Articles tagged with Cancer Patients
A new study defines 'sudden exhaustion syndrome' as a distinct condition affecting cancer patients undergoing treatment, characterized by intense and prolonged fatigue. The research aims to enhance recognition and management of this often-overlooked symptom among oncology professionals.
A study published in Health Psychology found that endometrial cancer survivors who had higher daily self-efficacy tended to exercise longer and more intensively. This is significant because exercise is a crucial aspect of cancer survivorship, particularly for those who are overweight or obese.
UT MD Anderson scientists found that a common substance in cancer vaccines facilitates a buildup of T cells at the vaccination site, summoning more T cells and causing lesions. Switching to saline adjuvant reversed the effect, allowing T cells to target tumors. A new clinical trial is expected to test this concept.
Patients with advanced head and neck cancers have higher survival rates when treated at high-volume hospitals and dedicated cancer centers. Despite this, the proportion of patients who received multimodality therapy was similar between low- and high-volume hospitals.
Researchers found that patients with metastatic gastric cancer who underwent both surgery and radiation had better survival rates than those receiving one or no treatment. Radiation therapy also showed promise in reducing symptoms such as pain, obstruction, and bleeding from gastric tumors.
Women with Lynch Syndrome have a 50-60% lifetime risk of developing colorectal cancer, but an 11% risk of breast cancer, 11% risk of kidney cancer, and 9% risk of bladder cancer. This study expands the spectrum of cancers associated with Lynch Syndrome.
A recent study by Ohio State University researchers has identified specific small molecules in the blood that can accurately measure damage to the body after ionizing radiation exposure. The findings suggest that these microRNA markers could help doctors identify individuals at risk for acute radiation syndrome and plan personalized ra...
A study by Rutgers University behavioral neuroscientist Tracey Shors found that prolonged chemotherapy decreases the development of new brain cells, disrupting ongoing brain rhythms necessary for learning. This can lead to cognitive problems such as short-term memory loss and disordered thinking in cancer patients.
A recent study by Professor Hermann Brenner and colleagues found that smoking cessation in older adults significantly reduces the risk of heart attacks and strokes. Within five years of quitting, smokers experience a reduction of over 40% in cardiovascular disease risk compared to non-smokers.
A growing health threat across low-income and middle-income countries, childhood cancer claims over 100,000 lives of children under 15 annually. Poor treatment access, lack of awareness, and limited healthcare infrastructure hinder effective care, emphasizing the need for investment in healthcare systems and capacity.
A six-session program addressing cognitive, physical, emotional, social and spiritual well-being significantly improved patients' quality-of-life measures. Despite the benefits for cancer patients, caregivers showed no improvement in quality-of-life measures during treatment.
Researchers at St. Michael's Hospital have developed a shorter version of the Patient-Generated Subjective Global Assessment (PG-SGA) tool to screen cancer patients for malnutrition. The abPG-SGA tool was found to be effective in identifying malnourished patients and improving patient outcomes.
A study published in Blood found that certain chemotherapies increase a patient's risk of developing therapy-related acute myeloid leukemia (tAML), a rare but frequently fatal condition. The risk varies by type of cancer and year of diagnosis, with some patients facing higher risks more than 10 years after their initial diagnosis.
Researchers discover pairing Avastin with dasatinib can stop lethal spread of aggressive brain cancer glioblastoma multiforme. The combination reduces tumor growth and blocks further spread by inhibiting protein migration.
A study published in Journal of Pediatric Oncology Nursing found that discomfort with tube feeding is the main reason families prefer IV nutrition. Tube feeding is associated with better gut function and lower infection rates, but perceived discomfort leads to a preference for IV feeding.
Researchers found that selumetinib increased iodine uptake in tumors resistant to radioiodine therapy, allowing some patients to undergo treatment. The study shows promise for RAS-mutant disease and paves the way for a larger clinical trial.
A phase II clinical trial shows that selumetinib, a targeted therapy, can halt growth or shrink tumors in 15% of patients with recurrent low-grade ovarian cancer. The two-year overall survival rate is 55%, and the median overall survival has not been reached due to high patient survival rates.
Researchers warn that molecularly targeted therapies may stunt growth, delay puberty, or increase the risk of diabetes in children. The lack of long-term data on these treatments raises concerns about their use in pediatric patients. Experts recommend using these drugs only in clinical trials to monitor side effects.
A new study published in Radiology found that CT scans are associated with a significantly lower risk of death than radiation-induced cancer in young adults. The study analyzed imaging records of patients 18 to 35 years old who underwent chest or abdominopelvic CT exams between 2003 and 2007.
A study published in the Journal of General Internal Medicine found that patients who use a web-based risk appraisal tool are more likely to have important family history documented, leading to better cancer screening and reduced mortality. The tool may help increase communication between physicians and patients about their risk factors.
