Researchers at Sanford Burnham Prebys Medical Discovery Institute found that enhancing protein-folding processes can help prevent harm to insulin-producing cells. The study revealed the importance of a chaperone protein called binding immunoglobulin protein and its cochaperone protein p58 IPK in maintaining proper proinsulin folding.
SourceSanford Burnham Prebys·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJun 11, 2026
A study by researchers at Institute of Science Tokyo has identified a key gene, DOCK10, involved in abnormal insulin secretion in insulinomas. The findings pave the way for novel diagnostic biomarkers and treatment options.
SourceInstitute of Science Tokyo·JournalCellular and Molecular Gastroenterology and Hepatology·TypeExperimental study·DateMar 26, 2026
A new study from the University of Victoria found that higher insulin levels at age 47 predicted younger onsets of hot flashes and night sweats. Insulin may be a stronger predictor of hot flashes when taking other metabolic variables into account, while body mass index (BMI) appeared more closely associated with estrogen level changes.
SourceUniversity of Victoria·JournalThe Journal of Clinical Endocrinology & Metabolism·TypeObservational study·DateJan 26, 2026
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A controlled feeding study out of South Dakota State University shows that older adults who reduced ultra-processed foods naturally consumed fewer calories, lost weight and abdominal fat, and showed improvements in insulin sensitivity and inflammation. This study provides evidence that the Dietary Guidelines for Americans can deliver s...
SourceSouth Dakota State University·JournalClinical Nutrition·TypeRandomized controlled/clinical trial·DateNov 24, 2025
A study published in Science Advances found that the ketogenic diet can have potentially dangerous impacts on metabolic health, including impaired blood sugar regulation and fatty liver disease. Mice fed the diet developed severe metabolic complications, with some changes starting within days.
SourceUniversity of Utah Health·JournalScience Advances·TypeExperimental study·DateOct 21, 2025
Researchers found that a combination of nicotinamide, a-lipoic acid, thiamine, pyridoxamine and piperine reduced AGEs, sticky plaque-like molecules, to curb hunger, lower insulin resistance and extend lifespan in mice. The compounds also reversed some molecular hallmarks of hypothalamic aging.
SourceBuck Institute for Research on Aging·JournalCell Reports·TypeExperimental study·DateOct 14, 2025
A new study from the Indian Institute of Science (IISc) reveals that glucose uptake is poorly managed in β-cells from people with Type 2 diabetes, leading to reduced insulin secretion. Restoring proper GLUT trafficking could slow disease progression and personalize therapies, according to the researchers.
SourceIndian Institute of Science (IISc)·JournalProceedings of the National Academy of Sciences·DateAug 18, 2025
Researchers at Karolinska Institutet found that a Western diet can cause long-lasting damage to the blood vessels of pancreatic islets, leading to impaired glucose metabolism. The study's findings highlight the importance of preserving islet vascular health in metabolic diseases.
SourceKarolinska Institutet·JournalJournal of Clinical Investigation·DateJun 9, 2025
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Researchers identified biomarkers like uric acid and bile acids as critical regulators of arterial stiffness and inflammation in adolescents with obesity. These findings provide new avenues for early intervention to prevent the progression of vascular stiffness and cardiovascular disease.
SourceBGI Genomics·JournalFrontiers in Medicine·DateJun 5, 2025
Researchers at Kyoto University have developed a new non-invasive diagnostic method for insulinomas, which achieved 100% diagnostic accuracy in a Phase II clinical trial. The new method using positron emission tomography (PET) probe successfully detected cases difficult to diagnose through existing methods.
SourceKyoto University·JournalThe Journal of Clinical Endocrinology & Metabolism·TypeRandomized controlled/clinical trial·DateMay 20, 2025
Research suggests flavonoids improve insulin sensitivity, enhance β-cell function, modulate the gut microbiota, inhibit gluconeogenesis, and regulate enteroendocrine hormones in type 2 diabetes management. Flavonoid-specific effects on GLP-1, GIP, PYY, and CCK secretion contribute to improved glycemic control.
