Articles tagged with Disease Prevention
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new study links the composition of gut microbiome before infection to HIV susceptibility and progression. Men who contracted HIV in the early days of the pandemic had a greater relative abundance of pro-inflammatory vs. anti-inflammatory gut microbes, which contributed to their increased risk of developing AIDS.
Researchers at the University of Missouri have developed a free online resource that speeds up data analysis of human genomes three times faster than current methods. This enables scientists to see how an individual's genome makes them susceptible to different diseases in different ways, ultimately reducing associated costs and increas...
A large-scale study found that regular physical activity significantly reduces the risk of developing pneumonia and dying from it. The research, led by the University of Bristol, analyzed data from over 1 million participants and showed a strong association between exercise and reduced risk of pneumonia-related death.
A recent review reveals alarming increase in physician burnout among diagnostic radiologists, with causes including lack of control, social isolation and technological demands. Possible solutions include heightened engagement, dedicated reading room assistants and mindfulness techniques.
A new study by the Keck School of Medicine of USC finds that Medicaid expansion is associated with a significant reduction in mortality rates. The study, which tracked data from 2014-2018, found that expanding Medicaid coverage resulted in an estimated 3.8% decrease in adult deaths per year.
A new study from Karolinska Institutet and the University of Helsinki reveals how integrating digital tools, classical laboratory tests, and biomolecular measurements can enable individualized disease prevention. The researchers also found significant correlations between health risks and molecular factors associated with overweight, d...
Researchers at Karolinska Institutet found a strong link between the apoB/apoA-1 ratio and cardiovascular disease. Individuals with higher ratios had a greater risk of severe cardiovascular disease, including myocardial infarction and stroke.
Researchers discover a unique subset of group 3 innate lymphoid cells that circulate in the bloodstream and infiltrate the brain, sparking inflammation in conditions like MS. Countering their activity could be a new therapeutic strategy for such conditions.
Researchers found that high avocado consumption led to reduced caloric energy intake, lower dairy and meat consumption, and improved fiber and nutrient intake. However, unexpected decreases in calcium and certain minerals were also observed.
Researchers from the University of Manchester have discovered a new way to manipulate key assembly line enzymes in bacteria using CRISPR-cas9 gene editing. This approach could lead to the production of improved antibiotics with potentially improved properties, addressing the growing threat of antimicrobial resistance.
Research found that bats can adapt to diverse climates by finding similar roosting conditions, but those with high water loss are more heavily impacted by white-nose syndrome. This study highlights the importance of understanding bat hibernation patterns for conservation efforts.
A recent study estimates that COVID-19 vaccination prevented almost 470,000 deaths among people aged 60 years and older across Europe. The authors found that early implementation of vaccination was associated with the largest reduction in expected deaths.
A long-term study has revealed that drinking higher amounts of coffee may make you less likely to develop Alzheimer’s disease. The study found an association between coffee and several important markers related to Alzheimer’s disease, including executive function and amyloid protein accumulation in the brain.
Mass treatment with Ivermectin has halted the spread of river blindness in two Nigerian states, Plateau and Nasarawa, marking a major milestone in disease elimination efforts. Separate studies also show the potential for Ivermectin to reduce West Nile Virus transmission by mixing it into bird feed.
Researchers developed EDS-HAT, an AI-powered system combining machine learning and whole genome sequencing to detect clusters of similar infections in real-time. The system identified 99 clusters of infections and prevented potential transmissions in 65.7% of cases, saving the hospital $692,500.
A new study tracked the spread of a genetic mutation that causes young-onset heart arrhythmia across continents over centuries. The research found that the mutation was passed down from Northern Europe to other parts of the world through migration, and identified a specific gene, KCNQ1, as the cause of the disease.
Low-risk gamblers in Massachusetts reported the majority of gambling harms, confirming the 'prevention paradox' phenomenon. The study suggests targeting public health efforts towards primary prevention to reduce community harm.
Researchers will identify and track SARS-CoV-2 variants using genomic sequence analyses. The project aims to understand the emergence and spread of the virus in West Virginia, helping public health officials prepare for future outbreaks.
Researchers are tracking the health of over 1,500 women who had COVID-19 during pregnancy and their children to study the long-term effects of the virus. They aim to understand why some people develop post-acute sequelae of SARS-CoV-2 (PASC), also known as 'long COVID,' and others don't.
A new analysis found US states with water shutoff moratoria had significantly lower daily COVID-19 infection and death rates. Comprehensive moratoriums resulted in even greater reductions, suggesting universal access to water can help prevent public health crises.
