Articles tagged with Disease Prevention
Researchers found a link between vitamin D deficiency and chronic diseases such as cognitive decline, depression, and osteoporosis in older adults. The study highlights the need for universal guidelines on testing and treating vitamin D deficiency to prevent age-related disorders.
A comprehensive analysis found that the NIH spends only 7-9% of its budget on behavioral interventions to prevent NCDs, despite 70% of US deaths being due to these diseases. Increasing funding for prevention research could save lives and reduce healthcare costs.
The latest issue of Global Heart explores the challenges of delivering critical care in resource-limited settings, where cardiovascular disease is emerging rapidly. Key findings include the need for effective diagnostic resources and treatments for conditions like sepsis, ARDS, and pulmonary vascular disease.
Scientists have identified a weak spot in the life cycle of malaria parasites, where female parasites store fat differently to males. This discovery could lead to new drugs targeting the fat molecule gABCG2, potentially preventing the spread of the disease.
Endemic infectious diseases continue to affect millions of individuals in the US, with racial and ethnic minorities disproportionately affected. Emerging vector-borne and zoonotic disease infections are threatening new areas and populations.
A study published in Blood demonstrated that the C1s antibody prevents the destruction of human red blood cells exposed to patient autoantibodies in cold agglutinin disease. The antibody inhibits Complement deposition on the red blood cell membrane, preventing macrophage engagement and lysis.
Research finds that protein TG2 enables bacteria Porphyromonas gingivalis to adhere to cells, and blocking its associations prevents bacterial adhesion. The study provides insight into a potential target for preventing gum disease.
A study by Bowling Green State University researchers suggests a correlation between excessive tanning and mental health symptoms such as OCD and BDD. The findings indicate that prevention messages may not be effective for those with these conditions, highlighting the need for further assessment and treatment.
Researchers found that even modest weight reduction (5%) can significantly improve OSA and metabolism in overweight patients, preventing disease progression over four years. The study provides first-time long-term evidence of the effectiveness of weight loss in managing OSA.
Researchers developed a mathematical model to evaluate the effectiveness of drug alternatives to antibiotics in limiting disease spread. These treatments can prevent infections from evolving too quickly, but also increase the risk of disease transmission.
Research suggests that breast cancer ads can be ineffective when they emphasize a woman's vulnerability, leading to motivated forgetting. This phenomenon occurs when people feel threatened about their gender or social identity, causing them to suppress memories of the ad and its message.
A study found that First Nations adults with diabetes are more than double the risk of developing end-stage kidney disease. The high rates of kidney disease among First Nations people are attributed to younger onset of diabetes, leading to increased survival time and likelihood of progression to end-stage renal disease.
Researchers discovered a disease mechanism in type 1 diabetes that can be targeted using simple, naturally occurring molecules like TUDCA. The study highlights the potential for improving ER function and reducing the incidence of T1D in high-risk populations.
Carl Nathan, MD, receives $20,000 prize for discoveries in immunology; monograph published in Molecular Medicine explores inspiration and purpose in scientific inquiry. The Anthony Cerami Award aims to document innovations and discoveries in medicine and healthcare.
Two neurology researchers propose that prion-like protein aggregates drive multiple brain diseases associated with aging. These seeds disrupt nervous system function and can stimulate the aggregation of other proteins, suggesting therapeutic strategies to combat these diseases.
Researchers at the Montreal Heart Institute have discovered a new compound that prevents valve deterioration and can even reverse aortic valve stenosis. The treatment could help avoid major complications of heart surgery and prevent heart failure and sudden death.
A study found that only a few low-and middle-income countries have implemented robust national policies to prevent noncommunicable diseases, such as reducing fat and salt intake. The majority of these countries lack adequate strategies to promote healthier diets and physical activity.
Research reveals that non-pathogenic bacteria naturally occurring in the human intestine can eliminate Stx from the intestinal contents and completely prevent HUS in a mouse model.
A small-scale clinical study investigated the effects of eating one Hass avocado a day on risk factors for cardiovascular disease compared to similar moderate fat diets. The research suggests that avocados may offer unique benefits beyond their monounsaturated fat content, contributing to greater cardiovascular health benefits.
A new report highlights regulating alcohol outlet density as an effective strategy to reduce excessive drinking and related harms. By limiting outlets per population or using land-use powers, localities can address excessive drinking and create healthier communities.
