found that inhibiting the enzyme PRMT5 can significantly improve survival in an animal model of GBM. High levels of PRMT5 are associated with aggressive growth and lower overall survival rates in brain cancer patients.
Researchers from the University of Surrey launch eSMART, a programme using mobile phone technology to remotely monitor patients undergoing chemotherapy for breast, bowel and blood cancers. The system assesses symptoms and triggers alerts to doctors or nurses within minutes.
Researchers discovered an unusual genetic mutation in patients with fibrolamellar hepatocellular carcinoma, a rare and aggressive form of liver cancer. The mutated gene, called a chimera, is constantly active and drives the growth of tumor cells.
A recent study found that patients with invasive lobular carcinoma receive less benefit from standard adjuvant therapies compared to those with ductal carcinoma. The research indicates a potential target for drug therapy in future clinical trials, which could lead to more effective treatment options for this subtype of breast cancer.
A new study published in Supportive Care in Cancer has linked handgrip strength to survival rates among patients with advanced-stage cancers. The test measures peak grip strength using a simple device called a dynamometer, providing a direct assessment of body strength and helping doctors determine interventions needed.
In the UK, bladder cancer is the 7th most common cancer and has a high recurrence rate, affecting 28 people daily. Early detection is crucial, as 5-year survival rates can be as high as 80% if treated early.
A new American Cancer Society study reveals that uninsured adolescents and young adults are disproportionately diagnosed with late-stage cancer due to lack of insurance. The research suggests that expanding health coverage, such as the Affordable Care Act, can lead to fewer late-stage diagnoses and ultimately save lives.
A study published in Cancer Epidemiology, Biomarkers & Prevention found that cancer patients seeking information from non-clinician sources were more likely to receive PET scans. The study suggests that exposure to cancer-related information and promotional materials may drive the use of unnecessary imaging procedures.
Secondary thyroid cancer is more deadly for young individuals compared to primary thyroid cancer. This study highlights the importance of screening young cancer survivors to detect potentially life-threatening tumors.
A new study found that each individual patient's molecular profile in pancreatic cancer is unique, with different genes and pathways disrupted compared to the group of patients as a whole. The researchers argue for personalized medicine, where treatment is tailored to each person's individual disease etiology.
Researchers found that sparing the contralateral submandibular gland during radiation therapy is possible with advanced stage cancers. The study involved 71 patients who received treatment to the bilateral neck, with no recurrences in the spared gland at a median follow-up of 27.3 months.
A retrospective analysis found that HPV-positive oropharyngeal squamous cell carcinoma patients had a higher overall survival rate than HPV-negative patients after disease progression, with median survival being nearly twice as long. The study also showed improved outcomes for patients who underwent surgery after cancer recurrence.
A study published in PLOS Genetics reveals that nearly 100 genes may explain the lower cancer incidence rate in patients with central nervous system diseases. Researchers found that specific genes were inversely activated in both diseases, suggesting a protective effect against cancer.
A study found that sparing bilateral level IB lymph nodes during radiation therapy for oropharyngeal cancer significantly improved patient-reported xerostomia scores. This reduction also led to lower radiation doses to nearby salivary organs, causing less damage to post-treatment salivary function.
Researchers at Memorial Sloan Kettering Cancer Center reported remarkable results from a clinical study using genetically modified T cells to treat advanced leukemia. The treatment achieved a 88% complete remission rate, exceeding the response rate of salvage chemotherapy alone.
A Phase III clinical trial found no significant improvement in overall survival or progression-free survival with bevacizumab treatment for new glioblastoma patients. Researchers also observed increased symptoms and neurocognitive decline among non-progressing patients treated with bevacizumab.
A four-year clinical study involving 461 patients with advanced cancers showed that earlier palliative care significantly improved quality of life and patient satisfaction. The study demonstrated the benefits of cancer centers providing early specialized palliative care in outpatient clinics.
A new MRI-based method detects tumors in young cancer patients without exposing them to radiation, reducing the risk of secondary cancers. The technique uses a novel contrast agent and is as effective as PET-CT scans in detecting tumors.
A new study by Georgetown University Medical Center researchers suggests that implementing comprehensive tobacco control recommendations could reduce smoking rates by about 40% and prevent 50 million deaths. The study estimates that raising taxes on tobacco products would have the greatest impact in reducing smoking rates.
Cancer doctors can cut costs without risk to patients by improving end-of-life care, reducing unnecessary medical imaging, and negotiating lower prices for new cancer drugs. These changes can save billions of dollars in healthcare spending while maintaining quality of life.
Researchers at the University of East Anglia have made a significant advance in understanding genetic changes associated with terminal prostate cancer. A genetic mutation has been identified as a key factor in the development of aggressive cancer later in life. This discovery could help identify patients who are at risk of developing f...
A panel of 55 genes impacted by loss of protein SYK predicts invasive breast cancer, with better survival rates for patients without gene changes. Researchers found that 80% of patients without genetic alterations were still alive after 18 years, compared to 20% with gene changes.
A study found that patients with high levels of vascular endothelial growth factor (VEGF) in their blood had poor response to treatment with immunotherapy ipilimumab. Combining immunotherapy with VEGF inhibitors may be a potential option for these patients.
Researchers at Ohio State University Comprehensive Cancer Center identified a molecular pathway that enables cancer cells to grow in low-oxygen environments. By targeting this pathway, therapeutic strategies may be developed to inhibit tumor growth with minimal side effects.
Professor Patrick Johnston, alongside leading experts and patient groups, aims to address disparities in cancer care across Europe. The European Cancer Patient's Bill of Rights, launched on World Cancer Day, sets a standard for optimal cancer care for all European citizens.
