Articles tagged with Cancer Patients
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A study of 125,126 Swedish citizens with type 2 diabetes found an increased risk of 24 types of cancer, with the highest rates for pancreatic and liver cell cancers. The researchers also discovered a lower risk of prostate cancer among diabetics with a family history of the disease.
A new surgical procedure called hyperthermic intraperitoneal chemotherapy (HIPEC) has been shown to increase the survival of children with desmoplastic small round cell tumor (DSRCT), a rare and aggressive cancer. Patients who received HIPEC had a 3-year survival rate of 71%, compared to 26% for those who received only standard treatment.
Researchers found eGFR to be equally valuable as Ccr for assessing preoperative renal function in gastric cancer patients, with significant correlations between postoperative sCr and both eGFR and Ccr. The study suggests eGFR may replace Ccr in clinical practice due to its clear advantages.
Researchers at Henry Ford Hospital found that exercise programs like ExCITE improve quality of life and reduce fatigue in breast and prostate cancer patients. The study, which followed patients for one year after treatment completion, also showed benefits in physical and psychological well-being.
A Northwestern University study found that brain cancer patients with malignant gliomas tend to overestimate their quality of life compared to their caregivers. The research suggests that caregivers play a crucial role in providing a more accurate assessment of the patient's well-being.
Results from an Advanced Therapy Access Program demonstrate oncolytic viruses' ability to mediate anti-tumor immunity in humans. The therapy shows strong efficacy against solid tumor cancers, with a clinical benefit rate of 47% and favorable safety profile.
A recent study found that most patients with localized papillary thyroid cancer can expect favorable outcomes without treatment. The 20-year survival rate for these patients is estimated to be around 97%, similar to those who received treatment. Clinicians and patients can feel comfortable considering observation as an option.
Researchers at Thomas Jefferson University have identified a protein, IGF-IR, that regulates motility and invasion of bladder cancer cells. This finding offers a novel molecular target for treating patients with aggressive bladder cancer and may also serve as a tumor biomarker for diagnosis.
Researchers found that minor adjustments to estrogen receptor alpha and p53 genes can lead to precancerous changes in breast tissue. Testing healthy women for these gene variations may help predict future breast cancer risk.
A clinical panel recommends that patients' blood pressure should be closely monitored and controlled before starting angiogenesis inhibitors for cancer treatment. Treating a patient's hypertension before treatment begins and maintaining blood pressure below 140/90 mmHg can help control this side effect.
A new U-M study shows that advanced radiation techniques can treat head and neck cancer effectively while reducing long-term swallowing complications. The study found that up to 88% of patients were cancer-free after three years, with only one patient still requiring a feeding tube.
A study presented at the ARRS 2010 Annual Meeting found that FDG-PET/CT accurately confirmed a suspected colorectal cancer recurrence in 40 out of 71 patients. This early detection enables improved treatment planning and targeted patient care for those with recurrent colorectal cancer.
Researchers at Mayo Clinic are testing new endoscopic optics to detect precancerous polyps and micrometastasis. The pCLE system shows the highest accuracy yet in detecting small polyps, with a specificity of 100%. This technology has the potential to perform virtual biopsies, reducing unnecessary procedures.
Patients who undergo gastric cancer surgery followed by chemotherapy have a lower risk of death and improved disease-free survival compared to those who receive surgery alone. The analysis found an 18% reduction in the risk of death and improved overall survival with chemotherapy.
A study finds that cancer risk in kidney transplant recipients is similar across different immunosuppressive medications, suggesting no single medication is to blame. Patient characteristics such as age and eye color are associated with increased cancer risk.
A new method has been developed to predict which women with DCIS are at high risk of developing more invasive tumors. The study found that two factors - the method of detection and biomarker expression - can identify patients who are most likely to develop invasive cancer within eight years.
A study by Duke University Medical Center found that imaging costs rose faster than overall cancer care for Medicare patients. The use of PET scans increased significantly, with a mean annual growth rate of 36-53% across six cancer types.
The use and costs of diagnostic imaging for Medicare patients with cancer increased substantially between 1999 and 2006. PET scans saw the largest increase, accompanied by a reduction in conventional nuclear medicine tests and stabilized CT scans.
Researchers at Michigan Medicine found that levels of a key type of immune cell can predict which head and neck cancer tumors are most likely to respond to chemotherapy and radiation. The study suggests a way to target treatments to avoid unnecessary side effects, with potential benefits for HPV-negative patients.