Researchers have developed nanomedicines that home specifically to damaged tissue to repair it, preventing tissue damage in inflammatory conditions. These tiny, targeted drug particles have the potential to treat chronic diseases without side effects.
Researchers have found a gene associated with an unusual type of cholesterol that increases the risk of developing aortic stenosis, the most common form of heart valve disease. High levels of Lipoprotein (a) cholesterol are predicted primarily by an individual's genetic make-up.
A study published in the Journal of Immunology suggests that blocking the activity of C5aR can effectively prevent and treat periodontitis. Researchers found that mice treated with a molecule blocking C5aR developed less inflammation and bone loss compared to those without treatment.
A six-year study found a correlation between vitamin D3 serum levels and subsequent incidence of Type 1 diabetes, suggesting a preventive role for vitamin D3 in this disease. Researchers estimate that achieving an optimal serum level of 25(OH)D at 50 ng/ml can lower the risk of developing type 1 diabetes by half.
Researchers at Rutgers University found a protein defect that leads to axtaxia-telangiectasia, a degenerative disease affecting cerebellum and brain function. Treating the defective protein with TSA restored motor coordination in mice, suggesting potential reversal of symptoms.
A study found exemestane significantly worsens age-related decreases in bone mineral density by three times, even with adequate calcium and vitamin D intake.
Researchers have identified retroviruses and herpesviruses in illegally imported wildlife products, highlighting the potential public health risk of the illegal wildlife trade. The study suggests that surveillance at ports can help prevent disease emergence.
Researchers identified two substances in licorice root that kill major bacteria responsible for tooth decay and gum disease. Licoricidin and licorisoflavan A were found to be effective antibacterial substances, potentially treating or preventing oral infections.
A lack of understanding about the healthcare system leads to suboptimal treatment adherence and preventable outcomes. Education, including high school courses and community programs, is key to empowering patients and promoting optimal health.
Healthy mouth bacteria provide ideal conditions for gum disease to develop, according to research from Queen Mary University of London. The study found that manipulating normal bacteria in the mouth can prevent periodontal disease, a condition affecting 54% of adults in the UK.
The NIH study found that etanercept reduces symptom frequency and severity in TNF receptor-associated periodic syndrome (TRAPS) patients. However, long-term treatment effects on preventing amyloidosis are uncertain.
Researchers at Douglas Mental Health University Institute are launching the world's first prevention study on Alzheimer's disease. They will recruit 250 healthy adults aged 60 or over with a family history of the condition and observe their biomarkers for ten years to find preventative agents.
Experts urge collective global effort to stem cardiovascular diseases, type 2 diabetes, and other major health challenges. A United Nations summit will draw on experiences from the HIV/AIDS pandemic, promoting research, prevention, and treatment efforts.
The new decade of vaccines brings hope for disease prevention through innovative technologies like glycoconjugate vaccines and reverse vaccinology. Despite challenges, vaccines have already led to significant reductions in morbidity and mortality due to diseases like smallpox, measles, and meningitis.
Researchers aim to efficiently identify more HIV-infected people through expanded voluntary testing programs. They also seek innovative approaches to curing HIV/AIDS by eradicating or suppressing the virus in infected individuals.
The ENERCA network has published a series of recommendations for disease management and prevention of complications in children with sickle cell disease. The guidelines recommend universal neonatal screening, prophylaxis with penicillin, and transcranial Doppler scanning to prevent infections and strokes.
Researchers studied malaria parasite reproduction, finding damaging male and female forms can prevent disease transmission without killing them entirely.
A new study suggests that periodontal disease may increase the risk for respiratory infections like COPD and pneumonia. Regular oral care can help prevent periodontal disease, which has been linked to other chronic inflammatory diseases.
A recent study from the University of Texas Medical Branch at Galveston found that aggressively marketed drugs tend to offer less benefit and more harm to most patients. The 'inverse benefit law' highlights the need for physicians to critically evaluate commercial marketing and prioritize patient safety.
Scientists in Japan have discovered a compound in tomatoes that enhances fatty acid oxidation and regulates hepatic lipid metabolism. The extract, 9-oxo-octadecadienoic acid, has anti-dyslipidemic effects and can help prevent vascular diseases.
The European Alliance of Associations for Rheumatology (EULAR) welcomes the EU Council's Conclusions on chronic diseases, which call for coordinated measures to address these conditions. EULAR highlights the importance of innovative approaches, patient-centred policies, and integrated healthcare systems to manage musculoskeletal diseases.