A 51-country survey reveals that people who feel invincible to COVID-19 are less likely to get vaccinated and believe in the importance of individual actions. The study suggests that messaging emphasizing collective action is crucial in individualistic cultures.
A new vaccine has shown significant protection against Valley fever in dogs, offering hope for a potential human vaccine. The study found that two doses provided high levels of protection against the fungal disease.
Researchers have opened a novel study for a vaccine aimed at preventing triple-negative breast cancer, the most aggressive and lethal form of the disease. The phase I trial will determine the maximum tolerated dose of the vaccine in patients with early-stage triple-negative breast cancer.
A study found that only a third of public health policies had been fully implemented globally by 2020, with low-income countries and those with high corporate influence showing slow progress. The researchers suggest that corporate influence cancelled out the positive relationship between democracy and implementation, highlighting the n...
The COVID-19 pandemic has led to reduced influenza reporting, but vaccination and strengthened surveillance are critical for a possible resurgence. Research highlights the importance of flu vaccination and early testing for non-influenza respiratory viruses.
Researchers found that regular cycles of a fasting-mimicking diet in mice helped counteract the negative effects of a high-fat, high-calorie diet. The study suggests that this diet may have potential as 'medicine' to prevent obesity and heart disease.
Infection with measles virus triggers the activation of both RNA and DNA virus immune responses. The virus affects mitochondrial growth and division, causing their fusion and release of mitochondrial DNA into the cytoplasm. This leads to the activation of the cGAS immune response, which is also triggered by DNA viruses.
A new study found that women whose menstrual cycle length increased two years before menopause had better vascular health than those with stable cycles. Changes in cycle length may predict cardiovascular disease risk, allowing clinicians to recommend preventive strategies.
Researchers found that combining zinc oxide with small-molecule UV filter ingredients reduced UVA protection by 84.3-91.8% compared to non-mineral sunscreens. The study also showed toxic effects on zebra fish embryos when exposed to sunscreen mixtures containing zinc oxide.
A Tanzanian study found that laser treatment (SLT) successfully reduced eye pressure to normal levels in 61% of patients after one year, compared to 31% with daily eye drops. SLT may be an affordable alternative for glaucoma care in Africa.
Researchers found an early indicator of Alzheimer's disease is an oxidation-antioxidant imbalance in the blood. Oxidative markers increase up to five years before the onset of the disease, suggesting a potential avenue for prevention through antioxidant intake.
A new study reveals that childhood adversity is a major contributor to early and preventable causes of mortality and long-term physical and mental health issues. Childhood adversity was found to be associated with elevated risk for chronic diseases, including heart disease and cancer.
A Kaiser Permanente study found that the 2021 USPSTF guidelines will likely increase lung cancer screening of women, racial and ethnic minority groups, and individuals with lower socioeconomic status. This is expected to lead to an estimated 30% increase in lung cancer diagnoses compared to the 2013 recommendations.
Researchers found that nanosilver treatment can increase the risk of recurrent infections when used long-term due to pathogen adaptation. Long-term exposure allows bacteria like Pseudomonas aeruginosa to evolve and resume normal growth upon discontinuation of treatment.
A study published by the American College of Cardiology found a significant inverse relationship between oral health and COVID-19 severity, as well as delayed recovery and increased inflammation in patients with cardiovascular diseases. Researchers recommend maintaining good oral hygiene to prevent or decrease COVID-19 disease severity.
A new study suggests that natural infection can produce highly potent and broadly neutralizing memory B cells, which may provide longer-term protection against severe disease. In contrast, vaccines primarily stimulate circulating antibodies that fade over time.
The ACHIEVE GREATER Center aims to reduce cardiometabolic health disparities by implementing a proactive approach using community health workers and pharmacists. The center will use collaborative care, PAL2, to address multiple domains of influence contributing to disparate health outcomes in the Black population.
Researchers will investigate hidden signs of brain damage in REM behavior disorder, aiming to identify biomarkers that predict impending neurological disease. The goal is to delay the onset or prevent dementia or Parkinsonism through clinical trials.
The ACC Middle East 2021 conference will showcase the latest evidence-based strategies for improving heart health in the Middle East. The event features presentations from renowned experts on the most impactful clinical trials and contemporary best practices in treating cardiovascular disease.
The European Association for the Study of the Liver (EASL) is hosting its 57th International Liver Congress (ILC) 2022 in London, where experts will present and share the latest science on liver diseases. The event aims to enhance awareness, prevention, treatment, and management of liver diseases globally.