SourceXia & He Publishing Inc.·JournalExploratory Research and Hypothesis in Medicine·DateMar 20, 2025
A team of scientists has successfully developed a novel platform for diabetes treatment utilizing bioink derived from pancreatic tissue and 3D bioprinting technology. The HICA-V platform replicates the structure and function of the human endocrine pancreas, supporting islet maturation and functional enhancement.
SourcePohang University of Science & Technology (POSTECH)·JournalNature Communications·DateMar 19, 2025
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A study by University of Gothenburg researchers found that consuming sulforaphane from broccoli sprouts improved blood sugar levels in people with prediabetes. The compound had a significant effect on fasting blood sugar levels, particularly in those with certain pathophysiological and microbiome characteristics.
SourceUniversity of Gothenburg·JournalNature Microbiology·TypeRandomized controlled/clinical trial·DateFeb 13, 2025
Scientists at the University of Würzburg have discovered that fruit fly nerve cells release insulin into the haemolymph when ingesting sugar, not when it's injected directly. This phenomenon is similar to the incretin effect in humans, suggesting complex mechanisms controlling insulin secretion.
SourceUniversity of Würzburg·JournaleLife·TypeExperimental study·DateFeb 5, 2025
A new study identifies molecular mechanisms of the progression from gestational diabetes to type 2 diabetes, finding reduced levels of sphingolipids in blood and a mutation in gene CERS2 linked to risk. The discovery could lead to new therapies and interventions to reduce the risk of this progression.
SourceUniversity of Pittsburgh·JournalScience Advances·TypeExperimental study·DateJan 14, 2025
The BBVA Foundation has awarded four researchers for their fundamental discoveries about the GLP-1 hormone, which has driven the development of new generation drugs for treating type 2 diabetes and obesity. The research also shows exciting therapeutic potential in neurological conditions such as Parkinson's and Alzheimer's disease.
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A Brazilian researcher at Harvard identified serotonin as the central role in postprandial hypoglycemia, a common complication of bariatric surgery. The study found that serotonin levels increase significantly after meals in affected individuals, unlike those without symptoms.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalJournal of Clinical Investigation·DateDec 10, 2024
A new study from Queen Mary University of London has identified the genetic drivers of early onset type 2 diabetes in South Asians, revealing a strong link to lower insulin production and unfavorable body fat distribution. The research also sheds light on treatment responses, highlighting the need for precision medicine approaches.
SourceQueen Mary University of London·JournalNature Medicine·TypeObservational study·DateNov 26, 2024
A recent study published in Nutrition & Diabetes found that consuming over 45% of daily calorie intake after 5 p.m. is associated with increased glucose levels, regardless of individual weight or body fat composition. This can lead to a higher risk of type 2 diabetes, cardiovascular disease, and chronic inflammation.
SourceUniversitat Oberta de Catalunya (UOC)·JournalNutrition and Diabetes·TypeExperimental study·DateNov 19, 2024
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Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
The EAT2 study, led by Dr. Ursula White, investigates the lasting health effects of short-term weight gain and loss on fat tissue and overall health. Participants will undergo a dietary intervention program followed by an eight-week weight loss treatment.
SourcePennington Biomedical Research Center·DateOct 18, 2024
Researchers at Brown University have found a way to extend the lifespan of flies by suppressing a hormone that regulates insulin secretion. The study suggests that certain medications used to treat human obesity and diabetes may also impact aging, making it a promising area of research for future studies.
SourceBrown University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateOct 16, 2024
Scientists discovered the highest natural blood sugar levels in mammals, found in a species of bats that can survive on a diet rich in sugars. The study's findings suggest that these bats have evolved unique strategies for glucose regulation, which may hold potential for managing metabolic diseases in humans.
SourceStowers Institute for Medical Research·JournalNature Ecology & Evolution·TypeExperimental study·DateAug 28, 2024
Scientists have generated a comprehensive map of gene targets regulated by HNF4A and HNF1A in human pancreatic beta cells and liver cells. The study identified novel gene targets in pancreatic beta cells that may play roles in regulating insulin secretion, providing valuable insights into potential therapeutic targets for diabetes.
