Articles tagged with Cancer Patients
Secondary thyroid cancer is more deadly for young individuals compared to primary thyroid cancer. This study highlights the importance of screening young cancer survivors to detect potentially life-threatening tumors.
A new study found that each individual patient's molecular profile in pancreatic cancer is unique, with different genes and pathways disrupted compared to the group of patients as a whole. The researchers argue for personalized medicine, where treatment is tailored to each person's individual disease etiology.
Researchers found that sparing the contralateral submandibular gland during radiation therapy is possible with advanced stage cancers. The study involved 71 patients who received treatment to the bilateral neck, with no recurrences in the spared gland at a median follow-up of 27.3 months.
A retrospective analysis found that HPV-positive oropharyngeal squamous cell carcinoma patients had a higher overall survival rate than HPV-negative patients after disease progression, with median survival being nearly twice as long. The study also showed improved outcomes for patients who underwent surgery after cancer recurrence.
A study published in PLOS Genetics reveals that nearly 100 genes may explain the lower cancer incidence rate in patients with central nervous system diseases. Researchers found that specific genes were inversely activated in both diseases, suggesting a protective effect against cancer.
A study found that sparing bilateral level IB lymph nodes during radiation therapy for oropharyngeal cancer significantly improved patient-reported xerostomia scores. This reduction also led to lower radiation doses to nearby salivary organs, causing less damage to post-treatment salivary function.
Researchers at Memorial Sloan Kettering Cancer Center reported remarkable results from a clinical study using genetically modified T cells to treat advanced leukemia. The treatment achieved a 88% complete remission rate, exceeding the response rate of salvage chemotherapy alone.
A Phase III clinical trial found no significant improvement in overall survival or progression-free survival with bevacizumab treatment for new glioblastoma patients. Researchers also observed increased symptoms and neurocognitive decline among non-progressing patients treated with bevacizumab.
A four-year clinical study involving 461 patients with advanced cancers showed that earlier palliative care significantly improved quality of life and patient satisfaction. The study demonstrated the benefits of cancer centers providing early specialized palliative care in outpatient clinics.
A new MRI-based method detects tumors in young cancer patients without exposing them to radiation, reducing the risk of secondary cancers. The technique uses a novel contrast agent and is as effective as PET-CT scans in detecting tumors.
A new study by Georgetown University Medical Center researchers suggests that implementing comprehensive tobacco control recommendations could reduce smoking rates by about 40% and prevent 50 million deaths. The study estimates that raising taxes on tobacco products would have the greatest impact in reducing smoking rates.
Cancer doctors can cut costs without risk to patients by improving end-of-life care, reducing unnecessary medical imaging, and negotiating lower prices for new cancer drugs. These changes can save billions of dollars in healthcare spending while maintaining quality of life.
Researchers at the University of East Anglia have made a significant advance in understanding genetic changes associated with terminal prostate cancer. A genetic mutation has been identified as a key factor in the development of aggressive cancer later in life. This discovery could help identify patients who are at risk of developing f...
A panel of 55 genes impacted by loss of protein SYK predicts invasive breast cancer, with better survival rates for patients without gene changes. Researchers found that 80% of patients without genetic alterations were still alive after 18 years, compared to 20% with gene changes.
A study found that patients with high levels of vascular endothelial growth factor (VEGF) in their blood had poor response to treatment with immunotherapy ipilimumab. Combining immunotherapy with VEGF inhibitors may be a potential option for these patients.
Researchers at Ohio State University Comprehensive Cancer Center identified a molecular pathway that enables cancer cells to grow in low-oxygen environments. By targeting this pathway, therapeutic strategies may be developed to inhibit tumor growth with minimal side effects.
Professor Patrick Johnston, alongside leading experts and patient groups, aims to address disparities in cancer care across Europe. The European Cancer Patient's Bill of Rights, launched on World Cancer Day, sets a standard for optimal cancer care for all European citizens.
A study published in Cancer Prevention Research found that atypical ductal hyperplasia and atypical lobular hyperplasia have similar potential to develop into breast cancer. The study followed over 700 women with biopsy-confirmed atypia for an average of 12.5 years, finding that the ratio of breast cancer development was the same in bo...
Researchers have identified potential therapeutic targets for muscle-invasive bladder cancer, including genes and pathways disrupted in the disease. The study also found similarities between subtypes of bladder cancer and those of other cancers, such as breast, head and neck, and lung cancers.
The University of California, San Francisco (UCSF) has received a $50 million gift from the Gordon and Betty Moore Foundation to establish its first dedicated women's hospital at Mission Bay. The new hospital will offer integrated care for women, including cancer treatment and reproductive care.