Researchers have found a protein called CD47 on the surface of infected cells that may protect them from immune system recognition, resulting in more severe disease. High CD47 levels are associated with higher risk factors for severe COVID-19, including age and diabetes.
Researchers discovered a nanomaterial that boosts antibody production while minimizing inflammation, opening up new possibilities for vaccine development. The 'micelle' scaffolds can be used to generate laboratory-scale quantities of therapeutic antibodies against real-world pathogens.
The COVID-19 pandemic has exposed a long-term underinvestment in the US public health workforce, with staff losses and underfunding for public health education. Experts recommend increasing access to education for future public health professionals and investing in the existing workforce to address this critical shortage.
Researchers at UC San Diego develop precision-guided sterile insect technique (pgSIT) to control mosquito populations. The system uses CRISPR to alter genes linked to male fertility and female flight in Aedes aegypti, reducing disease transmission.
A Finnish study discovered a positive association between standing and improved insulin sensitivity in adults with increased risk of type 2 diabetes and cardiovascular diseases. The researchers found that increasing daily standing time can help prevent chronic diseases, even if physical activity recommendations are not met.
The National Institute on Aging has expanded its network of cutting-edge Alzheimer's disease and related dementias centers, with two new centers in North Carolina and Texas. The Duke/University of North Carolina ADRC will focus on understanding age-related changes across the lifespan and identifying disparities in dementia among differ...
A study led by Ruixue Zhaoyang found that frequent and pleasant social interactions can boost cognitive performance in older adults. Participants who reported more social interactions had better cognitive performance on the same day and for days following.
A new study found that non-Hispanic Black and Mexican American adults are diagnosed with type 2 diabetes at an average age of 46-47 years old, four to seven years earlier than non-Hispanic white adults. Preventive measures such as nutrition counseling and physical-activity programs can prevent or delay the onset of diabetes.
Researchers used new approaches to track Lyme disease in Texas, finding an overlap between tick-bite locations and human cases. The study suggests that tick-bite location may serve as an indicator for human disease risk in nonendemic areas.
Yang Gao's lab has received a $1.9 million NIH grant to investigate the mechanisms of proteins that produce copies of genomic DNA, with potential implications for cancer treatment. The research aims to understand how DNA replication and repair processes can be targeted to develop new therapies.
Researchers investigated COVID-19 transmission dynamics among close contacts of index patients, finding timing of exposure impacts disease development. The study also found severity of the index case is associated with clinical presentation in close contacts who develop COVID-19.
A randomized trial found that a shorter course of rifapentine-isoniazid therapy resulted in significantly higher treatment completion rates compared to a longer daily course. The findings suggest that this regimens can be more effective for preventing tuberculosis disease in individuals with HIV, particularly in high-transmission areas.
Researchers from Tokyo University of Science developed a self-powered diaper sensor that monitors urine sugar levels, providing an alternative biomarker for blood sugar monitoring. The sensor uses a biofuel cell powered by glucose in the urine, detecting sugar levels within 1 second and simplifying caretaking tasks.
The study highlights the need for vaccination in Africa, where 890 million people lack on-site water and 700 million lack in-home soap/washing facilities. Researchers emphasize that physical distancing and mask-wearing can reduce transmission by at least 80%.
Researchers have identified several drug contenders that can block or reduce SARS-CoV2 infection in cells, including lactoferrin and MEK-inhibitors. These findings suggest potential efficacy against COVID-19 variants, with ongoing clinical trials to examine their ability to reduce viral loads and inflammation.
A study of 1800 Japanese citizens aged 65 found that low weight and insufficient exercise are significant risk factors for sarcopenia. Those with possible sarcopenia exhibited higher degrees of frailty despite normal Specific Health Checkup results, highlighting the need for a test to identify sarcopenia early on.
A new study shows that having someone available to listen can improve cognitive resilience and reduce the risk of cognitive decline. The study found that individuals with higher listener availability had better cognitive function despite similar physical aging or disease-related changes.
A new study from University of Utah researchers explores how socioeconomic inequalities, particularly in Utah's Salt Lake County, contributed to racial minority groups being unequally affected by the COVID-19 pandemic. The study found that residents of affluent areas had lower rates of infection compared to those in low-income zip codes.
Despite guidelines and legal requirements, women remain underrepresented in cardiovascular clinical trials, limiting treatment data on cardiovascular disease. Research shows that women respond differently to drugs than men, highlighting the need for sex-specific data in optimal care.
Researchers found that longer time in education during early adulthood and higher-level job leads to better cardiovascular health two decades later. The study suggests that material factors like job control and stress play a role in shaping health outcomes.