Articles tagged with Cancer Patients
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Researchers at Henry Ford Hospital found stereotactic body radiotherapy to be a viable option for elderly patients with localized pancreatic cancer, offering a six-to-seven-month increase in lifespan and minimal side effects. The study also showed that two patients lived nearly two years after treatment.
A study of Stage T1aN0 breast cancer patients found no significant increase in deaths from cardiac disease or secondary malignancies among those receiving external beam radiation therapy (XRT). Women who received XRT had better survival rates and fewer deaths from all causes compared to non-XRT groups.
Researchers at Ohio State University have discovered that high levels of microRNA-31 in primary tumor cells predict lymph node metastasis and poor survival in patients with non-small cell lung cancer. Low expression levels were associated with excellent survival.
A simple two-question survey was found to be as accurate as a nine-question screening test in detecting major depression among cancer patients. The survey, based on the Patient Health Questionnaire, assesses a patient's interest in activities and feelings of hopelessness over the past two weeks.
A large study found that married cancer patients live markedly longer and are more likely to receive appropriate therapy compared to unmarried patients. Social support from spouses plays a critical role in improving outcomes for these patients.
A new study published in CANCER journal found that many newly diagnosed older breast cancer patients experience difficulty with daily tasks. The research suggests that therapy to improve physical function could benefit these patients, particularly African-American women who are four times more likely to have functional disability.
A study published in the Journal of Clinical Oncology found that married patients with cancer live longer than unmarried patients, with cancers diagnosed at an earlier stage. Social support from spouses is thought to be driving this improvement in survival rates.
Researchers found that reducing radiation dose to stem-cell niches surrounding hippocampus preserves memory without increased risk of relapse. This technique, if validated, will help maintain quality of life for brain cancer patients.
A two-item questionnaire, including PHQ-9 and PHQ-2, effectively screened for depression in radiation therapy patients. The study found that these questions were as useful as the entire PHQ-9 in identifying depression, with an area under the curve of approximately 0.83.
Researchers at USC have discovered a novel regulatory factor, UVRAG, that coordinates trafficking of proteins between the endoplasmic reticulum and Golgi apparatus and autophagy. This finding offers a new avenue to investigate anti-cancer agents targeting UVRAG and/or the ER-Golgi pathway.
The ESMO Designated Centres programme has seen a significant increase in new applications, with 37 successful new entrants in 2013. The programme aims to promote integrated oncology and palliative care services for cancer patients and has been highly successful, with over 160 centres recognized globally.
Cancer biologists use a new approach to study human tumors by transplanting them into mice with crippled immune systems. The results show high genomic fidelity between the original tumors and transplanted cancer cells in mice, providing insights into drug resistance. This approach may lead to more precise treatment choices and faster d...
Sherri Graves Smith, a cancer survivor and volunteer, will receive the 2013 Survivor Circle Award from ASTRO. She has dedicated her time and energy to helping others in her community, providing financial assistance and support to cancer patients struggling with daily living essentials.
The Cancer Foundation of Northeast Georgia and the South Georgia Medical Center, Pearlman Cancer Center will each receive $8,000 to provide direct support for their organization's work supporting cancer patients. The grants also aim to raise awareness about the financial challenges faced by cancer patients.
A new marker called isocitrate dehydrogenase (IDH1) has been identified as a non-invasive diagnostic marker for lung cancer, with high sensitivity and specificity in detecting non-small cell lung cancers (NSCLC). IDH1 levels were found to be significantly higher in patients with lung cancer compared to healthy controls.
A new study found that microRNA-486 (miR-486) is a potent tumor-suppressor molecule in lung cancer. It regulates the proliferation and migration of lung-cancer cells and induces programmed cell death.
Researchers propose a new approach called network-based stratification to identify cancer subtypes based on shared genetic networks. This method has immediate clinical value and can help clinicians better match treatment to individual patients, leading to more effective therapies.
Pr. Françoise Meunier has been recognized with the ECCO Lifetime Achievement Award for her dedication to improving cancer survival rates through international multidisciplinary clinical research. Her contributions include promoting EORTC as a major European organization in cancer research and treatment.
A University of Colorado Cancer Center study found that current ALK-positive lung cancer criteria may miss patients who could benefit from crizotinib. The researchers suggest that doctors should re-evaluate borderline or atypical cases, potentially expanding treatment eligibility.
Researchers are identifying genetic biomarkers in patient blood samples to predict aggressive breast cancer progression. Large oncosomes, tumor-derived vesicles, may serve as valuable insights into disease progression.