SourceAgency for Science, Technology and Research (A*STAR), Singapore·JournalNature Communications·DateJun 25, 2024
A Flinders University study found that exposure to brighter light at night is associated with a higher risk of developing type 2 diabetes. The research used data from approximately 85,000 people and tracked their light levels for nine years.
SourceFlinders University·JournalThe Lancet·TypeExperimental study·DateJun 24, 2024
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A potential new strategy for reducing diabetes risk associated with antipsychotic medications involves co-administering drugs that block dopamine receptors in the brain alongside those that stop these same receptors in the pancreas. This approach may limit metabolic side effects and improve glucose metabolism.
SourceUniversity of Pittsburgh·JournalDiabetes·DateJun 13, 2024
Researchers developed an antioxidant gel to preserve islet function after pancreas removal, significantly improving survival and preserving normal blood sugar levels in animals. The new approach could enable patients to live pain-free without complications of diabetes.
SourceNorthwestern University·JournalScience Advances·TypeExperimental study·DateJun 7, 2024
A comparative study of four major type 2 diabetes medications reveals differences in medication acceptance, quality of life, insulin secretion, and mortality. The GRADE Study found that younger age and higher blood sugar levels at baseline were associated with poor blood sugar control over time.
SourcePennington Biomedical Research Center·JournalDiabetes Care·DateMar 25, 2024
A HKUST research team identified TMED10 as a protein that facilitates the secretion of insulin-like growth factor 2 (IGF2), which is crucial for muscle stem cell differentiation. The study provides valuable insights into the mechanisms underlying IGF2's functions and suggests potential therapeutic strategies to modulate its signaling.
SourceHong Kong University of Science and Technology·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateDec 6, 2023
Researchers from Cornell and University of Alberta have developed an under-the-skin implant that can secrete insulin without immunosuppression. The approach offers an easier alternative to traditional transplants or insulin injections, with the potential for long-term management of Type I diabetes.
SourceCornell University·JournalNature Biomedical Engineering·DateDec 5, 2023
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Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
A drug currently in clinical trials as a cancer therapy can also stimulate pancreatic beta cells to secrete insulin, revealing a new mechanism for insulin regulation in type 2 diabetes. The preclinical discovery provides a new chemical tool for probing the biology of diabetes and could lead to better treatments.
SourceWeill Cornell Medicine·JournalNature Chemical Biology·DateNov 9, 2023
A preclinical study by Weill Cornell Medicine researchers reveals that activating a pathway to promote cell division can expand insulin-producing cells without impairing their function. The study's findings support the concept that beta cell mass can be expanded without compromising function.
SourceWeill Cornell Medicine·JournalJournal of Clinical Investigation·DateNov 8, 2023
Research finds that hyperglycemia-induced hypoxia disrupts pancreatic beta-cell function, leading to impaired insulin secretion. Overexpression of BHLHE40 impairs insulin secretion by reducing MAFA expression.
SourceKumamoto University·JournalEMBO Reports·TypeExperimental study·DateSep 20, 2023
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Researchers have designed an implantable device that carries hundreds of thousands of insulin-producing islet cells and has its own on-board oxygen factory, generating oxygen by splitting water vapor. The device was tested in diabetic mice and maintained normal blood glucose levels for at least a month.
SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateSep 18, 2023
A new study from the University of Copenhagen reveals that GDF15 improves insulin sensitivity in rodents, particularly in their liver and fatty tissue. This finding raises interesting perspectives for treating type 2 diabetes and high blood pressure, as increased insulin sensitivity is a critical indicator of health.
SourceUniversity of Copenhagen - Faculty of Science·JournalCell Metabolism·DateAug 28, 2023
The study reveals that obesity-induced oxidative stress degrades CtBP2 protein, impairing pancreatic beta-cell function. This finding highlights the importance of targeting CtBP2 as a potential therapeutic strategy for obesity-related diseases.
SourceUniversity of Tsukuba·JournalCell Reports·DateAug 27, 2023
A recent study by Pennington Biomedical Research Center identifies GDF15 as a protein that acts as a cellular signal to enhance insulin secretion. High-intensity exercise training in patients with type 2 diabetes was found to have elevated levels of GDF15, associated with improved glycemic control.