The National Institutes of Health (NIH) emphasizes the importance of genomic knowledge for nursing care, highlighting its relevance to advancing patient care. Genomic studies published in the Journal of Nursing Scholarship provide insights on genetic applications in nursing practice, including cancer risk assessment and prevention.
A recent book chapter reviews psilocybin's potential to alleviate psychological distress in cancer patients, including anxiety, depression, and existential distress. The hallucinogen treatment model has been shown to induce mystical or spiritual experiences, leading to improved psychological, spiritual, and existential well-being.
Research found that a large majority of head and neck cancers have deregulated PI3K/AKT/mTOR pathway, but this doesn't necessarily mean the tumor is dependent on it for survival. The study used tumor explant model to distinguish driver mutations from passenger mutations, which could help stratify patients for response to mTOR inhibitors.
Researchers from MD Anderson Cancer Center found that qigong reduces depressive symptoms and improves quality of life in women undergoing radiotherapy for breast cancer. The study suggests that qigong may prevent a delayed symptom burden and expedite recovery, especially for women with elevated depressive symptoms.
A recent study found that stress can accelerate prostate cancer development in mice, with adrenaline blocking cancer cell death. Conversely, drugs that inhibited adrenaline signaling ablated the effect of stress on prostate cancer. This suggests that beta-blockers could enhance the effectiveness of anti-cancer therapies.
Researchers at BRIC, University of Copenhagen, have found that blocking the enzyme Lysyl Oxidase (LOX) can significantly decrease metastasis in breast cancer models. This breakthrough suggests a new approach to prevent tumour microenvironment scarring and enhance patient outcomes.
Researchers found that lung and head and neck cancer patients who quit smoking before surgery had significantly lower relapse rates compared to those who smoked during the week prior to surgery. The study also identified factors such as high fears regarding cancer recurrence, depression, and low belief in quitting abilities as predicto...
A University of Colorado study reveals that lung and GI cancer patients are more prone to E. coli and Klebsiella pneumoniae infections, particularly after aminopenicillin treatment. This knowledge can inform targeted antibiotic therapy before complications arise.
Researchers discover protein OTUD7B, which regulates TRAF3's destruction and controls NF-kB pathway implicated in autoimmune diseases and cancer. Cells with intact OTUD7B suppress non-canonical NF-kB signaling, leading to increased lymphoid cell growth and hyper-responsiveness to antigens.
A new multiple gene expression profile test can predict the presence of harmful BRCA1 or BRCA2 mutations in otherwise healthy women. The test showed a sensitivity of 95% and specificity of 88%, and has the potential to replace expensive sequencing tests, making it an affordable option for high-risk carriers.
A multi-center Phase III clinical trial demonstrates that Abraxane plus gemcitabine extends survival of late-stage pancreatic cancer patients compared to standard treatment. The study showed a 59 percent increase in one-year median survival rates and a doubling of two-year survival to 9%.
A new model developed by scientists can predict which patients with colorectal cancer will respond to chemotherapy. The model measures the stress required for a cancer cell to die without harming healthy tissue, and has been shown to robustly predict patient outcomes.
Researchers identified a genetic marker in over 300 women with breast cancer, finding that those with this marker were more likely to experience recurrence. This breakthrough could enable doctors to tailor treatment strategies for high-risk patients based on their unique genetic profiles.
Researchers at Michigan Medicine have discovered a genetic anomaly that could improve diagnosis and treatment of rare solitary fibrous tumors. The NAB2-STAT6 gene fusion was found in every tumor sample analyzed, providing a potential target for therapies.
Research reveals that a gene switch in the liver is responsible for lowering blood fat levels in cancer patients, leading to dramatic weight loss. The study found that silencing this gene switch in the liver can restore normal lipid levels and muscle mass.
A new study published in Cancer found that smoking intensity affects the course of bladder cancer, with more aggressive and deadly disease developing in those who smoke intensely. A panel of nine molecular markers can predict which cases are at highest risk for a fatal outcome.
A gene called NEK2 promotes drug resistance in cancer, leading to faster growth and poorer patient outcomes. The finding may improve diagnostic and prognostic tools for cancer care.
The American Cancer Society recommends low-dose computed tomography (CT) screening for patients aged 55-74 with a 30-pack-year smoking history. A thorough discussion of benefits, limitations, and risks is essential before screening. Screening can reduce lung cancer mortality in high-risk groups.
A Michigan State University study found that many cancer patients struggle to follow complex chemo prescriptions, leading to poor adherence and reduced treatment efficacy. The researchers suggest an automated calling system could help patients take their drugs properly.
The UCSF Helen Diller Family Comprehensive Cancer Center has received a $36 million grant from the National Cancer Institute to fund its research programs and clinical trials. The center's excellence in laboratory, clinical, and population-based research was recognized by the NCI.