A study published in Cancer Prevention Research found that atypical ductal hyperplasia and atypical lobular hyperplasia have similar potential to develop into breast cancer. The study followed over 700 women with biopsy-confirmed atypia for an average of 12.5 years, finding that the ratio of breast cancer development was the same in bo...
Researchers have identified potential therapeutic targets for muscle-invasive bladder cancer, including genes and pathways disrupted in the disease. The study also found similarities between subtypes of bladder cancer and those of other cancers, such as breast, head and neck, and lung cancers.
The University of California, San Francisco (UCSF) has received a $50 million gift from the Gordon and Betty Moore Foundation to establish its first dedicated women's hospital at Mission Bay. The new hospital will offer integrated care for women, including cancer treatment and reproductive care.
A new whole-body MRI scan has improved the treatment of myeloma cancer by accurately imaging the spread of cancer throughout the bone marrow. The scan showed high accuracy in identifying patient response to treatment, reducing the need for painful biopsies.
A study found that patients with ALK+ non-small cell lung cancer can continue treating with crizotinib after receiving targeted radiation therapy to eliminate resistant disease pockets. This approach improves 2-year survival rates compared to those who discontinued the drug earlier.
Adolescents and young adults undergoing cancer treatment benefit from a therapeutic music process that includes writing song lyrics and producing videos. This music therapy intervention improves resilience-related outcomes, including courageous coping and social integration.
A recent study by Loyola Medicine finds that many internists feel ill-equipped to care for adult childhood cancer survivors due to inadequate education and training. The study highlights the need for primary care physicians to have access to survivorship care plans and guidelines.
Researchers have made refinements to a technique combining MRI and near-infrared spectroscopy (NIRS) to improve image quality and accuracy in detecting breast cancer. The new design allows for increased coverage of the chest, providing improved visibility for 'hard-to-see' areas, and has shown promising results in clinical trials.
Researchers have successfully used the Cherenkov effect to capture and visualize radiation beams entering or exiting the human body. This breakthrough technology enables doctors to see the dose of radiation to the skin and detect errors in dosage, potentially reducing side effects like skin reactions during breast cancer treatment.
Researchers at VCU Massey Cancer Center are studying how the ACA affects cancer screening in low-income women and employed married women with breast cancer. The study found that Medicaid expansions increased breast and cervical cancer screening, particularly among low-income women, suggesting a positive effect of near-universal coverag...
A new study from Ohio State University Comprehensive Cancer Center found that the quality of cancer stem cells, rather than their quantity, may be associated with better survival rates in patients with HPV-related oral cancers. Researchers discovered that HPV-positive tumors had fewer cancer stem cells, contrary to previous expectations.
A new study found that combining high-dose interleukin-2 therapy with personalized tumor cell-based immunotherapy significantly improves patient survival rates. The treatment approach, which activates patients' immune systems using their own tumor cells, outperforms IL-2 alone in extending survival.
A study by St. Jude Children's Research Hospital found that childhood cancer patients are no more likely to develop post-traumatic stress disorder (PTSD) than their healthy peers. Despite a life-threatening diagnosis, young cancer patients reported benefits from the experience, including greater empathy and closer relationships with fa...
Researchers are developing a new diagnostic technique using infrared light to identify chemical changes in cells that lead to cancer development. The technology has the potential to detect alterations in both cancer and surrounding stromal cells, helping diagnosis and therapy development.
A new approach dubbed SMART has been shown to more than double three-year survival rates for mesothelioma patients treated with radiation therapy followed by surgery. The treatment approach, which involves an accelerated five-day course of intensity-modulated radiation therapy, reduces the risk of recurrence and improves quality of life.
The European Society for Medical Oncology warns that Eastern Europe lacks sufficient data, highlighting the need for a unified system. Despite this, many Western European countries are expected to have enough medical oncologists to meet growing cancer demands by 2020.
Patients treated with IMRT experience fewer side effects and lower cancer-related deaths compared to traditional radiation therapy. The study found that IMRT is a safe and beneficial treatment option for patients with head and neck cancer, with improved survival rates and reduced life-threatening recurrences.
A study found that 88% of participants opted for further investigation even if symptoms carried only a one per cent risk of indicating cancer. Patients cited peace of mind and early detection as main reasons for wanting more timely testing, highlighting the need for NHS guidelines to be revised.
Researchers discovered a genetic signature that implicates key immune system mechanism in driving acute lymphoblastic leukemia, the most common form of childhood cancer. The study found that genomic rearrangement and deletions of DNA segments drive cancer progression.
Researchers developed a nomogram to predict likelihood of overdiagnosis based on age, PSA level, and Gleason score. The tool aims to help patients and clinicians make informed decisions about treatment options.
Researchers have discovered a new drug delivery system that uses nanotechnology to effectively inhibit the growth of lung and head and neck cancer cells. The study found that nano-luteolin, a water-soluble polymer encapsulated form of the antioxidant luteolin, is highly effective in chemoprevention.
Researchers at Ohio State University discovered a seven-gene panel associated with DNA methylation that can identify patients with the best or poorest outcomes in acute myeloid leukemia (AML) treatment. Patients with low scores, indicating few highly expressed genes, had better complete-remission rates and longer survival rates.
The Sandra and Edward Meyer Cancer Center at Weill Cornell Medical College will use precision medicine and cutting-edge approaches to spur breakthroughs in cancer treatment. The center's efforts will be supported by a $75 million gift, which also names the new flagship building.