Articles tagged with Disease Prevention
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers identified a genetic mutation in nonhuman primates that closely resembles Pelizaeus-Merzbacher disease, a rare and progressive disorder affecting the central nervous system. The discovery was made possible by a massive genomic database built at OHSU's Oregon National Primate Research Center.
Researchers created a polymer coating that releases Lasioglossin-III, an AMP with broad-spectrum antibacterial activity, targeting specific infectious bacteria and preventing airway complications. The coating demonstrated significant antibacterial activity and prevented bacterial adherence to the tube.
Researchers found that UVB radiation from the sun causes chemical changes to DNA, leading to disease-causing mutations. This discovery sheds light on the origins of melanoma and highlights the importance of prevention efforts.
A study found that half of individuals who initially refused to receive secondary genomic findings changed their minds after receiving more detailed information. The research suggests that healthcare providers should give patients multiple opportunities to make and revise their choice.
Researchers at Tohoku University have identified a new gene, CCDC152 (L-IST RNA), which inhibits selenoprotein P (SeP) levels, reducing insulin resistance and glucose metabolism issues associated with type 2 diabetes. EGCG supplements may help increase L-IST, offering potential treatment options for diabetic patients.
A recent study by a MU researcher found that tick-borne diseases are on the rise in the Midwest, particularly in humid climates. The study collected data on various tick species and their activity patterns, providing valuable insights for public health officials.
Research at University of Jyvaskyla reveals that quality and quantity of enrichments influence well-being of aquaculture fishes. The study found that stone enrichments improve survival rates, while a higher number of stones also has a positive effect.
A new study published in JAMA Pediatrics found that introducing high doses of gluten from four months of age may prevent coeliac disease in children. The Enquiring About Tolerance (EAT) Study showed no cases of coeliac disease among infants who introduced gluten early, but further studies are needed for confirmation.
The USC-Buck Nathan Shock Center will explore the biology of aging and its impact on disease, with a focus on cellular senescence, genomic translation, and geroscience technology. The center aims to translate basic research into effective preventions and therapies to extend healthspan.
The Lancet report highlights that many countries are falling behind on their commitments to reduce premature deaths from chronic diseases. Despite a decline in death rates from some diseases over the past decade, others such as diabetes and lung cancer are not showing sufficient progress. The report warns that if current trends continu...
A new study reveals a significant increase in premature deaths from alcoholic liver disease, particularly among younger women. The gap between men and women's mortality rates has narrowed over the past two decades, with women dying on average two to three years earlier than men.
Adding corticosteroids to standard intravenous immunoglobulin treatment for high-risk Kawasaki disease patients can boost initial response and prevent complications. The combination approach reduced the need for a second course of therapy by 35% and the risk of coronary artery abnormalities by 47%.
A recent study found that only half of pregnant women worldwide who need Rh disease treatment actually receive it. The study, published in PLOS One, estimates that complications of Rh disease may be linked to the deaths of at least 50,000 fetuses and 114,000 newborns annually globally.
Researchers at Queen Mary University of London discovered a naturally suppressive gene that prevents Alzheimer's Disease in brain cells, leading to the development of a rapid drug-screening system. The system demonstrates proof-of-principle for early preventative-drug testing and identifies a potential biomarker for risk assessment.
Researchers seek to improve symptom control and patient comfort in ICU patients transitioning to palliative care. Administration of opiates before ventilation withdrawal may help alleviate distress, according to a recent study published in the journal Chest.
A new study found that Medicaid expansion significantly reduced uninsured rates among low-income residents in the Diabetes Belt. The increase in insurance coverage helped address access to care issues, leading to improved health outcomes and quality of life for those affected by diabetes.
Researchers at the University of Missouri have made a groundbreaking discovery by identifying the genetic mutation responsible for Chédiak-Higashi syndrome in domestic cats. This finding has significant implications for treating inherited diseases and preventing their transmission to future generations.
Since the mid-2000s, bone marrow transplant mortality rates have declined significantly, falling by 34% between 2003-2007 and 2013-2017. This improvement is largely attributed to advancements in prevention and treatment of infections and diseases related to transplantation.
A study from the University of Georgia found that over 90% of opioid-related hospitalizations are among patients with two or more chronic diseases, highlighting the association between chronic disease and opioid misuse. Researchers argue that prioritizing chronic disease prevention could alleviate the opioid epidemic.
The Lancet Global Health study found that on average, countries implemented just over half of the 18 WHO-recommended policies to reduce chronic diseases. Implementation improved over time, but some countries lagged behind, including the USA. Democratic centre-left countries tended to implement more policies.