A new whole-body MRI scan has improved the treatment of myeloma cancer by accurately imaging the spread of cancer throughout the bone marrow. The scan showed high accuracy in identifying patient response to treatment, reducing the need for painful biopsies.
A study found that patients with ALK+ non-small cell lung cancer can continue treating with crizotinib after receiving targeted radiation therapy to eliminate resistant disease pockets. This approach improves 2-year survival rates compared to those who discontinued the drug earlier.
Adolescents and young adults undergoing cancer treatment benefit from a therapeutic music process that includes writing song lyrics and producing videos. This music therapy intervention improves resilience-related outcomes, including courageous coping and social integration.
A recent study by Loyola Medicine finds that many internists feel ill-equipped to care for adult childhood cancer survivors due to inadequate education and training. The study highlights the need for primary care physicians to have access to survivorship care plans and guidelines.
Researchers have made refinements to a technique combining MRI and near-infrared spectroscopy (NIRS) to improve image quality and accuracy in detecting breast cancer. The new design allows for increased coverage of the chest, providing improved visibility for 'hard-to-see' areas, and has shown promising results in clinical trials.
Researchers have successfully used the Cherenkov effect to capture and visualize radiation beams entering or exiting the human body. This breakthrough technology enables doctors to see the dose of radiation to the skin and detect errors in dosage, potentially reducing side effects like skin reactions during breast cancer treatment.
Researchers at VCU Massey Cancer Center are studying how the ACA affects cancer screening in low-income women and employed married women with breast cancer. The study found that Medicaid expansions increased breast and cervical cancer screening, particularly among low-income women, suggesting a positive effect of near-universal coverag...
A new study from Ohio State University Comprehensive Cancer Center found that the quality of cancer stem cells, rather than their quantity, may be associated with better survival rates in patients with HPV-related oral cancers. Researchers discovered that HPV-positive tumors had fewer cancer stem cells, contrary to previous expectations.
A new study found that combining high-dose interleukin-2 therapy with personalized tumor cell-based immunotherapy significantly improves patient survival rates. The treatment approach, which activates patients' immune systems using their own tumor cells, outperforms IL-2 alone in extending survival.
A study by St. Jude Children's Research Hospital found that childhood cancer patients are no more likely to develop post-traumatic stress disorder (PTSD) than their healthy peers. Despite a life-threatening diagnosis, young cancer patients reported benefits from the experience, including greater empathy and closer relationships with fa...
Researchers are developing a new diagnostic technique using infrared light to identify chemical changes in cells that lead to cancer development. The technology has the potential to detect alterations in both cancer and surrounding stromal cells, helping diagnosis and therapy development.
A new approach dubbed SMART has been shown to more than double three-year survival rates for mesothelioma patients treated with radiation therapy followed by surgery. The treatment approach, which involves an accelerated five-day course of intensity-modulated radiation therapy, reduces the risk of recurrence and improves quality of life.
The European Society for Medical Oncology warns that Eastern Europe lacks sufficient data, highlighting the need for a unified system. Despite this, many Western European countries are expected to have enough medical oncologists to meet growing cancer demands by 2020.
Patients treated with IMRT experience fewer side effects and lower cancer-related deaths compared to traditional radiation therapy. The study found that IMRT is a safe and beneficial treatment option for patients with head and neck cancer, with improved survival rates and reduced life-threatening recurrences.
A study found that 88% of participants opted for further investigation even if symptoms carried only a one per cent risk of indicating cancer. Patients cited peace of mind and early detection as main reasons for wanting more timely testing, highlighting the need for NHS guidelines to be revised.
Researchers discovered a genetic signature that implicates key immune system mechanism in driving acute lymphoblastic leukemia, the most common form of childhood cancer. The study found that genomic rearrangement and deletions of DNA segments drive cancer progression.
Researchers developed a nomogram to predict likelihood of overdiagnosis based on age, PSA level, and Gleason score. The tool aims to help patients and clinicians make informed decisions about treatment options.
Researchers have discovered a new drug delivery system that uses nanotechnology to effectively inhibit the growth of lung and head and neck cancer cells. The study found that nano-luteolin, a water-soluble polymer encapsulated form of the antioxidant luteolin, is highly effective in chemoprevention.
Researchers at Ohio State University discovered a seven-gene panel associated with DNA methylation that can identify patients with the best or poorest outcomes in acute myeloid leukemia (AML) treatment. Patients with low scores, indicating few highly expressed genes, had better complete-remission rates and longer survival rates.
The Sandra and Edward Meyer Cancer Center at Weill Cornell Medical College will use precision medicine and cutting-edge approaches to spur breakthroughs in cancer treatment. The center's efforts will be supported by a $75 million gift, which also names the new flagship building.