Researchers identified seven potential candidate genes as targets for melanoma immunotherapy, including cancer-testis genes and melanoma-related genes. The NCI is currently conducting clinical trials using this technology to treat various cancers.
Scientists have developed a new way to analyze archived biopsy samples for exposure to carcinogenic substances, providing insights into the role of environment in cancer risk. The breakthrough enables broader use of stored tissue samples to study human exposure and DNA damage.
A new method uses a combination of techniques to detect genetic variations that initiate colon cancer. The technique achieved high sensitivity and was able to detect APC variations in 41 out of 80 samples, including previously unknown variations.
Dermatomyositis patients with antibodies against NXP-2 and TIF-1γ have a high risk of cancer, according to new tests developed by researchers. The assays detect these specific proteins in patient blood samples, helping clinicians identify those at highest cancer risk.
A study found wait times for colorectal cancer operations at VA hospitals rose to 32 days, but researchers believe longer waits may be due to improved care and outcomes. The study suggests that more careful care is worth the wait, even if it means delayed treatment.
A study of healthy women found that describing preinvasive breast cancer as a high-risk condition rather than cancer leads to more women opting for nonsurgical treatments. The study's results suggest that the terminology used to describe DCIS can significantly impact patients' perceptions of treatment alternatives.
A Penn Medicine study reveals that survivorship care plans, such as the online LIVESTRONG Care Plan, fill a knowledge gap for cancer patients and improve health outcomes. The plans provide essential information on follow-up screenings, late effects of treatment, and lifestyle changes.
A Mayo Clinic study found that patients with glioblastoma who died in 2010, after the FDA approved bevacizumab, lived significantly longer than those who died in 2008. The treatment strategy involving bevacizumab prolonged survival at a population level.
A large study found increasing rates of preventable adverse events after major cancer surgery, such as blood clots and infections, but decreasing overall mortality rates in the US. Despite improvements in managing these events, experts emphasize the need for better prevention strategies to reduce complications.
A phase I clinical trial shows that diffuse, large B-cell lymphomas resistant to chemotherapy can be reprogrammed to respond using the drug azacitidine. Patients whose tumors do not respond to standard therapies are being treated with a combination of approaches, including high-dose chemotherapy and stem cell transplant.
Researchers found four biomarkers in microRNAs that accurately determine malignancy and predict patient outcomes in urinary bladder cancer. Two miRNAs correlated with overall survival time, providing potential prognostic capabilities.
Melanoma patients with a BRAF gene mutation may be at risk of developing secondary cancers due to activated tumor growth pathways. Researchers suggest combining BRAF-inhibitor therapy with other inhibitors to prevent paradoxical activation and emergence of secondary malignancies.
A study found that prostate cancer aggressiveness is established at tumor formation and does not change over time. The proportion of patients diagnosed with advanced-stage cancers decreased by more than six-fold after widespread PSA screening, while high Gleason grade cancers remained stable.
The NIH awards $17 million for research projects exploring the emerging field of extracellular RNA communication. Scientists will investigate exRNA's role in diseases, develop biomarkers, and create new treatments. The goal is to unlock exRNA's potential for diagnostics and therapeutics.
A study published in Current Oncology has confirmed an epidemic of HPV-related tonsillar cancer in Canada, with a significant increase in cases over the past few decades. The research found that young non-smokers are most commonly affected, and treatment has evolved to include concurrent chemotherapy and radiation.
A new analysis reveals carbon ion radiotherapy controls cancer growth and prolongs survival in patients with spinal tumors, offering a promising alternative to surgery. The treatment has minimal impact on healthy tissues and potential to preserve quality of life.
Metabolic fingerprinting looks at metabolite levels in blood, urine, or tissue to analyze tumor development and growth. This technique can improve diagnosis accuracy alongside existing imaging methods.
Researchers created a stratified risk score to predict patient prognosis, finding that age, race, and stage of cancer significantly impact survival rates. The score separates patients into groups with varying 5-year relative survival rates, aiding doctors and researchers in designing treatment strategies.
A new set of guidelines aims to reduce radical surgery and extend survival time for men with penile cancer, providing better quality of life. The guidelines offer various treatment options, including non-radical surgeries, laser therapy, radiation therapy, and radiochemotherapy.
Researchers found that a specific pattern in tumor pathology is strongly associated with cancer recurrence. Patients with this pattern are more likely to benefit from lobectomy and have a 75% lower risk of recurrence. The study may lead to new technology to precisely identify tumors with this pattern before surgery.