A new therapeutic target for the treatment of Alzheimer's disease has been discovered, with research identifying elevated levels of the protein SFRP1 in the brains and cerebrospinal fluid of patients. Inactivated SFRP1 function prevents disease progression in mouse models.
A recent study has deciphered the near-atomic structure of filaments called 'pili' that extend from the surface of bacteria causing traveler's diarrhea. This breakthrough may lead to the development of new treatments and vaccines for the disease.
A systematic review found that moderate milk and dairy consumption during pregnancy and childhood can reduce the risk of frailty, sarcopenia, and certain types of cancer. The study also suggested that low-fat dairy products may have a protective effect against cardiovascular disease and type 2 diabetes.
The PHOENIx MDR-TB study compares the safety and efficacy of delamanid and isoniazid in preventing active MDR-TB disease in at-risk contacts. The trial will enroll approximately 5,610 participants across 12 countries.
Researchers from IKBFU discover that pine nut shells contain a carbohydrate-mineral complex rich in fibres and vitamins. This processed product is non-toxic and increases physical endurance, making it recommended as a sports nutrition product.
Shoukhrat Mitalipov, a germline gene therapy pioneer, argues that existing regulations can be strengthened to allow safe treatment. His 17-year-old son Paul also co-authored the editorial, highlighting the importance of understanding gene editing for non-scientists.
The Humanwide program at Stanford Medicine combines cutting-edge tools and a collaborative team-based method to provide proactive, personalized care. The pilot program successfully identified previously overlooked health conditions and future health risks in patients, setting them on a path to avoid serious medical problems.
Researchers have developed a new therapeutic strategy that targets the MLCK1 enzyme to restore epithelial barrier function and prevent gastrointestinal disease. By preserving and restoring the gut's critical lining of cells, this approach may help break the cycle of inflammation driving chronic diseases.
David Julian McClements, a renowned expert in nanotechnology, has won the Nicolas Appert Award for his work on functional foods and omega-3 fatty acids. Hang Xiao, a Clydesdale Scholar, received the Babcock-Hart Award for his research on dietary components that prevent chronic diseases.
A UMass Amherst study reveals that citrus compounds can decrease inflammation in the colon by transforming into powerful anti-inflammatory agents through gut bacteria. The research aims to develop diet-based strategies to prevent and treat colon-related diseases.
Researchers at City University of Hong Kong create innovative method to transport micro-droplets using capillary force on slippery surface, enabling detection of E. coli and S. aureus bacteria in biomedical analysis. This technology has potential applications in fog collection, water harvesting, heat exchangers, and other fields.
Researchers isolated antibodies from human survivors of Andes hantavirus infection that protected hamsters against the deadly disease. The antibodies shielded animals even after administration, suggesting they could be used as a preventative treatment for hantavirus cardiopulmonary syndrome.
Data from Neuroscience 2018 presents genetic deletion of SARM1 protecting axons and reducing biomarkers of neurodegeneration. SARM1 inhibition provides critical insight into developing disease-modifying therapeutics for patients with axonal degeneration.
Researchers at WSU have developed an implantable, biofuel-powered sensor that runs on glucose from body fluids to monitor biological signals. The sensor has shown high sensitivity in processing physiological and biochemical signals, making it a promising tool for disease detection.
The NIAID Strategic Plan for Tuberculosis Research prioritizes expanding fundamental knowledge of TB by using modern tools to better understand the disease. The plan also focuses on developing rapidly accurate inexpensive point-of-care tests for different forms of TB, as well as identifying host and microbial biomarkers.
The incidence of tickborne infections in the US has risen significantly over the past decade. Lyme disease, caused by the spirochete Borrelia burgdorferi, accounts for most reported cases, with over 30,000 annual cases in the US but an estimated 10 times that number.
Researchers found weight loss over 40 years linked to significant bone deterioration, increasing fracture risk by almost three-fold. Weight-bearing exercise and balanced diet may help counteract negative effects on the skeleton.
The NIH summit recommends a precision medicine approach to Alzheimer's treatment and prevention, with a focus on developing interventions tailored to an individual's unique risk profile. The recommendations aim to build a collaborative research ecosystem capable of delivering urgently needed cures for people at all stages of the disease.
A new Quick Response (QR) code-based system allows patients with Addison's disease to receive urgent clinical management information, improving emergency care. Healthcare professionals expressed a preference for QR code-linked information, and the system has shown promise in preventing unnecessary deaths linked to adrenal crisis.
Amino acid transporters are essential for capturing nutrients from blood vessels, which can be blocked by specific inhibitors to treat diseases. Blocking these functions can also enhance inhibition or excitation in the brain, a strategy used to treat chronic pain and possibly schizophrenia.