SourcePennington Biomedical Research Center·JournalDiabetes·DateAug 22, 2023
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
A study published in Nature Communications reveals the controlled release of mucins and insulin by cells, with tetraspanin-8 acting as a gatekeeper. The regulated secretion is biphasic, involving rapid and slower releases of granules, which can be targeted to reset deregulated mucin and insulin secretion.
SourceCenter for Genomic Regulation·JournalNature Communications·TypeExperimental study·DateJul 3, 2023
Researchers have identified a number of candidate genes that may drive the development of conditions like Type 2 Diabetes. The study found that proteins such as PCSK1, SUR1 and GLUT2 play a role in calcium ion dynamics and insulin secretion.
Researchers at Weill Cornell Medicine have successfully converted human stomach stem cells into insulin-secreting cells, offering a promising approach to treating type 1 and severe type 2 diabetes. The transplants reversed disease signs in mouse models, suggesting good durability.
SourceWeill Cornell Medicine·JournalNature Cell Biology·DateMay 25, 2023
A recent study published in PLOS ONE found that patients with Type 2 diabetes who have full chewing function have significantly lower blood glucose levels compared to those with impaired chewing ability. The research highlights the importance of dental care and occlusal function in managing blood sugar levels.
SourceUniversity at Buffalo·JournalPLOS ONE·DateMay 8, 2023
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Researchers at Lund University have identified five subgroups of type 2 diabetes in India, characterized by genetic differences and varying levels of severity. The study suggests that early life undernutrition may contribute to the development of type 2 diabetes in India, while vitamin B12 deficiency is also a significant factor.
SourceLund University·JournalThe Lancet Regional Health - Southeast Asia·DateMay 2, 2023
A clinical study by Indiana University School of Medicine researchers found that oral verapamil can improve pancreatic beta cell function in children with new-onset type 1 diabetes, with a 30% increase in insulin secretion over the first year. The trial involved 88 participants and was published in JAMA.
SourceIndiana University School of Medicine·JournalJAMA·DateMar 1, 2023
A University of Minnesota-led study shows that verapamil can increase pancreatic insulin secretion by 30% in children with newly-diagnosed type 1 diabetes. The treatment was well-tolerated and had a favorable safety profile, making it an appealing option for children and adults with the condition.
SourceUniversity of Minnesota Medical School·JournalJAMA·TypeRandomized controlled/clinical trial·DateFeb 24, 2023
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
A recent study published in the Journal of Clinical Investigation found that PAX5 is strongly associated with impaired insulin secretion in type 2 diabetes. The research team identified 94 previously known genes and discovered many new genes differently expressed in individuals with type 2 diabetes.
SourceLund University·JournalJournal of Clinical Investigation·DateFeb 20, 2023
Researchers discovered microexons, short DNA sequences that play a vital role in insulin secretion and glucose homeostasis. The study found that genetic variants affecting microexon inclusion are linked to type-2 diabetes risk and fasting blood sugar levels.
SourceCenter for Genomic Regulation·JournalNature Metabolism·TypeExperimental study·DateFeb 9, 2023
A new study published in the Proceedings of the National Academy of Sciences has identified 14 pancreatic islet miRNAs associated with human type 2 diabetes. The study used a large sample size of nearly 65 human pancreatic islets to uncover these miRNAs, revealing potential mechanisms for disease development and novel therapeutic targets.
SourceCornell University·JournalProceedings of the National Academy of Sciences·DateFeb 9, 2023
A systematic review found that higher vitamin D intake was associated with a 15% decreased likelihood of developing type 2 diabetes in adults with prediabetes. Inexpensive vitamin D supplementation could delay the development of diabetes in over 10 million people worldwide.
SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeSystematic review·DateFeb 6, 2023
Researchers found that clearance of p16Ink4a-positive cells did not impact β-cell mass, but improved β-cell function and proliferative capacity in a subset of HFD mice. The targeted subpopulation of β-cells is non-proliferative and non-SASP producing.
