Articles tagged with Disease Control
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A study of over 153,000 US adults found that only three percent maintain a healthy lifestyle with all four characteristics: nonsmoking, healthy weight, and regular physical activity. Most Americans fail to meet even one of these key habits, highlighting the need for comprehensive prevention activities.
A malaria vaccine, RTS, S/AS02, has shown substantial protection in trials, with 30% and 58% effectiveness rates. However, an efficacious vaccine is not yet available for widespread use due to funding and organizational challenges. Experts predict a decade-long timeline for the development of a viable vaccine.
A recent study published in the American Journal of Preventive Medicine reveals a concerning trend: alcohol-impaired driving episodes are increasing, with four out of five cases linked to binge drinking. The researchers stress that new strategies are needed to address this issue, including reducing binge drinking and implementing deter...
Leishmaniasis, a fatal disease affecting 1.5 million people worldwide, will be controlled through paromomycin with the goal of delivering treatment for under $10. The Institute for OneWorld Health aims to change generations of families devastated by VL.
Researchers identify renalase as a novel protein regulating cardiac function and blood pressure. WNK1/4 interaction is also crucial for controlling human blood pressure and familial hyperkalemic hypertension (FHHt) risk.
Researchers at Yale University have developed a method to remotely control fly behavior using laser light, demonstrating a direct link between specific neurons and behaviors. The technique involves genetically engineered 'phototriggers' that respond to light pulses, allowing for non-invasive control of neural activity.
Critics argue that outsourcing of hospital cleaning staff may contribute to increased deaths from MRSA, but hand hygiene and glove use are key to controlling transmission. The Lancet suggests that UK policies focus on the wrong issue, prioritizing housekeeping programmes over essential infection control practices.
A recent study published in PLOS Medicine found that uric acid levels are unlikely to be a major determinant of coronary heart disease. The research analyzed data from over 9,400 cases of CHD and 155,000 controls, concluding that improving diet, losing weight, and controlling blood pressure may help reduce the risk of CHD.
A review of 29 studies found that 19.6% of chronic fatigue syndrome patients improved with inactive treatments, lower than expected figures for other conditions. Behavioral therapy and graded exercise therapy show benefits, but high patient expectations and a perceived physical origin may hinder treatment outcomes.
Researchers at Imperial College London have solved the structure of the Foot-and-Mouth Disease Virus enzyme, revealing its atomic details and potential target for anti-viral drugs. The discovery could lead to the development of a vaccine that can be administered quickly to control outbreaks.
Researchers identified genes in yeast that cooperate to prevent DNA mutations and genome rearrangements caused by oxygen radicals. This discovery may lead to new strategies for alleviating clinical symptoms of human diseases associated with genetic deficiencies of DNA damage responses, including potential cancer therapies.
Researchers at Duke University have discovered a way to restore bladder control in people with spinal cord injury using electrical stimulation of the pudendal nerve. This technology, known as a 'bladder pacemaker,' could significantly improve quality of life for over 200,000 Americans affected by SCI.
Lynne E. Maquat and her team identified a novel pathway for regulating RNA degradation, called Staufen1-mediated degradation (SMD). This mechanism affects numerous transcripts and is a new form of gene regulation. SMD activity may be regulated by cell signaling pathways.
Researchers found that human genes are less carefully controlled due to a small population size, leading to increased disease risk. The study suggests that natural selection would have overridden harmful mutations with a larger population.
A recent study published in Neurology found no significant association between increased physical activity and the risk of developing amyotrophic lateral sclerosis (ALS). However, it was discovered that higher leisure time physical activities before age 25 resulted in an earlier onset of the disease by seven years.
A review of nine studies found that pre-diabetics using weight-loss interventions can lose between 2-3 kilograms or four to six pounds in one to two years. The interventions also decreased blood sugar levels, blood pressure, and cholesterol levels slightly among pre-diabetics.
A study by Johns Hopkins Medicine found that pulsatile lavage equipment was the cause of an Acinetobacter baumannii outbreak, infecting 11 patients. The investigation led to changes in hospital procedures, including wearing masks and gloves during procedures and using private treatment rooms.
Chronic kidney disease affects over 7.4 million Americans with less than half the kidney function of a healthy adult, while an additional 11.3 million have at least half normal function but persistent protein in their urine. Raising awareness and controlling diabetes and hypertension are critical to reducing progression and complications.
Yale researchers, Jorge Galán, Ruslan Medzhitov, and John Carlson, have been awarded $3 million to investigate Campylobacter jejuni and its impact on the immune system. The funding will support their work in understanding infectious disease mechanisms and developing new treatments.