The study found a significantly higher incidence of MDS among seniors, with alarming rates of complications such as heart attacks, diabetes, and sepsis. The disease also proved to be costly to treat, with median Medicare bills exceeding $16,000
The ERCC1 Analysis measures ERCC1 levels in cells to predict response to cisplatin-based chemotherapy, which is considered the standard of care for advanced NSCLC. Studies have shown that low expression levels of ERCC1 are related to a better response and survival benefit from adjuvant cisplatin-based chemotherapy.
Researchers found that men with multiple affected relatives have a substantially increased risk of developing prostate cancer. The study suggests that doctors should urgently recommend early detection screenings for men with several affected relatives, particularly if they have been diagnosed at a young age.
Researchers identify a mechanism to turn developmental genes on and off as an embryo matures, involving the SUMO/SENP2 system. The study provides new insights into epigenetic control and its role in development, cancer, and neurological diseases.
Researchers have identified three new targets for potential treatment of Ewing's sarcoma, a genetic exchange between chromosomes that results in a fused gene. Additionally, two small molecules have been found to prevent or treat the spread of osteosarcoma, a very aggressive cancer.
Researchers found that metformin decreases insulin levels and inhibits tumor growth in mice exposed to tobacco carcinogens. Metformin reduced lung tumor burden by 40-72% in treated mice.
A new study from Fox Chase Cancer Center suggests that levels of ERCC1 offer a predictive marker of survival in squamous carcinoma of the head and neck. Low ERCC1 levels were associated with increased survival from adjuvant therapy, providing support for personalized medicine in these cancers.
Researchers at UAB Comprehensive Cancer Center discovered four microRNA biomarkers that predict patient survival in colorectal cancer, with differences in outcomes between Caucasian and African-American patients.
A large study found that consuming well-done meat increases the likelihood of developing bladder cancer, especially in people with genetic variants. The risk was higher for those who ate high amounts of red meat and had unfavorable genotypes in the HCA metabolism pathway.
A Phase I clinical trial demonstrated early signs of a strong safety profile and clinical activity for BBI608, a first-in-class cancer cell stemness inhibitor. Nine patients achieved stable disease for at least two months with early signs of tumor regression.
Researchers at Georgetown Lombardi Comprehensive Cancer Center found that a high-fat diet during pregnancy increases breast cancer risk not only in daughters but also in their female and male offspring's daughters. The study suggests that pregnant mothers should eat well-balanced diets to potentially reduce the risk of breast cancer in...
Patient advocates and researchers at Vanderbilt Ingram Cancer Center presented an interactive game show on cancer research to increase awareness, particularly of clinical trials. The event resulted in a 20% increase in participants' knowledge and high engagement rates.
A study by researchers at the University of Texas M.D. Anderson Cancer Center has identified a potential new therapy for brain tumors by analyzing DNA methylation patterns. The discovery may help identify patients with more favorable outcomes and offer a targeted treatment approach.
A TGen and VARI program is studying naturally occurring cancers in dogs to better understand the causes of disease and develop new treatments. The goal is to translate knowledge into therapeutics that can help both humans and animals, with a focus on rare sarcomas and osteosarcoma.
A new multicenter study has found that MDV3100 is safe and effective for patients with castration-resistant prostate cancer. The drug slowed tumor growth, reduced PSA levels, and stabilized disease progression, offering new hope for patients with limited treatment options.
A study found that terminal cancer patients spend most of their remaining lifespan on radiotherapy, but only 26% experience palliation or pain reduction. The authors conclude that radiotherapy is not tailored to individual patient needs, leading to excessive and often uncompleted treatments.
College women are more likely to be vaccinated against HPV if their mothers communicate with them about sex and approve of the vaccine. Young women who thought their mothers would approve were more interested in getting vaccinated, while those whose mothers discussed values in relation to sex showed less interest.
The Southwest Oncology Group's operating grants have been renewed for six years, with a total expected to exceed $120 million over the period. The renewal supports comparative effectiveness research and will primarily fund member institutions nationwide.
Researchers at the University of Texas M. D. Anderson Cancer Center have developed a new way to predict prognosis in pediatric leukemia patients using a common complete blood count test. The study found that combining the minimal residual disease indicator and absolute lymphocyte count provides better results than MRD alone, identifyin...
Singapore's A*STAR is collaborating with Italy's Siena Biotech to develop targeted therapies for gastric cancer, leukemia, and osteoporosis. The partnership aims to leverage advanced molecular biology and antibody engineering techniques to create novel treatments.