A study found that 50 years of tobacco control efforts have added nearly 20 years to the life of eight million Americans. The researchers attributed this reduction to the 1964 Surgeon General's report and subsequent tobacco control activities.
Researchers found that targeting molecular profiles of non-small-cell lung cancer with mutated cancer-causing protein KRas is the most effective treatment strategy. The study suggests that combination therapy using approved inhibitors might improve outcomes for patients with wild-type KRas tumors.
Researchers from Rice University and MD Anderson Cancer Center analyzed cancer patients' statistics, finding higher costs associated with complications. The study found that even small increases in hospitalization costs could be substantial, with respiratory failure resulting in a cost increase of over 50% for all cancer resections.
A new cell mechanism has been discovered that drives the spread of breast cancer to other parts of the body. Researchers found that a protein called RON kinase signals tumor cells to become active, reprogramming genes responsible for metastasis. Inhibiting RON turns off this entire program, making it a promising target for therapy.
Researchers have identified two novel BRAF fusions in melanomas previously considered to be negative for molecular targets, suggesting that these tumors may be sensitive to MEK inhibitors. The findings could provide a new treatment option for patients with hard-to-treat melanomas.
A study published in Health Expectations identified key markers of compassion in doctor-patient conversations, including recognition of suffering, emotional resonance, and movement towards addressing suffering. The researchers aim to create a behavioral taxonomy that will guide medical training and education.
A new study from the University of Michigan Comprehensive Cancer Center found that surgery significantly improves survival rates and functional outcomes for patients with advanced oral cavity cancer. In contrast, those who received chemotherapy after initial treatment had poorer results.
Younger women with aggressive tumors and higher recurrence risks are less likely to receive radiotherapy after breast conserving surgery, according to a nationwide database analysis. Factors affecting non-compliance among younger women include family structures and region of residence.
A new analysis found that both real and sham acupuncture may help alleviate breast cancer drug side effects. Patients who received real acupuncture experienced less joint/muscle discomfort and menopausal symptoms compared to those receiving sham acupuncture.
A new analysis found that both real and sham acupuncture treatments alleviate side effects of breast cancer drugs, including hot flashes and joint/muscle pain. Women who received real acupuncture had a greater reduction in symptoms if they were African American.
A new Northwestern Medicine study reveals that leading National Cancer Institute-designated comprehensive cancer centers do not consistently identify and inform patients about their fertility risks or refer them to specialists. Fertility navigators are crucial in bridging the gap between oncology and fertility, but only a third of thes...
Researchers at Ohio State University confirm that ibrutinib targets Bruton's tyrosine kinase (BTK), a critical molecule in chronic lymphocytic leukemia cell growth and proliferation. Inhibiting BTK delayed CLL development and improved overall survival in mouse models.
Researchers found that K-Ras mutations allow cancer cells to survive and invade tissues without normal survival signals. The study suggests that these mutations promote invasion by subverting the mechanism of normal cell death.
A new research study at Cedars-Sinai Medical Center is investigating the predictors, mechanisms for development, and persistence of post-treatment fatigue in breast cancer patients. The study will examine biological, behavioral, and social risk factors to identify women at high risk for fatigue.
A recent study published in BJU International found that radiation therapy used to treat uterine cancer may increase the risk of developing bladder cancer. Patients treated with pelvic radiation therapy had a twice-higher incidence and nearly three times higher death rate from bladder cancer compared to those without radiation.
A Mayo Clinic-led study found that pain drugs used in prostate gland removal may be linked to cancer outcomes, as they can suppress the immune system's ability to fight cancer cells. The research suggests that a specific technique using opioids may reduce the risk of cancer recurrence and mortality.
Death rates for lung cancer, colorectal, breast, and prostate cancers have been declining, driving a reduction in cancer deaths. However, some cancers, including liver and pancreas, saw increased death rates. Comorbid conditions also impact survival, with one-third of patients aged 65+ having multiple medical conditions.
A study of over 4,400 physicians found that those who would personally enroll in hospice care are more likely to discuss it with patients, but delays remain. Despite personal preferences, many physicians do not have timely discussions about end-of-life care with terminally ill cancer patients.
Researchers have identified a clearance system that recognizes and breaks down the oncogenic KRas protein, leading to its degradation. This discovery provides a new avenue for developing targeted therapies for cancer types with KRas mutations.
Researchers found a significant reduction in Medicare spending of $721 annually per patient, with no adverse consequences for survival, through the use of accountable care organizations (ACOs). ACOs led to better management of acute care, resulting in fewer hospital admissions among beneficiaries with prevalent cancer.