A recent survey found that asthma control in US children falls short of national treatment goals, with most experiencing frequent symptoms and missed school days. The study highlights the need for better communication between parents and children to effectively manage the condition.
Researchers found that implementing a series of simple interventions, including education and safety checklists, significantly reduced catheter-related infections in an ICU setting. The interventions prevented over 40 infections and saved nearly $2 million in additional healthcare costs.
A new study reveals that patients with asthma experiencing high variability in disease symptoms incur greater direct and indirect costs, including hospitalizations, emergency visits, and lost productivity. High variability patients also report more frequent unscheduled doctor visits and asthma interrupts daily activities more often.
Researchers are studying the genetic mutations that make mosquitoes resistant to pyrethroid pesticides, a key strategy for controlling diseases like St. Louis encephalitis and West Nile encephalitis in Texas urban areas. The study aims to develop new methods of mosquito control to prevent resistance.
Heavy lifetime alcohol users have a 60 percent greater risk of developing metabolic syndrome compared to those in the lowest category. The study found that drinking patterns independently predict the risk of metabolic syndrome.
A retrospective cohort study of 198 children who underwent fundoplication at Texas Children's Hospital from 1996-1999 found that fundoplication is not a long-term solution for treating GERD in children. Alternative medical treatments, such as histamine-2 receptor antagonists and proton pump inhibitors, are recommended instead.
Researchers aim to understand why some generations exhibit higher rates of violence in adolescents, using data from the Pittsburgh Youth Study. The study will examine age groups and potential cultural or economic factors influencing violence.
Scientists at UCLA and Univ. of Utah have discovered that the hormone hepcidin regulates ferroportin, an iron-transporting molecule, controlling iron release in the bloodstream. This finding may lead to treatments for hemochromatosis and anemia of chronic disease, affecting millions worldwide.
A study published in PLOS Medicine found that supervised treatment interruptions, which aim to boost natural immunity by briefly exposing patients to low levels of the virus, are ineffective in controlling HIV-1 viremia. Researchers were able to achieve transient control of the virus in some patients, but it was not sustained over time.
Studies examining prehypertension reveal a significant increase in heart disease and stroke risks among affected individuals. Prehypertension is associated with unfavorable levels of other major cardiovascular disease risk factors and contributes to a substantial burden on the healthcare system.
Early diagnosis of cystic fibrosis through newborn screening can lead to improved height and weight measurements, better pulmonary status, and cognitive benefits. Implementing CF newborn screening in all states aims to give people with this disease the best odds at living longer, healthier lives.
A pilot project by Voxiva and PATH aims to track and reduce Japanese encephalitis incidence through improved surveillance and response. The system uses phone and web-based technology to collect and analyze data, enabling health officials to respond quickly to reported cases and identify outbreaks.
Over 30 years of follow-up, Vietnam veterans experienced a 7% higher death rate from external causes, including motor vehicle collisions, suicides, and homicides. This excess mortality was limited to the first five years after discharge, but also included higher mortality rates from unintentional poisonings and drug-related deaths.
A randomized controlled trial found that patients referred to an alcohol-health worker after visiting the emergency department consumed significantly less alcohol over six months. This intervention reduced reattendance at emergency departments by 0.5 visits on average per year.
Researchers, led by Dr. Shelagh Campbell, study ATM mutants to understand the molecular mechanisms behind A-T disease. They found that mutant males exhibited locomotor defects, sensitivity to ionizing radiation, and chromosome instability similar to those seen in human patients.
The study suggests that monitoring glycated hemoglobin levels can help identify individuals at increased risk of developing cardiovascular disease. Researchers found a significant association between elevated glycated hemoglobin levels and increased risk of large-vessel cardiovascular disease among people with type II diabetes.
The March of Dimes survey found that 49 percent of women who have been on low-carb diets in the past six months take a daily multivitamin containing folic acid. This increase suggests that women are becoming more aware of the importance of folic acid for preventing birth defects.
The research project aims to identify tick genes that spread serious illnesses, such as Lyme disease. By analyzing the genome data, scientists hope to develop vaccines to block transmission of microbes that cause tick-borne illnesses.
Studies found strong evidence supporting treatment of systolic hypertension in older persons with SBP of at least 160 mm Hg. Treatment guidelines recommend thiazide diuretics and long-acting calcium channel blockers as first-line therapy for SH. Despite effectiveness, poor control of SH among patients is increasing.
A survey in 2000 showed a decrease in tuberculosis prevalence of around a third compared to the original survey in 1990. China aims to reach the UN Millennium Development Goal of halving TB prevalence between 2000 and 2015 with its expansion plans.
