Articles tagged with Disease Prevention
The National Institute on Aging has expanded its network of cutting-edge Alzheimer's disease and related dementias centers, with two new centers in North Carolina and Texas. The Duke/University of North Carolina ADRC will focus on understanding age-related changes across the lifespan and identifying disparities in dementia among differ...
A new study found that non-Hispanic Black and Mexican American adults are diagnosed with type 2 diabetes at an average age of 46-47 years old, four to seven years earlier than non-Hispanic white adults. Preventive measures such as nutrition counseling and physical-activity programs can prevent or delay the onset of diabetes.
Researchers used new approaches to track Lyme disease in Texas, finding an overlap between tick-bite locations and human cases. The study suggests that tick-bite location may serve as an indicator for human disease risk in nonendemic areas.
Yang Gao's lab has received a $1.9 million NIH grant to investigate the mechanisms of proteins that produce copies of genomic DNA, with potential implications for cancer treatment. The research aims to understand how DNA replication and repair processes can be targeted to develop new therapies.
Researchers investigated COVID-19 transmission dynamics among close contacts of index patients, finding timing of exposure impacts disease development. The study also found severity of the index case is associated with clinical presentation in close contacts who develop COVID-19.
A randomized trial found that a shorter course of rifapentine-isoniazid therapy resulted in significantly higher treatment completion rates compared to a longer daily course. The findings suggest that this regimens can be more effective for preventing tuberculosis disease in individuals with HIV, particularly in high-transmission areas.
Researchers from Tokyo University of Science developed a self-powered diaper sensor that monitors urine sugar levels, providing an alternative biomarker for blood sugar monitoring. The sensor uses a biofuel cell powered by glucose in the urine, detecting sugar levels within 1 second and simplifying caretaking tasks.
The study highlights the need for vaccination in Africa, where 890 million people lack on-site water and 700 million lack in-home soap/washing facilities. Researchers emphasize that physical distancing and mask-wearing can reduce transmission by at least 80%.
Researchers have identified several drug contenders that can block or reduce SARS-CoV2 infection in cells, including lactoferrin and MEK-inhibitors. These findings suggest potential efficacy against COVID-19 variants, with ongoing clinical trials to examine their ability to reduce viral loads and inflammation.
A study of 1800 Japanese citizens aged 65 found that low weight and insufficient exercise are significant risk factors for sarcopenia. Those with possible sarcopenia exhibited higher degrees of frailty despite normal Specific Health Checkup results, highlighting the need for a test to identify sarcopenia early on.
A new study shows that having someone available to listen can improve cognitive resilience and reduce the risk of cognitive decline. The study found that individuals with higher listener availability had better cognitive function despite similar physical aging or disease-related changes.
A new study from University of Utah researchers explores how socioeconomic inequalities, particularly in Utah's Salt Lake County, contributed to racial minority groups being unequally affected by the COVID-19 pandemic. The study found that residents of affluent areas had lower rates of infection compared to those in low-income zip codes.
Despite guidelines and legal requirements, women remain underrepresented in cardiovascular clinical trials, limiting treatment data on cardiovascular disease. Research shows that women respond differently to drugs than men, highlighting the need for sex-specific data in optimal care.
Researchers found that longer time in education during early adulthood and higher-level job leads to better cardiovascular health two decades later. The study suggests that material factors like job control and stress play a role in shaping health outcomes.
Researchers identified a genetic mutation in nonhuman primates that closely resembles Pelizaeus-Merzbacher disease, a rare and progressive disorder affecting the central nervous system. The discovery was made possible by a massive genomic database built at OHSU's Oregon National Primate Research Center.
Researchers created a polymer coating that releases Lasioglossin-III, an AMP with broad-spectrum antibacterial activity, targeting specific infectious bacteria and preventing airway complications. The coating demonstrated significant antibacterial activity and prevented bacterial adherence to the tube.
Researchers found that UVB radiation from the sun causes chemical changes to DNA, leading to disease-causing mutations. This discovery sheds light on the origins of melanoma and highlights the importance of prevention efforts.
A study found that half of individuals who initially refused to receive secondary genomic findings changed their minds after receiving more detailed information. The research suggests that healthcare providers should give patients multiple opportunities to make and revise their choice.
Researchers at Tohoku University have identified a new gene, CCDC152 (L-IST RNA), which inhibits selenoprotein P (SeP) levels, reducing insulin resistance and glucose metabolism issues associated with type 2 diabetes. EGCG supplements may help increase L-IST, offering potential treatment options for diabetic patients.
A recent study by a MU researcher found that tick-borne diseases are on the rise in the Midwest, particularly in humid climates. The study collected data on various tick species and their activity patterns, providing valuable insights for public health officials.