The US PLWHA death rate decreased from 1996-2006, with a sharp drop in AIDS-defining illnesses, while non-HIV related diseases like heart disease and liver disease increased, according to CDC analysis.
A growing burden of chronic disease threatens low-income and middle-income countries; weak national health systems hinder effective interventions. Strengthening health systems can improve responses to chronic diseases, benefiting other health services as well.
Patients with peripheral artery disease experience high rates of hospitalizations and associated costs, even after initial procedures to clear blockages in leg arteries. Preventive strategies, including healthy lifestyle adoption, may help arrest or stall the progression of the disease.
The Chronic Disease Alliance, a coalition of 10 European health organizations, has been recognized for its efforts to improve the prevention of chronic diseases at the European level. The alliance has produced a policy paper that identifies central causes of chronic diseases and furnishes action proposals on how to combat their spread.
Research suggests that periodontal disease may affect more American adults than previously estimated, with a potential 50% increase in prevalence. The study highlights the importance of maintaining good oral health and regular dental check-ups to prevent gum disease.
Researchers analyzed 33,900 hospital-based outpatient visits to compare resident and staff physician performance. Resident physicians outperformed staff on four measures, including ACE inhibitor use for congestive heart failure and routine blood pressure screenings.
Global cancer leaders call for non-communicable diseases (NCDs) to be included in the Millennium Development Goals to address the growing health issue. NCDs, responsible for 35 million deaths worldwide, face a lack of indicators and inadequate funding, with less than 2% of overseas development aid allocated to these diseases.
The new criteria redefine RA by classifying it based on the confirmed presence of synovitis in at least one joint, absence of alternative diagnoses, and a combined score from four domains. Early diagnosis and treatment can prevent destructive joint damage with the help of synthetic and biological disease-modifying antirheumatic drugs.
Researchers compared two treatments for preventing strokes due to carotid artery disease, but found no clear winner. While surgery may be beneficial for patients who have had a stroke or temporary stroke in the past 12 months, stenting offers similar benefits for asymptomatic patients.
Researchers at UH are studying 'wireless connections' in the brain to prevent diseases like epilepsy and schizophrenia. They found that liver X receptor β and thyroid hormone receptor α play key roles in brain development and regulation.
The Physical Activity Guidelines for Americans recommend daily physical activity to prevent chronic diseases, with specific guidelines for youth, adults, and older adults. The guidelines emphasize the importance of promoting physical activity in clinical and public health practice.
A new accelerated radiotherapy regimen has been shown to improve disease-free survival and locoregional control without increasing late radiation side-effects in patients with head and neck cancer. The six-fraction per week schedule reduces treatment time while maintaining effective tumour control.
Researchers at HZI have discovered a new adjuvant, c-di-IMP, that enhances immune responses and provides long-lasting protection. The molecule has been shown to stimulate important effector mechanisms in mice, making it a promising candidate for improving existing vaccines.
A Northwestern University professor explores making public policy with limited information, recommending the elimination of inferior options and application of decision criteria to avoid poor outcomes in issues like global warming and vaccination policies.
Researchers at the University of Alberta have identified a universal mechanism that ensures peroxisomes transfer into cells after division, potentially leading to prevention or treatment of deadly disorders. The discovery has implications for screening carriers and could help babies born with peroxisome disorders survive longer.
A new study found that increased walking and cycling in cities like London and Delhi can reduce carbon dioxide emissions and improve public health more effectively than using lower-emission motor vehicles. The study suggests prioritizing pedestrian and cyclist infrastructure to create safe urban environments for mass active travel.
The National Institute of Allergy and Infectious Diseases (NIAID) has renewed a five-year, $56 million contract to study asthma in children living in lower-income, inner-city environments. The Inner-City Asthma Consortium (ICAC) will evaluate promising new therapies to reduce asthma severity and prevent disease.
Researchers found left side grafting has lower risk to donors compared to right lobe grafts, and recipients can achieve comparable survival rates with smaller graft sizes. The study suggests using left side grafts more frequently in adult-to-adult liver transplantation to reduce donor risk.
Researchers found that chlorhexidine-soaked wipes did not reduce neonatal sepsis or vertical transmission of group B streptococcus. The study suggests that other interventions are needed to target child mortality and achieve the Millennium Development Goal of reducing childhood mortality.