A study of 166,000 Americans found that those reporting more depressive symptoms were at increased risk for illnesses, with exercise and higher education reducing symptoms. Young adults aged 18-24 reported the highest number of days with depressive symptoms.
The Lancet editorial highlights concerns about the practicality of implementing government plans for cleaner hospitals and lower rates of infection. Key issues include a lack of resources and clear timetable for implementation, as well as insufficient sanctions for hospitals that fail to maintain acceptable levels of cleanliness.
A team of researchers has made a groundbreaking discovery that sheds light on the intricate process of morphogenesis, a crucial step in embryonic development. By studying convergent extension in frog embryos, they found that a single mechanism controls both cell differentiation and tissue elongation.
The UK national cervical screening programme has saved approximately 5,000 lives annually by reversing the rising trend in cervical cancer deaths among women under 35. The programme's success has also led to a significant reduction in costs, with a cost per life saved of less than £40,000.
The Global Fund's performance-based payment system is challenging for recipients and sub-recipients to meet, hindering disease control intervention scaling-up. Experts call for clearer guidelines, improved coordination among donors, and simpler funding systems to achieve the Fund's goals.
Researchers recreated mammalian cell self-organization patterns in a test tube using mathematical formulas dictating cell interactions. This may help improve tissue regeneration methods and understand mechanisms behind birth defects and heart disease.
Chronic diseases are the largest cause of death worldwide, with a projected increase in global prevalence over the next two decades. Key risk factors include tobacco use, unhealthful diets, and lack of physical activity, with most cases occurring in developing countries.
A new government survey reveals that 36 percent of US adults use some form of complementary and alternative medicine (CAM), with prayer being the most commonly used therapy. The survey found that CAM use was more prevalent among women, those with higher education, and people who had been hospitalized in the past year.
Research finds that people trust health professionals and are cautious about online health information, yet appreciate recommendations from healthcare providers. E-health resources enhance control and reassurance for parents and children managing chronic diseases.
Researchers have discovered biomarkers for ALS in cerebrospinal fluid, which could enable rapid diagnosis and prompt treatment. These biomarkers have high sensitivity and specificity, and may be used to monitor drug effectiveness in clinical trials.
Female ticks require six to 10 days to engorge fully, a process stimulated by an engorgement factor protein in male seminal fluid. Researchers have identified this protein and developed a vaccine candidate to protect cattle against tick-borne diseases.
The article discusses the ongoing threat of rabies in Africa and Asia, where dog rabies epidemics hinder control efforts. Mary Warrell highlights the importance of addressing this issue through improved surveillance and vaccination methods.
US state and territorial health departments have limited online resources for reporting infectious diseases, a study found. Updating these sites to provide complete, accessible disease reporting information could strengthen partnerships between clinicians and public health officials and improve disease surveillance.
A recent survey found that most Americans remain confident in the safety of their beef supply following a confirmed case of mad cow disease in Washington State. The study suggests that consumer confidence has been boosted by government actions and trust in food regulators, but some have expressed concerns about the risk of transmission.
A recent study found that only 37% of adults with diagnosed diabetes are achieving the American Diabetes Association's goal for blood glucose control, while nearly half have high cholesterol and high blood pressure. The lack of lifestyle changes, such as exercise and weight loss, is a major contributor to this issue.
A study examining trends in adults with diagnosed diabetes found that only a small percentage met recommended targets for HbA1c, blood pressure, and total cholesterol. The authors highlight the need for ongoing monitoring, empowering clinicians and patients to improve care quality and reduce vascular disease risk.
A total of 2,521 probable cases were reported in Beijing during the SARS outbreak. The city's swift response, including improved infection control practices and quarantine measures, likely contributed to the rapid decline in new cases.
A biochemical chain of events governs cell size in multiple diseases. Researchers discovered that AMPK regulates TSC2 activity, which limits mTOR activity, thereby controlling cell growth. This chain of events may be targeted by the drug Rapamycin to treat genetic syndromes.
The Schistosomiasis Control Initiative will support Burkina Faso, Mali, Niger, Zambia and Tanzania in treating 15 million people with praziquantel and albendazole over four years. The initiative aims to deliver treatment to 3 million children and reduce the parasite's impact on African communities.
Researchers at the University of Pittsburgh Medical Center have identified protein biomarkers that accurately diagnose ALS with near 100% specificity and sensitivity. The findings may lead to a new test for early-stage ALS, enabling faster diagnosis and monitoring of treatment efficacy.
Researchers found that isolated patients were twice as likely to experience adverse events during hospitalization and did not receive adequate supportive care. Isolation is a highly effective measure for infection control, but hospitals need to address its drawbacks, including delayed responses to patient calls.