Research at University of Jyvaskyla reveals that quality and quantity of enrichments influence well-being of aquaculture fishes. The study found that stone enrichments improve survival rates, while a higher number of stones also has a positive effect.
A new study published in JAMA Pediatrics found that introducing high doses of gluten from four months of age may prevent coeliac disease in children. The Enquiring About Tolerance (EAT) Study showed no cases of coeliac disease among infants who introduced gluten early, but further studies are needed for confirmation.
The USC-Buck Nathan Shock Center will explore the biology of aging and its impact on disease, with a focus on cellular senescence, genomic translation, and geroscience technology. The center aims to translate basic research into effective preventions and therapies to extend healthspan.
The Lancet report highlights that many countries are falling behind on their commitments to reduce premature deaths from chronic diseases. Despite a decline in death rates from some diseases over the past decade, others such as diabetes and lung cancer are not showing sufficient progress. The report warns that if current trends continu...
A new study reveals a significant increase in premature deaths from alcoholic liver disease, particularly among younger women. The gap between men and women's mortality rates has narrowed over the past two decades, with women dying on average two to three years earlier than men.
Adding corticosteroids to standard intravenous immunoglobulin treatment for high-risk Kawasaki disease patients can boost initial response and prevent complications. The combination approach reduced the need for a second course of therapy by 35% and the risk of coronary artery abnormalities by 47%.
A recent study found that only half of pregnant women worldwide who need Rh disease treatment actually receive it. The study, published in PLOS One, estimates that complications of Rh disease may be linked to the deaths of at least 50,000 fetuses and 114,000 newborns annually globally.
Researchers at Queen Mary University of London discovered a naturally suppressive gene that prevents Alzheimer's Disease in brain cells, leading to the development of a rapid drug-screening system. The system demonstrates proof-of-principle for early preventative-drug testing and identifies a potential biomarker for risk assessment.
Researchers seek to improve symptom control and patient comfort in ICU patients transitioning to palliative care. Administration of opiates before ventilation withdrawal may help alleviate distress, according to a recent study published in the journal Chest.
A new study found that Medicaid expansion significantly reduced uninsured rates among low-income residents in the Diabetes Belt. The increase in insurance coverage helped address access to care issues, leading to improved health outcomes and quality of life for those affected by diabetes.
Researchers at the University of Missouri have made a groundbreaking discovery by identifying the genetic mutation responsible for Chédiak-Higashi syndrome in domestic cats. This finding has significant implications for treating inherited diseases and preventing their transmission to future generations.
Since the mid-2000s, bone marrow transplant mortality rates have declined significantly, falling by 34% between 2003-2007 and 2013-2017. This improvement is largely attributed to advancements in prevention and treatment of infections and diseases related to transplantation.
The Lancet Global Health study found that on average, countries implemented just over half of the 18 WHO-recommended policies to reduce chronic diseases. Implementation improved over time, but some countries lagged behind, including the USA. Democratic centre-left countries tended to implement more policies.
A study from the University of Georgia found that over 90% of opioid-related hospitalizations are among patients with two or more chronic diseases, highlighting the association between chronic disease and opioid misuse. Researchers argue that prioritizing chronic disease prevention could alleviate the opioid epidemic.
A new therapeutic target for the treatment of Alzheimer's disease has been discovered, with research identifying elevated levels of the protein SFRP1 in the brains and cerebrospinal fluid of patients. Inactivated SFRP1 function prevents disease progression in mouse models.
A recent study has deciphered the near-atomic structure of filaments called 'pili' that extend from the surface of bacteria causing traveler's diarrhea. This breakthrough may lead to the development of new treatments and vaccines for the disease.
A systematic review found that moderate milk and dairy consumption during pregnancy and childhood can reduce the risk of frailty, sarcopenia, and certain types of cancer. The study also suggested that low-fat dairy products may have a protective effect against cardiovascular disease and type 2 diabetes.
The PHOENIx MDR-TB study compares the safety and efficacy of delamanid and isoniazid in preventing active MDR-TB disease in at-risk contacts. The trial will enroll approximately 5,610 participants across 12 countries.
Researchers from IKBFU discover that pine nut shells contain a carbohydrate-mineral complex rich in fibres and vitamins. This processed product is non-toxic and increases physical endurance, making it recommended as a sports nutrition product.
Shoukhrat Mitalipov, a germline gene therapy pioneer, argues that existing regulations can be strengthened to allow safe treatment. His 17-year-old son Paul also co-authored the editorial, highlighting the importance of understanding gene editing for non-scientists.