SourceImpact Journals LLC·JournalAging-US·TypeExperimental study·DateJan 31, 2023
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Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Researchers at WashU Medicine discovered a link between obesity and diabetes, highlighting the importance of an enzyme in fatty acid processing. The study suggests that defects in this enzyme contribute to insulin hypersecretion and beta cell failure, paving the way for potential therapeutic interventions.
SourceWashU Medicine·JournalCell Metabolism·TypeExperimental study·DateJan 11, 2023
Researchers discovered that physical activity suppresses insulin-producing cells in fruit flies, allowing for efficient energy replenishment. This finding has implications for human health, as reduced insulin activity is linked to healthy ageing and longevity.
SourceUniversity of Würzburg·JournalCurrent Biology·TypeExperimental study·DateJan 4, 2023
Researchers found that xanthan gum-based fluid thickener decreases postprandial blood glucose levels by increasing Glp1 and Glp1r expression in the ileum. Additionally, the study reveals alterations in gut microbiome composition, favoring beneficial bacteria that produce short-chain fatty acids to protect intestinal cells.
SourceTokyo Medical and Dental University·JournalJournal of Functional Foods·DateDec 27, 2022
Researchers at Osaka University identified T-cadherin as a factor that feeds back a lack of insulin to pancreatic β cells, inducing their proliferation. This finding suggests a potential new treatment for diabetes by targeting T-cadherin.
SourceOsaka University·JournaliScience·TypeExperimental study·DateNov 7, 2022
A team of scientists has identified a key gene that enables beta cells to communicate with each other, enabling the pancreas to respond to glucose by insulin secretion. The discovery could help create replacement beta cells for diabetes therapy in the future.
SourceMax Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)·JournalNature Communications·TypeExperimental study·DateNov 2, 2022
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Researchers identified protein levels that were higher or lower than normal in tissues from individuals at different stages of type 2 diabetes. The study found a correlation between metabolic pathway disturbances and disease progression, suggesting new potential causal mechanisms for the disease.
SourceUppsala University·JournalCell Reports·TypeExperimental study·DateOct 7, 2022
A study by the University of Geneva team shows that disrupted circadian clocks lead to a rigidity in the membrane of pancreatic endocrine cells, affecting their function. The researchers also found that lipid profiles oscillate more during the day than previously thought, particularly in phospholipids and sphingolipids.
SourceUniversité de Genève·JournalPLOS Biology·TypeNews article·DateSep 19, 2022
A recent study published in Nutrients suggests that regular quinoa consumption can help prevent type 2 diabetes. Researchers replaced carbohydrate-rich foods with quinoa and found a significant reduction in post-meal blood sugar spikes. By mitigating this spike, quinoa may play a crucial role in preventing the progression of type 2 dia...
SourceUniversitat Oberta de Catalunya (UOC)·JournalNutrients·TypeExperimental study·DateJul 28, 2022
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers have found that infusing glucagon-like peptide-1 (GLP-1) hormone can improve impaired islet cell function in the pancreas of cystic fibrosis patients, potentially improving blood sugar control and treatment burden. The study suggests a new therapeutic approach for treating cystic fibrosis-related diabetes.
SourceUniversity of Pennsylvania School of Medicine·JournalDiabetes·TypeRandomized controlled/clinical trial·DateJul 21, 2022
Researchers at University of Basel found that the sight and smell of a meal stimulate an inflammatory response in the brain, which affects insulin secretion. In overweight individuals, this response is excessive and can impair insulin function.
SourceUniversity of Basel·JournalCell Metabolism·DateJun 30, 2022
A recent study at Tokyo Institute of Technology reveals that dopamine regulates insulin secretion through a complex of receptors, specifically D1 and D2. The discovery offers new insights into the mechanism behind this regulation and has potential therapeutic targets for preventing, treating, and managing diabetes.
SourceTokyo Institute of Technology·JournalDiabetes·TypeExperimental study·DateJun 22, 2022
A new study reveals that IL18 signaling is essential for β-cell development and insulin secretion, using specific receptors on acinar and β cells. This finding may provide insights into the role of IL18 in regulating islet β cell proliferation and guide future efforts to expand β cells and increase islet mass in diabetes.
SourceBrigham and Women's Hospital·JournalDevelopmental Cell·TypeExperimental study·DateJun 20, 2022