A high-fiber diet, rich in inositol hexaphosphate (IP6), can control prostate cancer progression by inhibiting tumor growth and slowing glucose metabolism. Researchers found that IP6 reduced tumor volumes and slowed glucose metabolism in prostate cancer models.
Researchers found that microscopic hematuria does not necessarily indicate cancer, and patients with this condition may avoid unnecessary tests. A new model, the Hematuria Risk Index, predicts renal and bladder cancer risk, reducing unnecessary work-ups.
A recent study published in Mayo Clinic Proceedings found that microscopic hematuria is an unreliable indicator of urinary tract malignant tumors. The study developed a Hematuria Risk Index to predict cancer risk, identifying low-risk patients who may not need further evaluation and reducing unnecessary evaluations.
A large-scale Swedish study has found that oesophageal cancer patients who undergo surgery by high-volume surgeons have a significantly lower long-term mortality rate. The study's main finding is that centralization to fewer surgeons results in better survival after esophageal cancer surgery.
The University of Kentucky's Markey Cancer Center will continue the Jin Shin Jyutsu program in 2013 thanks to a $25,000 grant. The program, which uses ancient touch therapy, has shown significant improvement in pain, stress, and nausea for patients.
Researchers have found that commonly used algorithms for identifying patients with recurrent cancer are flawed and often mislead researchers. These algorithms rely on billing codes or secondary tumors to identify patients, but this approach can be inaccurate, as it may not distinguish between new cancers and recurrences.
Research found that low iron levels accelerate H. pylori-induced carcinogenesis in rodents and humans, increasing the risk of gastric cancer. Iron deficiency is associated with more virulent H. pylori strains and greater inflammation, highlighting the importance of iron levels in identifying high-risk patients.
A retrospective analysis of over 36,000 patients with colon cancer found that those with early stage disease and diabetes or high blood pressure have a greater risk for cancer return and death compared to patients without these conditions. High lipid levels were also found to be protective against recurrence.
A new study highlights the importance of considering immediate health risks when weighing benefits and potential future radiation-induced cancer risks. The researchers found that for patients with testicular cancer undergoing CT surveillance, the near-term risk of death from the condition was more significant than lifetime cancer risk.
Scientists have developed a new device that captures and preserves cancer cells circulating in the bloodstream, allowing for non-invasive diagnosis and insight into cancer spread. The technology could enable doctors to detect tumor cells earlier and provide valuable information on how cancer spreads throughout the body.
A new analysis suggests that individuals with Lynch syndrome, who have a high risk of developing colorectal and other cancers, may lower their risk by adopting an eating pattern low in snack foods. The study found that those with higher intakes of snack foods were twice as likely to develop precancerous lesions.
A Phase 2 clinical trial of ibrutinib in relapsed or refractory mantle cell lymphoma reported a 68% overall response rate and 22% complete remission rate, with few side effects. The drug's efficacy was consistent across different patient populations, making it a promising treatment option for patients with this aggressive disease.
A recent study found that rural US residents are less likely to follow colorectal cancer screening guidelines due to the time required for travel and limited access to healthcare. The researchers also noted that lack of health insurance and primary care provider shortages contribute to this disparity.
A new screening approach identified potential anticancer drug combinations that target RAS and BRAF mutations in melanoma. The study found that pairing cholesterol-reducing drugs with cyclin-dependent kinase inhibitors showed efficacy against RAS-driven melanomas.
A new Dream Team project, Immunologic Checkpoint Blockade and Adoptive Cell Transfer in Cancer Therapy, aims to expand and optimize combinations of two novel immunotherapies. The team will unite laboratory and clinical efforts to develop durable responses in patients suffering from various types of cancer.
A new study suggests that age affects treatment outcomes for chronic lymphocytic leukemia (CLL) patients. Researchers found that optimal therapy differs between younger and older patients, with CD20 antibody therapies showing promise as front-line treatment for all CLL patients regardless of age.
Researchers discovered that FAIM can affect cancer cell proliferation and silencing its expression destroys myeloma cells. Higher levels of FAIM correlate with poorer survival outcomes, making it a useful biomarker for multiple myeloma patients.
Researchers found that a weekly dose of the targeted drug inotuzumab ozogamicin reduces side effects and maintains its effectiveness against acute lymphocytic leukemia (ALL) in patients. The treatment showed an overall response rate of 57% with manageable toxicities.
Researchers identified microRNAs associated with oligometastatic progression, which differ from those associated with widespread metastatic disease. These findings suggest a biological basis for oligometastasis and potential use in identifying patients suitable for curative interventions.
A Phase 2 clinical trial found that combining ibrutinib and rituximab produced profound responses in high-risk CLL patients with minimal side effects. Researchers hope to further develop the treatment for this aggressive form of leukemia.