The Humanwide program at Stanford Medicine combines cutting-edge tools and a collaborative team-based method to provide proactive, personalized care. The pilot program successfully identified previously overlooked health conditions and future health risks in patients, setting them on a path to avoid serious medical problems.
Researchers have developed a new therapeutic strategy that targets the MLCK1 enzyme to restore epithelial barrier function and prevent gastrointestinal disease. By preserving and restoring the gut's critical lining of cells, this approach may help break the cycle of inflammation driving chronic diseases.
David Julian McClements, a renowned expert in nanotechnology, has won the Nicolas Appert Award for his work on functional foods and omega-3 fatty acids. Hang Xiao, a Clydesdale Scholar, received the Babcock-Hart Award for his research on dietary components that prevent chronic diseases.
A UMass Amherst study reveals that citrus compounds can decrease inflammation in the colon by transforming into powerful anti-inflammatory agents through gut bacteria. The research aims to develop diet-based strategies to prevent and treat colon-related diseases.
Researchers at City University of Hong Kong create innovative method to transport micro-droplets using capillary force on slippery surface, enabling detection of E. coli and S. aureus bacteria in biomedical analysis. This technology has potential applications in fog collection, water harvesting, heat exchangers, and other fields.
Researchers isolated antibodies from human survivors of Andes hantavirus infection that protected hamsters against the deadly disease. The antibodies shielded animals even after administration, suggesting they could be used as a preventative treatment for hantavirus cardiopulmonary syndrome.
Data from Neuroscience 2018 presents genetic deletion of SARM1 protecting axons and reducing biomarkers of neurodegeneration. SARM1 inhibition provides critical insight into developing disease-modifying therapeutics for patients with axonal degeneration.
Researchers at WSU have developed an implantable, biofuel-powered sensor that runs on glucose from body fluids to monitor biological signals. The sensor has shown high sensitivity in processing physiological and biochemical signals, making it a promising tool for disease detection.
The NIAID Strategic Plan for Tuberculosis Research prioritizes expanding fundamental knowledge of TB by using modern tools to better understand the disease. The plan also focuses on developing rapidly accurate inexpensive point-of-care tests for different forms of TB, as well as identifying host and microbial biomarkers.
The incidence of tickborne infections in the US has risen significantly over the past decade. Lyme disease, caused by the spirochete Borrelia burgdorferi, accounts for most reported cases, with over 30,000 annual cases in the US but an estimated 10 times that number.
Researchers found weight loss over 40 years linked to significant bone deterioration, increasing fracture risk by almost three-fold. Weight-bearing exercise and balanced diet may help counteract negative effects on the skeleton.
The NIH summit recommends a precision medicine approach to Alzheimer's treatment and prevention, with a focus on developing interventions tailored to an individual's unique risk profile. The recommendations aim to build a collaborative research ecosystem capable of delivering urgently needed cures for people at all stages of the disease.
A new Quick Response (QR) code-based system allows patients with Addison's disease to receive urgent clinical management information, improving emergency care. Healthcare professionals expressed a preference for QR code-linked information, and the system has shown promise in preventing unnecessary deaths linked to adrenal crisis.
Amino acid transporters are essential for capturing nutrients from blood vessels, which can be blocked by specific inhibitors to treat diseases. Blocking these functions can also enhance inhibition or excitation in the brain, a strategy used to treat chronic pain and possibly schizophrenia.
Shifting physicians' roles from transactional tasks to personalized care would enhance patient outcomes. Physicians would diagnose and provide tailored care, synthesizing data and advocating for patients.
Researchers discovered that a common blood pressure medication, methyldopa, can prevent the onset of type 1 diabetes in up to 60% of those at risk by blocking a specific molecule. The study used a supercomputer and found that methyldopa not only blocks the DQ8 molecule but also doesn't harm other immune cells.
A daily insulin pill did not slow down or prevent type 1 diabetes development among individuals with a higher risk of developing the disease. The trial involved 560 participants who received either oral insulin or a placebo, and found that time to diagnosis was not significantly different between groups.
Researchers found that topical application of Resolvin E1 on gum tissues prevented and treated gum disease, while also reducing the likelihood of advanced arterial plaque rupture. The study suggests effective preventive and therapeutic treatments for heart disease and gum disease without unwanted side effects.
Researchers at the University of Warwick have discovered a link between inflammation and autophagy, a cellular process that breaks down harmful elements. This understanding could lead to more effective treatments for gut diseases like colon cancer, Crohn's, and ulcerative colitis.
Researchers at the University of Copenhagen have discovered a new cattle disease called Facial Dysplasia Syndrome, which causes facial deformations and breathing problems in young calves. The disease is linked to a genetic mutation found in semen from one breeding bull, and its identification could help prevent further cases.