A new oral anti-cancer drug, vorinostat, is safe to combine with short-term palliative radiotherapy in patients with advanced pelvic cancer. The therapy may enhance the effect of radiotherapy and could become a component of long-term curative treatment. Patients showed tumor response and reduced side effects when treated with vorinostat.
A new study reveals that childhood cancer survivors may experience a significant decrease in life expectancy, with some facing a 10-17 year reduction. The research suggests that recent advancements in treatments and closer monitoring may improve long-term outcomes for these patients.
Dr. Von Hoff, TGen's Physician-in-Chief, has been recognized with the David A. Karnofsky Memorial Award and Lecture at ASCO's Annual Meeting. He is a renowned physician-scientist who has contributed to developing numerous anticancer agents.
A new study found that ghrelin improved appetite and food intake in gastric cancer patients who had part or all of their stomach removed. Body weight loss was significantly lower in the ghrelin group compared to the placebo group, indicating a potential benefit for these patients.
People with diabetes undergoing cancer surgery are at a higher risk of death in the month following their operations. The study, led by Johns Hopkins researchers, found that newly diagnosed cancer patients with Type 2 diabetes have a 50% greater risk of mortality after surgery, particularly for colorectal and esophageal tumors.
A $3.8 million grant aims to address cultural barriers and biases limiting minority participation in cancer clinical trials. A patient navigation model is being established to provide assistance and support to patients considering or enrolled in trials.
Canadian researchers have identified a previously hidden channel in humans that allows anti-cancer agents like Bleomycin to target leukemia cells. This discovery may revolutionize treatment for acute myeloid leukemia, a cancer affecting white blood cells.
Research suggests locoregional recurrence after long disease-free interval is associated with distant disease rather than cause. Patients with recurrence have four times higher risk of metastases and eight times higher risk of dying compared to those without recurrence.
A randomized trial found that octreotide acetate did not reduce the incidence or severity of diarrhea in patients with anorectal cancer. The study included 215 patients who received either a placebo or long-acting octreotide before and during radiation therapy, but no significant differences were observed between groups.
A new study by Dartmouth researchers found that patients treated at similar, specialized cancer care institutions experienced equal mortality rates regardless of race. This study suggests a substantial decrease in death rates among African Americans when treated at these institutions.
African American patients with similar treatment settings as white counterparts show reduced mortality rates, highlighting the impact of institutional factors on cancer outcomes. The study suggests that where patients receive care may partly explain observed racial disparities.
UAB researchers emphasize the need for community-driven approaches to reduce cancer disparities, citing limited access to care and differences in healthy behaviors as contributing factors. They highlight successful programs that have eliminated disparities in screenings for certain cancers and advocate for engaging diverse populations ...
A nurse researcher has settled a common cancer concern by discovering that routine advice on skin care was rooted in myth instead of scientific evidence. Her findings, published in the Clinical Journal of Oncology Nursing, found no evidence to support a four-hour restriction on lotions before radiation therapy.
A study by University of Texas M.D. Anderson Cancer Center reveals that US cancer centers have varying levels of palliative care programs and services, with NCI-designated centers having more comprehensive programs. Despite the differences, there is strong support for integrating palliative care into oncology care.
A study found significant disparities in palliative care services across US cancer centers, with NCI-designated centers offering more comprehensive programs. The researchers identified barriers such as poor reimbursement and limited institutional resources hindering the delivery of high-quality palliative care.
A content analysis found that media reports tend to focus on aggressive treatments and survival rates, neglecting discussions of death, palliative care, and adverse events. This study highlights the need for a more balanced approach in cancer news coverage.
A RAND-UCLA study found that patients with stage III colon cancer receive chemotherapy at a lower rate than recommended, with older patients being less likely to receive the strongest treatment. Despite this, older patients do not experience more adverse outcomes compared to younger patients.
Peter K. Vogt's groundbreaking discovery of src, the first cancer-causing gene, has profoundly changed biology and medicine. His research has yielded several important targets in cancer therapy.
Two studies reveal a significant increase in non-melanoma skin cancers in the US, with over 13 million Americans affected by 2007. The disease is associated with substantial illness and cost, and continues to be a major public health concern.
A study found that nearly half of dying cancer patients visit the emergency department in the last two weeks of life, often due to uncontrolled symptoms. Effective palliative care can help manage these symptoms and reduce visits to the emergency department.
A new clinical trial at the Virginia G. Piper Cancer Center uses molecular profiling to identify specific treatments for refractory breast cancer. The trial aims to keep cancer under control for longer periods and potentially shrink tumors.