Aristolochic acid, a plant compound in herbal remedies, causes upper urinary tract cancers through a distinct DNA mutational signature. The Johns Hopkins and Stony Brook study used whole-exome sequencing to identify this signature, which was found in 19 Taiwanese cancer patients exposed to the toxin.
A new study from Huntsman Cancer Institute suggests that family members of children with cancer may be at higher risk of developing childhood cancer, depending on their family medical history. The research recommends collecting three generations of family medical history for all newly diagnosed pediatric cancer patients.
Scientists have discovered a new biomarker that predicts how well cancer patients respond to cancer drugs. The biomarker, linked to PRL-3 protein levels, identifies patients who are most likely to benefit from existing anti-cancer treatments, reducing healthcare costs and potentially saving lives.
A new study reveals that certain patient groups feel unmet needs for greater involvement in cancer treatment decisions. Younger patients and those with specific rare types of cancer want more input in the decision-making process. The research emphasizes the importance of shared-decision making policies to address these disparities.
The Louisiana Tumor Registry has been awarded a contract to continue its work as a SEER Program-designated cancer registry, collecting cancer incidence and survival data from 28% of the US population. The funding will support cancer research, including prevention, early detection, treatment, and survivorship studies.
Researchers at Fred Hutchinson Cancer Center are pioneering a new approach to harness the power of the adaptive immune system to control cancer. They are using high-throughput technology and large-scale data mining to identify potential immune targets and verify their immunogenicity.
A portable diagnostic device developed by Chinese researchers can travel to patients anywhere in the world, providing an opportunity for early cancer detection. The device uses microfluidics technology and is designed to be low-cost, easy-to-use, and power-independent.
Researchers found that women with atypical lobular hyperplasia (ALH) and lobular carcinoma in situ (LCIS) can avoid surgery if radiologist and pathologist findings are concordant. Yearly mammograms, MRI, or ultrasound as second-line screening tools may suffice.
A scientific panel recommends personalized strategies to reduce cancer overtreatment by classifying indolent tumors and improving screening strategies. The goal is to detect consequential cancer while avoiding inconsequential disease.
A new study published in JAMA Internal Medicine found that decision aids increased men's knowledge and reduced conflict about PSA screening, but did not impact their decisions. The tools were equally effective in improving knowledge and reducing decisional conflict.
New study reveals stable survival rates for HIV-associated lymphoma patients during the antiretroviral therapy era. Despite increased incidence and changing demographics, recent diagnosis years are not associated with decreased mortality. The study highlights an ongoing need to improve treatments for this challenging population.
Researchers discovered a function of PTEN that helps explain why certain therapies fail in many cancer patients. The finding increases understanding of molecular mechanisms and provides clues for individualizing therapy for patients with PTEN-deficient tumors.
Scientists at Ohio State University have identified two regions on the HER1/EGFR receptor as potential targets for peptide-based cancer vaccines and therapeutic agents. These peptides show promise in inhibiting tumor growth in breast and lung cancer models.
A Swedish data-sharing campaign led to a significant decrease in unnecessary medical tests for low-risk prostate cancer patients. The study suggests that curtailing unneeded medical tests is achievable and offers insights into the importance of implementing guidelines and providing feedback to practitioners.
A new study found that only 40% of young female cancer patients were happy with the way their doctors discussed fertility preservation options. The study suggests a need to rethink how fertility issues are discussed with young people diagnosed with cancer, both in terms of timing and content.
Researchers found that approximately 13% of smokers used e-cigarettes as a means of quitting, with younger smokers more likely to use them. E-cigarette users were also found to be more motivated to quit smoking compared to those who tried other cessation aids.
Researchers have found that elevated levels of a receptor protein called Ret are associated with lower survival rates in breast cancer patients. Inhibiting this protein may be a promising approach to treating the disease.
Prehabilitation interventions, including physical and psychological support, can reduce treatment-related complications, improve physical and mental health outcomes, and increase treatment options. Benefits include lower complication rates, reduced hospital readmissions, and improved healthcare costs.
Researchers have developed a promising new cancer treatment, PAC-1, which targets a cellular enzyme to spur cancer cells to self-destruct. The compound has shown safe and anti-cancer effects in cell culture, mouse models, and pet dogs with spontaneously occurring cancers.
Researchers developed an 'intelligent knife' that can identify cancerous tissues during surgery, providing instant results. The technology, called iKnife, was tested on 91 patients and showed 100% accurate diagnosis, potentially reducing tumour recurrence rates and improving patient outcomes.