Shifting physicians' roles from transactional tasks to personalized care would enhance patient outcomes. Physicians would diagnose and provide tailored care, synthesizing data and advocating for patients.
Researchers discovered that a common blood pressure medication, methyldopa, can prevent the onset of type 1 diabetes in up to 60% of those at risk by blocking a specific molecule. The study used a supercomputer and found that methyldopa not only blocks the DQ8 molecule but also doesn't harm other immune cells.
A daily insulin pill did not slow down or prevent type 1 diabetes development among individuals with a higher risk of developing the disease. The trial involved 560 participants who received either oral insulin or a placebo, and found that time to diagnosis was not significantly different between groups.
Researchers found that topical application of Resolvin E1 on gum tissues prevented and treated gum disease, while also reducing the likelihood of advanced arterial plaque rupture. The study suggests effective preventive and therapeutic treatments for heart disease and gum disease without unwanted side effects.
Researchers at the University of Warwick have discovered a link between inflammation and autophagy, a cellular process that breaks down harmful elements. This understanding could lead to more effective treatments for gut diseases like colon cancer, Crohn's, and ulcerative colitis.
Researchers at the University of Copenhagen have discovered a new cattle disease called Facial Dysplasia Syndrome, which causes facial deformations and breathing problems in young calves. The disease is linked to a genetic mutation found in semen from one breeding bull, and its identification could help prevent further cases.
A new report from The Lancet Commission highlights opportunities to improve health in Sub-Saharan Africa by seizing the workforce's growth and transforming health systems. The report emphasizes the need for prevention, public health, and primary care, as well as addressing emerging challenges like non-communicable diseases.
The new 9vHPV vaccine targets nine high-risk HPV types, significantly reducing the risk of cervical cancer, genital warts, and HPV-related vulvar and vaginal cancers. The study found that the vaccine is highly effective in preventing HPV infection and disease, with a 97.7% reduction in risk.
A new study suggests that metabolically healthy obese adults consuming a diet high in unsaturated fats may be able to decrease their total cholesterol by 10 points. However, replacing saturated fats with unsaturated fats does not aid in weight loss.
Researchers found that low leg fat mass is a crucial factor in lean individuals at increased risk of cardiometabolic diseases, similar to lipodystrophy phenotypes. The study suggests personalized prevention and treatment strategies for metabolically unhealthy lean people.
A new study by Washington University in St. Louis found that access to quality health care for persons with disabilities has decreased significantly between 2004 and 2014 in Afghanistan.
Researchers have discovered that a gene called Mt2 in Wolbachia-infected mosquitoes produces an enzyme that blocks the transmission of deadly diseases. The study suggests that this mechanism can be replicated without Wolbachia, potentially opening new avenues for disease control without releasing modified insects into the wild.
Podoconiosis is preventable by wearing shoes in areas with red clay minerals, yet many Ethiopian children have misconceptions about the disease and its prevention. Research found that children believed barefoot exposure to dew or pond water was a risk factor, despite knowing symptoms and benefits of proper footwear.
Researchers at RMIT University have successfully completed phase one human trials of ingestible capsules that measure gas levels in the gastrointestinal tract. The technology has demonstrated thousands of times more sensitivity to gut gases than alternative methods, offering a reliable diagnostic tool for colon cancer.
The Cornell University-led Northeast Regional Center for Excellence in Vector Borne Diseases aims to educate a cadre of vector biologists and public health practitioners through new courses and a master's program. The center will conduct applied research to prevent, control, monitor, track and respond to vector-borne disease outbreaks.
Researchers conclude that vitamin D supplementation does not improve musculoskeletal outcomes such as falls or fractures. For those at high risk of deficiency, sunlight exposure and diet should be prioritized, with low-dose supplements considered on an individual basis.
A new report by the International Osteoporosis Foundation identifies 10 major care gaps that are preventing early assessment and treatment of osteoporosis. The report highlights the need for better case finding, communication, and public awareness to tackle the global healthcare crisis arising from fragility fractures.
The US Preventive Services Task Force (USPSTF) recommends screening for latent tuberculosis infection in people at increased risk due to their birthplace or living history. Treatment of LTBI with CDC-recommended regimens provides a moderate health benefit in preventing disease progression.
Researchers developed a predictive tool to assess future SCD risk among the general population. Key findings include traditional risk factors like smoking, high blood pressure, diabetes, and specific SCD-related predictors and biomarkers.
Researchers identified otulipenia as a rare inflammatory disease affecting young children, characterized by fever, skin rashes, diarrhea, and joint pain. The condition is caused by the malfunction of OTULIN, a single gene on chromosome 5, leading to an overproduction of inflammatory cytokines.